Depression: (The Dark Side Of Wellbutrin/Bupropion)

Major depression has afflicted humankind since time immemorial and has caused, and continues to cause, immense morbidity and lost hours of work worldwide. Depression is a common condition and can have more serious consequences, leading to other mental conditions that can have fatal outcomes. Studies have shown that depression affects the likelihood of survival after heart attacks and strokes, as well as the degree of control of diseases such as diabetes and HTN. Fortunately, we have an extensive selection of medications to manage depression, but many of these cause side effects that are intolerable to patients or fail to relieve symptoms completely. Wellbutrin (bupropion) is one of the medications used as an alternative or adjunct to failed treatment trials, and many patients have derived relief from Wellbutrin (bupropion). However, there exists a dark side to Wellbutrin (Bupropion) that many people are unaware of: the potential for abuse. In this video, we examine this lesser-known feature of Wellbutrin (bupropion).

[@Pavel1560]

I have history of stimulants and other drugs abuse, MDD, anhedonia, no motivation to get out of my bed. I tried snorting bupropion once (150mg tablet) and its nothing to compare with amphetamines or cocaine. High is unplesant and short acting, instead I just started to take bupropion as prescribed and this med changed my life in every aspect. No more depression, no more lack of energy and no more drugs craving. I'm on theraphy now, changed my bad habits and i feel optimistic first time from very long time.

[@DrKevinLowe]

That is truly a remarkable and inspirational success story! I wish you continued success on your journey to recovery. Thank you for sharing it with us.

[@Pavel1560]

@@DrKevinLowe Thank you so much!

[@GodfearingGuy101]

I've been on this medicine for at least 3 or 4 weeks...how long did it take for all the previous depression to wither away?? I've been taking this medication every day and it's gotten me up and active and happy and then some days down and sad ...

[@Pavel1560]

@@GodfearingGuy101 I've waited 6 weeks for full effect. It's normal to feel ups and downs at the beggining, but it should stabilize soon. If not you can bump your dose up or ask your doctor to add another med for better response. I'm also on low dose of mirtazapine (15mg) and it seems to work synergistically. Good luck!

[@yolo4dolo28]

Thankyou and congratulations

[@carolherm]

I believe these medications act differently on everyone. For me personally, bupropion was an answer to prayer. Severe depression lifted. I still have my days, but on the whole, it's worked for me. I wish all well.

[@DrKevinLowe]

Thanks for sharing.

[@brianwilliams6555]

That's true.. I abused many drugs over the years and I knew some pretty functional normal people that would do a couple hours of cocaine and will be on the ground with a gun like they were a soldier and going from one window to the next. And I've known people that can do cocaine and go to work and you never would know it. That wasn't me though. I'm glad the Wellbutrin help I'm thinking about getting on Lexapro I have an appointment tomorrow

[@JacksonianYT]

Lexapro 5mg has been amazing for 11 months and hardly any side effects 🙏

[@brianwilliams6555]

@@JacksonianYT How long did you feel a difference? I started 10 mg today

[@deborahgardner2446]

I start this antidepressant in the morning. Wish me luck 😃

[@xXx___xXx]

I've been taking Bupropion for depression and ADHD for 3 months and it doesn't give me any side effects. I naturally have really low blood pressure, so the fact that the drug increases it is actually beneficial for me. Previously I tried 3 different SSRIs and they all gave me emotional numbness, constant nausea, sleeping problems and lack of sex drive. I guess you just have to try antidepressants from different groups and find a good match for yourself.

[@DrKevinLowe]

Thank you for sharing your experiences with Bupropion and SSRIs; other viewers will benefit from your insights.

[@ashuvijay7031]

Escitalopram and clonazepam gave me horrible sexual side effects ! Should I try wellburtin ? I just have lack of energy fatigue due to my past depression ! I don't have any Panik attacks or deep depression ! Just fatigue in my body with sexual side effects of clonazepam and Escitalopram. ! R u still taking it ?

[@xXx___xXx]

@@ashuvijay7031 yeah, I'm still taking it and feel really good, finally able to function normally and not rot in bed all the time. My sexual drive is normal on Wellbutrin. I took escitalopram as well, it was the first drug for depression that I got prescribed and it gave me sleeping, eating and sexual side effects. The only side effects of Wellbutrin I've observed are that my skin got slightly more oily and hair gets greasy faster. Also, SSRI drugs just made me really numb, helped with depression but I couldn't function normally, so I was just my depressed self unable to complete daily tasks, but didn't feel so bad about it I think that wellbutrin could be a good match for you, cause it mainly gives you energy and motivation, but doesn't really calm you down if you struggle with anxiety and such.

[@jan4222]

I was put on Wellbutrin after my husband passed away. It kept me in a deep, dark hole for an entire year. I weaned myself off, and the darkness lifted and I actually felt like living again. No more for me, thanks.

[@DrKevinLowe]

Hi Jan4222, I’m sorry to hear about the bad experience you had. As you know, it doesn’t work the same in everyone. I’m glad you’ve recovered completely. Thank you for sharing.

[@doug5372]

Sounds like it got you through the depression ?

[@jan4222]

@@doug5372 I would say the opposite. I didn't care if I lived or died or woke up in the morning. It was more than losing my husband, which was (and is) bad enough. I was drowning in darkness. The longer I was off that poison, the better I felt.

[@meganelizabeth7818]

@jan4222 may i ask what milligram you were on?

[@jan4222]

@@meganelizabeth7818 I honestly don't remember the dosage. If I find it I will let you know!

[@2healingminds147]

It was not good for me and had a negative effect.

[@camellia8625]

Wellbutrin the only medication for my bipolar 2 which hasn’t had upsetting side effects - no weight gain, no lethargy, no reduction in libido. Have been on it now for over a decade without issues. Every person is different. Suspect I have atypical bipolar 2.

[@DrKevinLowe]

That’s wonderful to hear that it worked. Thanks for sharing.

[@nancylo188]

Have u ever experienced breathing problems..or ur heart pounding harder just to walk up steps

[@DogMommy.]

I been on Celexa for a 1 year now and it's ok . I just don't like the weight gain . Thinking of trying to switch to wellbutrin

[@the_velvet_void]

Experience hairloss during that time?

[@blossom.583]

yes, it is happen with me​@@the_velvet_void

[@leannawhetton6328]

I have struggled with addiction since adolescence including a coke addiction. I started Wellbutrin 6 months ago for depression. It has helped me quit smoking cigarettes and reduced my coke cravings. I am now 6 months sober and cant remember the last time i had a drug craving. This drug literally saved my life my depression is under control and i am working with an addiction counselor to help maintain sobriety. I dont think i could have done it without this med.

[@DrKevinLowe]

Congratulations on achieving and maintaining sobreity! I have seen patients struggle to achieve what you have done. Do not dismiss the role your own strength and resolve played in helping you reach your goal. Wellbutrin was just a tool you used to get there. Thank you for sharing with the community. I wish you continued success in the future.

[@aizazhashmi9433]

I was diagnosed with MDD 8 years ago, taking SSRIs since then a month ago I started taking bupropian 300 mg. It has increased my motivation for study because I am engineering student and have lots of stress.

[@DrKevinLowe]

Hi Aizaz, I’m glad to hear of your success with bupropion. I wish you continued success in your studies. Thank you for sharing.

[@desperion5250]

Aizaz, which SSRIs do you take?

[@aizazhashmi9433]

@@desperion5250 I take Escitalopram 20 mg in the morning. I have been taking it since 2015. Initially, I was prescribed 10 mg.

[@aizazhashmi9433]

@@desperion5250 I had also taken flouxetine, sertraline but they hadn't any effect on improving MDD

[@kobebryant-cl7ul]

Any side effects like anxiety or irritability? Does it feel like a stimulant to you? Any side effects like increased pulse or high blood pressure?

[@elisefincher4478]

I was on this for about a year and it was horrible. My anxiety was through the roof, I had extreme trouble sleeping and had increased vivid nightmares and had constant jitters. It was not a good experience and I’m glad I’m no longer on it.

