Challenging Bryan Johnson On His “Never Die” Biohacking Protocol

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Bryan Johnson began his life as an entrepreneur, buying, selling, and growing companies like Venmo to build a healthy living for himself. Several years ago, he became fascinated with the idea of maximizing human technology to extend the length and quality of one's life as far as possible. Today, he lives as the most tested man in the world at the center of "Project Blueprint", where drawing on his access to wealth and resources, he pushes the boundaries of human existence to see if he can become the oldest person of all time. As someone who has pushed back quite strongly against biohacking and "optimizing" one's health beyond homeostasis, I was fascinated to ask Bryan about his approach to life and fact-check him on a few of his theories.
00:00 Intro
01:42 Baby Steps From Superintelligence
14:33 Tracking Your Life
21:28 Overpopulation
24:55 Colon Cancer / Testing
30:08 Lessons For Normal People
36:32 Plasma Transfusions From His Son
42:11 HGH Harms
44:50 Sleep Tracking / Sleep Score
50:30 Harms Of "Don't Die"
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Executive Producer: Doctor Mike
Production Director and Editor: Dan Owens
Managing Editor and Producer: Sam Bowers
Editor and Designer: Caroline Weigum
Editor: Juan Carlos Zuniga
* Select photos/videos provided by Getty Images *
** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional **

[@danieljohnsz]

The thing I like the most about this interview is that Bryan legit sits there and thinks about the questions and his response before answering. A lot of people have a preset agenda and the answers just roll off their tongue because they aren’t putting any thought, just reading from their mental flash cards.

[@elizabethtorres2132]

Yes i enjoyed that too

[@alfiewright1396]

He definitely has some preset agenda to some extent

[@Zephyr425]

​@@alfiewright1396if he didnt then this podcast wudnt exist lol

[@alnewick]

Yep. Bang on observation.

[@MrZebanHai]

Did we watch the same video? I feel like Bryan spent half of the time dodging questions or just coming up with some bs on the spot. He did not sound like a well educated individual here. An eloquent and verbose "I don't know" is still just "I don't know."

[@nicholascantelmi9534]

We all thought this was an episode on health, but it’s actually a masterclass on how to have a respectful conversation. Incredible

[@jzmn0033]

Yeah 😂 I keep thinking I'd be stretching some mental/politeness muscles throughout the whole convo

[@joemama8243]

that was a master class of how a non doctor rekt a doctor lol

[@derekderek2570]

@@joemama8243😂 that’s what I got out of this too, but Brian is a supreme genius and he’s talking to a very intelligent doctor. They are just on different levels of intellect.

[@AmandaGrey-ss5bb]

I'm still amazed that they were both able to keep their cool.

[@anovosedlik]

Dr Mike killed it (no pun intended). Bryan ... ooof. I'm sure he's lovely.

[@Roger_808]

it was inevitable that someone like brian would exist. and thank god it was him. hes so open about all the things he does. hes honestly the best person to be doing this.

[@constructenglish1]

Very good point. I like him

[@vernon121]

It’s fortunate that he also has the financial means from his company’s success to fund his project. Had he been some average wage earner, his dreams would probably just stay as dreams. We’re extremely fortunate he’s using his wealth for the benefit of human health. Imagine if all billionaires used their wealth like this - to solve global challenges. Utopia would probably be reachable.

[@un1kum42]

The problem is that he is using a lot of stuff all the time. He can be measured as often as he wants, but if something positive changes through a new drug you cannot tell if it was really through that drug or treatment or if it was the combined effect of all stuff together and every one thing alone wouldn't'd do anything, or he has started a new treatment a month ago, then the next one, something good happens, everyone thinks it was the second treatment, but it was the first or the one before just acting a little late. I don't think that what he is doing is clinically viable and can only lead to traces of new knowledge.

[@dogdjinn]

@@un1kum42 it would still narrow things down REALLY drastically though. tbh starting from the maximum amount of things thrown at the wall, getting a positive, and then narrowing it down to a smaller and smaller subset repeatedly seems like the most efficient way to me

[@AhmedNaguib1]

Others have done it but less openly and by experimenting on others not themselves.

[@thabulos]

I thought Bryan was obnoxious when he first went viral with what he was trying to do. Every video I watch of this guy he grows on me. After this video I like him even more. His super power is he never gets defensive when he is being criticized. I wish I can be like that more.

[@anovosedlik]

stan

[@KingNStheMighty]

For sure. I, for one cannot believe the amount of criticism this guy receives for DARING to further progress within science that could lengthen my own lifespan. It's honestly baffling. And he always sits there and takes it like a champ, answering honestly and with reflection.

[@thabulos]

@@KingNStheMighty Well said! Couldn't agree more!

[@Sindrijo]

That's probably because he´s actually put some deep thought into it, and also, self-criticised it a lot and genuinely views critique as a path of improvement.

[@thabulos]

@@Sindrijo Very true! Good insight!

[@normang3668]

Me sitting on my couch eating potato chips: 'Bryan has some really good points."

[@stretchkitty21]

Lol

[@daan260]

living forever is a good point?

[@maymayyyy]

​@@daan260 improving life expectancy is

[@MandyMoon12]

Oooo what flavor?

[@Drewsvids-rf1mj]

Yeah what flavor?

[@Appp21]

I like how Doctor Mike always has an open mindset with any conversation or belief

[@lifestylelines]

Yes. He’s an amazing communicator / host ❤

[@Dontbustthecrust]

Ehhhhhhhh....

[@kroneexe]

@@puffdaddy69open mindset doesn’t mean just going along with falsity.

[@FrancesoCamarda9]

thats why we need david goggins next. dr mike is such a great podcaster

[@thisiscait]

Naaaah I wanna see him get sassy at obvious crackery

[@sriramananthakrishnan138]

My biggest takeaway from this is that when Bryan is challenged on his methodology he doesn't get defensive as so many others do, he simply states that he doesn't know and presents his argument as to why he believes it will work and how he is objectively measuring it.

[@KatieDeGo]

I admire this dude for performing these science experiments on himself, at least, instead of other people.

