Can steroids save your life? - Anees Bahji

Explore the science of how corticosteroids sneak into our cells to help fight allergic reactions, rashes, asthma, and harmful immune responses.
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Steroids: they’re infamous for their use in sports. But they’re also found in inhalers, creams to treat poison ivy and eczema, and shots to ease inflammation. The steroids in these medicines aren’t the same as those used to build muscle. In fact, they’re all based on yet another steroid- one our body produces naturally, and we can’t live without. Anees Bahji explores the science of corticosteroids.
Lesson by Anees Bahji, directed by Nick Hilditch.
Animator's website: nickhilditch.com
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[@weegeeismad9298]

1:52 The only true way to hold a cup.

[@madil2259]

Especially in the winters.

[@trolgar9749]

Lock down 0

[@trolgar9749]

ya

[@vincenta7104]

The italian way*

[@psychic-lizard]

JackSepticEye would like to know your location

[@sarveeshganesh8440]

I knew corticosteroids are anti-inflammatories but I didn't know how it worked,so thanks TED!!

[@antty3380]

-Ed

[@lostpattern9407]

-Teddy

[@riflo1959]

-Edd

[@QuestionEverythingButWHY]

“If we knew what it was we were doing, it would not be called research, would it?” ― Albert Einstein

[@darthmalice7464]

@Δημήτρης Μπαλφ u can't shut up a bot lol

[@paemonyes8299]

Δημήτρης Μπαλφ how do you tell a comment is a bot bcos I think I’ve seen one before but idk

[@yeetthephone2341]

Six nine likes

[@inactive6200]

Δημήτρης Μπαλφ the channel’s very sketchy

[@zealousdoggo]

@Δημήτρης Μπαλφ um how is quoting Einstein promoting a yt channel

[@jerry3790]

Amazing how quickly they released this after the recent study showing a steroid has the potential to treat COVID

[@mysterymen8486]

Really? Cane you send the link I really want to read it

[@vnrays3775]

Steroid can’t treat covid-19, it just lower the immune effects, so it helps with long-term survival rate.

[@dennysdonuts4918]

It's probably a coincidence or they deliberately pushed it's production speed after the news. Videos take a really long time to make, like every five mintues can need 20 or 30 minutes of editing, depending on what you're doing, so it's more likely to be a coincidence than intentional.

[@Sashhh-mk6gw]

@@mysterymen8486 just type up dexamethasone

[@pg3dvideos81]

Bro is a normal flu wake up

[@QuestionEverythingButWHY]

“Somewhere, something incredible is waiting to be known.” ― Carl Sagan

[@SnoopyDoofie]

God ...or Dog - Depending on which way you spell it.

[@marcferdinandiibas4971]

Δημήτρης Μπαλφ y should he?

[@zealousdoggo]

@Δημήτρης Μπαλφ beep beep beep boop buup robot says No U

[@aMiimo.n]

I really like this art style!

[@viofrostline9289]

Its roblox style

[@Aluxix]

No

[@prakharchaudhary9797]

No

[@toxoids]

No

[@gabrielle-d1b]

I like it too

[@prakashrawat8734]

"Happiness is having a scratch for every itch" The single best quote ever. I am gonna devote my entire life completely towards following this. Dorime🙏

[@jessicapink703]

They certainly saved mine, they were important part of my chemotherapy when I fought Leukemia and fighting off the neurotoxicity that came as a side effect of the chemotherapy drugs.

[@noinfo3517]

"Can steroids save your life?" Well yes, but actually no.

[@ye4045]

It saved my life I was going to die no cap

[@tropical_flak]

You can use the cortisol to stop the cortisol, lol

[@__WinstonChristianoWiradinata]

This has explained everything, steroids is good but shouldnt be use too much

[@cookiecakeeater6340]

897th King of Judah ONE of the COVID treatments is a steroid, there are a lot of different COVID treatments

[@winw4548]

@897th King of Judah Misleading. Steroid don't treat covid-19. In severe cases, with severe respiratory symptoms that need ventilators steroid helps by reducing inflammation and suppressing overactive immune system that might cause cytokines storms. Steroid don't kill the virus. It has no roles in covid-19 cases with no symptom- moderate severity cases.