[@DrKevinLowe]

I’m sorry to hear of the adverse experience you had. Unfortunately, medications act differently in patients. Some people are better able to tolerate medications from specific classes than others. Your shared experience will help inform other viewers. Thank you for sharing. I hope you were able to find a more tolerable medication, and are now doing much better.

[@diegofiorillo6412]

Same for me, o have it a week and couldn’t do it any more. I felt like I was losing my mind

[@DrKevinLowe]

Sorry to hear that. Ditto as above. There are other options that may be more suitable for you. Thanks for sharing. Thanks for watching.

[@DrKevinLowe]

Sorry to hear that. Ditto as above. There are other options that may be more suitable for you. Thanks for sharing. Thanks for watching.

[@Lilmommyoflove]

This video was not about side effects. It was about addiction

[@KevinKans]

AND! So you work for the companies or something or a wacked out humanist!

[@NXNX]

i personally have been suffering from post ssri sexual dysfunction (pssd) for almost a decade after a 10 month treatment with citalopram. i know many people who suffer from post ssri syndrome in a more severe form than i do, i.e. with symptoms of emotional dulling and anhedonia and cognitive dysfunction. there are young people among them who have taken a drug for all in all mild problems, and not severe depression or mental disorders. I wonder how a doctor can be honest about this and continue to prescribe these serotoninergic drugs in abundance, which are also becoming more and more widespread off-label. and how can a patient really assess the risk-benefit ratio before prescribing, as long as there is no epidemiological data to tell how widespread the risk of PSSD is and doctors continue to fail to inform before prescribing, and even to deny the harm done.

[@DrKevinLowe]

@N X I understand your concern, but usually a doctor would inform his patients of the potential side effects of a particular medication to avoid any surprises. That way, you can make an informed decision as to whether you want to take the medication.

[@brianwilliams6555]

@@DrKevinLowe it's sad but when it comes to psychiatrist I would rank them near the bottom when it comes to explaining side effects or even explaining the diagnosis to the patient. I've had much better experience with a Family Physician when it comes to good bedside manners and explaining the medications. If psychiatrist had the mannerisms as Dr Lowe we be in better shape!!!

[@susanmorgan4151]

Agreed!!!

[@JEBBY123IFY]

It's called big pharma $$$

[@NathanDeger]

My sex life has forever changed because of prozac. Hope it gets better but it seems like it's permanent.

[@VanessaSimon26]

Wellbutrin was awful for me. Anxiety through the roof. I am glad it works for others.

[@vizagitywaltair]

😢😢

[@vizagitywaltair]

Did you stopped taking it?

[@ICantthinkofahandleforme]

My doc prescribed me Ativan for the increased anxiety at times. I definitely get waves of it but it evens out ultimately

[@Arise1337]

Exacly same for me. I was feeling much much worse after it

[@rachelfishbein1478]

Same. I also had a pretty bad case of OCD while on it. I stopped taking it last week after 6 months with the goal of managing ADHD. Clearly it didn't help. Too much norepinephrine in my brain resulted in me reacting to the most mild critiques and disagreements as if I were being attacked by a bear. Took a few days to completely leave my system, but once it did I felt so much better. I'm disappointed in my doctor for downplaying the anxiety risk. If you already struggle with anxiety, I would say Wellbutrin is not for you.

[@mr.marvelousmess6986]

I am thinking of getting off because of risk of dementia/Alzheimer’s. Anybody else worried?

[@gloriajuarez7520]

Im scared for that

[@Thegoldenchild2020]

Yes I'm throwing all this shit in the trash hell now I'm a control my damn anger and depressikn read books watch motivation vieoes take long walks etc yesterday was my last day taking any medicine

[@susanmorgan4151]

Absolutely! Dementia runs in my family- don't want to add to the possibility...

[@tinaredd6858]

Wait whattt

[@Mmcermes]

My memory is funded up by both bupropion and alprazolam

[@Acemechanicalservices]

An effect similar to crack? Anyone who claims that has never smoked crack.

[@travisjames3132]

Damn Right! 😂😂😂

[@anglophoned]

It’s good but i get so fkin angry

[@susanmorgan4151]

Same!

[@Pine_bluffs]

Same

[@alexalexandersen5198]

😂❤

[@D.T326]

Same

[@georgetsipas49]

Same

[@whytho1952]

I have a history of opiate and amphetamine addiction.. primarily opiate… I was addicted to heroin for about 10 years and later on in there I started dabbling in amphetamines.. I am currently taking Wellbutrin after taking it for a year and a half then not taking it for a year and a half … now I’m back taking it… I wanted to come off just to see how it would go.. it went fine and it has actually reduced the amount of cigarettes I smoke from almost a pack a day to 3 a day or sometimes only 1… but I’m still an addict so that one is tuff to drop… but I am literally about as much of an addict as a human can be.. not proud just a realist and this drug has helped me in so many ways and I’ve never felt the urge to abuse it. After doing heavy drugs I honestly cannot see how this drug would ever even be worth abusing.. it’s so subtle which is what I love about it.

[@DrKevinLowe]

Hi, thank you for sharing your experiences. Thanks for watching.

[@KevinKans]

You have the greatest gift of life given to you in the whole Universe. It is your OWN FREE WILL! Use it wisely and choose to do right. You have the power already granted to you anything else is just an excuse no matter how you package it. Don't trust these Humanist's and their Devilish drugs. Make that choice to say NO! That is the greatest gift that God gave you from birth. If you can grasp that truth there is nothing that can stop you.

[@sinniedagoat]

@@KevinKansso what do you say about the people who need medication to LITERALLY stay alive?? Or the meds that keeps peoples transplanted organs from failing? Or chemo for cancer ? Hm?? Is it different then??

[@sirtom14]

Took Wellbutrin around the start of this year and almost immediately developed severe tinnitus. I quit cold turkey after a couple of weeks but the ringing persisted. It's been steadily improving since, but if I knew my life could be so negatively impacted by this drug I would've stayed far away from it. Antidepressants are often handed out as a first line treatment without even considering the patient's lifestyle factors that could be making them depressed. After this experience I refuse to ever take psychiatric medications again.

[@DrKevinLowe]

I’m sorry to hear that. Thank you for sharing.

[@Minincognito]

I can relate. Very frustrating :(

[@Mmcermes]

With antidepressants and drugs in general the profit is easy.

[@jdssurf]

i got tinnitus off and on too, major neck tension and so forth, 10 days and i quit, no thanks.

[@onefortrees]

Y’all are in the 1-2 %tile. Hope y’all recover.

[@calidecali]

Took Buboprion for about 6 months and felt pretty good at first. Helped my social anxiety. One thing ive never heard doctors talk about is the possibility of the medication raising your testosterone. I was always hot and aggressive, excessive sweating and high blood pressure. When i took a testosterone lab test my test was 877. Im 38m

[@erikthechosenone]

I just got my Bupropion HCL 150 MG filled today. I have my bottle in my hand now. I have yet to take it. Hopefully this doesn’t happen with me. I’ve heard really great things about the medication.

[@DrKevinLowe]

Hi CaliDeCali, I came across one study in laboratory animals suggesting that bupropion may raise testosterone levels. Studies performed in animals do not confirm findings in humans. Besides, other studies found no evidence that bupropion raises testosterone levels. I think you need to get evaluated for other causes, just to make sure. Thanks for sharing.

[@nikk5002]

The excessive sweating is the reason I stopped taking it. It was very noticeable hyperhidrosis. Other than that, it was a perfect medication for me.

[@blitzboring9996]

I’ve had to be on spironolactone (testosterone blocker) since I got an bupropion Because my acne and hair loss got out of control I’m almost positive that it was from the medication. But since I got on those two medication’s I have never felt better.

[@RS-zl4vs]

@@erikthechosenone what happened now ? u took it for 2 weeks? bc i got diagnosed with major depressive disorder so is it gonna cause that ? also i wanna get my driving license after a month & half, will it be dangerous to drive while taking it

[@jdssurf]

i couldn't get past 10 days, was horrible, watch out for long lasting tinnitus too

[@SynchronousFailure]

How's your tinnitus now?