[@yashtrivedi2717]

Dr. Mike asked the best possible questions without creating an argument, And Bryan answered all those questions in the best possible manner..! It's a sign of a very good podcast. Edit: I've watched the entire podcast..!

[@aciuschristophores7789]

And what a well-worded compliment you gave too, brother!

[@simonstanton5299]

​@@aciuschristophores7789And what a well worded reply!

[@twincherry4958]

They are both extremely intelligent and well to do.

[@ABc-nu6jb]

Brian is obsessive compulsive to say the very least but what many ppl forget is that he makes money off this whole thing

[@jerppazz4525]

@@ABc-nu6jb puplic experiment that costs millions to upkeep without money? whats your point

[@FlippinFruitFly]

This is going to be a good one for sure. What I respect most about Bryan is his openness and sense of humor while putting his body through an extreme kind of experiment and without being too pushy about anything.

[@tominieminen66]

At the same time his life is the least extreme and the most extreme 😂

[@Karl_Smink]

His method is too expensive for anyone outside his earning class, and he's not making money on it. There's no reason for him to be pushy.

[@Cora-wh1rr]

I think the fact that he isn't pushy was why by the end I could in some ways respect his reasoning. The amount of times he just simply said "that is correct" to one of Dr.Mike's arguments was refreshing.

[@voiceanddrum]

Honestly, Bryan’s don’t die philosophy nudged me enough to get in for my regular checkups which I had procrastinated during covid. It’s nice to contemplate a hopeful future for a change. Not everyone will use these ideas to experiment wildly or without their own approach to measurement. Some will just sleep more, eat better, exercise and go for suggested screenings.

[@dinomiles7999]

Glade your AWAKE !❤

[@kevinbing730]

I am shocked at what a talented interviewer Dr Mike is. New Yorkers are not afraid to ask you hard questions to your face :)

[@joemama8243]

those were not hard lol they were all answered and debunked easily, the doctor just wants more patients lol so he wants people to live unhealthy

[@argoneonoble]

I thought Dr Mike is Canadian.

[@beckbeck1432]

@@argoneonoblehe’s actually originally from Russia.

[@rachana777]

A Russian New Yorker at that !

[@Artaxerxes.]

​@@argoneonoble he Russian, lil f*ck

[@Jake-im8eq]

I don’t understand they hate this guy gets for wanting to live longer. Everything he said made perfect sense and he seems like he has put a ton of thought into existence as a whole

[@Bee_Healthier]

It's because it's an act to sell more products that he's partnered with. Welcome to the world, they don't give a fk about you but want all your hard earned money

[@zenzen4982]

There was an older comment that kinda answers this: """ A part of the debate around this guy's lifestyle that doesn't get discussed enough is his unique situation to do all this. And I don't mean just the fact he can afford it, which he does talk about. I mean that he had the time in his day, this is basically his job at this point. So he's less having to trade his free time for his health and longevity dedication like most of us would. He gets to still have free time for things he enjoys like family. This changes the quality vs quantity debate quite a lot. """ My personal take: It is admirable that he does something to advance the species, at the same time it highlights how enormously unacceptable it has become to be poor. Charlie Chaplin said something along the the lines: "As long as tyrants still die there is hope.". It is a lot easier to accept that most people never get to live their dreams, that competition for the sake of competition in a capitalistic system is moot, as long as we share the same fate. He is a trailblazer and I think the hate is motivated by people that would love to explore with him, but society isn't set up for this currently. Even he has to treat this as a business as no-one can predict how long modern slavery will continue.

[@peterhel1077]

​@zenzen4982 he said multiple times that 80% of results come for free. Cutting nonsense food out, sleeping well etc..

[@zenzen4982]

@@peterhel1077 yeah, sleeping well doesn't come for free through. If you are crammed into a slum and the only way out is work that will destroy your body, so you really gotta pick your poison, because your mentally ill single parent left you nothing but debt and ruined your education. 1/7 children in Japan live below the poverty line and that is a society with relatively little inequality. Again, personally I think it is good that someone is doing what he does, highlighting the inequality in society comes with the territory and the hate he gets is misplaced, but will hopefully lead to having the grossest inequalities reexamined. I just image that is the reason for the hate, personally I haven't seen much of it, might be best to ask the people infuriated?

[@user-rawe]

​@@zenzen4982 truth is it will never be possible for everybody, certain jobs have exposure to certain things that he himself needs to avoid to achieve what he's trying to achieve, it would take insane amounts of resources and will power to make it so that those certain things he tries to avoid such as bad air quality are avoided by everybody

[@rksacademybangla]

This is what a conversation between a doctor and an engineer looks like. Both are intellectually sound, yet their logical reasoning skills were built through different mediums of knowledge. Love this episode!!!

[@joannas2533]

Well said!

[@Meneya]

i don’t think he’s an engineer

[@joannas2533]

@@Meneya probably meant software engineer / computer scientist based on his prior companies

[@paulbarclay4114]

yes its interesting to see someone who was trained in "medical" "science" attempt to reconcicle that with evidence based medicine and logical thinking just shows you how backwards "modern" "medicine" is

[@alexv5581]

Engineer lol ? No.

[@jessandrews9576]

To all Podcasters! its ok to be quiet! I love the short silences between questions, it really creates a sense of professionals considering their answers carefully, giving us as listeners a short period to consider our own answers! This is an example of a perfect podcast! so good! two very different professionals being utterly considerate of each others views and Dr.Mike, your questioning was beautiful!

[@SilverFlame819]

I think early KZbin days got everyone into jump cuts, and the short video format followed, and now so much content is exhausting. You have to pause or rewind just to have time to take in what you've seen or heard. It's ridiculous.

[@xtiebro]

@@SilverFlame819this makes me feel better about how often I pause or rewind content... was thinking something was slow with me!

[@SilverFlame819]

@@xtiebro They are often just trying to answer quickly, and viewers want that fast, snappy feel... but how much of it are people really taking in and ruminating on when they consume content that quickly?

