Clomid Vs Femara | Which is BEST for PCOS to get Pregnant? [CC]

Clomid and Fermara are commonly prescribed to women with PCOS and other diagnoses, as a first treatment to try and get them pregnant after an infertility diagnosis. This video covers the pros and cons to both as a fertility treatment for those with PCOS. I also cover the risks of each medication and the twin rate with each. Learning how to self-advocate is one of the hardest parts of infertility! In this "Skill Up" series I am hoping to equip you with the knowledge you need to have an educated discussion with your doctor. Obviously I am just a fellow infertility warrior, so please consult your doctor on all medical decisions.
#ClomidSuccess #FemaraSuccess
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After 2.5 years of battling infertility we welcomed our little baby girl Evangeline into our family on July 18th, 2019. You can check out the other videos on my channel to see our journey to starting our family. Be sure to subscribe to see how we grow our family next. I love hearing from you all so leave your comments below!
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I am not a doctor just an infertility warrior that researches a lot. Please consult a doctor on all medical issues, treatment, medications, and advise.

[@JAKSJourney]

Comment below if you have any other questions! On this channel I am hoping to grow a community that can help each other on their infertility journey - keep on fighting ladies!

[@unknownpassion8914]

I am taking my 2nd clomid tablets today night... I have pcos... But my periods are regular

[@unknownpassion8914]

Does it works

[@thekings8993]

IRL JAKS witch do I use if I for sure want to have twins

[@unknownpassion8914]

@@thekings8993 do you have regular cycle

[@T3COLY]

Unknown Passion I am the same. Did you get pregnant? If so, what was the dosage ?

[@RosannaChistiakov]

Thank you! Was looking for that information and comparison for weeks! Very informative! 🔥

[@JAKSJourney]

Happy I could help!

[@nicholegaffney83]

I've been to several doctors but never have I gotten this explanation or clarity. Thank you :)

[@JAKSJourney]

So happy to help! I fear many women go in to the doctor's office and only come out with a diagnosis and a RX, but no information.

[@nalanibby93]

I’ve been diagnosed with PCOS and been trying for 7 years with no success, I’ve thought about giving up on having my own baby but I’m staying strong and getting help. Thank you for your video 😊 very informative.

[@JAKSJourney]

You are so very welcome! I am wishing you the best of luck on your journey and I hope after all these years you get your precious little one.💙

[@heidin1544]

Thank you, this is SO helpful!

[@JAKSJourney]

You are very welcome! Glad it was helpful.

[@atdepaulis]

This was awesome thank you!

[@phoenix8112]

Femara is better. My wife had two miscarriages (12 week and 3 weeks) and later, going through many unsuccessful rounds of clomid, she underwent cleaning of uterus (HSG, I think) and next month she got pregnant. Maybe after your miscarriage your uterus is not clean and therefore pregnancy is not possible. Thanks to Allah, we have a baby now.

[@JAKSJourney]

I am so happy you and your wife got your rainbow baby!

[@navifoursnavifours6490]

Femara ketne month Liya bro pls replied

[@navifoursnavifours6490]

From Bangladesh

[@mugishaprimeroger728]

Hongera sana

[@AJGorby-mw6ci]

Great easy to understand video. Love the artistry to visually show the differences. I'm a man and my wife and I have been struggling with fertility issues for almost 4 years now. I recently got diagnosed with hypopituitary hypogonadism. I will begin Hcg & Clomid this week. I have a lot of knowledge on hormones both endogenous and exogenous so informative videos like this are highly appreciated. One thing I always wondered (which you explain in your video) is the mechanism of action Clomid has vs Letrozole. Clomid works on the brain and Letro works on the ovaries. My understanding is HCG works on the ovaries in women and testes in men similar to Letro. My question is I wonder if HCG is interchangeable with Letro since they both work on the hormone production front (opposed to the pituitary/brain front). I do not like the risks and side effects Clomid has so I have always tried to avoid Clomid. In the past I've taken Tamoxifen + Clomid together for TRT recovery purposes. Anyway, thanks for the video!

[@nicoleowens05]

I was listening I promise! But your writing sooth me lol! I’m a fantastic on the asmir videos, so I could’ve watched you write for hrs🤣😂🤣

[@JAKSJourney]

Hahaha that is great! Maybe I'll break into that niche next :D

[@jasmingalvan915]

Omg !!!!!! Thank you thank you seriously very appreciated

[@JAKSJourney]

Glad I could help!

[@leenaparsons9876]

Thank you so much! This was a great video and the visuals really helped. You should be a teacher! lol It's so much more empowering when you are armed with knowledge.