[@jdssurf]

@SynchronousFailure it went away in a few days, it was like little bouts of it about 30 seconds at a time. The stuff made me feel crazy, couldnt find my words, weird fog, higher heart rate, felt like everyone was staring at me, full anhedonia......all was better after stoping for 2 days

[@SynchronousFailure]

@@jdssurf Super glad to hear!

[@MrEcm51]

It gave me tinnitus, plus aggressive uncontrollable anger. Worst stuff ever!

[@pegsutton8438]

Yes, tinnitus here too .. and high anxiety

[@izer2024]

It cracks me out and makes me stay up all night getting only 1-2 hours of sleep. Even breaking them in half. This medicine sucks

[@RagingDamage]

Bro that happened to me for a week but after the first month or so I started sleeping better. I even asked the doc to give me something to sleep and by the time I even picked up the script I started having higher quality sleep. Stick it out.

[@optical76]

I’m only a week into the xl version. Noticed slight anxiety at night but enough for me to struggle falling asleep. I’m extremely sensitive to melatonin so I take 1mg childrens gummy an hr before bed and it completely solved any issue of falling asleep. I’ve slept good 3 nights in a row with continuous 6hr of sleep which is my normal sleeping time. Maybe try that or 5mg adult melatonin?

[@izer2024]

@@RagingDamage I’m trying. Let’s hope it gets better.

[@izer2024]

@@optical76 I take adult melatonin but it seems to cancel it out. Sticking it out though so we’ll see.

[@honeysingh-og7dw]

My mom just started taking it to and is facing insomnia, she's on week two

[@novembersrage3335]

june 26th 2020 i overdosed on wellbutrin i was abusing when i couldnt find adderall from a dealer. i had back to back seizures and was intubated for 2 weeks. i was 17 then with a terrible addiction that shoudlve killed me. now im pushing 20 in a 2 weeks and im 2 years sober. its possible yall believe that

[@DrKevinLowe]

Congratulations on your success story. Many people can learn from your experiences. Thank you for sharing.

[@susanmorgan4151]

Thank you.

[@Lafuma99]

When you abuse it does it show up as amphetamines on a urine test let me know please cause I have to UA for DOC tomorrow

[@AngelinaX23]

When Wellbutrin was still an American made, non-generic drug, it was a terrific CNS stimulant and mood enhancer. It helped me work more efficiently and also to look and feel better. When the patent ran out and the generic versions were the only thing available, it was like a prescription placebo. It literally did nothing except waste your co-pay every month. I was off of it for a decade, but I recently tried it again after my daughter was murdered by her fiance. The generic Wellbutrin (bupropion) isn't even made in the USA anymore. It's made in India! Out of desperation I took it anyway. Within 10 days I developed chronic migraines, anger episodes, unalive ideation, and severe joint pain. I felt like I had been poisoned. I would rather be depressed than have that garbage in my body.

[@DrKevinLowe]

I’m sorry to hear that. I hope you were able to find a suitable alternative. Thanks for sharing.

[@jdssurf]

i only tried generic, it was awful.

[@NotSoNormal1987]

I've tried a few different generics at this point. And the more oval/oblong white tablet was like taking a placebo. (It has the number 145 on it) I had a month where that generic did nothing for my mood, before getting a different and actually effective generic. Pharmacists and drug companies like to try and say that generics are all the same. But that has not been my experience. The fda doesn't do enough to make sure all generics are up to standard. I have even been given a generic adhd medication (supposedly a generic for concerta.) That I later found out the fda had pulled from the market, because it was proven to be way less effective. A low quality generic can make for a very hard month. I've lost too much time to mental illness. And I have lost too much time to poor quality generics.

[@nenadcubric2663]

It could be, that your Body dont respond to the drug like it did the first time, that happend to me with 2.5mg Olanzapine,

[@DaddyWarbucksunlimited]

All drugs are a crapshoot at best. Everybody's system inside their Body are unique to themselves.

[@susanmorgan4151]

Truth.

[@KevinKans]

That is a complete lie! Regardless it damages the system in different ways. Stop sucking on the Bottle!

[@erikthechosenone]

I just got my Bupropion HCL 150 MG filled today. Since this mediation has a black box warning. I have to meet with my Nurse Practitioner every month. I have my bottle in my hand now. I have yet to take it. I’ve heard really great things about the medication. I got it prescribed for my depression, but especially for my ADHD. I’m hoping it does great things for me. Considering I’m not hyper, but I have a difficult time focusing and concentrating on this. I procrastinate a lot. I start wayyy to many projects that I don’t finish. With my ADHD it’s like this: Imagine being in a gymnasium with hundreds of thousands post it notes on the walls. On every post it note, there are thoughts, tasks and projects listed on them. That’s what my mind is like 24/7. The projects, thoughts, ideas and advice are really great. It will definitely benefit my life and progress me further. But I just cannot even go through step one and sit down to focus. I get so distracted easily. It’s horrible. Hopefully this medication will really help me!

[@DrKevinLowe]

That is a very vivid description of what you are experiencing. I sincerely hope the medication works for you. Thanks for sharing.

[@nakeyiathomas7882]

I didn’t know how to explain how I was feeling but you hit the nail on the head with this one 😂 my mind is trying to focus on all these great things I want to do but I can’t begin because I can’t focus on that one thing. I’m trying to focus on 2000 things at one time and getting nothing done. Then beat myself up because I’m getting nothing done 🤦🏾‍♀️

[@erikthechosenone]

@@nakeyiathomas7882 Are you going on medication too?

[@strawhatpirates4]

How’d it go?? Starting it for the same reasons

[@erikthechosenone]

Wellbutrin made my heart beat faster than normal and sometimes I would get heart palpitations while being on it. It definitely was not fun while working out. I am on Lexapro now, but the Wellbutrin did help me quit smoking, when I did smoke it tasted horrible and my body would reject nicotine which was pretty cool. Since Wellbutrin is a smoking cessation. I can definitely say I only wish I was still taking it to help me focus. But after taking the wellbutrin i kind of am permanently in a state where i can somewhat still focus and actually come to terms with what i need to do in terms of motivation. @@strawhatpirates4

[@brittanyguerra602]

My dad switched to this from Fluoxetine because he wanted the the added benefit of not smoking. He killed himself without warning within two weeks of the change. Be careful 🙏

[@DrKevinLowe]

That’s a very sad story. Thanks for sharing.

[@bsbrum]

I am so sorry, Brittany. My son, an Army vet, was given Bupropion on April 4, 2023. On April 5 he took his last photos, an avid photographer. He took his own life, completely surprising everyone, on April 13. 8 days. He went from mild depression with ZERO suicidal thoughts, to dead in 8 days.

[@brittanyguerra602]

@@bsbrum I am so sorry! A parent should never experience the pain of losing a child. My heart breaks for you. I talked to my dad 7 minutes before. He was fine, laughing and told me he would see me that Wednesday. April 2022 Elon Musk tweeted “Wellbutrin is way worse than Adderall imo. It should be taken off the market. Every time that drug has come up in conversation, someone at the table has a suicide or near suicide story.” He got so much bad press for saying it, but he is right. Studies outside the US show the truth of its links to suicide. The test groups are ridiculously small. These doctors should wear patches on their lab coats like race car drivers showing which pharmaceutical companies fund them.

[@bsbrum]

@@brittanyguerra602 i could not agree more. Did you know that because the DEA has classified Bupropion as being low risk for abuse, any primary care provider in all 50 states can prescribe it!? A nurse practitioner killed my son with it. He went in for physical therapy and left with a death sentence.

[@bsbrum]

@@brittanyguerra602 this comment thread is not the place to ask you what I want to ask you. Can we talk?

[@sheilabrennan4481]

I have been watching several youtube videos by various doctors on this medication and have never heard it has similar effects as cocaine (nor the various street names you list)... in high doses you state. It would be helpful if you gave a range of what might be considered a high dose. I am familar with the risks of seizures and other possible side effects. Thank you.