[@Eric3Frog]

Silence is just as important as sound. This is true in all conversations and relationships. It gives time to process and creates differential, which are both valuable.

[@HaraldEngels]

I have watched multiple interviews with Bryan Johnson. This was one of the best, it was conducted in a great pace and with questions which really made sense. And Bryan Johnson is a pleasure to speak with I guess. If his clarity of mind is a mirror of his physical health then he is a goalpost for what we all should try to achieve - especially on the philosophical level.

[@katnbud]

I was the person who asked for this video in a comment on another episode of The Checkup! Thanks Dr. Mike! 😊

[@LaurelKeiffer]

He is very interesting and seems super intelligent, however I do feel like quality of life has to be taken into account more. But I love how when he is asked a question, he actually thinks about it. So many people that are interviewed or have conversations rush to push their narrative or defend their thought process, but he seems to really consider, think, and then decide how he really feels about the question posed before answering.

[@skyw8248]

From my personal experience the more I incorporate his methods in my behaviour the happier I am. The more full my life seems.

[@keepernod2888]

How do you define and measure quality of life? According to WHO it's : "an individual's perception"

[@LaurelKeiffer]

@@keepernod2888 I mean, he seems happy so he is getting quality of life. Quality of life is individual I think. I kind of stated short without saying much about it, but he seems like a person that enjoys experimenting, being innovative and working towards goals. He also has a ton of money so he is able to use a lot of time focusing on that. I guess my thought process was that the average person, working full time, spending all additional time focusing on things to “live forever” may interfere with other pieces of happiness such as family time, friend time, alone time, activities, whatever it may be. And again, that’s generalized, there are lots of variables to what would make someone happy in life. 🤷‍♀️

[@keepernod2888]

@@LaurelKeifferI agree with you on that point. I just think that the real reason for his pause was that the happiness and quality of life are very subjective concepts. While they are part of the mental health, I wonder if we should exclude them when we are talking about the health of the body?

[@sebastianheine378]

This guy has little to no understand of the deteriorating of quality of life as we age. Anyone who has worked in the hospital understand this reality

[@essendossev362]

I'm really blown away by how you're such a good interviewer. You're researched, knowledgeable, sensitive, have your own valuable background to bring to the conversation, and so competent at formulating your thoughts and questions into accessible, understandable, and still precise language.

[@TeslaSpaceXX]

Doctor Mike paints Bryan as a wacko with the intro and when speaking to other KZbinrs. Ego has taken over. He is going after Money from my perspective. Not ver doctor like.

[@jooolius]

​@@TeslaSpaceXXdid you watch the video bucko?

[@oscartejada9498]

@@TeslaSpaceXXbrother is just wrong. That’s not at all what happened throughout this video.

[@TeslaSpaceXX]

@@jooolius sure did buckaroo, interview was sightly better than the “click bait eye popping OMG Bryan is a Crazy” photo. Mike is just like other KZbinrs. All about the clicks.

[@thatdaniperson]

@@TeslaSpaceXXyou just invented a false narrative to align with your beliefs about youtubers. delusional

[@alansnyder8448]

I am 100% with Bryan on the importance of sleep, and I have used my Whoop strap to figure out what things affect my sleep. I'm still working on improvements.

[@user-kj2gf1cn1p]

dude, you're an awesome interviewer. you listen closely, let them speak their entire thoughts out, and ask provoking questions without bias. i really appreciate this kind of stuff.

[@marybell8995]

Mike with all the disinformation out there it is a breath of fresh air to have somebody like you on the Internet trying to help people be educated. Thank you so much.

[@sgsgbaegbdfb6416]

oh man the lack of a comma after "Mike" really tripped me up a little bit 😅😄

[@tani4487]

@@sgsgbaegbdfb6416 True 💀💀

[@DrAndrewSteele]

Agreed! It’s a real shame that longevity science has become so closely associated with tech billionaires wanting to live forever because there’s genuinely exciting science going on that could help far more than the ultra-wealthy…

[@marybell8995]

@@sgsgbaegbdfb6416 sorry ‘bout that 😂

[@user-hq4vj3go7b]

​@@sgsgbaegbdfb6416It reads just fine without the comma. Perhaps you talk slow in real life.

[@jmd1980]

A part of the debate around this guy's lifestyle that doesn't get discussed enough is his unique situation to do all this. And I don't mean just the fact he can afford it, which he does talk about. I mean that he had the time in his day, this is basically his job at this point. So he's less having to trade his free time for his health and longevity dedication like most of us would. He gets to still have free time for things he enjoys like family. This changes the quality vs quantity debate quite a lot.

[@xpaperxcutx4588]

He’s spending the money on the testing so that the average layman doesn’t need to. His recipe meals and certain supplements are affordable. The only expensive thing are the biomarker testing

[@MNP208]

Is he selling any snake oil? This is where I draw the line. Supplements are not proven to be effective for people who are not lacking that particular vitamin in the first place.

[@LyrixNChill]

​@@MNP208he was literally selling snake oil yesterday 😂 (April 1st)

[@SarcasticData]

@@MNP208 Yes. I am sure that I'm not shocking anyone by letting you know he sells his own special blend of olive oil and chocolate, as well as supplements because of course he sells supplements. But remember it's for the future of the human species 🙄

[@NootropicWriter]

@@SarcasticDatahis stuff is basically break even. He already made a ton of money, stop being so skeptical

[@olandsmith2660]

That question about the value of life being less valuable when adjusted to be longer was such a great point.

[@BiggieChungulus]

So wait, someone who lives a short life dies earlier than someone who lives longer... The person who lives longer gets more value out of their life by living beceause the person who died earlier is already dead?

[@saurabhsonic]

The other way of looking at the value of life is to compare life lengths --- if you had the choice of two life lengths - one much longer and one much shorter - would you (or anyone) choose the much shorter lifespan because its shorter length implies that it's more valuable? Let me give you my answer: I would choose the longer life every day and twice on Sundays.

[@olandsmith2660]

@@saurabhsonic Just seems that knowing how long on average we live; would make human beings push for more in life and innovation increases. Remember that although you may live longer not everyone around you will…which is sad because eventually you would continually be hurt by all the people you will eventually have to miss.

