Aplastic Anemia - All you need to know - Definition, Causes, Symptoms, Diagnosis & Treatment

[@MedicosisPerfectionalis]

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Phenytoin

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Yes!

[@aditimandal1638]

Phenytoin

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Saaammmeee

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@@AbdulMaalikk what are u studying?

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Me too 😅

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[@crazyfangirlproductions6426]

This is a great video my sister has a aplastic anemia and we are getting ready to start the bone marrow transplant treatment for her

[@vikrampatil2245]

How was the treatment? How's your sister? Want to know everything about it

[@pravinjadgeri6980]

Hi I had a plastic anemia issue. But right now I have cure from it yes I have take allopathy(chemical) medicines. But later on I have shifted to ayurvedic medicine( natural medicine). After taking ayurvedic I have been healed/cured from it. completely Yes it can cured. And healed.

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​@@pravinjadgeri6980pls apu help me. What us the treatment. And how i conduct you?

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Bless her

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The answer to the question is D. Phenytoin Thanks for the tutorial. It really helped

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Phenytoin . Lovely explanation

[@MedicosisPerfectionalis]

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[@omerali2597]

Nice review of aplastic anemia! Just wanted to add that sometimes you can get a hypocellular MDS that looks similar to severe aplastic anemia. Usually cell morphology and cytogenetics will help you differentiate the two (hypocellular MDS you would expect more chromosomal abnormalities, aberrant megakaryocytes + megs will be small in appearance), however clinically they can look very similar. Thanks for the video!

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Great info and presentation. I am seeing a Hematologist tomorrow and this was very informative. Thank you.

[@MedicosisPerfectionalis]

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[@ecmobb8749]

Thank you AA patient. Recently diagnosed. This explains more than any doctor i have seen. Much love!!!

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[@invisiodisvy518]

This video is extremely concise and complete for a big topic of aplastic anemia. Came back here from reading harrison's. Contents can be confirmed as same. Thank you medicosis ❤

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[@TheThomprc]

Presently diagnosed with Pancytopenia, awaiting further evaluation. Your presentation is the the best I've viewed and highly reccommend it. Thanks for composing this video.

[@yamitsh95]

The Answer for the Question at 18:53 is Phenytoin, a Sodium channel blocker.

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[@MedicosisPerfectionalis]

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[@elenaprk5628]

Eltrombopag has been added to standard immunosupression for AA.

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You are realy great teacher Thanks alot my lecturer

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Phenytoin, thanks for your explanation and efforts ❤

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Thanks, helped out with my presentation on TERT gene mutations causing aplastic anaemia.

[@MedicosisPerfectionalis]

I am glad to hear that! Thanks for watching!

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Thank You❤

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Really awesome video ... excellent !!!

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Phenytoin.... Excellent and capsulated class

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Informative + fun, thanks man!

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Amazing video thank you so much !!

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Fantastic explanation

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phenytoin... awesome explanation

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I like you're special and simple way please keep going ❤

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Phenytoin... Nice one!!

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slow but very clear thank you

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Lovely presentation Answer is phenytoin

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Thank you so much, you are the best!

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thank you for the explanation

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I am trying to understand. It's so much fun. Thank you so so so much.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@Mazzawak]

Great video as always! I should note that Parvo-B19 very rarely causes Aplastic Anemia and is more often with Pure Red Cell Aplasia

[@MedicosisPerfectionalis]

True

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you are a life saver!

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[@yousefrezaei2979]

Beautiful explanation...well done

[@Bakbskshx]

i've applastic anemia. age:20years my doctor gave me horse atg with cyclosporine on 8thjanuary,2018.I'm also taking tab.eltrombopag 25mg but my platelet&hemoglobin count is not increasing.Last cbc report is below: HG-10.5,PL-34000,wbc-5.34 my hla type match is 10/9%. Now what can i do??? Please reply

[@maeb.6912]

Azmeer Hossan Joy I also have it for 3 years now 3 months ago I got a bone marrow transplant and I’m getting better

[@emiovy9594]

i have aplastic anemia too. i was given horse and rabbit ATG and i'm now in remission. i hope you the best of luck!

[@way2happiness400]

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[@mobrennanmcconnell7215]

My daughter starts ATG today. Praying it works for her with little side effects.

[@13litzkrieg65]

Got diagnosed last month with aplastic anemia, taking promacta, steroids and cyclosporine for 3 weeks now, waiting on chemo and stem cell transplant. The hardest part for me right now is dizziness and fatigue wish me luck, Im glad you all feel better , God Bless you.