[@DrKevinLowe]

Hello sheilabrennan4481, when it comes to medication, anything above the recommended dose is considered a high dose. If you’re taking a dosage at the upper limits of normal, that too can be referred to as a high dose as opposed to a lower dose. Like all medications, Wellbutrin could be and has been a miracle drug for some, whereas, for others, it could be the source of severe side effects. Of course, if the medication is abused, the likelihood of side effects increases significantly. Thank you for watching.

[@aaronjones6238]

Bupropion worked great for me for a long time, but I still had some residual depression from seasonal changes that were hard to subside. My doctor added prozac, and for sure I became way less depressed, more energy, huge increase in memory. The side effects however, were unbearable, I was waking up earlier and earlier each morning until finally I started waking up at 2am unable to go back to sleep, shakes/chills, jaw clinching, and horrendous GI issues. After a month of this, I finally had to toss in the towel, despite it working great for my depression and anxiety. This is the concerning part, after ending the prozac, my insomnia didn't go away, and my wellbutrin is now causing nervousness. Now I'm having to stop both... we'll see how it goes

[@DrKevinLowe]

Hi Aaron, I hope you find medication that works for you soon. Thanks for sharing.

[@EdBender]

Try melatonin for prozac abstinence insomnia. It works.

[@TheCoolOwen]

Wellbutrin was like a sugar pill for me, not addictive at all.

[@Kierracraftsndesigns]

I took Wellbutrin for 3 days and now I have hives, chest pain and right side neck pain. It was atrial for the right Med for ADD. Now taking Zyrtec and Claritin

[@DrKevinLowe]

Sorry to hear that Kierra. Please see your doctor as soon as possible. Thanks for sharing.

[@Allsmilelovee]

I got prescribed to Wellbutrin to help me quit smoking (I still smoke). But I stayed on it because it helped my depression A LOT!! The bad effects I get is I get irritated for small reasons.. I snap at my family; it’s like I have a shorter fuse. Also I “zone out” just stare off into space while someone’s talking to me and I’ll even say “uh huh”, “oh really?”, “Yeah”, etc.. then I snap out of it and say “sorry I zoned out, will you repeat what you were saying?” 🤦‍♀️ But I like it overall because it improves my mood, helps me deal with stressful situations so much better and helps my depression.

[@DrKevinLowe]

Hi Allsmilelovee, Wellbutrin has certainly helped many people with multiple complaints.I'm glad it has had a positive effect . Thanks for sharing. Thanks for watching.

[@asasso791]

I relate to zoning out but tbh I’m not sure if it’s the drug that causes it. I feel like it could be the case that wellbutrin made me notice it more when it happens instead of it making it happen more. I think it might even be thinkable that I was constantly zoning out before but because it starts to subside now I notice it because my focus shifts. I’m at my second/ third week 150mg per day. So far I noticed that everything feels a bit off. Also I have some weird feeling of nervousness without being nervous (I know that sounds stupid but I cant describe in any other way, it’s kinda physical but there’s this weird sensation of pressure in my abdomen too) All in all it’s awkward but my head seems somewhat clearer, I am less emotional in situations that I would normally be inappropriately emotional in. Etc. … I need to give it some more time and see what happens along the way

[@bullmoose6739]

I turned into a fat slob when I tried to quit bupropion. I had no impulse control. Gained 20 pounds in a month.

[@DrKevinLowe]

Sorry to hear that. But, I hope you are discussing your experiences with your prescribing doctor. I wish you all the best.

[@bullmoose6739]

@@DrKevinLowe I decided to go back on it and lost all the weight I gained. There’s so many benefits to it. Quitting the medication didn’t reduce my anxiety. I think I’m better with bupropion. 150 is ideal, 300 is too much. I just need exposure therapy. If I constantly avoid what makes me nervous, I won’t get better no matter what medication I’m on.

[@TxmmyBeats]

Long story short, ever since last year I’ve had a strange feeling in my chest, shortness of breath and tingling hands. There have been 2 times in the last year where I thought I was having a heart attack and 1 of them was when I was driving. It scared the shit out of me. Went to the doctor and my EKG was good, but my blood tests say I have high cholesterol and low vitamin D. My doctor thinks this might be due to anxiety and depression (I don’t think I’m depressed) so I just got prescribed Wellbutrin and this comment section is making me nervous. Edit: still haven’t taken the Wellbutrin. Too many negative side effects

[@KnockOnWood-sw3iu]

What did you about the cholesterol ?

[@HigoIndico]

Did they test your ferritin levels? Why would they give you medication for depression rather than tell you to take some vitamin d and omega-3 for a supplement? That's crazy

[@SacredVisions-]

Just want to let you know the same thing happened to me stared in December I didn’t know I was having a panic attack 😢

[@TxmmyBeats]

@@SacredVisions- sorry to hear that :/ do you know why you were having it or was it random?

[@TxmmyBeats]

@@HigoIndico that’s doctors for you. I still haven’t taken the anxiety medication

[@alvelundin402]

Thank you so much for this. I am starting my treatment with Bupropion tomorrow and this was extremly informative. Great work!

[@DrKevinLowe]

Thank you for the compliment. I’m glad the video helped. Thanks for watching.

[@jcbanbury]

Update?

[@sakazukiakainu3671]

Update?

[@rumayorjulio]

I didn't really hear any side effects aside from the addiction that can happen with a ton of drugs. Idk why the side effects of seizures with underweight patients wasn't mentioned

[@DrKevinLowe]

Hi rumayorjulio, this video is intended to specifically address the danger of addiction. Thanks for watching.

[@SpicyBricy]

Thank you for the indepth information. I found you searching for Welbutrin side effects. It has been added in addition to an SSRI I'm taking for MDD. Initially, I felt better, but I'm still struggling terribly. I think I'm having negative side effects of brain fog & imbalance. Two falls now and a fractured wrist. I was so hopeful of this medication. :(

[@SpicyBricy]

BTW I have a psychiatrist consult set for Monday to start seeing instead of my pcp for this diagnosis & meds. Thank you.

[@DrKevinLowe]

Hello SpicyBricy, thank you for your warm comment. I am not sure if you meant that you have had two falls and a fractured wrist since starting Wellbutrin; but if that is the case, today is Friday here and waiting until Monday is taking unnecessary risks. I would advise that you call your caregiver immediately and let them know what you are experiencing. Falls can be very dangerous. Thank you for sharing.

[@x.poison.girl.x]

Of course it won’t cause weight gain, I can’t eat on it. :/

[@marymitchell126]

Wow I am a recovering addict, been prescribed Wellbutrin for years @ 450mg a day. I only wish it gave me energy that others are experiencing!

[@sakazukiakainu3671]

Update?

[@medweb8690]

I had to stop buproprion because I was experiencing tachycardia for prolonged periods. My rate would usually climb to 110 to 125 BPM at rest. Although my tachycardia correlated with the initiation of buproprion, it's difficult to attribute it as a causal relationship.

[@DrKevinLowe]

@medweb8690 thank you for sharing that information. Did your tachycardia stop after discontinuing bupropion?

[@fabiendamien82]

@@DrKevinLowei had tachycardia as well after three weeks of taking Wellbutrin. And yes it was gone after stoppage.

[@DrKevinLowe]

@fabiendamien82 , I’m glad to hear that. Best wishes for the future.

[@Deulsenia1]

Just left ER for the same thing, and I was only on it for 2 days. I will never go back on it

[@SuperCody888]

Wellbutrin gave me the worst intrusive thoughts.

[@DrKevinLowe]

I’m sorry to hear that. It’s effects vary from person to person. Thank you for sharing that information. I hope you found something more suitable.

[@cleverusername5129]

how long did it take for them to go away for you?

[@SuperCody888]

@@cleverusername5129 after a quit using it.