[@challengerjakku1943]

The question becomes value to who? Value is ultimately subjective, so for Bryan I would assume not dying is more valuable to him. If this man figures out immortality, sign me tf up.

[@Brian-oz8io]

This particular ideology is dependent on technology changing everything and stopping aging and eventually solving most (or all) of our problems. If we hypothetically assume that to be the case, the idea would be that if you live long enough you’ll get to experience completely new things that haven’t yet been thought of. You might also get to do all the things you want to do now (that you feel might increase your quality of life) and more For example: If we had complete control over our biology in the future, you might get to eat all those potato chips or whatever else you wanted to do and it wouldn’t matter anymore. So the quality of life you have now wouldn’t seem like a big deal. If you lived 500 years, you’d probably look back and say “wow the first 40 years of my life weren’t exactly what I wanted, but these last 300 have been awesome.” This part of your life would probably seem like less than a prologue For some people, I guess those possibilities are worth making some sacrifices

[@jaymills1111]

You're legitimately one of the best interviewers I've seen, and this was super interesting. I particularly like the way you asked Brian questions and I really enjoyed the way he answered them and thought about them. Great discussion, please for the love of all things keep interviewing people!

[@grumpyhawk509]

For the love of God you mean? Or don't believe in God?

[@SuUltimoPacto]

@@grumpyhawk509 She meant “all things” in other words “don’t stop interviewing people for the love you have for life!” As much as he loves life, that’s how much he should interview others. 👍🏼

[@vdp888]

It's because he's a family medicine doctors. Unlike majority of specialities he has to take time (although limited) to listen to his patients to help treat them. Most important test is the the history and physical! ❤

[@susanmirabi3565]

This was an unexpectedly thoughtful conversation with a man who has undoubtedly made a splash in the headlines for being seemingly eccentric in his quest for youth. He came across as much more self aware than I would've expected. Thoroughly enjoyed this one!

[@kingcosworth2643]

The idea of living forever sounds like hell, no thanks

[@VirusTree1000.]

​@@kingcosworth2643 You don't have to do it, but I bet your tone would change when you're finally decaying at a nursing home.

[@joshwadsworth8261]

I also was not expecting him to be as self aware as he appeared to be during this interview. I enjoyed it.

[@DemsW]

​@@kingcosworth2643the best thing is having a choice how much time you spend there. Most people that die would probably wish to have been younger longer.

[@v4ln]

@@kingcosworth2643the idea is not necessarily living forever, but living until you choose not to, or, not dying when you want to live

[@jamesthefirst_8147]

what an absolute masterclass on both ends. The right questions were asked by Dr.Mike and Bryan was open. Both discussing the subject calmly while putting their opinions/experiences on the table in a transparent way, even if they colide at times. Another great interview from Dr.Mike

[@jozefwoo8079]

Second conversation I watch on this channel and now I understand why it has so many subscribers. What a respectful and yet thorough conversation! Well done.

[@ItzEpix]

As a person who is 9173 years old I can confirm this video is real

[@everlyneawino1769]

Oh ok😅

[@nicholaswilliams3133]

I can confirm it is real too im 6969 years old

[@mohammedezzinehaddady7252]

I thought i was the only one, i think i am gone throw a birthday party the next month i should be 10k by then hopefully 🥸

[@esejoshsantana2271]

Im pretty sure this video is true im 4115 years old and i eat 98% of hes diet 🤔

[@azpont7275]

Long live the Emperor!

[@JayasuryaParthiban]

The way you sculptured the questions for Bryan is mindblowing. I can literally see the kind of preparation you did before interviewing him on your podcast. Big fan of your work on KZbin, Doctor Mike!

[@TeslaSpaceXX]

Doctor Mike paints Bryan as a wacko with the intro and when speaking to other KZbinrs. Ego has taken over. He is going after Money from my perspective. Not ver doctor like.

[@dennylekstrom4517]

Hands down the most exciting interview and topic I've seen. The approach to arguments, listening and answering, the knowledge and understanding and respect. Notice how when doctor Mike makes the argument about "don't die" possibly coyld be the same thing but from the other end of the spectrum the reply is "Yes. So I try my hardest to prove myself wrong." or along those lines. Makes me so happy!! And I'm only 10 minutes in. I have to sleep 😂

[@coocat231]

Perfect conversation between a scientist and an engineer. This needs to happen significantly more. This is how innovation and advancement happens.

[@ItsJennNotJenny]

I absolutely love how empathetic, well thought out and understanding Doctor Mike is. Even if he isn't agreeing with someone, he's not condescending, rude or antagonistic, which is something we need more of these days. The best way to understand something/someone is to communicate and remove ego. There's too many great interviews on this channel to count! I'm a rare disease and multiple rare condition warrior who has lived a very different life than most, and your channel led me to become aquiantences with Bea. She understands more than most people I've known what it's like to be a medically complex person and be judged for superficial and difficult life situations by ignorance. Keep being awesome ❤ I truly hope to have you on my podcast someday!

[@mitalishinde6890]

Right I really admire that!

[@sophiemarlonansems]

What’s your podcast called?

[@ItsJennNotJenny]

@sophiemarlonansems it's called "Seriously Random." It's new and not released yet as I'm still recording and editing, but keep an eye out for it on KZbin, Spotify, and Apple. 🙂

[@Anna-ms1pd]

Dr Mike for president!

[@TeslaSpaceXX]

Doctor Mike paints Bryan as a wacko with the intro and when speaking to other KZbinrs. Ego has taken over. He is going after Money from my perspective. Not very doctor like.

[@ElderBobcat]

So he’s recognized that he’s in a unique position where he has the ability to focus on future ideology and sees while this may not make him live forever it’s somewhat neutral positive for his health and simultaneously influencing future researchers to pick up the mantle. Gotta say he’s not as crazy as i thought from media

[@MsFanpireProductions]

Shows how the media sensationalise things

[@e7193]

just look at his face. you’re seriously calling that neutral positive ?

