Click here for the full video: Robert Lustig, MD - Food, Metabolism, and Psychiatric Disease

Robert Lustig, MD. Food, Metabolism, and Psychiatric Disease
Dr. Robert Lustig is a pediatric endocrinologist known for his research on the effects of sugar consumption on health, particularly the relationship between sugar and central nervous system diseases. His thesis suggests that excessive sugar intake, especially fructose, can have adverse effects on the central nervous system. Lustig argues that high sugar consumption can lead to insulin resistance and chronic metabolic diseases, potentially impacting brain function. His presentations and research often focus on the harmful effects of sugar, particularly fructose, on various aspects of health. It's important to note that while there is ongoing debate on this topic, Lustig's work has contributed to discussions on the potential health risks associated with excessive sugar consumption.
About Emery Pharma:
Emery Pharma is deeply committed to advancing public health and exclusively focuses on projects that enhance the well-being of both individuals and the environment. As a comprehensive contract research laboratory, Emery Pharma provides extensive support across the entire spectrum of pharmaceutical development, covering small molecule drugs, biologics, biosimilars, gene therapy, botanicals, and more.
Emery Pharma's array of premium services includes analytical and bioanalytical solutions, microbiology and cell biology services, drug and impurity characterization, and comprehensive R&D with cGMP/GLP support. The Emery Pharma team excels in customizing innovative solutions tailored to the unique requirements of each client. They seamlessly oversee the entire process, from initial drug discovery to thorough data analysis and insights generation. Their expertise allows them to tackle scientific challenges proactively, ensuring clients avoid unnecessary setbacks.
Emery Pharma's accomplished chemists and biologists harness state-of-the-art technology, encompassing cutting-edge tools such as high-resolution mass spectrometry (Orbitrap), triple quad LC-MS/MS, GC-MS, preparative HPLC, and 400 MHz multinuclear NMR.
For further details, please don't hesitate to reach out to Emery Pharma at [e-mail] or explore their website at:
emerypharma.com/

[@drhanafayyad4347]

I love uur talks

[@kimyettamcneal5570]

Dr. Robert Lustig has saved my life and he is saving the world.

[@proudchristian77]

Baby, Lord Jesus gets that title , 👣👑💝💒

[@brucemckay6615]

Might be pushing that one a bit hard…. But he is certainly getting the message out there…

[@kimyettamcneal5570]

Right!🤗 And we need to help spread it to our families, friends and neighbors!!👍🏽

[@kimyettamcneal5570]

Don’t confuse this statement with my faith in God!!😂

[@Kyarrix]

​@@kimyettamcneal5570You don't have to clarify that. What you said the first time is fine. And it's accurate. He's saving lives.

[@keekim59]

My brother was diagnosed with schizophrenia 4 years after moving to USA. Growing up on a completely Asian diet then converting to a standard American diet living in a dorm , feeling homesick and alone didn't help. My mom claimed for years that coca cola gave him the disease. Now science has caught up to her wisdom. He was a concert competitive pianist and brilliant beyond belief, true prodigy.

[@kenadams5504]

Do a keto diet for schizophrenia. Watch Dr Chris Palmer on youtube .

[@kzl7711]

How is he doing now? Is there a cure?

[@maricamaas2326]

Also look into 'Bread Madness'/'Wheat Schitzophrenia

[@maricamaas2326]

​@@kzl7711 Removing toxic, triggering substances is the first step. Fasting is an excellent tool to assist the body to detoxify.

[@aurapopescu1875]

Did he recover?

[@HARRi81_UK]

4 months ago I was diagnosed with type 2 Diabetes. My HbA1c (blood glucose) was 73 mmol/mol. Since then I have moved to a mainly wholefoods diet with little processed food and no UPF. I eat many organic things where possible. I eat strictly pumpernickel for bread, no refined carbs, no potatoes, ZERO added sugar and control carb portions to around 50g per meal. I enjoy cheese, fatty natural yoghurt, whole milk and snack on nuts, which keeps my fat intake at a good level. Kimchi, sauerkraut and yoghurt help my microbiome. I have also done a morning workout (exercise bike and weights) 4-5 times a week and have taken 500mg of Metformin twice a day. In 4 months I have lost 17.5Kg/2St 10lbs/38.5lbs and my blood test results today show a HbA1c of 36mmol/mol, which is amazing!

[@nicolatesla5786]

I'd love to hear more? Sugar gave me depression and anxiety and diabetes plus two or three lost jobs and one divorce. I so much want to sue the food industry ! Can you join the Robert lustig fan group love to talk to you more about the corrupt food industry. I go by lk on the group

[@lahoya32]

Very well done.