[@JAKSJourney]

Aww thank you for such a kind comment. (Secretly I would love to be a teacher!) Best of luck!

[@sandydasilveira2591]

Great info thank you!

[@ArielcHarrison]

This is so helpful! Thank you so much!

[@JAKSJourney]

You are very welcome! Thanks for watching!

[@ArielcHarrison]

@@JAKSJourney Yes, I am currently on my first round of Letrozole, so it was great to learn the differences between these two drugs.

[@JAKSJourney]

Good luck! Sending BD your way ✨

[@loritamills1341]

Do anyone stop your period .I'm on my 2nd round of clomid 50mg and it stopped my period I took it days 3-7 my cycle are 28 day now I'm on cycle day 33 still no period and native pregnancy test.

[@JAKSJourney]

@@loritamills1341 Hmmm I haven't been on Clomid but when I am on Femara I have a mixed result of my period coming back or not.

[@mehdiyamohammed3097]

U are smart thank u for learning more

[@JAKSJourney]

Thank you!

[@TheFakeyCakeMaker]

TWINS! YAAAY!

[@malonjephiri3477]

Very helpful video thanks

[@JAKSJourney]

Glad it was helpful!

[@Chimaki1]

Thank you so helpful. My doctor just gave a me low dose of femara. I will start next month.

[@JAKSJourney]

You are very welcome! Good luck on your next cycle; I am sending BD your way ✨

[@emanfareed5047]

Does it work

[@NinaDemons]

Update ?

[@Abdulraffay_world]

Hi what I do I have taken clomid n I m not pregnant nor having periods

[@SucdiMohamed-og7bi]

Hello mam I hope u see my message.I am 19 years old I have a regular period of 28-34days I was diagnosed with pcos on both ovaries my Gynecologist sent me blood test and all were okay 👍.until my Infection were 50 instead of 0-20 range she gave me some medication ❤And Prescribed clomid for me from day 2-5 100mg I hope it works For me the first round and Am 49kgs currently I actually don’t have Pcos symptoms like gaining weight it’s so hard for me gain weight.she diagnosed me with mild Pcos and said it’s not sever ❤️I hope clomid works and I conceive first month ❤️

[@sarielizard1]

Thank you!!!!

[@JAKSJourney]

You are very welcome!

[@kayinjoy3690]

Thank you!

[@JAKSJourney]

You are very welcome! Thanks for watching!

[@lesleygrossmann1336]

I have Pcos and Femara did not work at any dose for me then my doctor wanted me to loose weight and try femara again she refused to use clomid on me because she doesn't want multiple babies she said she doesn't prescribe it to hardly any of her patients. After that we just decided to give up.

[@JAKSJourney]

I am sorry to hear of your struggles. Femara alone also didn't work for me. We had to add stims to my protocol for it to work. Don't give up hope!

[@nanasaleh6964]

I’ve been taking clomid for 6 cycles, I ovulated successfully with it but no pregnancy. Tested for pcos but not detected. My doctor is going to have me try cycles of letrozole now. With the fact that I ovulated with no pregnancies on clomid, will letrozole possibly have a different result with getting pregnant even though clomid worked for ovulation?

[@JAKSJourney]

Confirm with you doctor, but I am guessing that they switched you because there is usually a 6 cycle limit on using clomid because of long term side effects and increased risks of serious side effects. If you didn't ovulate every time on clomid they may be experimenting to see if you respond better to letrozole as well. Best of luck!

[@Mmarkitastamps6078]

I’m on femara now I’m so excited having PCOS is a hard journey

[@beachnap]

In PCOS women who struggle with high androgen symptoms, does Letrozole exacerbate that by raising androgens/testosterone? Also, how does it affect LH levels (which are commonly 3x higher in PCOS but flat-lined throughout the cycle)?

[@JAKSJourney]

For you first question I don't know the answer and would encourage talking with your doctor about. With medicated cycles you should still experience a LH surge. My doctor discouraged me from using at home tests since PCOS makes them virtually useless. Instead she confirmed ovulation with ultrasounds since it is more reliable.

[@melissahernandez8143]

If am taking both medication on Clomid 2 tablet and 1 tablet Femara what is my change of getting twins ?

[@JAKSJourney]

That would be a great question for your doctor! My thought would be that you would fall into the Clomid range for twins though.

[@ImranKhan-cy3vd]

Love this video from Saudi Arabia 😊😊😊😊

[@JAKSJourney]

You are so welcome! Thanks for watching all the way from Saudi Arabia!

[@bikosteve6973]

help l used Clomid 3 times but is donst wark far me my question is can l try Clomiphene or letrozole

[@JAKSJourney]

You can ask your doctor about trying Letrozole for sure since it works differently than Clomid. Good luck!