[@ElderBobcat]

@@e7193 if you want a real response I believe he’s taking some derivative of estrogen that has caused his skin to be somewhat smoother without the feminizing effects. As I said hes the guinea pig for future generations to go that worked, that didn’t. And progress from there

[@bperez8656]

You shouldn’t have been listening to the media in the first place

[@Vastilious]

​whats wrong with his face ??? He just has glass skin @e7193

[@jonnypeters0]

This checked all of the boxes of a great interview. Listening, prompting interesting and relevant conversation, providing valuable and educated criticism, adapting the questions to fit the tone, giving disclaimers when something moves into opinion territory. Submit it as material for college courses on interviewing.

[@J.Colfer]

I swear my brain grew bigger after listening this conversation. Impossible “listen to it in the background”, requires all the attention to understand this deep conversation. Loved every second of it!

[@Noctua07]

You should see a doctor to make sure the swelling doesn't cause brain damage ;) :P

[@Bela363]

"Don't die" puts me on alert. Live! Gives me strength.

[@markmits9075]

I think he might be expressing that on purpose, to try and fight common unhealthy things people do.

[@theanarchonazbolinquisition]

Being alert increases your chances of staying alive though.

[@decoy8198]

You have spent all of the last 20 days living, how many have you spent not dying. Worth thinking about

[@Bela363]

@@decoy8198 It's a question of perspective. Words have power. This is called positive psychology. Using words like “death” increases my stress level and therefore my range of thinking. Those who fight with a cool head fight better and are not cramped like he is. Better to climb upwards in life than to only hold on before death. Do you feel the emotional difference when you read this?

[@Plamler]

If a human’s goal is to reproduce prior to death, in a post- death society the core instinct would be to not die because the opportunity for reproduction is always available. Just on a logical sense I kinda get it.

[@jplayzow]

I appreciate no matter right or wrong he hasn't deluded himself into thinking he has all the answers and knows immediately what will happen

[@danielgriffiths5901]

Yeah, both were really sharp here

[@joanasilva8610]

Great great interview, Dr Mike! Great questions and also great answers. I loved Bryan's way of thinking and how honest he is about what he is doing. I'm with Dr Mike. I still have strong doubts about Bryan's process, but it still opened my eyes. Thank you for this episode. :)

[@JamalIssa]

such a respectful, calm, and insightful conversation. this is how debate and modern-day conversations should be about, regardless of topic.

[@ronjakh]

I have so much respect for Bryan! He’s not gatekeeping anything and I truly believe that he’s going to make a difference. He’s also so empathetic and understanding of people who aren’t able to do what he’s doing. He doesn’t expect anyone to walk his path, he doesn’t shame anyone for making “wrong” choices and shares what’s most effective according to the research so we can adapt it to our own lives. He’s basically surrendering his body and life to the research and furthering what we know about longevity. I love watching his videos, fascinating!

[@OArchivesX]

Lmao he has a cult following and literally just pushes pseudoscience on his channel, and just tells people to "work out and eat healthy".. Bryan johnson followers are just cringe.

[@etz8360]

@@OArchivesXwhat is this "psuedoscience" you speak of?

[@Real28]

He is not empathetic at all. Dudes doing what only 0.001% of the population can and being naive thinking he can live forever. He dies before 100. Watch.

[@NoobieToob]

@@etz8360 pretending his n=1 case study has massive bearings on the wellbeing of humans as a species

[@ronjakh]

@@OArchivesXI’m a casual viewer of his videos and don’t know anything about his “following”. Wouldn’t call myself a follower as such other than being subscribed to his youtube channel. I watch a lot of creators on here for entertainment or interest. as far as I know he only does things that are backed by science and tangible results. No pseudoscience or opinions. If you don’t like him or his way of life, don’t watch his videos and don’t follow his advice. No one is forcing you into anything 🙂

[@TsChryssa]

I admire Bryan Johnson for his innovative spirit and entrepreneurial vision. His ability to merge philosophical and scientific concerns in such ventures showcases his multidimensional approach to problem-solving. Dr. Mike's expertise as a doctor and his pragmatic nature adds depth and perspective to their podcast discussions, making it a valuable and enriching experience. I thoroughly enjoyed the entire video and watched it non-stop!

[@kingcosworth2643]

The concept of living forever might sound great to someone who lives without stress and has the freedom to live the way they want. The idea of me having to work my labour intensive job for eternity sounds like a fate far worse than death, I'll take the death.

[@Dr.Hiccup]

I agree with everything u said but ur comment sounds AI generated lol

[@Stereochemistry]

I find him delusional, abominable, self-absorbed and entirely detached from the reality. Likely the saddest person I've ever seen in my whole life. Yes, he reflects on things but from a perspective of a super rich American capitalist... A perspective that is reserved for the 0.0001% of this planet, entirely unsustainable at any level. Infinite life on a finite planet makes no mathematical sense and no AI will ever fix that paradox

[@francescafrancesca3554]

​@@Dr.Hiccup I know right? I thought the same thing JAJ

[@Stereochemistry]

@@neovyk I'm definitely not miserable. I just find that he's entirely detached from reality. His mission and belief is to advance the human race by doing a single person experiment. A single person experiment that costs millions will do nothing to advance the human race as such, when the majority of that race lives in poverty lacking basic stuff. Very, very few people have access to that level of care that he's using for his experiment. Moreover, thinking that the outcomes of a single case study can be generalised and considered valid for the entire population is flawed and goes against the very core of that science that he claims he understands and uses to his benefit. And ultimately - longevity is overrated. It really really is.

[@zhangir40]

I didn’t how much I needed this podcast because in most cases I see videos with Bryan Johnson as rich man with some cool slash weird gimmick while this podcast actually deeply shows he is thoughts process rather simply saying I want live longer.

[@esaef91]

2 intelligent people with different viewpoints having a civil discussion. I love your podcast.

[@VRayDantesTrygorn]

I loved that Bryan actually stopped to think about answers. This was a brilliant conversation between two very smart human beings. Loved it ❤

[@yajurvendrachudasama7497]

I like the way this Bryan Johnson talks. The way he’s thinking before answering questions.