[@HARRi81_UK]

@@lahoya32 thanks 👍

[@Ellejano]

Robert Lustig an amazing Genius. The man has knowledge that can actually change the world.

[@drhanafayyad4347]

Every time I listen to dr Lustig I get fascinated further, only to want to hear more of his unmatched scientific n pathophysiolgy knowledge❤

[@drhanafayyad4347]

Would u thus accept the recommendation of taking daily doses of honey?!

[@drhanafayyad4347]

You are a stunning scientist n an eloquent teacher❤. Is there an explanation for the observation( on my side) that when u r accustomed to only glucose sources) ur brain(healthy enough) turns intolerant-n even repellant to sucrose sources. May be it has to do with receptors or hormones?!

[@dashagudym3938]

Dr. Lustig is just awesome. I’m a biochemist and struggle with depression so I enjoyed this one A LOT. Thank you!

[@Mrs.TJTaylor]

Also make sure your vitamin d level approaches the top of the range. For me, that alone rid me of low level chronic depression. Changing to a ketogenic diet then gave me energy and opportunities for happiness. Try for a month and see for yourself. Best to you!

[@dashagudym3938]

@@Mrs.TJTaylor I am in fact deficient in vitamin D. Started taking quite high doses and will see how that went soon. Also attempted keto and realizing how addicted I am to carbs. Scary

[@chrissie.0864]

Best to Vitamin D with Vitamin K2 as K2 facilitates Vitamin D uptake 😀

[@Islamisthecultofsin]

@@dashagudym3938 Throw out the sugar and eat once a day at 3 pm and you will feel better than ever. Meat, mashed potatoes and salad. I even added desert when I lost too much weight.

[@xanthipezembillas8936]

I love Dr. Lustig, he changed my eating life style..3 years carnivore, extremly healthy! my Dr sees my blood work comments excellent health.... see you next year!! i am never sick not even a cold!! Thank you for all you do to change the health care industry! Keep going!! God bless!

[@Kyarrix]

I usually maintain keto close to carnivore. What do you eat? How strict of a carnivore diet do you do? Do you eat eggs, pasture-raised eggs or grass-fed butter or strictly meat and salt?

[@aurapopescu1875]

Same here.

[@debbiebeatty8449]

I have long thought that the brain is part of the body and just as vulnerable to damage from poor diet as the liver, heart, kidneys and gut. Never understood how doctors could claim mental illness had nothing to do with diet.

[@isidorochannel]

I'm also carnivore and I'm happy for you, but you must have found that out by yourself since this man has literally said that our guts want fiber, not to mention other videos where I heard him say that somehow fructose from fruit is not a problem and that he believes the best diet is pescatarian... Goes to show that you can be a good researcher in your narrow area and then completely fail to understand everything else when it's just one step outside. And judging by his looks, he doesn't seem to be following a low-carb diet anyway.

[@1947-]

😊😊

[@odette8905]

He's so right. It's profit before people. We The People must drive this.

[@tartarus216]

Been listening to everything I can find with Dr. Lustig recently and he is both scaring the heck out of me and inspiring me to change my life and diet. Thank you for posting this.

[@drdluv]

Same! Day 12 no added sugar

[@keithsteele1552]

I'm going to need to watch this 5 more times.

[@Emerypharma]

We at Emery also have to watch it a few times!! Extremely educational. Everything connects together 😄

[@odette8905]

Excellent presentation. True that behaviour inattention increasing in schools. School meals have become all fast food, nutritionally poor, ready meals. What effect for the children?

[@Emmuzka]

Twenty years ago, when I was a student, I participated in a study where they observed what happed in the brains of obese adults when they were given fructose-sucrose via IV. The MRI was done three times, with one time being with a placebo. The subjects were also asked to guess when they were given fructose and when not. Yup, I sure did know!

[@Butmunch666]

So...what did happen to the brains of obese adults?

[@virginiahopkins5735]

Dr. Lustig has turned my life around, Stopped eating all foods with High Fructose Corn Syrup. My A1C was 6.2 five months ago. Also stopped all seed oils. 68 years old, With change in diet, I am counting calories, to match my age and highth to loose weight the right way. I have lost 25 pounds, My A1C is now 5.6, My Doctor had talked to me about loosing weight to try keeping from going on another medication.

[@maryl234]

But it's not about calories.

[@blossom7582]

I could listen to this guy all day, he's so brilliant but still makes it understandable for everyone.

[@dennysmith5284]

As always, the simple principle is GIGO: garbage in/garbage out. The only real discussion is what is garbage and what is not (food, diets, behavior, etc...), and Dr. Lustig excels at tying it all together and the picture begins to become more clear for the clinical community, and more slowly, the general public.

[@jodydavison33]

I haven't heard garbage in garbage out since my high school teacher said it to us 50 years ago. Great saying! Consuming garbage food, garbage media, garbage relationships equal big problems.

