A trick for figuring out if a group is electron-donating or electron-withdrawing (except for halogens), and the chemical basis behind the trick. Discussion of how EDGs and EWGs affect electrophilic aromatic substitution.
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@vedaantverma26496 жыл бұрын
Your trick doesn't work for N=O
@MolecularMemory6 жыл бұрын
You're correct, it wouldn't! But, I don't think a nitrosobenzene can actually participate in EAS. Nitrosobenzene is very reactive at the N=O group-it can undergo nucleophilic addition similar to a carbonyl AND the nitrogen lone pair can act as a nucleophile. However, there are (to my best knowledge, thanks for encouraging me to have a fun little literature search today) no reported EAS reactions of nitrosobenzenes. I'm thinking that the Lewis acidic conditions for EAS are not compatible with this group. The N=O group readily dimerizes, and I think a Lewis acid might promote that reaction well before EAS could occur (pubs.acs.org/doi/abs/10.1021/ja00827a021). I did find that someone asked this question in a problem that wound up on the internet (someone answered it on Chegg) but I'm not sure we need to worry too much about this group for EAS. Thanks so much for posting! I really enjoyed thinking about this one :)
@vedaantverma26496 жыл бұрын
Molecular Memory sorry but it does participate in EAS! I have examples....thanks for replying!
@MolecularMemory6 жыл бұрын
Oh man-I must have missed it! I was only using Google Scholar because it was Sunday and I don't have SciFinder access off campus. Please post a reference for me! I have to see these conditions. :) Thank you!
@MolecularMemory6 жыл бұрын
Crazy this did not come up in any of my searches yesterday (I was using keyword nitrosobenzene, and this didn't get anything until I dropped the "benzene")! I just found a synthesis of a para-subs nitrosobenzene in "Science of Synthesis." Doesn't seem like an efficient reaction-have you done this in the lab? Thanks for teaching me something!! :)
@vedaantverma26496 жыл бұрын
Molecular Memory no I haven't done it in lab but I referred many books for this...!!! Your video really helped thanks alot and I can't teach I'm only 16 😛....just kidding!!
@chrisjohnson11965 жыл бұрын
Thank you so much, this makes recognizing different reaction patterns so much easier
@badercriss6 жыл бұрын
You literally saved my Pharmacy undergraduate studies. Thank you so much. Now medicinal chemistry is x10 easier.
@MolecularMemory6 жыл бұрын
Great to hear! Thank you for watching.
@yepyep25583 жыл бұрын
exactly the same here
@kushpatel38612 жыл бұрын
DUDE SAME!! What a coincidence that this helped me for my MED CHEM class in my PharmD hahah :)
@bhavyachoudhary23212 жыл бұрын
@@kushpatel3861 hi are you doing your PharmD from Indi
@kushpatel38612 жыл бұрын
@@bhavyachoudhary2321 Nope, in Canada at the University of Alberta
@fatts968 ай бұрын
the way you made this entire topic easy, im so grateful thank you
@sydneypenrose95733 жыл бұрын
This is such a great way to explain EDGs/EWGs. Thank you!!
@rickyl74423 ай бұрын
This may be one of the best videos I’ve ever watched. I can explain how much difficultly I’ve had trying to work with this
@cjcjesse6 жыл бұрын
how can i express my love for you. this was 10x more useful than anything my university lecturer was capable of explaining
@bristol1946 Жыл бұрын
This is a thing of beauty *chefs kiss* Thank you for your time making these videos!
@myprettygirl916 жыл бұрын
i like how slowly you go. Super helpful!
@Giridhar_R5 жыл бұрын
THANK YOU for making this video. This trick really helped me. I REQUEST you to make more videos with tricks if you are wished to , but i really got benefited by this video.
@praveenkhare51124 жыл бұрын
No one had taught me so well until now Thank you so much
@MrKaravaj3 жыл бұрын
This is the best explanation I´ve ever heard! Thank you
@AbhinavSingh-qk4so5 жыл бұрын
There's no words in my heart to expression your help to me with mine confusion clarification. Just I can write THANKS
@asutoshmishra83806 жыл бұрын
extremely helpful, cleared up this basic concept thank you
@rd79634 жыл бұрын
It was amazing ....I was very confused and now it's all clear... thanks mam ♥️
@bjensen68104 жыл бұрын
This was very clear and helpful, thank you
@narsasak2 жыл бұрын
This makes my Organic Chem II midterm study SO much easier thank you QQ
@hannahschannnel96366 жыл бұрын
Thank you!!! This made so much sense
@axlblazeauthor6 жыл бұрын
the video is seriously a great help
@booyah211 Жыл бұрын
Thank you so much for this explanation! It finally cleared out my doubts about this topic :D
@marlonrezash47525 жыл бұрын
Wow that was a great lesson! And in only 8 minutes!