[@brianwilliams6555]

Something I'm curious about is the most prescribed antidepressants like ssris and snris help with serotonin and norepinephrine. From what I understand sexual pleasure and energy fall under the dopamine umbrella. So do these medications indirectly help with dopamine? Now this is probably a few years down the road but it sure will be nice when we can take a blood test for dopamine and the rest of our crucial chemicals that keep us happy and everything else they do. I want to understand it more because I do know our gut is real crucial as far as serotonin and the rest of the neurotransmitters and or neurons and please forgive me if my medical is a little off

[@DrKevinLowe]

Hi Brian, SSRIs and SNRIs do not work on the dopaminergic system in the brain. Bupropion does. It certainly would be interesting to do a blood test and get a read out of your neurotransmitter levels. That would introduce targeted therapy by guiding practitioners in which antidepressants they prescribe for a particular patient. Who knows what we will see in the future?

[@brianwilliams6555]

That's the most frustrating thing when trying to figure out which antidepressant to take because you don't know if it's your dopamine or serotonin or whatever how many other happy chemicals in the brain

[@DrKevinLowe]

@@brianwilliams6555 yes, let’s wait and see what they come up with.

[@adventure1887]

​@Brian Williams probably the biggest help is getting the gene site test to see what your body reacts with to narrow down the ones to try. It's test all of them. Made us realize we wasted years trying stuff that didn't metabolize.

[@Acemechanicalservices]

@@brianwilliams6555 Hasn’t anyone heard of the studies that prove depression isn’t connected to serotonin levels? It’s a big pharma scam.

[@Minincognito]

This medication immediately gave me awful unbearable side effects and the doctors kept gaslighting me that it wasn’t this medication..😢 This is what I have been experiencing (I did not experience before starting Wellbutrin) Unbearable mouth sores everyday Dry mouth, swollen tongue, jaw clenching and sore throat ‼️ Excessive sweating and heat flashes, I have to change my clothes in the middle of the night Decreased appetite and weight loss (I was already 104lbs when I started) Constipation and hemorrhoid Nightmares and Insomnia Tinnitus Eye Floaters The docs want to treat the symptoms or wait for my body to “adjust” but it’s been 3 weeks no adjustments and I’m extremely uncomfortable all the time. I rather be depressed.

[@JEBBY123IFY]

Don't let them gaslight you! Those are bad side effects! Try ketamine infusions

[@NotSoNormal1987]

Ugh. That's awful. I've been on meds that didn't agree with me before. And it is the worst. Don't let them gaslight you. And if you can, seek out a different doctor, or someone who specializes in psychiatric medication. I see an NP that specializes in psychiatric medicine. And he does a much better job listening to me than a regular doctor did. Having a practitioner that actually listens to you is a big deal. I hope you feel better soon.

[@Minincognito]

@@NotSoNormal1987 thank you 🙏🏼🙏🏼🙏🏼

[@aylex1974]

Highly dangerous some pt’s experience suicidal thoughts

[@nathantoney.1501]

I thought this theory of neurotransmitters has changed?

[@cakepop702]

Unfortunately my experience wasn't good. I used bupropion and noticed an initial increase in motivation, but over time It completely altered my ability to express empathy. I also became extremely combative. I could see a shift in my personality but I thought this side effect would diminish over time so I continued while it only got worse. I stopped before I lost the ability to rationally acknowledge this wasn't my normal behavior. I've experienced everything from opiates to stimulant medication like phentermine that acts on the same neurotransmitters and nothing ever caused such an extreme out of control reaction like bupropion did for me. *Not to say it won't work for others, this is just a cautionary tale of my experience, since it's supposed to be a mild antidepressant*

[@DrKevinLowe]

@cakepop702 Thank you for sharing your experiences with us. Other viewers will certainly appreciate your insight. Thanks for watching.

[@cakepop702]

@IssBugs-qt8ed That's interesting. I sought treatment to help navigate down regulated dopamine receptors that resulted from the discontinuation of long-term opiate medication treatment. After the two year withdrawal period, I never returned to what my normal baseline was prior (If that makes sense), but I would not call it depression in my case because I knew what was happening and why. The theory was bupropion could help, but overtime it just felt more like navigating your reality under a constant excess of norepinephrine, That was useful in some regard for physical motivation initially but trying to navigate your daily interactions feeling like your in constant fight or flight mode was not helpful and most likely a precursor to a manic episode according to the doctor, but who knows. Some people believe that it's a sign that the medication is working and that you're actually developing the ability to be assertive instead of passive, but I don't know that I agree I just know it is somthing to be aware of if people decide to try this, the new found irritability/aggression isn't always just a side effect that will go away if you stick with it and could impact your relationships & life in a negative way if your not paying attention. I don't have a strong opinion either way and I'm definitely not a doctor or someone qualified to really understand the intricacies of what's happening in the brain though so idk lol

[@NotSoNormal1987]

Huh. I did notice that I'm slightly less empathetic on the medication. But for me, it just means I'm less sensitive I think. And stuff doesn't bother me as bad. I don't ruminate on my own mistakes as hard or as long. And it is harder for other people to manipulate me. I'm sorry you had a bad experience though. I've been on meds that didn't agree with me before. And that's no fun. And I feel like this is another reason that more medications need to be researched. And we need to check for genetic factors that could help figure out what meds work best for which people. The whole trial and error thing is no fun.

[@jurgi1103]

AI could help maybe

[@Mr.Omnicide]

I’ve taken the maximum dosage nearly 2 years now and plan on quitting cold turkey. Doesn’t feel the way it used to and now I believe it’s worsened things.

[@DrKevinLowe]

Hi Elijah Singz, I'm sorry to hear that. It is always better to discuss these things with your provider before stopping a medication. Thanks for watching.

[@elocelo1461]

dont stop abruptly it can lead to more depression and suicide, you have to taper off slowly

[@Mr.Omnicide]

@@elocelo1461 I stopped cold turkey and been off since my first post and feel a complete difference. Life changing. Medications are like gangs, you get jumped in and jumped out. I’ve been on everything in the book including antipsychotics, & withdrawing from those cold turkey is hell. Wellbutrin is child’s play in comparison. Meds are not a long term solution for most people and pharmaceutical companies profit over most vulnerable foolish people like myself who get doped full of shit in inpatient psychiatric facilities. I am ANTI-meds .. God Bless you all.

[@KevinKans]

@@Mr.Omnicide Amen! They are all liars and use excuses to justify themselves.

[@roxannemua9350]

Doctors try to put me on Wellbutrin I had a panic episode after my ex boyfriend tried to killl me. Long story short I was out on Wellbutrin it gave me the most horrific stomach pain I’ve experienced I tried everything eating before taking it … nothing helped once I completely stopped my stomach healed . Thank god I don’t listen to doctors I am my own doctors it’s my body and I know what’s harmful and what’s not

[@missionimpossible143]

Hi how are you 😢

[@jcbanbury]

❤

[@Americanpatriot-zo2tk]

MDD most of those caused by environmental issues. I’m a registered nurse of 38 years and I’m telling you straight this medication might have its area to be used but my opinion you don’t get the same people are promised.

[@DrKevinLowe]

Hello, medications do not work the same in everyone; but, as you say, Wellbutrin has its place. Thanks for your observation. Thanks for watching.

[@Americanpatriot-zo2tk]

@@DrKevinLowe I absolutely agree with you that too because people have different reactions to medication’s best regards from the state of Kentucky.

[@DrKevinLowe]

Thank you. Best regards from New York.

[@markwmbrown]

Im about 8 weeks into buprophin and im getting more depressed and irritability. Im at low dose. Started taking it after i quit drinking a couple months ago. Not sure to get off this or try higher dose?

[@DrKevinLowe]

Hello markwmbrown, I'm sorry to hear about your worsening symptoms. In such situations, you should contact your prescribing provider ASAP and let them know what you're experiencing. Only they know your case. Only they can advise on stopping or increasing the dose. Thanks for watching.