[@dennysmith5284]

Stated far better than I. Thank you! The problem is one of perception in my opinion--the general public does not perceive their groceries as dangerous, and believe that metabolic syndrome is "just normal aging...happens to everyone". It's just all "normal." Because perception is reality, we have a long road ahead of us to get them to the actual reality. @@jodydavison33

[@chris_ea]

❤ - Why is this so hard for “others” to digest?? The world needs access to this knowledge

[@neelamkaur1965]

Every time I hear Dr Lustig I learn more and feel I am in control of my health

[@stephenn3727]

Dr Lustig is a true American Hero!

[@donwinston]

He is a quack and you are a moron.

[@dchildr360diurnalnutrition]

Wow! I will review this video over and over for it’s great detail and information - for the rest of my life. Thank you for the work you’ve done.

[@ecotechwithLS]

Always enjoy Dr. Lustig speech, wish I were there.❤

[@lindak5036]

I love Dr. Lustig and follow him and keep myself healthy. I worry about his health because of size of his stomach. How about a MRI to check the visceral fat?

[@gtm5650]

On other episode he did mention up to 10Kg of subcutaneous fat is fine before metabolic syndrome kicks in

[@jodyjackson5475]

His visceral fat is the problem. He needs to chat to Dr Sean O’Mara and get an MRI

[@ScottLSimon]

That does seem to point to something worth talking about. If you are an expert on healthy food then you probably should be healthy.

[@jameshoey303]

lol

[@marcdebruyne3258]

someone who sees that he is not doing well with a healthy diet, you do not become so obese, sugar and carbohydrates are not the bad guys, see durian rider, he only eats fruit and white rice and white bread, but no oil or fat or animal proteins and sees It's a lot better to have time to think about it, right?

[@mikecain6947]

A study with a ketogenic diet or sugar free diet in people with Alzheimer's would be easy to do and would rapidly show results and would be of great value to society.

[@patriciaalford1470]

Dr. Dale Bredesen, neurologist and Alzheimer's researcher, has developed the RECODE protocol, a multifactorial, precision medicine treatment protocol for Alzheimer's Disease, which includes a ketogenic diet. He has published the (largely successful) results in case series (10 pts, then 100 pts.) and a small clinical trial. His popular books include "The End of Alzheimer's", "The End of Alzheimer's Program", and "The First Survivors of Alzheimer's". Before Dr. Bredesen's publications, Dr. Mary Newport published her observations of improvement in her AD-afflicted husband's cognition when she administered exogenous ketones (coconut oil, which contains MCT oils, then MCT oils), then used a ketogenic diet. Deficits in brain energetics are a key pathology in AD, but are only one piece of the puzzle. Dr. Bredesen has identified multiple types and subtypes of AD and multiple underlying factors that must be addressed to not only halt the progression of cognitive decline, but to reverse it. Inflammatory (infections, metabolic, air pollution, chronic stress, defects in blood-brain barrier, etc.), lack of trophic factors (nutritional deficiencies, poor gut health, hormonal deficits, lack of exercise), toxins (mold, heavy metals), etc. Most AD patients have multiple causative factors to be addressed in addition to their diet, but almost all will benefit from a ketogenic diet and/or administration of exogenous ketones.

[@blaze1148]

" _.....even the Lancet guys have figured this out - and to be honest with you they have figured much of anything else_ " Dr Robert Lustig 2023 *So true !*

[@Emerypharma]

😂😂

[@hugoapresname]

Emery Pharma Your KZbin Videos are a great blessing! Dr. Lustig raises our awareness about what food is *made* of! Greetings from Germany 🇩🇪 😅

[@Emerypharma]

Thank you for your kind words! Our mission is to help save lives!

[@eloiselovesdevi]

Love love love Dr Lustig!!!

[@citizenjournalist2533]

Why is he so fat though?

[@EternalLife42]

He did this for me! Thank you.

[@elinmansson5535]

I love that Dr Lustig is now also talking about mental health!!!

[@mannyradzky493]

He is the best Dr on the internet.

[@notadonna5983]

Wow! Thank you! This was a critical eye-opener for me trying to heal from a chronic illness.

[@aurapopescu1875]

Dr. Christopher Palmer, "Brain Energy" Dr. Matthew Philips Dr. Georgia Ede

[@farrokhfarr2694]

Dr R L talks I lessen. Lovely gentleman

[@recipesforahealthylife]

I cured my 7 year old child's Tourette's Syndrome with a natural diet. The child took antipsychotics because the tics were very severe. Now he is healthy and does not take medications. I started by cutting out excess fat in my diet, then reducing my intake of sugar and white flour. I'm happy, nutrition is incredibly important! Health to you all!