[@OArchivesX]

Yeah because he's trying to bullshit his way through unanswerable questions... Watch his channel and see the garbage set up to appeal to his cult following loll...

[@MusoStuu]

One of the most thought-provoking interesting debates I’ve heard for ages, I was glued for the entire time.. he’s actually quite a philosopher..❤

[@kartezhnay]

G, doctor Mike is on fire 🔥🔥🔥 I absolutely loved that interview, what a great questions, finally someone is challenging Bryan believes. I also applaud Bryan’s ability to explain his prospective without being too defensive or aggressive. Great conversation!

[@fantastichan]

Don't get why some people say the interviewer is being condescending. Just because he's asking pointed questions and challenging the believes doesn't mean it can't be done respectfully. People nowadays are so fragile. Also very impressed with how the answers are provided. Always taking time to think and answering straight to the point and with careful consideration. And he's very self aware.

[@e7193]

“people nowadays are so fragile” is such a cop out. people have always been fragile. you’re just feeding into the long held belief that the loud minority is actually the majority

[@bperez8656]

Dr. mike is a hater vying for gotcha moments Big pharma spokesperson trying to take down independent people and free thinkers who are engaged in research outside of big medicine.

[@Antifuzz1]

I have seen this a lot online, could potentially be a lot of people who speak English as a second language and or don't understand the complexity of the conversation/ don't understand the nuances of asking a complex question holistically not because the person asking the question has that stance but to test ideas.

[@Appp21]

The questions that Doctor Mike asks is always very deep. It is never boring or straightforward

[@tatyanasever77]

I'm so impressed by Mikhail, you are such a beautiful interviewer. It was so nice to spend this time by listening this conversation. Thank you ❤

[@OscarGarcia-fe5bu]

Great questions, answers, and opinions. Amazing interview! Wish more interviews were like this.

[@Rodrigo_Goes]

I like Bryan! He’s doing an amazing experiment, truly valuable to science 🙏🏻

[@matheusulisses5579]

Well. Look at him!

[@matheusulisses5579]

Is Bryan Fake Natty? 🧐

[@namelesswonder7077]

@@matheusulisses5579 I don't think there is a point in asking Bryan "natty or not" for what he does. He definitely optimizes his hormonal health which might result in him taking HRT.

[@pibs863]

imagine what can bryan's baseball bat do

[@matheusulisses5579]

@@namelesswonder7077 You're right. But what I said was a joke that you wouldn't understand 😌

[@willlagos8554]

I really appreciate Bryan’s earnest thoughtfulness - his ability to consider questions, his own experience, and his admission when he doesn’t know or hasn’t considered something. And the questions that provoke this sort of thought. Great conversation between two very thoughtful humans. Great video.

[@bangturden7070]

i could listen to you two for three more hours and would not be bored. great conversation!

[@marcusbrown3062]

I always love watching these podcast episodes with these different scientists, healthcare professionals, and researchers because there is always such interesting and thought provoking discourse taking place in a respectful manner

[@AwakenYourSensory]

This pod hosted by Dr. Mike and Bryan Johnson provide valuable insights. My key takeaway is the importance of adopting a lifestyle that prioritizes the quality of life. This involves focusing on aspects such as improved nutrition, regular exercise, sufficient sleep, overall mental and emotional well-being, and allowing other uncertainties to resolve themselves. Additionally, it's essential to embrace the mantra of living, loving, and laughing along the way.

[@HeidiDressler]

As an RN who has spent most of my career caring for the elderly and whose father passed away recently with dementia. I think dying teaches us about life, You learn to appreciate that you only have a limited time with the people you love, so you make the best of your life and the time you have together.

[@dannybolduc7109]

At the same time, many people live their whole lives before truly realizing you get one. An unfortunate fact.

[@joannas2533]

Very sorry for your loss 🙏

[@HeidiDressler]

Thank you, I really appreciate your kind words.

[@SchopenhauerVsCamus]

It’s not easy losing loved ones. Truly sorry for your loss… In a world where lifespans can be extended indefinitely, Radical Life Extension (RLE) should not exist without the global right to exit existence in a peaceful, guaranteed and humane manner, at a time of one’s choosing. As Radical Life Extension (RLE) becomes available, some individuals might wish to continue living indefinitely-and that’s fine-while others will not want to do that, for a wide range of reasons, depending on their unique circumstances.

[@sometimeslifehandsyouapple1085]

I am also reminded that suffering and death are the engine behind so many works of art across many genres. These things challenge us in many ways.

[@huckwalton2307]

I really admire the way he stops and considers each question. It makes me trust his pursuits and his intelligence.

[@Zack_Taylor]

Only ten minutes in but I do respect this guy more than I thought I was going to. I don't necessarily agree with him on everything but he's a lot less arrogant than I was expecting him to be.

[@yanille4109]

This was a great interview man, im fairly new to your channel and can see why you're as successful as you are, thanks for putting stuff like this out there.

[@Joe_SharkSkin]

Remember, longevity starts now! People always make the common mistake of worrying about wear and tear when it’s too late, I.e. blasting music in your ear and now you are going deaf and want treatment! Treatment starts now! Practice preventative measures now! NOW!!!

[@nicbarth3838]

This is true thanks for the inspiration

[@martaribeiro96]

For real. I started changing my lifetsyle a little bit (emphasis on A LITTLE BIT) and I was seen as crazy because I was too young to worry about those things. Like, yeah, sorry I'm trying to prevent future health problems, I really must be crazy 🙄

[@Havok135]

Mmm fear mongering, gotta love it.

[@PS-lv1mr]

wear earplugs in concerts. they make great fidelity earplugs that make it so it essentially reduces outside volume but retains audio quality

[@MsFanpireProductions]

@@martaribeiro96what stuff did you change?