[@banaalani7216]

Thanks a lot! This is very very very helpful

[@MedicosisPerfectionalis]

My pleasure 😇

[@rockycycle2682]

Another great Video, Thanks! Phenytoin

[@abukeabdela4928]

I am binging ur videos ...much appreciated ..why don't we consider aplastic anemia as one of the differential for dry tap as mylofibrosis or mylophtisis since it causes hypocellular bone marrow

[@khamikos1]

perfect presentation very helpfuland easily comprehensive/thanks deeply

[@MedicosisPerfectionalis]

My pleasure! Please share with your friends! Thanks a million! 😃

[@وليدالعليي-ه3ق]

thank you for your a nice explanation

[@MedicosisPerfectionalis]

It gives me great pleasure! You’re always welcome!

[@Am-yo4hx]

great explaination I hope you add video about Diamond Blackfan anemia

[@alshbah.e320]

What abour a megaloblastic anemia does has pancytopenia?!

[@juni_vlogzzz]

thank you sm for this ive been in the hospital for a month so hopefuly i can get a bone marrow transplant thank you

[@Sherry-ji3dc]

Very nice video, great 🤩

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Thank you 😊

[@tj7683]

Answer- Phenytoin

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OMG what a video, many thanks 😭🌹❤️

[@MedicosisPerfectionalis]

Glad you enjoyed it!

[@drinkspartypack]

I go to the same school Eric Connor went to, he is one of the eight people in the world who has had aplastic anemea.

[@MedicosisPerfectionalis]

Aplastic anemia patients are more than eight.

[@drinkspartypack]

@@MedicosisPerfectionalis sorry, that is my mistake, my gym teacher told me that there are eight, but apparently that is incorrect.

[@MedicosisPerfectionalis]

No worries...There are way more than that. Thanks for being honest and open-minded...I really appreciate that :)

[@analuisamartinez4597]

I was diagnosed with aplastic anemia with low rbc, low hgb, low hct, high MCV, but high reticulocytes, if bone marrow is not producing enough cells, why is reticulocyte count higher than normal? (Bone marrow cellularity is at 5-10%)

[@mustafacabdisalaan7306]

may b u had MDS[myelodysplastic syndrome has all you listed including hypercellular bone marrow]

[@elijahokoronkwo8610]

Could be relative reticulocyte count cuz its a percentage of whole blood. If it decreaces less than hct decreases then it’ll appear to increase. Theres a formula to get the adjusted retiuclocyte count in his earlier videos

[@reemalajmi4870]

impressive!!

[@MedicosisPerfectionalis]

Thank you 😊

[@shivampandey2363]

Are any curing of A Plastic Anemia other than bone merro transplant Plz reply

[@shivampandey2363]

@Rocio Ch. A. Rocio Ch. A. My Younger Brother Face with this from when he was of about 10 year old , And Doctor's was suggested for Bronemerro but we was not gone for bonemerrow. Now he is of 16 year old • And Blood transfusion has been happening every single day since last one week. And the doctor is speaking for the bonemerro😢😢😢

[@shivampandey2363]

@Rocio Ch. A. Now My Younger Brother is no more 😢😢😢😢

[@RR-we7iz]

Very very thanks for your nice explanation 🤓

[@MedicosisPerfectionalis]

You’re absolutely welcome! 👍

[@gamerberry2451]

Good day Sir, so I have a speculation as well as to why MCV is high is aplastic anemia.I’d love to know your thoughts. If MCV= Hematocrit(ht)/[RBC] This would mean that a decrease in [RBC] or increase in Ht should give high values of MCV right? We also know that in aplastic anemia, while Ht might remain the same (since all the other hématopoïetic cells are also affected), [RBC] is definitely low, hence giving high MCV values. Just a speculation, please correct me if I’m wrong😊.Thank you.