[@girlcurious]

Thank you for making this presentation available. 👍🏻

[@Emerypharma]

You are welcome! Our goal at Emery Pharma is to bring fact based knowledge to everyone.

[@OIOnaut]

I got a second chance to life much thanks to Lustig and like-a-likes. Still time has shifted my focus less towards a diet. I have been low carb, keto and carnivore more than ten years. Now living no plants lifestyle with flawles un-illness. This is not the big picture. Not even close. Melanin explains everything Robert says. Why do not people see it is my conundrum. My focus has shifted towards POMC, leptin-melano cortin pathway in bioquantum frame work. I have a solid state optoelectric research background in semiconductor research. QuantumHealth seems to be underlying the chemistry and biology found to manifest these problems in the foods we consume. I claim that in real life we consume the light from the skies and transform it to energy by mitochondria and food exacerbates the machinery to enable all this. It is a story of light at first principles. It is the Light I see under the topis what Robert talks about. Blue light toxisity messing with circadian signaling, resulting in mitochondrial dysfunction. Some issues with pestisides and plants own phytochemical warfare in foods interest too. Not to forget the deuterium factors in this wide-band semiconduction hypothesis. Food is only a barcod of the native EMF we get from our star during any day and night plus the UV-frequency emission every cell makes with melanin when the sun is not shining. That is the bactreria and eucariot connection. Signals that are coherent. Where do you live? Do you eat food of that latitude?

[@notadonna5983]

Very helpful insight! Thank you for sharing!

[@billboyle1588]

Chloroplast Man! Thank goodness!

[@SpearChuckUngawa]

Congratulations Mark! I too sent my ALT plummeting to 18, one time 17 by going keto. I took Dr. Lustig's advice on limiting sugar, plus wheat, corn, rice and soybean oil to 9 tsp/day. My honey limits the aggregate to 6 tsp/day. The result flipped our health to where I can mow the yard at noon, without a break, in the middle of an Orlando August. Mentally I can read without wandering so comprehension is better.

[@Emerypharma]

So happy to hear!!

[@catchristo9406]

6 tsps honey each day? Wow. That's a lot.

[@Precaria]

9 tsp/day of soybean oil is still destroying your organism. Why not swapping it for avocado oil?

[@SpearChuckUngawa]

The aggregate of all 'is' 9 tsp/day.@@catchristo9406

[@tedangle8224]

I like his sense of humor, lol, I've learned so much from this man and I'm still learning from him!

[@joecaz]

34:45 ...a compound that is made from an intermediary metabolite of fructose called methylglyoxal. It is the breakdown product of dihydroxy acetone phosphate. Okay, it can fit in that active site and it is an aldehyde. And what happens when an aldehyde and an amino group find each other? Right. So, here's the Maillard reaction. If the rate of the glucose at the Maillard reaction is one, fructose is at seven, methylglyoxal methylglyoxal is at 250. So methylglyoxal methylglyoxal is a bad guy, okay? Because it is binding to proteins whether you like it or not, okay? and it fits in the active site, so it fits in that AR you know, finds one of those arginines in that active site. So, the methylglyoxal gets made from dihydroxy aone phosphate from fructose fits inside there and then you turn off your AMP kinase irreversibly! You have basically killed your AMP kinase. So, your AMP kinase goes down; what does that mean for mitochondrial biogenesis? It means it's in the sewer; it means you have decreased your mitochondrial function. and if you decrease your mitochondrial function, what does that mean for your cell? It means your cells are starving. And is that going to have any behavioral effects if it's in your brain? You bet it will!

[@MrDDiRusso]

SORBITOL CONVERTS TO FRUCTOSE! SORBITOL IS THE KEY INGREDIENT IN MANY "SUGARLESS" CHEWING GUMS! THIS EXPLAINS A LOT!

[@Emerypharma]

Yes it does!! www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/sorbitol#:~:text=The%20sorbitol%20pathway%20converts%20glucose,NAD%2B%20oxidizes%20sorbitol%20to%20fructose.

[@crcharrt917]

Neurological specialist in London always said they didn't know the reason why my mum and brother got sick with motor neurone disease, my brother being obese had it 20 years earlier than mum. I am sure that living by a ketogenic diet and moderate exercise is helping my brain and hopefully I will not be affected. It seems increasingly the case given all the studies and facts I'm hearing, that I'm now more aware of the cause than the specialists in London.

[@kinleydorji]

Great talk, as usual. Thank you!

[@psdaengr911]

It's not just sugar. All carbohydrates that can be digested have the same effect.