[@davelospinoso9022]

Grand Mal seizure from 150xl. Lesson learned, diet and lifestyle change are much healthier than putting chemicals in your body

[@lindamastropietro4429]

For a few months, the Wellbutrin helped me immensely get out of my deep depression, but now my anxiety is severe, and the depression is slightly palpable. Also, I’m losing a lot of hair. (I’m BiPolar ll).

[@DrKevinLowe]

Hello thank you for participating in the conversation and making a valuable contribution. The best person to discuss such issues with, however, is your prescribing doctor. This discussion is solely for educational purposes. Your prescribing doctor knows your case better than anyone else. Thank you for sharing.Thank you for watching.

[@aSjksk]

One of my friends experienced increased irritability and impatience after taking a certain medication, causing him to smoke more cigarettes. After stopping the medication, he returned to smoking at a normal rate, but not as much as when he was on the medication. So, be cautious.

[@DrKevinLowe]

Thank you for sharing. I hope ypur friend is able to stop smoking completely sometime in the future.

[@BizKit167]

Wellbutrin caused me tinnitus that doesn't go away even after long time after stopping the medication

[@DrKevinLowe]

I’m sorry to hear that. Thank you for sharing.

[@susanmorgan4151]

That's a typical side effect. It takes a very long time to stop, but it eventually does stop

[@mrgoop.]

@@susanmorgan4151 do you know how long it usually takes?

[@oxfordborg1400]

@@susanmorgan4151 Please can you tell me how long? 😢

[@oxfordborg1400]

@@mrgoop.Did you know how long?

[@digxx]

Bupropion has a very loose binding as DTI. It is somewhere 80%. It is actually so low, that it is thought to play no role in the pharmacokinetics. Responsible for the effect is more the nicotinic antagonism+NTI.

[@kobebryant-cl7ul]

Can you explain in layman’s terms lol? What is DTI? What is the point you are trying to relay, if u don’t mind?

[@Mmcermes]

It's a very weak Dopamine transporter inhibitor and it's thought to act primarily on NE reuptake

[@jcbanbury]

​@@kobebryant-cl7ul😂😂

[@turboman4736]

Yeah f that 💩 that 💩 screw me up bad my life will never be the same again 😡🤬

[@dimka_dev]

Thank you for the warnings doc. Good video. I've been taking 150mg for about 6 months and overall it's been positive. I have a history of drug abuse but never abused Wellbutrin (just promised myself the day I started taking it that I would never abuse it). Small hallucinations plus restlessness here and there. But significantly less thoughts about suicide, more motivation, better appetite, more creative, quit smoking, more muscle (crazy!), and seemingly getting along with others better. I've made lifestyle changes as well, I don't want to glorify the drug.

[@DrKevinLowe]

@dimka_dev I'm glad to hear Wellbutrin is working well for you. Thank you for sharing that story. I wish you continued success in the future.

[@kobebryant-cl7ul]

Does it cause increased anxiety or feelings of irritability???

[@dimka_dev]

@@kobebryant-cl7ul I haven't noticed a change in anxiety but I'm also not an anxious person. It's helped with irritability but again, I'm not very irritable. Hope this helps

[@robertpetzold1620]

I think wellbutrin made me stop drinking alcohol. I'm on 150 XL once daily. Two beer made me feel like I was on eight. I was getting extremely tired on two beers so I stopped. Could this a a direct reaction from the Wellbutrin.

[@DrKevinLowe]

Hello robertpetzold1620, thank you for sharing your story with us. Wellbutrin does in fact decrease the tolerance to alcohol in some people. Drinking alcohol while taking Wellbutrin can cause impaired cognition and lack of concentration and for this reason should be avoided. Wellbutrin is widely used to treat addictions and in some centers is used to decrease the craving for alcohol. It is possible it really did stop you drinking alcohol. Thanks for watching.

[@selenasanchez7336]

I was so adjetated i felt crazy arguing with strangers. Beware!

[@Pine_bluffs]

Same! Very angry from this med.

[@MrEcm51]

Same! I experienced severe aggressive anger. I couldn’t control it.

[@georgetsipas49]

Same

[@adventure1887]

I'm on 300mg a day (2 150mg) for a month now and it doesn't seem to work, I might not metabolize it. Risks don't seem worth upping it higher.

[@DrKevinLowe]

People respond differently to different medications, so don't give up hope. Remember to review your treatment with your doctor. Thanks for watching.

[@Tra1tors]

give it some more time

[@kylemiller4999]

I've been abusing a Wellbutrin for almost a year now I started in jail and when I got out of jail had to go into rehab as a part of it so the Wellbutrin is literally the only thing I can do and it's not very fun it's pretty awful most of the time the only benefit that I get out of it is that sometimes I just need a break from sobriety so when I can do that it stops me from doing dumber things like going and smoking crack or whatever but it definitely is not nearly as good as any other drug it's pretty much the worst fucking drug on Earth

[@DrKevinLowe]

Hello, thank you for providing firsthand information on this topic. I think it will deter others from considering doing the same thing. That is very useful. Thank you for sharing.

[@sher575]

Increased hunger from me. Started on 150mg for a month, was a life saver~ now on 300mg & I'm constantly hungry!! I have a history of binge eating, so this worries me. However my mood & anxiety is significantly better....I'm on the fence about this one.

[@DrKevinLowe]

Hi Sheryl Kansfield, binge eating may sometimes be the result of anxiety and depression; so, it is possible that as these improve the binge eating will improve as well. Discuss this with your doctor. Thank you for watching.

[@susanmorgan4151]

Increased hunger for me too!😢

[@sher575]

@@susanmorgan4151 I'm approaching week 3 of the new dose, and it's a bit better, still have my moments tho. I also had a really low episode as well. Super down and hopeless ... Cried over everything! And I'm not a cryer. However, this too is starting to level out. Here's to hoping for the best, and I hope it levels out for you as well ❤️‍🩹

[@JEBBY123IFY]

Not supposed to take Wellbutrin if you've ever had an eating disorder!!

[@sher575]

@@JEBBY123IFY yeah, after some research I found that too... I had to go back down to 150mg dose~ 300mg had me unbalanced. I'm better now, I haven't had those peaks of hunger or emotion like I did w the higher dose. I'm just kinda *meh* right now. I'm sure I'm better than I was before starting, but it's frustrating when nothing seems to really do the trick. Always *trying* something new. I'm over that. This is why I didn't take anything at all for over a decade I might go back to that ~ what's the point of taking something when you're pretty much at the same level as before you started 🤷🏼‍♀️

[@sabreanna3178]

20 years of taking it and I stopped taking it and lamicital cold turkey. I feel like I don’t need it anymore

[@milanic7267]

I have been on wellbutrin for a month and have a buzzing in my head that I don't think will go away even if I stop taking it. the medicine. is there any hope

[@DrKevinLowe]

Please discuss any side effects you are having with your prescribing doctor ASAP. Only they can advise you on your medication. I hope you feel better soon.

[@Auggies1956]

I have been on b for over the years, 225mg once a day. I'm seventy-five and have been experiencing dementia-type physical reactions. I'm being evaluated by a neurologist who thinks I might have early-stage Parkinson's. Any connection between the drug and my symptoms?

[@DrKevinLowe]

Hello, Parkinsonian symptoms can be a side effect of bupropion, although it occurs rarely. You should discuss and side effects with your prescribing doctor. Thank you for watching.

[@InstrumentalArcanum]

Best medication I've ever tried for panic attacks anxiety. I take it along side with 400to600 l theanine. Tried quite a bit of different ssri's . Sexual side effects are a big factor for me taking a medication . I will take this over all the others. If something ruins your sex life why would anyone want to take medication for that ?

[@mochabeauty6052]

Recently prescribed Wellbutrin . Haven’t had a panic attack for years until today. It was sudden and severe I ran to the emergency room. My goodness it was the absolute worst! I will not be taking it anymore 😢

[@gloriajuarez7520]

This happened to me on the furst day too!! Then i stopped then im taking it again! Now its been 4 days an i been so tired an lzy an i get anxiety!!.. ima stopp too

[@mochabeauty6052]

⁠@@gloriajuarez7520 Yes, I told my doctor it had to be this medication because it was the only new one. He keeps prescribing it despite me stating the side effects. I’d rather be depressed than to have back to back panic attacks

[@KevinKans]

@@Shrimpfried-rice Improving your mental health is an EXCUSE!