[@gerryadams2212]

MCV is also calculated via forward light scatter in flow cytometry. This gives each cell a direct reading of size

[@drisaaccardinalbwalya4409]

Much appreciated!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@mahiehussein]

Thanks 💖

[@mjk9152]

When I see the disease in the book, I feel disturbed by the many details. Then I search on KZbin and find a video for you. I am very happy, thank you very much from the heart💙💙💙💙💙💙💙💙✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙🙏🙏🙏🙏🙏🙏🙏🙏

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i need to know .... when I'll have like your science ... please tell us in other video about you and your studying and advice you can give it to us 💕💕💕 i love you from whole my heart ❤

[@MedicosisPerfectionalis]

Thank you so much 😊 I think I should talk about in the future

[@dr.ahmdooz]

@@MedicosisPerfectionalis i will waiting

[@MedicosisPerfectionalis]

Thank you 🙏

[@venukasharma1991]

please clear one of my queries not related to this video ....i.e why are neutrophils high in pregnancy state

[@MedicosisPerfectionalis]

Pregnancy is a physiological “stress” state.

[@asaku6248]

So it’s been a week and I’m living In hematology playlist 😂❤ I’m really having fun , I didn’t use to like hematology but now hematology really makes sense with your awesome explanation 😭💕🫧 And what makes me proud that all this wonderful work from an Arabian , I’ve told my whole family about that! , even my friends at medical school, with respect to everyone but really medicosis was my first line in every hard matter so that’s makes me more proud thank you sir , really Thanks alot for your hard and exquisite work ! Wish you life full of health and happiness 🤲🏻🤍

[@hdey8653]

11 years a go when I was 10,I was diagnosed with aplastic anemia, Now,no sign of it,but it has brought PNH

[@suryakantdongre3969]

Thank you sir

[@Wishyouendwell100]

How can we differentiate between the clinical presentation of megaloblastic anaemia and aplastic anaemia when both have pancytopenianin common????????

[@MedicosisPerfectionalis]

Clinical presentation will be the same. If there’s vitamin B12 deficiency, you might find neurological problems. The difference is on the bone marrow biopsy.

[@Wishyouendwell100]

@@MedicosisPerfectionalis I still watch your epic series since my 2nd yearMBBS 🥺 so grateful to learn from a great doc like you 🤗

[@safaabdulla2165]

Thank you

[@MedicosisPerfectionalis]

You’re always welcome!

[@fatemazoher3924]

thank you for the helpful video but the KZbin ads make it very difficult with the constant interruption. Any way you can prevent that ?

[@mahbubamaria1742]

I have a question. If there is anemia why there is no hepatosplenomegaly (for compensating anemia) Why there is no lymphadenopathy(as there will be increased infection) Can you please answer these. I can't find any satisfactory answer.

[@m2ym2y99]

@Medicosis Perfectionalis I had VSAA but was too old for transplant. Am in remission but still lacking stamina after 3 years. Is there a reason my oncologist didn't want me to take a vitamin B supplement after hATG, while taking Cyclosporine (Sandimmune) and Promacta? Every time I asked he would tell me to wait on that.

[@mishalahsan161]

How is your condition now?

[@m2ym2y99]

@@mishalahsan161 numbers are in the good range, but bruising very easily, and still lacking stamina. Grateful to be alive, try to live life as close to "normal " as I can.

[@michellebierman5]

I'm thinking I was diagnosed wrong. They said I had leukemia but it came back. But I was on nefdipine, And ani seizure meds for migraines. I was also diagnosed with thrombocytopenia, Meloydysplastic anemia. When they would give me iron transfusion my platelets would drop so low that I would need a platelets transfusion. Just didn't make sense to me. Please if anyone as an insight to what is happening. Please let me know because I have a appointment with a new oncologist/hemotologist next week.

[@raghdajalal5071]

Thanks ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤

[@MedicosisPerfectionalis]

My pleasure 😇

[@al21l51]

So it is low WBC and when blood is diagnosed they should show low in number. But again person can show leukemia. In other words, what will the WBC count be in acute myeloid leukemia and pancytopenia?

[@anna26970]

what about using Eltrombopag to stimulate platelet precursors and bone marrow stem cells to grow?

[@nairdarumani5450]

Today i have to learn aplastic anemia for my tomorrow hematology class and this video was absolutely amazing and very helpfull. I got only one question.. I have read that the hypothesis that aplastic anemia is a state before mielodisplasic syndrome is not so strongly approved according to the new findings in the genome. I dont know how true this is but i read some good arguements

[@MedicosisPerfectionalis]

Thanks for your comment! You are absolutely welcome! As for that theory, I am not sure, to be honest!

[@chathuranawarathna5300]

Thank you doctor. Is there any foods to supply indirect medicine for the pancytopania??

[@MedicosisPerfectionalis]

It depends on the cause. Unless you treat the underlying cause, it’s not going away.