[@yakoobyasseen2539]

What a great teacher! And proven science researching for real food and thank you for sharing this information from Johannesburg South Africa 🇿🇦

[@LovingColorado598]

This knowledge can change the word...back to how our brains worked before the industrial food revolution

[@ricardoherrera6632]

Another amazing conference

[@davethe-bear9923]

Best presentation yet thank you Dr. Lustig. And thank you Drs Palmer & Johnson.

[@yosefsugi1808]

thanks Prof Rob & all emery pharma team 👍👍

[@erickeytie173]

The true definition of what being a doctor means !

[@funnyandfat]

Hi! Thanks for the video :) will keep an eye out for updates

[@celinemartinez7831]

I like how Dr. Lustig addressed the child's diet by making meals for parent and child. They were both supposed to eat. Kids can't buy their own food yet. Adults make the choices. As we heal ourselves, kids, grandchildren stand a chance.

[@tomm5228]

Keto 10 months minus 56 pounds and 2 meds, keep it simple

[@ldsjen0227]

I can’t do keto. I did that on and off throughout my life until I was in my early 40’s and learned I have a CBS Homocysteine issue amongst others and to much protein can kill me… 🤦‍♀️ I can’t win.

[@shvonned.burkemsncrnpagpcn619]

How lucky you are to have had him grace your presence! (Ok that’s a lot but heeeez goooood 😝) ❤

[@vtheb1299]

I have huge respect for Dr Lustig but I was surprised that he advocates keto. He says he does it because the jury is still out on whether it's the keto or the elimination of sugar that has the positive effects. But I read the Yudkin 1974 book Pure, White, and Deadly that Dr Lustig recommended elsewhere (and wrote the introduction to) and it talks A LOT about studies comparing sugar based diet to starch based one. It seems to have already answered the question whether it's the keto or the elimination of sugar, way back by 1974. It also talks a lot about the importance of using animal models that are omnivores like us, otherwise you don't know if the negative effects is simply because you're just feeding the animals stuff they don't eat in the first place. I don't know if fruit flies' natural diet is sufficiently close to the human one, but rats are, and they're mammals too, so this gives the opportunity to study for example pregnant rats and the effects on their babies, which Yudkin also talks about. Keto is also known to be contraindicative for females (at least in fertile age, because it disrupts hormones) and absolutely so in pregnancy, so I was surprised that Dr. Lustig didn't mention sex differences throughout the whole talk, especially given that 2/3 of AD patients are female. Just think about it, the diet that best promotes baby's health and development in the womb is most likely the best diet period, and conversely, if it is contraindicated, this should give anyone pause. Dr Lustig also mentions the negative effects of meat but not that it is nutritionally challenging to be on a keto diet and vegetarian (unless you eat copious amounts of full fat cheese etc, the health benefit of which is dubious) and virtually impossible to be keto vegan, because pulses like lentils, beans, chickpeas don't pass the keto threshold, restricting the only source of protein to nuts and seeds. As another doctor mentioned, every known culture on the planet historically has eaten starch. The problems observed today correlate with the advent of sugar in human diet, not starch. This is also proven in generational studies of migrants to the US and their children. So I'm not convinced that keto is the answer. No fad diet can beat good old plain real, whole food, in moderation, combined with physical activity.

[@lymphomasurvive]

You’re talking about large civilizations that needed cheap food, which is starch. People have thrived for millennia on no starch. The human body can live without carbohydrates but it cannot live, well or for long, without fat and protein. Many women are more fertile after starting keto diets and native women all over the world have breastfed without starch in the diet. You mention vegans but no human society has ever been vegan.

[@juvenalbranco2411]

Amazing. Gratidão 🙏

[@EddieBuck327]

Great job

[@AntoineGrangier]

So interesting. Thanks Dr Lustig.

[@Emerypharma]

Glad you enjoyed it!

[@redpill8274]

لقاء في القمة....شكرا جزيلا

[@ramilapatel6746]

Dr Lustig is inspirational providing knowledge to empowering us to make better food choices 🙏🙏

[@tracybenson6364]

I found sugar in my kombucha, in my canned vegetarian beans, in my stewed tomatoes. I try to completely avoid all added sugar and ask my clients to do the same. Its increasingly difficult.

[@Emerypharma]

You are absolutely correct!! You have to prepare your own meal to keep the sugar out

[@t.corazon6350]

Eat fresh untouched food: eggs, yoghurt, broccoli and the likes, fatty fish, meat, coconut oil of butter, or lard. Or olive oil. etc. Everything that has lived or grown of flown or swum!

[@SkepticalTeacher]

Kombucha does need sugar as an ingredient because it is a fermented drink, so the bacteria used to make it feed off the sugar in order to produce the drink, like the cultures in yogurt or bread, same principle. Check the ingredient list but then look at the sugar content per 100ml and it should be very low. If it's high, that's because the manufacturer has added extra sugar for sweetness.