[@samiratuseidu4594]

I took only one shot of depo provera (September to December) . My period returned in February and March but very light. Can clomid help my cycle and consequently ovulate

[@JAKSJourney]

Depo can take up to two years to wear off completely. The majority of women need more than 3 months for their cycle to return to normal. I would use ovulation predictor kits(OPKs) to see if you are ovulating and chat with your doctor about how long you should wait to pursue fertility treatment. I think you should wait a bit longer before being too concerned. Best of luck!

[@lareina4212]

Which one is best

[@gisellemorel1214]

Thank you so much♥️♥️♥️

[@JAKSJourney]

You’re welcome 😊

[@NakkaManasa]

Hey mam.can you pls clarify me 2doubts actual I have PCOS so doctor did hsg tube test and after hsg doctor gave metformin to use 3minths in the first month of metaformin u conceived but in 3month ending baby heart beat topped so doctor gave pills for abortion..so we are worried if I conceive next tym again this growth problem will come? And next .....so after that we gave 3months gap..so this month I got period on October 1st and took clomid for 5 days and follicular monitoring also so doctor gave hch injection on day 12 and my egg rupturd on day 14 so we are in contact from day 12,13 14 so when should I do pregnancy test on which day tell me

[@bithiahbrown5093]

I am also trying to learn about self-advocating for infertility. I was on my first round of Clomid in September 2018. We were just trying the Timed Intercourse route hoping it would be cheaper and get the same results. The downside of Clomid was I did end up with so many ovarian cysts. I was in so much pain. I asked for another medication expecting femera, but they placed me on Follistim instead for this month of October 2018. However, thank you for the very detailed information on the difference. I can rarely understand this stuff.

[@JAKSJourney]

You are very welcome! Sending BD your way ✨

[@jaysdelight9174]

Hi, how did you time your intercourse to get twin boys

[@mariaoliveros1269]

Hello I finished my treatment of femara (Letrozole) according to the doctor timing chart i am now ovulating i also test with the clearblue digital ovulation kit i got a {peak 😊} my question is ive been having lower pelvic pain area both side but most on my right side ! Is this what the medication supposed to be doing ? Is this normal sign that its working ?

[@JAKSJourney]

Some women do feel themselves ovulate and can even tell what side they ovulated from, so that might be the pain you are feeling. If it last more than a few days, I would bring it up with your doc. I have my fingers crossed for you.

[@mariaoliveros1269]

Thank you very much 🤞🏼❤️

[@fatmaalihassan8147]

hi ladies can u pleas tell me when will i start the fémara medicine cyz i forgot what my doctor said to me

[@alibentz8692]

fatma ali hassan call your doctor! Super important!

[@Chitram_vichitram94]

Have u got pregnant with that time of one side ovulation...

[@jojobeeslife]

Thank you for this video! I took my first round of femara this month 5 mg, I am waiting for my follicle to get a bit more mature ( ultrasound tomorrow) and then will take an ovidrel shot. I am so hopeful it hurts!

[@JAKSJourney]

You are very welcome! Good luck on your ultrasound ! 💙

[@jojobeeslife]

IRL JAKS thank you! Took my Ovidrel shot and starting my progesterone ☺️🙌🏼 fingers crossed!

[@sheltaedmond9472]

Thanks

[@ikawlangwalangiba6641]

Wow your so nice to draw hehe

[@MamtaSharma-rd6hy]

I used 3 times letrozole , now my fourth time . 12.5 mg dose per day but it doesn’t work 😒.

[@luciacorrea3878]

Letrozole 12.5 5 tables!!

[@ujjaldowari1613]

Madam AMH vulue-8.59, 42 kg weight, 30 year old, 4 year no conceive, please help to me.

[@evavandenborne1297]

"FSH, also known as LH". Thats completely wrong, they are different hormones with different functions.

[@iqrasdiary9067]

I'm on clomid round 2...at round 1 on 13 cycle day follicles scan shows 2 mature follicles...at day 18 scan shows no eggs in ovary means both eggs released..but I was not pregnant in round 1.....what should be the cause ?

[@JAKSJourney]

Even with mature follicles there is only a 20% chance of getting pregnant each month. Sending you luck!

[@shijo5849]

I have pcod irrugular period how to use the tablet

[@bonetajohnson6897]

I have been bleeding for over 2 months, doctor put me on progesterone 2 weeks ago and I took them for 10 days but the bleeding did not stop so the nurse informed me that they felt that I should stop taking the pills and he wanted my cycle day 1 to start this past Friday and Tuesday I am supposed to take Clomid, I am now bleeding lighter! But I still think I should take the Clomid what are your thoughts?