@sahildhindsa8763 Жыл бұрын
EXCELLENT explanation. God bless you.
@zero-one3599 Жыл бұрын
If I could know you early... Your explanation is much simpler than any doctor... God bless u... thank u so much🥰🥰🥰
@simonsays50942 жыл бұрын
This is awesome! my lazy orgo professor keeps teaching half the material we need to actually understand stuff and then starts randomly talking about things she never bothered to explain. EWG and EDG are one of those examples and today she just started throwing those phrases into lecture out of nowhere.
@archanamujumdar16764 жыл бұрын
Thanks a lot for this wonderful explanation.😃
@anushkasaxena52574 жыл бұрын
Thank You So Much..this really helped me!..keep it up!
@Daxdikooo5 жыл бұрын
Thank you so much, you made my day.
@kukatlanandithayadav906 жыл бұрын
Thank you soooooo much.. M preparing for medicine entrance it helped me very much to understand the other topics ..love you!! 💓
@iTechProductionsmh13 жыл бұрын
THANKKK YOUU FROM THE BOTTOM OF MY HEART 🥺❤❤
@kalkidanberhanu77083 жыл бұрын
Wow this is so clear thanks!
@abhilashsahu92404 жыл бұрын
Excellent explanation . Thank you ma'am 👍🏼👍🏼
@NgocMyNguyenThi-bk9it2 ай бұрын
extremely helpful, thank you, ma'dam
@monaabdelkareem57094 жыл бұрын
thank you very much your explanation is amazing
@nourseenajamy73 жыл бұрын
Extremely AMAZING..
@madelainerose55582 жыл бұрын
Omg I freaking love you. Thank you so much for this video. I think I am only going to watch English content from now on for studying because these videos are so much more helpful than the German videos that are on KZbin 😂
@lamiahsalim22333 жыл бұрын
Thanks a lot!!! This video literally saved me from memorizing these groups using acronyms....😜
@tasneemmousa48105 жыл бұрын
Thank you! Perfect video
@officehubk88824 жыл бұрын
Thank you very much mam before seeing your video i was. Nothing in chemistry but now i have mastered
@kiranpandey62314 жыл бұрын
Thank u very much mam really you cleared my biggest doubt.....😊your videos are really helpful....lots of love from India
@kenmagee86906 жыл бұрын
I have never made a comment on a video before, although I have given thumbs up or down. EAS was kicking my butt and I was so frustrated not being able to figure it out. Thank you so much for this video........
@MolecularMemory6 жыл бұрын
Thanks for leaving me a note! I'm happy to hear my explanation helped you.
@zamanmakan27293 жыл бұрын
Couldn't find a better explanation :), thank you! But briefly, how do you explain the difference between induction and resonance?
@idonthavethink1825 Жыл бұрын
Love you for this
@karunyareddy14582 жыл бұрын
Wow absolutely helpful 👍.
@miaricciardi-kling95826 жыл бұрын
Thank you so much for this video you explain the topic so well.
@user-qo6fp8ej2i6 жыл бұрын
This is soooooo useful..... Thank u so much!
@shanemichael90115 жыл бұрын
Been studying orgo chem on spare time (odd as that may sound) for the past couple of years. This video was very helpful providing an easy way to remember the EDG and EWG on Benzene rings. And in this subject, memory recall is very important. Thanks !
@devarajuppuluri5012 жыл бұрын
U clarify my unique problem
@jayeshsonawane1890 Жыл бұрын
It's really helped a lot to me thans ❤️
@zaheenanwar79475 жыл бұрын
Best explanation
@indian46165 жыл бұрын
Thank u a lot.. it helped me!
@rohitpyngottu60665 жыл бұрын
Nice. well done
@mousam87195 жыл бұрын
Thanks. ...that was useful. ...😊
@atenalbert75766 жыл бұрын
Thank you so much !
@rangakumarithota54084 жыл бұрын
Nice explanation 👌👍 thank u 💐😄
@humezafirdaus82115 жыл бұрын
Superb!!!!! 👌👌👌
@HJ-wm8qi3 жыл бұрын
Thank you so much.. I really have a tough time to memorise those EWG EDG and ortho meta position since I don't understand the concepts...Tqvm
@bhadragiri58026 жыл бұрын
U cleared all my doubts....😘😘😘
@vasumongam49364 жыл бұрын
Extremely helpful mam thank u
@rajsanap8423 жыл бұрын
Thank you💗
@777osbaldo13 жыл бұрын
Nice!