[@joshm6683]

It increases anxiety and depression substantially in most people

[@GrannyGooseOnYouTube]

​@@joshm6683I don't think that's statistically correct. If that were true, it wouldn't be recommended for depression.

[@donniebobb74]

I just stopped it because it was making me unbelievably depressed and irritable. Guess its back to Lexapro...

[@DrKevinLowe]

Hi Donnie Bobb, of course you know to keep your provider informed of any changes you are making. Thanks for sharing.

[@human4582]

Yeesh I'm taking both 😅. One for my adhd. The other for the depression.

[@donniebobb74]

@@human4582 interesting, hows it going? Im just so tired of side effects altogether....🙁

[@human4582]

@@donniebobb74 its actually working for me. I take wellbutrin in the morning and then other at night. It's been keeping me normal so far.

[@donniebobb74]

@@human4582 thats what were goin for! cheers!

[@noahbenscoter9558]

This drugs hell. I’m 19 trying to find my way in life and this is making me more confused and giving me thoughts of the past and thoughts of suicide worse than ever. I can barely function and don’t feel like myself one bit I wouldn’t recommend it I need to quit taking this shit.

[@thisgirl5933]

Please do honey!

[@harlowblackadder356]

20 years ago, I took Wellbutrin to try to quit smoking. It made me have intense dreams. These dreams were so real that I would have considered them memories except for the fact that I knew they were not real. 20 years later I tried Wellbutrin again, on recommendation of an md. I did not crush nor snort it lol. It sure did make make me hallucinate, though. Again, i knew the hallucinations were not real, so I just stopped taking it and told my doc.

[@DrKevinLowe]

Hi Harlow Blackadder, thanks for sharing that very interesting story. I’m sure other viewers will find that information useful.

[@Kyutenessss]

Yes, I had a dream of a car wreck on it that was so severe I now have a fear of wrecking in my car and brace myself. I would call it PTSD but it didn't really happen!

[@kylejohnson7777]

Name brand is real good.generic not so much

[@PaulybiGGballZ0820]

Im just getting worse and worse on it i think, went up to 300xr and its just msking me worse

[@DrKevinLowe]

Hello, all matters regarding the medication you are taking are best discussed with your prescribing doctor. It is best to discuss these matters as soon as possible to avoid adverse effects. Your doctor will be able to help you, but you have to inform them of what you are experiencing. Thank you for watching.

[@nota7660]

Just got off this and starting to feel better off than on my Dr said just stop and NOOOO taper yourself off this Rx is nothing to mess with and I DIDNT stop smoking

[@DrKevinLowe]

Hi Nota, always follow your doctor’s advice. There are other options for smoking cessation; smoking does a lot of damage to our bodies.Thanks for sharing.

[@susanmorgan4151]

Agreed! Slow with this one!!

[@scottiusnevious4838]

It gave a friend in high school a really bad siezure condition. Or i should say it made her propensity to seize higher. Like turrets but full body twitches. I never wanted to try it but it did help. Pretty cool stuff, as a pothead it is like smoking CBD.

[@DrKevinLowe]

I'm sorry to hear about your friend. Medications do not always work well for everyone. Some people derive benefit and others do not. Thanks for sharing.

[@diegofiorillo6412]

I have been on Wellbutrin for a week and I am an anxious mess

[@DrKevinLowe]

Please see your medical provider. They are best equipped to handle complications you may be having with your care. While you can learn new things in this forum, no one here can advise you about your care. Only your treating doctor can do that. Thank you for sharing. Thank you for watching.

[@AmberEmerson-n8y]

What do you think of genesight testing to determine which medication is best?

[@DrKevinLowe]

Hello, thank you for the question. In my opinion, genesight testing may be helpful in some situations. I do not think it is appropriate for selecting initial therapy, because the scientific evidence is still lacking as to the efficacy of genesense testing. A few studies have reported superior results in genesense treated patients compared with patients treated without genesense testing. Other studies were less favorable and reported no difference between the two modes of treatment. There is a danger that avoiding medications based on genesense testing may deprive patients of valuable treatment options, prolonging their symptoms and putting them at risk of complications. I imagine that genesense testing may provide some benefit in patients who have failed treatment with multiple medications. As a last resort, it may give some direction on what drug to try next. In order to place genesense testing in its proper place in patient care, we need more high quality studies on this type of treatment. Please follow your physician's recommendations on any medications you are prescribed. Thank you for watching.

[@alli138]

I have been of it for 15 years. All of sudden, i feel fatigue and sleepness. All of sudden

[@DrKevinLowe]

Hello, it is always best to discuss any side effects with your treating doctor. Thanks for watching.

[@Jedwards3rd]

Ok I’ve been on it a year now and I’m feeling the same. It’s making me extremely tired and just overall exhausted. Did you stop taking it ?

[@InstrumentalArcanum]

Is there any other antidepressant other than Wellbutrin, that doesn't cause sexual side effects? Somebody please answer this or tell me what works . Thank you

[@pieter9058]

With escitalopram I used gingko biloba, worked really well to get and maintain erections.

[@-supremebeing-]

Mirtazapine

[@Namiat825]

I’m grateful for wellbutrin. It worked wonders for me.

[@ananodeh7429]

What did I do to you?

[@DrKevinLowe]

I am happy to hear that. Thank you for sharing.

[@messyhomestead7320]

Thank you so much for this information. I can't find any info. online about what Wellbutrin did to me (paralysis, intense pain for months, lose of use of limb) but I understand from an urgent care visit and a quick medigoogle the practitioner did that day that muscle weakness is listed as a side effect. If I had known it had this level of impact on dopamine I would not have let the dr put me on it for one second, since I know what that does in my body.

[@DrKevinLowe]

Hello, I’m sorry to hear about your experience and difficulties you experienced. I hope you are feeling much better now. Thanks for watching and sharing your experiences with us.

[@mrsmjj81]

Hi. Just curious. I'm on the generic version (Extended release) and I'm noticing muscle pains (my legs, arms, upper back) and weird tingling and numbness in random places. I'm also very itchy. Is this similar to your symptoms? Any information is appreciated. I hope you're doing better.

[@messyhomestead7320]

Yes definitely and you are helping me to crystallize more about my own actually. When I finally went to urgent care for it, they looked it up online and said "sure enough, muscle weakness is right there as a major side effect that's known..." @@mrsmjj81 I made a video on my channel about my Wellbutrin experience the other day, after still not finding anything online about my kind of experience. if you'd like to join me there or do a video together, feel free. (I was on generic too, I believe extended release too...) I already had some itch issues since I have MCAS and other dysautonomia things. Would be interesting to talk and maybe bring some of this to the light for folks. Thanks for sharing!

[@supertal6074]

I have taken it and it caused my depression to escalate substantially.

[@DrKevinLowe]

Hi Tal, Unfortunately, no medication works the same way in every single person. It may be possible that other medications help you better. Thanks for watching.

[@januarybaby392]

It also caused me to experience extreme and constant depression that only subsided when I decided to quit taking it. When taking it, I could "taste" the dopamine release from the drug. The first ten days it helped me to focus and it improved my productivity at work. However, then it began to make me feel complete despair unlike any med I have ever taken. I did not use it with any other meds, and I didn't drink or use it with other drugs. I haven't used it since 2021.

[@titadaye]

@@januarybaby392 Sounds like a lie. Wellbutrin doesn’t work right away. It needs to build up to see it’s working and that would take 4-8 weeks at least.

[@bass2092]

@@titadaye not necessarily a lie. Probably placebo/nocebo effect.

[@danplantman62]

Yes ! A few yrs back o had to go to rehab a couple weeks and they put on that. Within a short period I became so depressed after taking it.I said never again.

