Bone Metastases & Spot Radiation

Advanced #ProstateCancer Treatments | Eugene Kwon, MD:
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0:58 How and why does prostate cancer metastasize in the bones?
2:51 How common are metastases in the liver and lungs?
3:45 Can bone metastases cause noticeable pain as a symptom?
5:19 How is the pain from bone metastasis usually treated?
7:47 At what point would a patient have too many metastases to undergo spot radiation?
10:13 Where can patients find the best spot radiation treatment?
11:02 How effective are modern beam radiation treatments?
13:08 How does beam radiation affect PSA for oligometastatic disease?
14:47 How is a patient's treatment progress usually monitored?
17:07 Alex's conclusions
19:05 If you need help
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The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
#ProstateCancer #PCRI

[@ThePCRI]

Prostate Cancer Support Groups: ancan.org/prostate-cancer/ zerocancer.org/help-and-support/find-support-group healthunlocked.com/advanced-prostate-cancer

[@fotisiliopoulos4935]

Thank you so much for this series of videos. We highly appreciate them.

[@jerrymunroe4089]

I live in Florida in a rural area with a bad Medicare advantage plan. I have limited resources and hospitals and doctors. I have always been in good health but am 68 with a PSA rising every month to 16.5. Through listening to your videos, I learned I should have, and did have an MRI, which showed a lesion and other suspicious areas. I had the biopsy and was just diagnosed with Gleason 9 prostate cancer. I have a PSMA pet scan to check any spread scheduled next week, so my nightmare has begun. i live alone with two old dogs, but If I ever win the Florida lotto, I promise I will donate a portion to your cause. I have been watching these videos for the past year, and you are my support group and I have educated myself and learned so much through you. Thank you.

[@britneybeach6723]

I would recommend switching to a better Medicare advantage plan such as Aetna premier plus medical advantage. It's national wide so you can go anywhere in the USA. Good luck

[@andrewkosalka3843]

Presently I am going thru radiation treatment and hormonal treatment for my metastatic cancer at the Dattoli Cancer Center in Sarasota. In addition to these treatments I am taking a drug called Erleada that suppose to work on cancer receptors. It is my second time that cancer came back after initial treatment. My previous treatment was three years ago and I had five lymph nodes radiated. My PSA before this treatment was 1.45 and PET scan reveal that I have 6 spots with cancer on 4 ribs and probably on 1 lymph node under my left armpit. After 3 weeks of treatment and only half of my cancer spots treated my PSA went down to 0.074. Doctor Dattoli is telling me that this time he will cure me. I feel great and physically very active, greeting.

[@keithcolegrove2924]

So happy to hear a positive story!!!!

[@stanleymoore8084]

I was told by my dr that life span is 20 months

[@koof1776]

​@stanleymoore8084 So your doctor's surname must be "god", very unprofessional prognosis~

[@mahersaleh1085]

Alex, simply you are the best presenter who knows how to sooth the pain of some one who has problems with prostate disease. 🌹

[@isaact7572]

you guys are the best !!!!!! I have the notification on. I watch every single video as soon as you upload them on youtube :)

[@dcplunkett]

I regularly participate in two online support groups, and it has proven to be helpful and comforting and even entertaining. Recommended.

[@alannahurst3894]

Could you share this info? My FIL was just diagnosed

[@dcplunkett]

@@alannahurst3894 Both are Facebook groups. Prostate Cancer Warriors is one. The other is The PC Tribe.

[@walterpitt1775]

This is what happened with my father in the early 1980s. His prostate cancer spread to his bones & pretty much got into every bone according to the doctors. He quit treatment as he was a pharmacist he pretty much knew what the results would be. His last couple of months were terrible.

[@gulshani8331]

How many years he survived?

[@s.chaisrisuk4956]

Sir! Always encouraging!

[@c.a.parker5036]

Thanks PCRI!

[@tomswoverland]

Thanks for your videos I have been treated for Gleason 8 for 4 years after all the treatments I just finished Pluvicto and finally in remission hoping to stay that way. It’s been a long journey and with all the metastasis never have been in pain but thanks for the info in case I do I will know what to do. Good luck to everyone here’s to being undetectable and living long.

[@robbieru]

That’s great Tom! I was diagnosed with Gleason 8 a couple of months ago , as we “speak” I’m going to have a PSMA PET scan be done to see if any metastasis has occurred. I would like to to keep our conversation and perhaps pick your brain on your recovery process. Thanks for sharing. Cheers!

[@salsamink]

Thanks for the video on this topic.

[@mcresearch]

Thank you.

[@PatB415]

Thank you both for this priceless info!

[@olivergrossettolivergrosse3116]

God bless

[@gdadc2649]

invaluable information thank you

[@TheRm65]

Greatly appreciate your videos.

