More EAS - Electron Donating and Withdrawing Groups: Crash Course Organic Chemistry #38

In the previous episode we discussed what happens when we use electrophilic aromatic substitution to add a group to a benzene ring, but what happens when you try to add even more groups? Well, things get a little more complicated. In this episode of Crash Course Organic Chemistry, we’ll continue our exploration of EAS reactions by looking at electron donating groups and electron withdrawing groups on benzene, and how they affect what happens when we try to add new groups to the ring.
Episode Sources:
Hammond, G.S. and Douglas, K.J., 1959. Aromatic nitration. III. The ortho to para ratio in nitration of benzonitrile. Journal of the American Chemical Society, 81(5), pp.1184-1187.
Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
***
Watch our videos and review your learning with the Crash Course App!
Download here for Apple Devices: apple.co/3d4eyZo
Download here for Android Devices: bit.ly/2SrDulJ
Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Shannon McCone, Amelia Ryczek, Ken Davidian, Brian Zachariah, Stephen Akuffo, Toni Miles, Oscar Pinto-Reyes, Erin Nicole, Steve Segreto, Michael M. Varughese, Kyle & Katherine Callahan, Laurel A Stevens, Vincent, Michael Wang, Stacey Gillespie, Jaime Willis, Krystle Young, Michael Dowling, Alexis B, Rene Duedam, Burt Humburg, Aziz, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Junrong Eric Zhu, Alan Bridgeman, Rachel Creager, Jennifer Smith, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, Brandon Westmoreland, team dorsey, Trevin Beattie, Divonne Holmes à Court, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Khaled El Shalakany, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, William McGraw, Andrei Krishkevich, ThatAmericanClare, Rizwan Kassim, Sam Ferguson, Alex Hackman, Jirat, Katie Dean, neil matatall, TheDaemonCatJr, Wai Jack Sin, Ian Dundore, Matthew, Justin, Jessica Wode, Mark, Caleb Weeks
__
Want to find Crash Course elsewhere on the internet?
Facebook - / youtubecrashcourse
Twitter - / thecrashcourse
Tumblr - / thecrashcourse
Support Crash Course on Patreon: / crashcourse
CC Kids: / crashcoursekids

[@crashcourse]

Hey everyone! There’s a typo in the structure at 10:00. The carbon on the right is missing one hydrogen atom-it should be a methyl group! Thanks for watching and understanding!

[@con_el_maestro3544]

I'm addicted to these Organic Chem videos by Deboki it's not even funny anymore... LOVE YOU DEBOKI💖

[@senpai2799]

thank you mam seriously you make these dry topics look interesting through animations and make the life of students easy

[@lemuelacosta7421]

ooh, found an error at 10:00, the methyl group at the right was written as CH2, have nothing against it tho, the video was so interesting. I really love this playlist so much!

[@leothesilent5410]

Hopefully there'll be a Crash Course Biochemistry, too.

[@paingsoekhant8731]

I really like you initiate the video with related story 😅❤

[@albenito89]

4:03 cool cool cool.. Abed?!

[@MicahFleischman]

That was meta, even for Abed's standards

[@demetrimaude6318]

so helpful

[@Saslow]

First comment! Yay! 😂

[@ByDesign333]

first....not rocket science...worse!

[@sweetcreemaker]

Third comment.. yay