[@bonetajohnson6897]

I have also been on metformin for 3 months

[@JAKSJourney]

Hmmm what kind of monitoring are they going to do with this Clomid cycle? Ultrasounds or just blood work? Also prior to starting Metformin did you have a high blood sugar? My OB put me on that event though I didn't have overly high blood sugar because that use to be standard practice. My RE promptly took me off it because more modern studies say it isn't as helpful if you don't have high blood sugar to start with.

[@bonetajohnson6897]

JAKS Journey ultrasounds and blood work he wants me to do opk’s until I get a positive so they can do the test to see if I ovulated. I forgot to mention I have pcos and he tested me for high insulin and my results were border line.

[@JAKSJourney]

You might want to mention to him that you have PCOS after this cycle especially if you don't get a clear positive OPK. What he has you doing sounds similar to what my OB did, but after one cycle with her I moved on to an RE. OBs just don't have the training in fertility treatment.

[@bonetajohnson6897]

JAKS Journey thank you for responding!

[@wrkharshiingkharbani8361]

Mam, please tell me how many pills can I take a letrozole in a mone

[@smiatje]

What is live birth? And what is the opposite? Sounds scary.

[@JAKSJourney]

Live birth is the term used to indicate that a pregnancy ends with a healthy, happy, take-home baby. On the other hand about 25-50% of pregnancies end in miscarriages. So the pregnancy rate of a drug or treatment will always be higher than its actual live birth rate.

[@OVO-rv2do]

Hello 👋 I was told to take Letrozole from the 1st day of my period to cycle day 5 . Instead of the usual day 3-7. Please does this have any side effect? My period is starting tomorrow

[@JAKSJourney]

I am not aware of this having any other side effects but that may be something you want to discuss with your doctor. I have heard women who have been prescribed it earlier like this. I think it comes down to doctor's preference/experience, but I will add it to my list of things to research.

[@OVO-rv2do]

JAKS Journey thank you so much for replying this early, I spoke to him and he said it doesn’t matter but was quite skeptical about it. Now I can start taking it tomorrow and I pray it works. The last time I took Letrozole I got pregnant but had a miscarriage at exactly 5 weeks, hoping this time around I will take progesterone after I ovulate and get my bfp 🙏

[@JAKSJourney]

Sending you all the positive vibes and baby dust!

[@birdinnocent6714]

Which medicine is best for endometriotic patient femara or clomid ?

[@JAKSJourney]

The difference isn't as impactful for endometriosis patients but I have heard that Clomid can compound with preexisting symptoms to make them much worse.

[@sunshine_xoxo351]

Just finished my first round of femera ! Ultra sound on Monday !! Opk at home showed no ovulation right now. But may be it’s too early. Today is cycle day 12. Fingers crossed 🤞

[@JAKSJourney]

Oh good luck! It is a little early to test but hopefully you get a positive in the next few days. Fingers crossed!

[@emanfareed5047]

What happen..does it work

[@vanessaerazo801]

Alguien me puede ayudar cual es mejor para cuando tiene quistes en los ovarios

[@vanessaerazo801]

PCOS

[@JAKSJourney]

Consulte a su médico para obtener más información, pero sostengo que Fermara es más seguro para las mujeres con PCOS.

[@priyaraj5272]

hy. is Letara same as letrozole? Letara by Douglas

[@JAKSJourney]

Yes from the MedSafe site, "LETARA contains the active ingredient, 2.5 mg of letrozole and is presented in tablets."

[@singersheetalpendke513]

Right

[@Kipp929]

So my doctor told me to take my Letrozole on day 5 through day 9. Does that mean on day 1 of mences or actually day 5? Day 5 is my last day

[@JAKSJourney]

Day one is the first day of your period. So day five will be near the end of your period.

[@Kipp929]

@@JAKSJourney thank you so much for replying! God bless you . New subbie here!!

[@JAKSJourney]

You are very welcome. Thanks for joining the journey!

[@josarma394]

I am taking clomid from last 1year..I had done two times iui but not successed.gonal f 75 also

[@JAKSJourney]

Usually they cap the number of times you can to Clomid to six because there are concerns with taking it too long. I would talk to your doc about moving on to something else. Best of luck!

[@shoaibafzal7752]

With medicine you do follow proper diet and exercise

[@abdullahizainab514]

Hello I took clomid like 2 times bt it thus work on me can use both clomid n letrozole

[@NinaDemons]

It worked ?