[@Oracle4DeAtlantis]

Nice work…

[@dannereading9584]

Excellent information!

[@Creolady925]

After almost a year of hearing his lectures i finally gave up the white sugar. I do the green one sparingly and I drink diet colas. My next step is to get off the green sugar packets and to give up soda. They say sugar is harder to quit than illicit drugs and i believe it 😊

[@t.corazon6350]

It can be done…just be strong!

[@eulalia3446]

Dr Lustig - I love watching your talks... but please address your bulging gut ....we want you to remain well.

[@farrokhfarr2694]

😂❤

[@blaze1148]

He needs to practice what he preaches 😉

[@proudchristian77]

U want him to look like a stick , u need meat on your bones, just not to much , y we exercise, & don't pig out ! whallah 💝

[@jodyjackson5475]

No not just bones. Just more muscle than visceral fat ❤

[@chremis]

Remember being overweight or obese is not causative to poor metabolic health...that's old thinking..it is only a risk factor...and as you get older having a little extra subcutaneous stored energy is healthy...imagine how busy the doctor is as a leading light...no worries on this one

[@booswalia]

Ultra processed foods could be made healthy but I don't believe they could ever have the shelf life required to get them ON the shelf.

[@vegasrichsave]

Thank you Emery pharma!

[@AmyMeacham]

So much info! He’s a treasure

[@florarezai2979]

Dr. Lusting, I am a long time follower and love your lectures. What is the easiest way to eliminate fructose? Fruits have fructose too? What foods besides processed foods shall be eliminated.

[@stephengillihan7568]

I'm 2 years carnivore. Eat meat and seafood, eggs, bacon and water. I've always never considered myself a sugar eater. I drank beer. My unintentional choice of sugar. 55 years. Just this month I realized I am a sugar addicted. It is built into us. I quit drinking alcohol 6 months ago. I allowed myself some have some Häagen-Dazs ice cream after a fast. Mistake. I ate Häagen-Dazs for 3 days. Nothing else. Sick and depressed. I climbed back on the carnivore horse. Now I know. Which is powerful.

[@meenakothari7841]

We can be the change we want to see.Its imp to talk to people and give them ur time. U never know how Your simple act of lending a ear even to strangers might help them feel accepted and lessen their worries

[@bardwessel4663]

What makes this here Lustig's possibly best fitting form of presentation to aim at deniers? It's to the lesser demanding of a certain level of understanding by being directed more broadly and general, while it's still including the "to be continued" (glucose versus fructose) that even if amazingly so is sought to be hanging very loosely in the ear. Not even health specialists are much involving it at all, not even while informing of the obesity risks that's concentrated around the will or the lack of will that's no doubt wrongly and irresponsibly focused in directly harming manners, let alone the fructose's work on dopamine that'll soon get one kinds of very little amusing attention where "sweet is our culture" seems still to be representing a wall that's making for incredibly much of an impenetrable landscape.

[@Strutter-direct]

Rob's a master of conveying such complex subjects.

[@gabymalembe]

People in Hong Kong live 8 years longer than we do. They eat lots of vegetables, lots of seafood and meat, way less sugar tha we do.

[@soliver111]

Another great presentation. I am confused about the association between glucose and fructose. Is there an introductory level video that reviews this in more detail? In particular, how the the body processes both molecules. Thank you very much

[@Emerypharma]

See our other videos

[@Emerypharma]

@emerypharma

[@KNITTERSGAMERSDIAGALONCMHA]

How would an undiagnosed chronic Candida infection in the small bowell affect mental health?

[@joecaz]

25:22 Glucose actually stimulates mitochondrial function. So, you'll notice beta oxidation up arrow in green, hooray! that's good. Glucose increases mitochondrial function. How does it do it? It activates two enzymes right here. IT ACTIVATED AMP KINASE, adenosine monophosphate kinase; this is the fuel gauge on the liver cell. When your cell uses up ATP, it makes AMP, right: Because the phosphate bonds get broken and that's where the energy is; it's in those phosphate bonds, that's what the electron transfer support chain in your mitochondria do. It's they basically release the uh uh energy and you turn into NADH and then go back and forth, Etc. You know, that's that the whole oxidative phosphorylation that powers cells. everybody familiar with the concept? Right? Okay well, AMP kinase. Okay if you have more AMP, it fits into the active site and what that does is that tells the cell "not enough energy, we're energy depleted because I've got AMP instead of ATP. And so, we need to make more mitochondria." So, it increases mitochondrial biogenesis, which is good for burning more energy. In addition, it increases this enzyme here called HHDH hydroxy acetyl COA dehydrogenase, which is also involved in increasing the rate at which two carbon fragments get converted into energy. Thus beta oxidation go going up. So, glucose for lack of a better word is good . Fructose on the other hand is another story. Fructose does the opposite; fructose inhibits three enzymes that are necessary for normal mitochondrial function. [It inhibits AMP kinase, it inhibits ACADL, and it inhibits CPT 1A.]