[@erasier_1991]

Hey Ted Ed... Y'all forgot to add that long term steroid use switches off the mechanism to produce cortisol. I have been on a steroid inhaler for asthma since I was 2... At the age of 25, I was diagnosed with secondary adrenal insufficiency... Why didn't y'all mention that?! Also long term use of oral steroids in patients with lupus, hepatitis C, COPD etc has found to have a significant increase in the cases of secondary adrenal insufficiency!

[@carloalbino]

For real. There are so many downsides to steroids. Topical steroid withdrawal is a condition that happens when you stop using steroids for treating skin conditions like eczema. Steroids can be useful in emergencies, but I think humans have become too reliant on them to treat chronic conditions. Steroids are not cures, they just hide symptoms.

[@Aaron_Walker_011]

Yeah, basically long term steroids supress your body's own steroid production. And if u withdraw then suddenly, it can take time for your body to adjust back (in weeks), even as steroids are vital for some life functions (=need them daily). Thus leading to a very dangerous situation, which CAN be FATAL. Thus, whatever the cause for starting, Steroids are always TAPERED OFF (meaning their dose is gradually reduced over weeks to months until Zero). If you just stop taking them one fine day, you are risking a lot. Also, inhaled steroids aren't that bad, cuz the effect is mainly on the respiratory system, but years of use & yes, you should consult an expert before deciding to stop.

[@Aaron_Walker_011]

They aren't mentioning all the important facts, but they did cover a lot of basics in 5 mins. Steroids aren't just pills you can pop in whenever you want. Even for preventing Coronavirus. The study was controlled & people were in settings that could help nullify the negatives of steroid intake. It's not something you should try at home

[@winw4548]

Cost over benefit. Steroids are necessary for those diseases because otherwise it means death. 1.Lupus leads to organ failure that will need transplant without steroids. Transplant patient will likely need to take immunosuppressant llike cellcept after that which is more expensive and rejection rate are high. 2.Asthma: Pt given steroid if needed, Controlled asthma dont need steroid in most cases. Frequent asthma exacerbation will cause lung tissue damage. Systemic steroid should be given based on presence of inflammation in lungs only. 3.COPD; patient with high eosinophil count will benefit with steroid use.Otherwise long acting broncodilator will benefit patient. With copd unlike asthma the damage is irreversible so when needed it can be used. All these use of steroid are based on cost and benefit, with clear benefit. The concern would be more to inappropriate use as a magic drugs for pain, sore throat and as such. All medication have side effects. Why they have to only mention adrenal insufficiency? When steroid have long list of it, osteoporosis, gi bleeding, cushing syndrome, withdrawal syndrome and much more.

[@winw4548]

@@carloalbino Yes, people tend to look for the "best, fast and strongest". Steroid is not the mainstay treatment for eczema but emollient is. But since steroid shows effect faster, people tend to go for that and selection of steroid also matters with consideration of age,severity,site and chronicity of eczema. Long term steroidal need monitoring under skin specialist every 3 monthly but people tend to get it over the counter and most don't even know finger tip unit practice for steroid .

[@janice9752]

I have eczema since I was born and had used steroids to keep my flare ups in control. Right now, I’m undergoing Topical Steroid Withdrawal syndrome and it’s definitely one of the hardest things i have to go through in my life.

[@erasier_1991]

I feel for you. I have been on steroid inhalers and steroid creams since I was 2. I came off them and was then diagnosed with secondary adrenal insufficiency. PLEASE keep an eye out, if you start feeling extremely fatigued and are getting weird symptoms. I really do hope that you get through the withdrawal OK 💜

[@datawizard130]

Ted Ed : can steroids save your life? Me: Baseball tried that already to make the sport more exciting

[@blabla-rg7ky]

baseball is a sport?!?

[@hex5884]

what's a baseball

[@a_akie]

I've been using corticsteroids on and off for as long as I can remember because of asthma, allergic rhinitis and eczema. This video is really well delivered even though I already know what it does to my body. Thank you for this!

[@richardsackler7627]

Yeah it accelerates aging with a plethora of horrible side effects.