[@gillesh.9405]

Thanks to both for this video. I enjoy it deeply. I stumbled upon Bryan through diary of a CEO and find him fascinating. I disregard all the hate he gets, I see in him a truly generous and dedicated person that wants to achieve a goal and he is not hurting ANYONE by doing so. I enjoy Mike’s approach to this discussion and it was a genuine moment with good questions. Great content

[@Planetside223]

Could have donated that money to a childerns hospital. I wouldn’t really call this generous, just someone afraid of death with a large PR budget

[@eduardobreda1279]

@@Planetside223go make that kind of request from your politicians mate.

[@skyw8248]

@@Planetside223you can donate all your money to a child’s hospital. You aren’t even investing your money into various longevity technologies.

[@14s0cc3r14]

@@eduardobreda1279por que no los dos?

[@RandomSourceOfAllCrabBeing]

I think something like this at some point of the interview but he also say that he's gonna put all the information gathered of his proyect for free and who knows maybe between all that we find some few things that could benefit medical advancement (not necessarily human inmortality but in other kind of stuff). ​@@Planetside223

[@marvanbee]

I would love to see Bryan's work expand to mental health and trauma. I think there is sooooo much humans have to cope with that negatively impacts their health, literally impacting things like immune response, breathing, etc. and to the best of my knowledge, nobody is bridging the gap here either. I would especially like to see this with children/people who grow up in the foster care or group home situations; a massive percentage of these people end up living on the streets and having severe addictions at frighteningly young ages. Nobody can simply just tell those people to sleep more or eat better; the absence of parental and societal love has deep, deep impacts. Imagine somebody could say, "so, you went through [insert trauma here], which resulted in x and *this is how we fix that* "! So few people have access to affordable, quality therapy that supports not only the mental & emotional well being but also tracks things physically to determine physical effects. Healthcare is still far too much of a piecemeal model with specialists not talking to one another and the patient kept largely out of the loop. Maybe one day Bryan will be minister of Health in some part of the world. I wonder what he'd do in a role like that. Anyway, lovely and intriguing interview. :)

[@Jade-ms2ys]

perhaps dr Gabor mate would interest you on this subject

[@marvanbee]

@Jade-ms2ys thanks. I've listened to bunch of his talks and he seems to also lack scientific tracking of physical changes with treatment. And not all treatments are effective for all issues. Hopefully we're heading in the right direction though.

[@Axonnnnn]

a doctor is required to have the quality of taking care of people /the considerations about them /which dr mike reflects on in each videos is a nice ,encouraging,realisation which i finally got from your videos .THANKS

[@StudioKujira]

Such a great listen. Mike is a terrific interviewer and Byran was a terrific guest.

[@HFXmermaid]

I'd love you to interview the Blue Zone's guy, Dan Beuttner. He's a natgeo explorer who researches centurions and "Blue Zones" places around the world and studies the commonalities in populations where most live healthy into 90s and 100s. He really pushes more specifics when it comes to diet and exercise etc. There's a Netflix doc series about it and he has several books. I read them and they seem like sound science, and he's backed by NatGEO. But I'd love to see him chat with Dr. Mike!!

[@epicipodmodz]

Damnnn you got a like!!

[@richardgabbrielli3328]

You need to research the fraud associated with the blue zones bs...

[@LoveBoundMedia]

So happy you did this podcast. I’ve been waiting on this!

[@AlecSorensen]

Kudos to both of them. I have a rarely seen a video where a person challenges another's ideas so thoroughly, and yet both are respectful.

[@fadedace1342]

YESSS I'VE BEEN LITERALLY WAITING FOR A VIDEO ON THIS. I was sad when I was looking around for an interview and couldn't find one with you and him. SO excited to watch this. Thank you!

[@PrincesaAzalea]

I LOVE how respectful Dr. Mike is. He makes the interview with healthy skepticism but remains open minded at the same time. What an incredible interviewer. Thank you for this, I truly appreciate it.

[@blanche.o]

Such an incredibly respectful and information rich interview. I can totally relate from 49:46 regarding not wanting a “cheat day”. I know that drinking red wine makes me feel like trash and I can’t sleep at all, where a glass of white at dinner occasionally doesn’t affect me. I know that eating any fast food, deep fried things, sugar, large amounts of bread and dairy, messes with my tummy and make me feel bloated, nauseous and just groggy for at least 3 days. I know that eating a lot of vegetables, certain fruits and lean proteins energize me and help with good sleep. I know that fasting 1-2 days of the week is good for me, not only for religious reasons but also because I feel rejuvenated, more productive and can focus my attention on other important things such as work, praying and spending time with loved ones. So why on earth would I put myself through the pain of having a MacDonalds burger and fries, or a Domino’s pizza, or a glass of red wine at dinner when 1) they don’t even taste very great and 2) I know exactly what I’m getting myself into.

[@ninakoch1799]

Great interview, both speakers are clearly very intelligent and respectful. I might not agree with everything Bryan is saying, but I respect his vision and I think he‘s doing us all a favour by making his statistics and visions public. Thank you both for your insights❤

[@nolaquev]

I love Bryan. I really admire his discipline and how he's thought through his whole philosophy. Good to see Dr Mike listening so closely with an open mind.

[@nijiayame848]

I came here as a skeptical (even biased) but this whole postcast was so mindblowing and eyes opening - I cannot thank both of you enough.

[@jan_schaefer]

genuinly love this episode. The conversation is so calming to listen to because both participants think in depth about what they're saying/asking. Both answer in they're own way of thinking and perception without being biased and subjective about things. I'd listen to hundreds of hours of this!

[@jan_schaefer]

Edit: Not completely unbiased, but well reflective of their biases 'caused by their different jobs/education!

[@deeal]

I really like you Dr Mike. You cut through the noise with so much finesse

[@user-tc3iv2fe1d]

Dr. Mike is my favorite content creator. I have enjoyed every video I have seen by him. He brings up topics that make you think and increase your medical knowledge. I love how respectful he is to everyone. And I love how he reminds me of my baby brother. They have similar features, so he feels like another baby brother to me who is teaching me instead of the other way around. Keeping doing what you do, Dr Mike.