[@DCGreenZone]

For what it's worth, Glasgow University is adding Mebendazole iirc, to Docetaxel and City of Hope, (AOH1996 fame) is adding Ivermectin to TNBC treatment. Ask yourself why.

[@ThePCRI]

Advanced #ProstateCancer Treatments | Eugene Kwon, MD: kzbin.info/www/bejne/Y4O5h6Rmqql0e6c

[@johnchambers12]

My PSA was undetectable for almost 2 years i am now at 1.18 i just got my PSA Pet today.

[@ThePCRI]

Please reach out to Helpline if you need information or help: pcri.org/helpline

[@patricktrussell7465]

Any news on AOH 1996 ?

[@eddiegardner8232]

Just a simple question, how many Greys of radiation are generally used to "kill" an oligometastatic bone lesion (as opposed to just pain reduction of it)?

[@paulhafner9781]

How many gray can sterilize a bone met?

[@NarcFreedom]

What or where are the centers of excellence referred to here?

[@bobliening5783]

I appreciate all your videos, especially this one. I do have a question about the last bit of info though. I think you said if you are “undetectable”, under .1, and a PSMA PET Scan shows a couple of hot spots, to go ahead and get them radiated. I’m not questioning this course of action, but if a person has been undetectable for 20 months (like me at 0.09) my oncologist says I don’t meet the standards for a PSMA PET Scan. Is the only way to get a scan is to have specific bone pain?

[@wjrothrock3]

I am in almost the exact same situation. I was diagnosed a little over a year ago and had a PSMA PET Scan that showed metastasis in several spots on my pelvis and tailbone. My initial treatment plan involved radiation to my prostate and one lymph node which I completed 6 months ago. My radiation oncologist wanted to wait after that sesion for 6 months before he treated my bone mets in order to let the tissue around my prostate heal and to prevent damage to my colon from too much radiation. My oncologist ordered a bone scan recently and that showed that most of the mets had decreased significantly in size as a result of my ADT therapy (Eligard, Abiraterone, prednisone). Before I start the second round of radiation my radiology oncologist wanted to order another PSMA PET Scan, even though my PSA is less than .06 (and has been since I started ADT). His reasoning is that it has been a year since my last scan and he wanted to fine tune his radiation targets on my pelvis and tailbone with the new scan. He ordered the scan and it was approved and I am scheduled to have it in about a week and a half after which they will schedule the additional radiation.I thought that maybe I wouldn't qualify for the additional PET scan because of my undetectable PSA but he said because they know I have metastatic disease he could get it approved.

[@bobliening5783]

@@wjrothrock3 I’ve not had radiation, surgery, nor chemo. I would be interested in tour results.

[@1royalpalm]

When I was going through chemo (jevtana) I started to develop pain in my right hip (lower part and upper part). My oncologist noted I did have some hot spots in my hip based on a previous PSA PET scan. He sent me to a radiologist-oncologist that radiated (just one session) of my right hip. Within five days all the pain was completely gone. Since I was on chemo I expected my PSA to immediately drop, but conversely my PSA ticked up some. At that point my oncologist (since I was eligible) sent me to a nuclear doctor that put me on Pluvico treatment (lutetium-177). I recently finished up my six 6-week cycles of Pluvicto. I'm disappointed as my PSA was 0.22 four weeks after my last Pluvicto cycle. At the conclusion of my last Pluvicto cycle my oncologist put me on Xtandi -- in addition to the Lupron I've been on for five years. I don't know where we will go from here if my PSA starts to rise.

[@luvmechanix]

You can get more pluvicto. I have seen it approved before. There is also an immunotherapy that particularly protects lymph nodes,I forget the name...

[@luvmechanix]

There is also IV vitamin C, melatonin/statin/aspirin and other alt treatments.

[@bobliening5783]

I’m on Xtandi and Lupron. Started at a PSA of 1,300 and Gleason score of 4+5=9. It took about 4 months to bring my PSA down to 0.09. It has been stable there for the past 20 months. Oh, and Mets all up my spine, several ribs, and Lymph nodes. YMMV

[@1royalpalm]

@@bobliening5783 Prior to any chemo I wa s on lupron or eligard. When my PSA started rise my urologist put me on erleada. That brought my PSA down to undetectable for about a year, then it started to slowly rise again. It was then I went through chemo and pluvicto. I'm on xtandi now because I'm also on blood thinner, and my oncologist said there would be some kind of negative interaction with erleada and xarelto (blood thinner).

[@isabelonate2145]

@@bobliening5783Were you in pain? Since it was in your spine? My father also has metastatic cancer in bones at the moment.

[@joemaxwell1044]

I know I sound foolish so please forgive me. How do I subscribe to this channel?

[@richdannys2906]

There's a subscription button with a Bell icon, directly under the video... Click "Subscribe" until it changes to "Subscribed"..

[@TK-123]

Thank you.