[@dogethedog5057]

His voice is so soothing

[@weegeeismad9298]

*All I got from this is Cortisol does something good and bad.*

[@Aaron_Walker_011]

Also - More bad than good over long term exposure. Even with chronic inflammatory conditions, they have to shut off medicinal steroids at some point, give a break & restart it a while later. Basically, it is an excellent way to control severe inflammation (like asthma attacks not responding to typical inhalers). But since it messes up with DNA expression = in cell signalling, it can be a double-edged sword.

[@GabrieleirbaGabrieleirbag]

In a nut shell,yea.

[@mbbbits4847]

You make reality more comprehensible. Thanks Teded👍

[@betawarier346]

I don't know why but TED-Ed always knows what kind of videos I need.

[@ajithsidhu7183]

@TED ED pls do one how to cure mental illnesses and jurisprudence

[@thenotred]

Oh no...it's chemistry The only subject that I failed

[@britneyborja8566]

Aswell as Biology and Anatomy & Physiology with subjects in immunology and medical applications 😊😁

[@zaimzainal6635]

@@britneyborja8566 chemistry....and physic. They are the hardest

[@fraxizztv6433]

Walter White is not amused!! Apply yourself!

[@chinulondhea3985]

Ted ed I love your videos♥️♥️♥️♥️♥️♥️

[@landorsea7154]

Loved the video! :) But I noticed at 4:54 irritable bowel syndrome (IBS) was mentioned instead of inflammatory bowel disease (IBD). These can both be unpleasant to have and are commonly mistaken for each other but only IBD is treated with steroids because it’s an inflammatory disease rather than a sensitivity of the colon. Thank you for any correction! Sincerely, someone with IBD.

[@techblizmax9660]

Yes I hate that misconception:(, I have IBD too, how are you?

[@toasterstrudelboy6934]

All the how fun and how the videos are educational

[@souravbiswas-sw4yn]

Son:- why's my sister named rose? Father:- because your mother love roses Son:- ohh cool, thanks Father:- no problem anabolic steroids

[@aryayudha6414]

Corticosteroid are a blessing for people with autoimmune disease.

[@raemckay]

Great video, as always. A note: at 4:53, the video mentions "Irritable Bowel Syndrome" when it should have mentioned "Inflammatory Bowel Disease". IBS is not the same as IBD (which steroids treat) like Crohn's Disease or Ulcerative Colitis.

[@tayla83i]

Deffentinly IBD and IBS are very different

[@yannicktati8834]

so testosterone can help with crohn ?

[@Molly-ss4fw]

The only upside to having pathetic asthmatic lungs is that I get to make the same "I'm on steroids" joke every time a friend sees my medication

[@blueharkgaming4751]

Just came here to comment when I saw that it was uploaded just before 59 second s

[@Alkalus]

Great. Now we need steroids to fight COVID-19.

[@matheussanthiago9685]

a major study from UK just yesterday announced its result about the use of dexamethasone, a largely known and long approved steroid, on increasing the survival rate of patients on ventilators this vídeo apparently isn't covering this particular discovery, but goddamm what a timing

[@DanielQRT]

@@matheussanthiago9685 TED-ed videos take a couple of months to be made

[@blitzdream3683]

I had steroids when I was a baby, when I was a baby I had a worst flu ever, my throat filled up and I couldn’t breathe and I’m starting to change color so my parents quickly rush me to the hospital, then the doctor helped me to breathe, later the doctor said to my parents if you guys waited another 5 minutes then your child will be gone, then the doctor said we could give your child steroids then she’ll have 70% chances of staying alive and if we not give her steroids then she’ll have 25% chances staying alive, so then my parents pick steroids. So now I’m here alive, now I’m much more stronger and my wounds heal faster than other kids my age😅

[@aseemsaini4688]

Thanks to TED ED for their continuous informative work in a visual appealing manner. Love to watch and learn ✌️✌️✌️

[@deanab-se5op]

Just looked up corticosteroid cream this morning and now TED-Ed covers this topic!

[@YashBhatter]

TED-Ed - Can steroids save your life? Audience - Can TED-Ed MAKE my life better? Answer - 100% YES. And hence I try to do the same with the videos I post, trying to make others' lives better 😄

[@par9362]

Yash Bhatter Hey this is a copy of a comment I made

[@YashBhatter]

@@par9362 I didn't copy your comment. Looks like we think alike 😊

[@par9362]

Yash Bhatter hm I’m suspect 🤔

[@joyexplores]

❤ the graphics😊

[@Ninong_NEIL]

Sending love especially the narrator

[@AlaePulli]

The progesterone molecule looks wrong...