@garima__sri3 жыл бұрын
Thankyou so much🙏❤️
@iamDBK5 жыл бұрын
u saved me.....thank u so much
@alexlu69204 жыл бұрын
Thank you for explaining the concept so clearly. However, can I ask about just a halogen bonded to the benzene? It’s electron donating (so ortho para directing) but yet it weakly deactivates the ring.
@MolecularMemory4 жыл бұрын
At the end of the video, it links to a follow up video, which has just the information you're looking for. Thanks for watching!
@ritubisht20483 жыл бұрын
Tnq so much it helpd
@slendrmusic2 жыл бұрын
Thanks!
@gauravsuyal44565 жыл бұрын
Love from india...
@ryngkatdohtdong14085 жыл бұрын
Please make a video about +R and -R effect
@savage-xx8hh3 жыл бұрын
It clear ,all my doubt love u from my heart❤️❤️❤️❤️❤️❤️❤️❤️❤️😓
@kyunki37963 жыл бұрын
nice one
@panguluri1006 жыл бұрын
very nice video
@ilyassalmon95134 жыл бұрын
thank you
@vamsikrish24 жыл бұрын
Please try to make a video based on ELECTRON MIGRATION effects..
@nomadgamercao11775 жыл бұрын
Ma'am methoxy is given as EWG in my textbook.....is there something wrong in my text??
@gbpunjabi53013 жыл бұрын
It's perfect
@BiswajitMondal-ne1cq4 жыл бұрын
first you said that EWG is meta director but in your example (A) that was EWG but you show that is also para director if i say any wrong then please explain me that portion
@mbibi6 жыл бұрын
Awesome thank
@akhilareddy96482 жыл бұрын
Tqqqqq soooo muchhhhhhh😘😘😘😘
@juneddadel93695 жыл бұрын
thank u miss
@atmadeepsen48543 жыл бұрын
Thank you Molecular memory 🙏
@Qwerty-qm4yt6 жыл бұрын
Can u tell me the expansion of octet??
@dhruba60442 жыл бұрын
Thanks
@jatindervirsingh485011 ай бұрын
nice
@Diana-xm8ib6 жыл бұрын
excellet!
@jeeaspirants21613 жыл бұрын
Mam your voice i like it👍 And also you teaches best ❤️
@vedant80023 жыл бұрын
You English best
@Devraj-ny5bc2 жыл бұрын
what happen if y is -ve ly charged ?
@userr_aa3 жыл бұрын
masha-Allah how can this amazing teacher explains this just within 8.09 minutes? omg you're so blessed..thanks a lot!! your video is very helpful. I wish you have a great day! I was like 'thank God, I met her'
@Brilliance532 жыл бұрын
Wow you are a good girl 😜🙂
@abhinavm96856 жыл бұрын
Thanks a lot 😃😃😃
@snehad92244 жыл бұрын
Mam wt abt OAc group and Och3 group
@namjoonpark53093 жыл бұрын
Finally!
@winnielygamer6 жыл бұрын
Where is the follow-up video about the strengths of EWG and EDGs? :o
@MolecularMemory6 жыл бұрын
I still need to make this one! Thanks for watching!
@SarthakKumar5 жыл бұрын
Will it work only when we do Electrophilic aromatic substitution?
@MolecularMemory5 жыл бұрын
The directing effects are for EAS. However, this analysis will work to tell you if any group is electron donating or electron withdrawing. Thanks for watching and leaving me a question!
@zehragulsever8566 Жыл бұрын
Why EWG is ortho-para directing? did we say not EDG are ortho-para directing? EWG should be meta directing.. ı am confused
@nish94218 ай бұрын
Wow.
@vashishtcreations32446 жыл бұрын
please made video on inductive or mesomeric effect
@MolecularMemory6 жыл бұрын
This is a great idea! I'm looking for ideas of what to do next and I appreciate your comment.
@vashishtcreations32446 жыл бұрын
Molecular Memory ..... thanks dear 😊😊
@lavishkumar35953 жыл бұрын
If Y is more electronegative then Z it is electronwithdrawing group and if Z is more electronegative than Y then it is electrondonating group i think this is the right one
@spacex9364 жыл бұрын
♥️♥️♥️
@devadharshini90694 жыл бұрын
What about HC=O ? EN of C is less than O but more than H
@MolecularMemory4 жыл бұрын
The oxygen wins here, and aldehydes are EWG. Hydrogen is less electronegative than carbon, but just slightly. Hydrocarbons are considered to be nonpolar, since the electronegativity difference between C and H is not very much. Thanks for a great question!
@easwaramoorthythiyagarajan59415 жыл бұрын
👏👏👏👏
@raht95785 жыл бұрын
Wow
@avinashsharma57415 жыл бұрын
Maximun edg in following 1 -coNH2 2 -NHCH2COCH3 3 -NHCOCH3