[@peggyharris3815]

Xylitol inhibits the growth of streptococcus mucans orally. Should we replace cane sugar with xylitol? What is the effect upon the gut microbiome ingesting xylitol?

[@Emerypharma]

Research it. It may be a good alternative to fructose! And sucrose

[@dalialovesdoggies4361]

​@@EmerypharmaStevia

[@mbea1367]

I'm currently trying to recover from an episode of colitis (assumed bacterial) which resulted in a hospital stay, later diagnosed with C-diff and started on vancomycin. So I have some medical issues. In the last week I watched a youtube video on xylitol & dental health, so I started chewing xylitol gum a few days ago. It's too early to tell if my teeth will look better and if the bacteria in my mouth becomes healthier and will that help the bacteria in my gut improve?

[@peggyharris3815]

​@@mbea1367your teeth won't look better but they will feel smoother to the tongue. That means that the harmful bacteria can't stick to the tooth surface. Gut wise... most people experience some gas in the beginning. It's worth creating a habit of xylitol for oral health.

[@lucynasloanewilliams8725]

Fabulous presentation! Will need to watch again though. :)

[@charliesgrumma5388]

I've found that increasing my animal fat intake greatly reduced my "snack cravings" in-between meals making my OMAD "ketovove" diet much more doable. This may work for others who suffer from snack cravings between meals.

[@CeliaSpain130]

Why is he obese???

[@charliesgrumma5388]

@@CeliaSpain130 If I had to guess I'd say it is because he ate a "heart healthy standard American Diet" until he became fat, diabetic, and metabolically damaged before he learned what the "Proper Human Diet" was. And now that he knows he is trying to repair his body and warn others of the dangers of improper diets. Visceral fat takes a long time to go away and his will eventually. I'm 5'10" and weight 209 pounds. In Feb 2023 when I started a "ketovore" diet I weighed 321 pounds. Even though I've lost over 110 pounds I still have a pot belly too. But it is a hell of a lot smaller than it was. I no longer need meds for my type2 diabetes or the 2 high blood pressure meds I had to take eating a "healthy low carb nutritious American Diet" consisting of 300 carbs per day that caused me to balloon up to 321 pounds before I figured out what to eat and the "SAD" isn't it..

[@charliesgrumma5388]

@@CeliaSpain130 A better question would be, Why are you stupid? He can always lose weight.

[@Jimmy-Legs]

Looks like the good doctor has been hitting the donuts.pretty decent gut there.

[@charliesgrumma5388]

You remind me of a house fly. Eat shi, uh, crap and bother people.

[@dirkk.6573]

Would that mean that Keto-Diet might fix Long Covid? I mean if, as partially assumed, Long Covid is some sort of major disfunction of mitochondria?

[@csmrfx]

@07:30 Ketones are transported by MCT cell surface protein, which are always expressed in cells and function without insulin activation. See Wikipedia article Monocarboxylate transporter.

[@sandramancilla4130]

Love him 100% great Doctor!!!❤

[@mypartybag]

Where can you purchase Munch Munch, I have searched the internet and it is nowhere to be found.

[@MengzisDisciple]

The only issue I would have with his explanation is he seems to skim over the fact that manic-depression and schizophrenia stem from the insula and its connection with serotonin and DMT. He is correct that the amygdala needs to be "neutralized" to reach the background insula system by moderation (vices). But the insula also has to be moderated (virtues)-too much mania just leads to depression when you use up your stash (pride being what leads to your fall like Icarus or Lucifer)- or ask someone with bi-polar disease how this works--which the insula is the system associated with it. Where the only way to get out of the depression is to have "purpose"--such as telling others all about your experience with the insula, and why so many "woke" people feel the need to tell everyone how "empathetic" they are, which is also connected to the insula (the foundation of all religions and most philosophical systems). "Almost all recent imaging studies of emotion report joint activation of the AIC and the ACC in subjects experiencing emotional feelings, including maternal and romantic love, anger, fear, sadness, happiness, sexual arousal, disgust, aversion, unfairness, inequity, indignation, uncertainty, disbelief, social exclusion, trust, empathy, sculptural beauty, a 'state of union with God', and a hallucinogenic state (induced by ayahuasca). Thus, the AIC is activated not just in association with subjective feelings from the body, but apparently with all subjective feelings." Dr Craig "How do you feel - now? The anterior insula and human awareness | Nature Reviews Neuroscience" You also have to be careful not to harm the amygdala (not enough dopamine) as traumatic events (death of a parent) leads to schizophrenia; as does too much meditation and not enough sugars in your diet--as DMT is also connected with the insula system (the subconscious part of the brain connected with sleep patterns and dreams). This last why so many use LSD/DMT/Magic Mushrooms to over-ride the amygdala and tap into the dream system of the insula. Not the smartest move conducting science experiments with chemicals in your brain.