[@gharris2119]

This was such a thought provoking conversations. It is interesting to see from multiple perspectives the idea of death versus quality of life as well as views towards death. You did such a great job Dr.Mike with such great question. It was a wonderful podcast episode!

[@killerfrost7904]

I could've watched this podcast all day🙌🏻. Great questions and very reasonable answers.I just love it❤

[@coocat231]

VERY well thought out interview and responses both with very respectful approaches. This was one of the interviews from doctor mike that I really thought was integral in helping the average person dissect these topics. 😊

[@TheUnofficialBoss]

I love how respectful and calm these podcasts are, especially if really great questions and insightful answers given. Even if everything is based on opinion, it's still so interesting to listen.

[@Studycase3000]

This was SUCH an interesting conversation. Bryan Johnson is a futurist, through and through. Once I thought about it (took me 2 days to hit play) and gave the vid it's chance, I was completely engrossed within the first 3 minutes. This was one of the fastest hour long pods I've sat to watch. Thank you both for being open and candid on THE eternal hot topic

[@eatmyspam]

I love Dr. Mike's scientifically astute observations on the public's interpretation of scientific data/"voices" and problems with methodology. This is so useful.

[@vitorhugo4547]

What an amazing interview! Great work doctor Mike!

[@v-22]

Honestly, I do not understand people who would want to know when they would die. It's like living every second of your life with a ticking time bomb.

[@sararistow6137]

We know it’s a time bomb- it’s just a matter of knowing the time or not. We all know how it ends. I’d be interested to know when I would die. Instead, I choose to act like this is the last decade. Last year is too short, but planning for a decade is reasonable and I have faced my worst fears because I pretend it’s ending very soon comparatively.

[@Thrive_Momentum]

I finally understand what Bryan Johnson is doing, thank you Dr. Mike for helping us see a better side of his view

[@davidholm4999]

I think it's a mistake to look at him as some kinda role model. He's a science experiment, and you gotta respect his dedication. A lot of what he does has potential to really help us.

[@FenrisZAmarok]

Agreed. It sounds like he does a lot of good, but he’s not really saying or doing anything groundbreaking. The idea he presented in this interview is “someone eventually will invent super intelligent ai and well live forever. I don’t know how, but someone probably will and I won’t have to die ever.”

[@lilium_lancifolium]

Not really. There's absolutely nothing we can learn from him, because he does so many things to live for such a long time that we will never know what actually works.

[@arnavrawat9864]

He can be both of those things. I think Bryan is a role model of dedication to the fundamentals of our lives which we let run away from us for pleasure pr ego

[@davidholm4999]

@@lilium_lancifolium That's just not true. He's being monitored closely by professionals. I'm sure they have a pretty good understanding of what's working or not.

[@hiskishow]

Exactly what Lilium said. Almost nothing to be learned also since what he is doing is trying things that are already in research. The actual research takes hundreds and even thousands of people to figure out if it has a positive correlation to the lifespan and quality. For example even though there is so much research on the heart medicines of today, still doing meta research on the hundreds of studies reveals that it is not so cut and dry if they are good or not. Doing research on one single person is for nothing, when research done on hundreds of thousands if millions of people has difficulty revealing the truth. Not to say he can't prove it for himself. That he can do but to say it will work for everyone is pretty ballsy.

[@itswhzly]

I love how Brian really takes time to think, he's so authentic and intentional, I dont see an ego behind his eyes just waiting to counter, he's great

[@Doomsdaymanx]

I love how Dr. Mike handles being an interviewer. He's open to his guest's perspectives, really examines their arguments, asks probing questions, and doesn't let the conversation get too derailed if his guests subconsciously fallback on the same tired script because he's identified a point they don't have a good argument against. It leads to such interesting conversations, and I always feel like I better understand his guests perspectives, even though I still might not agree with them.

[@Merperson2222]

Probably the best Bryan Johnson interview out there! Thanks Dr, Mike for this great interview!

[@lauragamello560]

I am so impressed by this interview. Both men are extremely intelligent and able to have a conversation delving in to the whys, whats, whens, and hows. Not always agreeing upon everything, but being absolutely respectful and listening intently and understanding the other’s opinion, with what seemed to be great respect. I honestly find this whole exchange fascinating. Although I do have a lot of the same questions, doubts, and concerns as Dr. Mike, I found myself also understanding Bryan’s take on certain ideas and concepts. This is his experience and his reality and he is certainly not an ignorant man. Brilliant interview, gentlemen. 👍

[@KyleHohn]

Beautifully done podcast! Dr. Mike is a master of his craft.

[@Monxtv]

Loooooved the way you managed the interview, it actually gave me so much peace to see two contradictory views on everything.

[@Delphisun1]

This is probably the best interview done with Bryan Johnson. Very happy you did this interview

[@jovial-coach-65]

I was excited for this podcast and for my surprise i wasn't disappointed at all, love dr mike and bryan for there efforts towards society and to make it a better place for all of us❤

[@joaomatos8286]

It was great to hear your debate, would love ofc to hear something more in depth but yhea, thanks for this interview!

[@nate9776]

I loved this conversation! You challenged Brian, he was thoughtful in his responses, just a great watch overall.

[@NicoleDaKiwi]

I really ❤ this interview. Two intelligent people from different backgrounds discussing their perspectives without preaching. Mike, your open-minded approach, your thoughtfulness of listening and asking intelligent questions based on his answers instead of relying on a script was refreshing.

[@mogwai_]

Doctor Mike is becoming my favorite content creator. Love these podcasts

[@infinitedeath1384]

He's definitely my favourite content creator about medical stuff.

[@robbie_stevens_]

Wow, Mike! I really appreciate this conversation. I'll admit, I have come across your videos before where you go against biohacking etc. and my bias was always to not like these videos. But this conversation was incredibly nuanced, and I apologise for my misconception about your videos before. There are some really great points on both sides, especially on the actions we can take. Thank you very much!

[@space_time_everything_else]

Came here wanting to criticise Bryan, left this being a fan of his. Bryan, truly is a great mind and has a ton of knowledge and critical thinking skills. Loved this one!