Beta Thalassemia: Causes, Symptoms, Diagnosis and Treatment

Welcome to my KZbin Channel Power of Knowledge Academy. In This video you will be able to learn about A type of Thalassemia called beta Thalassemia in detail.
What is beta thalassemia?
Thalassemia is a blood disorder that is inherited. This means it is passed down from one or both parents through their genes. When you have thalassemia, your body makes less hemoglobin than normal. Hemoglobin is an iron-rich protein in red blood cells. It carries oxygen to all parts of the body.
There are two main types of thalassemia: alpha and beta. Different genes are affected for each type.
Thalassemia can cause mild or severe anemia. Anemia occurs when your body does not have enough red blood cells or hemoglobin. The severity and type of anemia depends on how many genes are affected.
What causes beta thalassemia?
Beta thalassemia is caused by damaged or missing genes. Two specific genes are involved. There are several types of this disorder:
Beta thalassemia major (Cooley’s anemia). There are two damaged genes. This is the most severe form of this disorder. People with this condition will need frequent blood transfusions. They may not live a normal lifespan.
Beta thalassemia minor or thalassemia trait. Only one gene is damaged. This causes less severe anemia. People with this type have a 50% chance of passing the gene to their children. If the other parent is not affected, their children will also have this form of the disorder. This type is further divided into:
Thalassemia minima: There are few or no symptoms.
Thalassemia intermedia: This causes moderate to severe anemia.
Many people with this disorder are given iron replacement by mistake. This happens when a lack of iron is believed to cause their anemia. Too much iron can be harmful. So it is important to get the right diagnosis. You may need to see a blood disorder specialist, called a hematologist.
Symptoms of Beta Thalassemia:
Hypoxia, Hemolysis, Shortness of breath, Iron Accumulation, hepatospleenomegaly etc
Diagnosis of Beta Thalassemia:
Blood test, Hemoglobin Electrophoresis, genetic testing
Treatment of beta Thalassemia:
Blood transfusion, Iron chelation therapy and bone marrow transplant.
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