[@sanasaniasania559]

Mam my doctor give me first month two tablets of clomind but not get pregnancycan I take clomind second month two tablets clomind again or not? Please guide me 🙏

[@JAKSJourney]

Always consult with your doctor for medication dosage. The doctor should also be monitoring you via ultrasound to see if you are ovulating. The closed may or may not be working and ultrasound is the best way to tell. If it is working, it may take several months to get pregnant. Best of luck!

[@gillgill3261]

after how many days after stopping femra...ovulation will take place

[@JAKSJourney]

It is different for every woman and depends a little on the protocol, but you should ovulate somewhere around day 13 to 15. I have heard of women ovulating at soon as CD 10. My doc did an LH blood test around CD 17 to see if I had ovulated.

[@michellecooper8687]

Will Femara make menopausal women ovulate

[@uzmakhan3091]

Which one tablet is more effective

[@swathids7046]

Letrozole

[@sheltaedmond9472]

I take clomid pills but I didn't get pregnant but I did took pregnancy test

[@JAKSJourney]

Best of luck with your next cycle.

[@NinaDemons]

Positive?

[@alibentz8692]

Just got my RX for letrozole today. I’ve worked in a family practice for a while, I’ve only seen it used for cancer, so I needed to look at more information.

[@JAKSJourney]

Good luck on your cycle! I hope Letrozole works out for you.

[@alibentz8692]

Thank you. It’s so weird to be so young and the only one of your friends who is going through this process. All of my other friends are basically always complaining about how easy it is to get pregnant.

[@JAKSJourney]

@@alibentz8692 I totally understand. It felt so weird for me to be sitting in a fertility clinic at 26 when I had been cautioned all my life to not get pregnant.

[@alibentz8692]

IRL JAKS exactly! I was adopted and my entire life my adoptive mom always told me things like “you don’t want to get pregnant and ruin your life like your birth mom right?” So I stayed on the pill faithfully taking it every day, and now we are having a hard time!

[@alibentz8692]

It doesn’t look like it worked, we didn’t do ultrasounds but I did take ovulation tests everyday from days 9-17 the line got darker, but never dark enough to be positive.

[@esperancesudi2842]

To be continued

[@PuvanesRajan]

Hi hello I already hv 4 kids but I love twins. I'm new for twins baby channel can you please help me Wat tablet should I take to get twins.. And how to take it.... Pls reply.. Tq

[@madrinekariuki3339]

Must i take the clinic exactly on the third day

[@madrinekariuki3339]

Im mean the clomid

[@JAKSJourney]

@@madrinekariuki3339 Some clinics have different protocols but all the studies I reference follow the standard day 3 to 7 protocol. Chat with your doctor about what protocol they want you to follow.

[@andreazanellato1982]

Hello, how long should you usually take(femara) , just those 4 or 5 days or then you take it for other times? I read that it causes pain, weight gain and hair loss, and this is true? What about me? Hello and thank you

[@JAKSJourney]

Make sure you are monitored by a doctor while taking Femara. Usually they just prescribe it for 5 days but which days changes based on the doctor. All drugs have side effects; reference to the manufacturer's website for a full list. Usually side effects are mild because you are only taking it for such a short time.

[@andreazanellato1982]

@@JAKSJourney Okay, thank you very much, I'm going to tell my wife, so she'il be quieter! She was scared of what we read on the internet! Thank you so much for your help! Greetings from the north-east of Italy

[@JAKSJourney]

You are very welcome and I wish you both the best of luck.

[@andreazanellato1982]

@@JAKSJourney Thank you very much again, and good luck to you too

[@obaaregi1709]

Please is it advisable to take Clomid and Letrozole together?

[@JAKSJourney]

I have never done a protocol that has used them together. You will have to consult a doctor on the benefits and drawbacks of using them together.

[@geopakistan6736]

THANKS remembering in your prayers kove From Pakistan 🇵🇰

[@JAKSJourney]

Thank you so much. (I love hearing from viewers outside the US).

[@takhellambambishota1567]

I use lectrozole 3times but i cant ovulate...

[@JAKSJourney]

I also did not ovulate with just oral meds. I moved on to a reproductive endocrinologist to add injectable meds.

[@razakiddrisu4546]

Hallo

[@JAKSJourney]

Hello and thanks for stopping by.

[@atishnade6846]

I have pcos ,my doctor give me clomid,bt it not work,after doctor give me ,famara,can it work?

[@JAKSJourney]

Yes, Femara and Clomid work differently so you can try both and get different results. Good luck!

[@baqarali481]

Hi u no urdo speek

[@JAKSJourney]

Correct, some title and description have been auto translated into Hindi/Urdo, but subtitles are only available in English.

[@marthacarrillo8255]

Thank you!

[@JAKSJourney]

You're welcome!