[@NG-iy5rq]

Dr. Lustig is a giant.

[@Rocky7729]

Why is it that some doctors only talk about sugars and it’s effects on health only when they retire ?

[@jeaniecurry4512]

Yes it's very typical when you get rid of the carbs that you are good LDL the big fluffy ones will increase which will then give an overall increase in the total LDL number that's why you have to have your doctor break that particle number down so you know which one you're dealing with

[@carlaann12]

Great lecture

[@nidhibahl5875]

I know more than the doctors thanks to talks like these

[@Robinhood179]

So based on what he said at around the 1:14:30 mark, how high is a medium carb diet and is he talking about letting bad carbs slip back in and not fruits and veggies in a whole food diet? It doesnt take much to go up in carbs but if they are clean, mixed with a high fat diet, is that still a recipe for disaster???

[@Cloudkaos.]

Goddamn Hero this guy, few people with this character , modern hero i say

[@Emerypharma]

He is fearless!!

[@carolbrenner3121]

How do you get the slides ?

[@Emerypharma]

Slides are not available. Sorry!

[@mildredrodriguez5086]

Podrian poner subtitulos en español..❤

[@blaze1148]

One question for Robert - if Fructose is so deleterious to Human metabolic health why have we evolved such an enhanced _reward_ response to it ?

[@CarnivoreDMD]

In the natural environment, except for very limited equatorial environments, fructose (fruits-berries) are very limited & seasonal. The “fruits” which we buy today ARE NOT the original smaller & more fibrous fruits found in nature. The fiber binds the fructose & gets it lower into the GI system where it is absorbed slower. Our desire to gorge fructose is a survival instinct just like in animals preparing to hibernate. Unfortunately, we now get fructose exposure 365 days/yr which results in chronic metabolic dz.

[@blaze1148]

@@CarnivoreDMD True. But it still seems counterproductive - there is nothing in fruit that you can't get anywhere else.

[@CarnivoreDMD]

@@blaze1148 think….50,000 years ago diet. You’re eating what is in the woods. If you find late Summer Muscadines, you gorge. You get fatty liver, a good thing temporarily, now you are hunting animals, might not eat for 2-3days. A perfect system also for hibernating animals.

[@lymphomasurvive]

@@blaze1148Ask the same question about alcohol, heroin and crack cocaine.

[@thanosfotas4396]

at 46:00 Lustig says that insulin inhibits leptin signaling, ive been trying to find papers that confirms that information but without sucess, can anyone help me out?

[@annalexander6042]

Dr why don't you allow lentil soup on your diet or soups

[@avlasting3507]

Is the upshot that we shouldn't eat fruit?

[@brookstorm9789]

Does the liver make enough beneficial glucose or do we need to get more from our food? If so what gives glucose without fructose?

[@mj8495]

The liver supplies sugar or glucose by turning glycogen into glucose in a process called glycogenolysis. The liver also can manufacture necessary sugar or glucose by harvesting amino acids, waste products and fat byproducts. This process is called gluconeogenesis.

[@brookstorm9789]

Thanks MJ. I thought I heard Dr. Lustig mentioning how good the glucose is. I was wondering if we needed more than gluconeogenisis provides from a carnivore diet for example. In other word, should I have razzleberry pie after my hamburger meal? Dr. Paul Salidino says he added carbs, fruit, to his pure carnivore diet and feels much healthier. Happy da!@@mj8495

[@razorgenshin7265]

​@@brookstorm9789High fiber starch is high in glucose without causing insulin spikes. These are mainly legumes like beans, peas or peanuts. Also, pie in general has too much fructose so not a good idea.

[@paradigm5084]

I’m mind blown

[@annalexander6042]

I had my trucility 75mls today at 3pm dr

[@SarahAndreaRoycesChannel]

If glutamat is a player in the biochemistry is glutamat as part of many hpc products dangerous in itself?

[@Emerypharma]

Just posted a new podcast with Rob Lustig focused on: Vitamin D, overdose or under-dose, Ketogenic Diets & Personal Responsibility kzbin.info/www/bejne/j3W2mYWXgruNeKM

[@williamlagakos9609]

No ketone receptors or transporters? SLC16A6? HCA2?

[@miguelgarciapoujol3127]

Great 🎉😊 aprendí mucho