[@hunyotiago1271]

Did you hear about the Italian Bodybuilder? He loves astrophysics! He even said: "I love-a steroids"

[@elliotfinn146]

I love how Ted-ed changes their animation style for every video!

[@sphakamisozondi]

01:23, 01:27, 01:47, 01:50 Those sound effects are soo satisfying.

[@SamuelSamuelSamuel1]

I’ve taken Dexamethazone, everything hurts, your dizzy, you can’t sleep, it’s saved my life when I get severe asthma attacks, BUT IT SUCKS

[@FabulousCooki]

I thought this might have been a video linked to the Covid update relating to the steroid dexamethasone being found to improve the survival rate in the UK :o

[@matheussanthiago9685]

yup, so did I I guess it was just a case of incredible timing

[@jaybariya9]

Thought the same thing.

[@CellRus]

it definitely is! Its a calculated way TedEd does so that by the time its approved or disapproved, people will know what steroids are and dexamethasone!

[@alexisjimenez6522]

It's related, COVID induce a Systemic inflammatory Response, which is an overproduction of proinflammatory cytokines, so antiinflammatory drugs, incluiding corticosteroids are used to control the cytokine storm.

[@FabulousCooki]

@unregisteredhypercam 12 haha my bad! 😅

[@Seb_No.13]

I have a question related to EpiPens. How do they work?

[@yeetthyannoyingchild2346]

Those eyes of the people the way they move....ooh. I still am stuck on the phantom traffic video for the cool and calming swearing voice

[@weegeeismad9298]

TED-ED is either happily enlightening or hurt fully truthful.

[@sariaanjum3421]

This video right after the study release about Dextromethosone helping in COVID death prevention

[@lambdacoder4321]

Good knowledge + good animation + good narration = Ted ed.

[@adylaar6708]

Answer is yes. It reduces inflammation and thus reduce pain. Best use for acute inflammation like gout, severe allergies etc.

[@atman4437]

Who ever got that space x add in the beginning of the vedeo

[@tiamelancholyjeoncockity]

I made sure to reread the title at least 4 times.

[@tahmid6399]

I have subscribed to Ted ed almost 4 week ago and from then I am in love of these vedio..They are very informative...Thanks Ted ed..

[@scienceandknowledgearchive8197]

Thats so great and informative. Love you Ted-Ed

[@D99IVYANAHU]

The most informative channel on KZbin.

[@opus53waldstein70]

Thank you Addisson, the official TEDed voice 😀

[@arjundubey3611]

great way of explaining ....can someone tell what softwares are used to make a video like this

[@SamuelSamuelSamuel1]

Adobe something?

[@maxhill9254]

thx

[@aloyperez2059]

Is it wierd that i hum to the tone of ted-ed's intro every video?

[@powjamaica]

Just because other signalling molecules have to bind to the outside of the cell, doesn’t mean they are slower. Because corticosteroids alter gene expression, they actually take much longer to show their effects, than many “extra-cellular signallers”.

[@AnnAdventures]

Great vidz.. I enjoyed watching. Coz i learned a lot thanks

[@harshshukla2412]

Happiness is having scratch for every itch -Ogden Nash Happiness is listening to Ted ed vedios with narration by *Addison Anderson* -Me

[@auro1986]

this is why use of steroids must be legalized in sports competitions

[@0901강민재]

스테로이드는 언제나 몸에 나쁜 영향을 끼칠 수 있다고 생각 하였지만 알레르기 반응과 같이 위험한 면역반응을 스테로이드가 막아주는 중요한 역활을 하는 것이 가장 인상이 깊었습니다. 이렇게 배경지식을 만들어가니 세상이 조금 더 다르게 느껴지는 것 같습니다. 감사합니다.

[@djtechzz]

School : steroids are bad Ted Ed : yes but actually no

[@strange_and_magnificent]

This video’s animation is AMAZING 😉! 👍🏻👍🏻👍🏻👍🏻👍🏻❤️❤️❤️

[@mjstory1976]

Awesome and informative video

[@slimp4644]

1:06.... Tetravalent oxygen in Progesterone?