[@9000ck]

I think you would have to take a huge amount of bupropion before getting a high. It works well as an antidepressant if taken as prescribed.

[@cxmxc]

First 4-6 months I thought I was alive. Now I’m miserable

[@DrKevinLowe]

Cam g, please see your doctor if your status has changed. There is a long list of medications that can alter your mood. I hope you feel better.

[@jackchop1576]

This is an ADHD drug for me... well, combined with Vyvanse. It keeps my dosage of Vyvanse low.

[@DrKevinLowe]

@jackchop1576 Thank you for sharing. I'm glad to hear Wellbutrin is doing well for you.

[@kobebryant-cl7ul]

great to hear a success story. Just curious, did it increase anxiety at all for you? And does it feel similar to adderall where you get effects like sweating, high pulse, and high blood pressure? Does it feel like it “speeds you up” like stimulants or no?

[@slapzk5355]

⁠​⁠​⁠​⁠@@kobebryant-cl7ulMy own experience with it. This has been my 3rd time on wellbutrin. Wellbutrin in and of itself I find doesn’t cause anxiety. I have a prescription for vyvanse and dexetrine, also for clonazepam. I don’t take anything besides just the wellbutrin. If I take vyvanse and dexetrine it makes me feel really weird and spaced out. As for the clonazepam there is no need for it because my anxiety isn’t all there because the wellbutrin. Wellbutrin definitely gives me a lot of energy. It’s almost like a natural energy. Im happy and energetic. Like I was saying adding a stimulant to wellbutrin for me personally is way to much. It is like when I tried smoking and drinking on it, it is not fun. Way happier just on wellbutrin and nothing else, not even caffeine. Caffeine gives me severe anxiety and I get really depressed on the come down. High pulse, high blood pressure, dizziness, light headedness, and my brain feeling like it was wrapped in cotton has happened to me. But that is when I was first getting on it, i was drinking, doing other recreational drugs and smoking (I know very dumb). All and all I believe wellbutrin is a miracle drug. I have tried so many SSRI’s and have had so many bad experiences. With wellbutrin I enjoy my old hobbies, I eat healthy, workout everyday, and I even enjoy interacting with others which I wasn’t all a fan of before.

[@karlaoquendo558]

I have combined type ADHD and I have tried other ADHD meds and Wellbutrin XL has been the only one that have helped me with my ADHD symptoms. The only side effect I have been experiencing is a little bit of hair loss.

[@DrKevinLowe]

I’m glad to hear that you were able to get relief with Wellbutrin. Hair loss is a rarely reported side effect. According to some investigators, it is temporary. Thanks for sharing.

[@Corleone007]

Every substance has dark side. Water give a life or take it. We have to drink water, but if you drink a lot in short time, you may die. If you have a problem you find best solution. A solution can be everything and that solution can save one's life and kill another one. What is good for you may not be good for the others. We all are a bit different, and that bit is the key here... a bit like a small second or milimiter or inch which sometimes is a small gap between life and death

[@DrKevinLowe]

Agreed. Your point is well taken. Thank you for watching.

[@nickkenmill8364]

I have been taking this drug since 2020, this last year I was also prescribed phentermine. I seriously went into psychosis and became extremely paranoid, I quit both drugs and my Anxiety has ceased and I’m just now starting to think right again.. be careful while taking any prescribed medication.

[@DrKevinLowe]

Thank you for sharing. I am glad to hear you are doing better now.

[@MarelyBearly]

My doctor gave me 300mg of wellbutrin for ADHD she wont listen to me my symptoms are getting worse and I feel nothing positive from the wellbutrin. She started me at 75Mg and doubled once and again. Now I have worst adhd and a lot of rage

[@DrKevinLowe]

I am sorry to hear that. Have you considered getting a second opinion? Discussing your symptoms with a different provider can provide a different perspective that may be helpful. Thanks for sharing.

[@pennypinson8398]

Dang I think I'll just keep smoking my one pack of cigarettes today

[@darlenecannon2873]

These meds are wonderful for people suffering from true clinical depression. However, the sub clinical depression people have a more difficult time. It does lift the symptoms except it leaves one emotionally flat. No highs or lows just a monotone.

[@DrKevinLowe]

That is interesting to know. Have other users experienced the same thing? Thank you for sharing your experiences. Thank you for watching.

[@elin_]

I have eaten bupropion for a few years now and it totally saved my libido that my ssri were killing. But.. Is there any connection between bupropion and hair loss? Because I'm losing so much hair! I feel so torn because bupropion have made me feel more human, but I don't want to lose more hair..

[@DrKevinLowe]

Hello, I am happy to hear how well bupropion worked for you. Hair loss is a recognized but rare side effect of bupropion. Some sources claim it is temporary, but I cannot vouch for that. You should discuss the hair loss with your doctor. Thanks for sharing. Thanks for watching.

[@dennisswanberg1718]

I tried it last year for a few months but I didn't notice much difference and some days I skipped it.I am feeling a little down lately even when I'm doing things I enjoy. I'm going to give it a try again with some caution. Keeping in mind that many people forget to take their Vitamins Like D, and potassium that helps with low energy levels and therefore feeling depressed. The best thing is to keep your doctor in the loop to monitor your Health situation.

[@DrKevinLowe]

Yes, you are right. It is very important to keep your doctor informed on any changes in your state of health. Only they have all the information regarding your health, so only they can make recommendations on how to deal with any problems you face. Thank you for watching.

[@CanadaKaching]

Day 1 on bupropion I feel super agitated and angry. I’m worried

[@Kaylea_Iowa]

I’ve been on this for a little over 5 years. I’m currently taking 450mg. Which is the max amount. It works for now. I will say I wished I would have gotten help with my MDD and anxiety sooner. I robbed myself of living a life that could have been much more enjoyable all because of the stigma that I associated with having to be on medication.

[@pipsuki]

i will die with Wellbutrin in my system. i cant go through that deep of a depression again. for 3 years just, nothing. it's torture. it's being stuck in hell.

[@DrKevinLowe]

Hello, it is heartening to hear Wellbutrin is working for you. Many people have reported similar results with this medication. I wish you continued success on the medication. Thanks for sharing.

[@Cvs-om3hd]

Hello, I had stop the meds because I felt it was not helping me any more and it was not a serve case. My physiologist change do to insurance change . I wanted more therapy and want to do more exercise to overcome to much thinking

[@Acemechanicalservices]

You’re on the right track, then.

[@Thebellreve]

I been on 450 for 10 years now. it isn’t like how it was the first few years. I don’t know what to do because I don’t wanna take anything else

[@DrKevinLowe]

Did you discuss this with your prescribing doctor? They have all the information needed to help make meaningful decisions. Thanks for sharing. Thanks for watching.

[@Egonzal316]

Im curently on Duloxetine 30mg q day, while my anxiety is mild compared to others', it is enough to affect my job. I hate how lethargic it makes me, so tired every day, i get 7-9 hours of good quality sleep, eat well and workout often. Literally feel exhausted.... I have no issues with sex, however, thr weight gain is awful. I want to talk to my PCP about trying Wellbutrin. Im tired of being tired.

[@DrKevinLowe]

I’m glad to see you are taking the right steps by speaking to your PCP first before making any changes. I hope the change works well for you. Thanks for sharing.

[@MXRiderFiftyTwo]

I'm on Lexapro, no weight gain at all. Zero cravings for extra food

[@nautblue4284]

If you're prone to addiction, don't take Wellbutrin. Someone should tell smokers this.

[@DrKevinLowe]

Thank you for making that point. Thanks for watching.

[@NyndDjdj]

🇩🇪❤️🇷🇺

[@michaelallen1154]

All i know is, the only time I've ever had a lift from my depression was when i took prescription amphetamine/adderall. What does that mean?

[@DrKevinLowe]

Hello, Adderall was used to treat depression in the early to mid 20th century. Depending on the type of depression, Adderall can be effective. Thanks for sharing. Thanks for watching.

[@darkwillow57]

Thanks for the tips on how to abuse Wellbutrin to get high 😅😂