[@jorenzlorenz]

The solution to everything: steroids.

[@toasterstrudelboy6934]

Heck yeah

[@charles9391]

Djorz apparently even CoViD kzbin.info/www/bejne/paqsmIqoi9eNgKs

[@CellRus]

Dexamethasone vibe! Its good to start preparing people the knowledge they will need

[@RajTiwari-op9jm]

A neet student at 0:42 ... Oh that's canabenoid

[@nintendofan222222222]

1:52 *THE cortisol*

[@yuriarin3237]

it would be cool to have a video on autoimmune diseases generally! :D

[@vanithanallathambi5761]

This is really informative but I don't seem to understand anything 🤪🤪

[@Mayurbhedru]

This is bad information because it is assuming your medical knowledge.

[@vanithanallathambi5761]

@@Mayurbhedru wha?

[@Mayurbhedru]

@@vanithanallathambi5761 this video contains too much information and speed past many things. Only people who is medical professional who know he want to say. He is simplifying which doesn't work for who does not have basic knowledge already.

[@KalRandom]

@@Mayurbhedru I agree, going to have to watch is several times to try and make out what there actually saying. I have shots in my back or hips every 3 months for pain issues. This video went over things so disjointed and quick I couldn't get any information from it. Just word salad.

[@akiv33401]

This is really funny. 🤣

[@dodkiwi]

no offense but you inverted the C and the O on the ketone of progesterone at 1:08. i'm very fond of this molecule, please write it correctly

[@ty42subsicreatedamazingvid48]

I have asthma and was out on ten different steroids last uear before corona for my steroids and exma and am know healthy

[@dennysdonuts4918]

Kind of a "too much of a good thing is a bad thing" situation or a "between a rock and a hard place" situation.

[@rebilgroup3440]

Thanks Ted-ed

[@napoleon_bonaparte_the_great]

History vs Philipe Petain?

[@fitrianhidayat]

Anees bahji sounds like an Indian name, so I was pleasantly surprised that your English is very good

[@Sopranaur]

science wouldn't be so much fun if it isn't TED-Ed

[@biggerbegansmallerthanus8583]

What about skin whitening creams that contain steroids? What are the exact reasons that they are so dangerous and how do they work?

[@abcdefgh-rq3gq]

Eat clen. Tren hard. Diabolish Corona Virus. Anavar give up. 🤣Just kidding.

[@jupitired777]

ooh nice I never knew this

[@freesaxon6835]

Of course

[@that1828]

Where's the guy in the start

[@Lifeisconfusingimlost]

Cool video

[@JakeyBoy1]

Instructions unclear, just won 4x Mr. Olympia

[@djtechzz]

When Ted Ed teaches you more than school

[@harithwijeratne872]

Awesome video 😍❤️

[@hiteshbhatt6445]

Me:0 views after a month Ted ed:2K views in 10 minutes

[@clvsidy]

Who’s watching during quarantine?

[@gothicdragonwarriorqueen5819]

Interesting!!!🙂❤👍

[@omsingharjit]

So it can also me used in Respiratory infection like caused by covid ?

[@PK-lr8mh]

Who would have thought that steroids could save live from Covid19.

[@SamuelSamuelSamuel1]

I’ve taken Dexamethazone for my asthma, it’s saved my life before

[@ΝαταλιαΘεολογου]

Interesting!🧐👍

[@fringedwig4670]

u should make a video talking about the difference from a male to a female

[@ognjen1611]

I watched enough House M.D to know that almost everything can be cured or postponed with steroids :D

[@coyoterunner1126]

Here i am with having struggled for a very long period with acne and walking around literally every day so tired because of a high(or low?! Dont even know and tests didnt gave me any proper results) cortisol.. if anyone shares or shared the same thing please feel so friendly what had helped.. 🙂

[@lennaerthondelink7374]

Immune system: I wonder what this button that's labeled "self-destruct" would do *Presses it *

[@xBorisD]

This is literally better education than school.

[@minamigokita8692]

Why am I so fast

[@riflo1959]

Lmao right when I got steroids after having a allergic reaction good timing TED!

[@Dragon-Slay3r]

We playing III again? Where did the trucks go? 😭 The testicular cancer steriod something to do with this