Diabetes Type II Pathophysiology

[@armandohasudungan]

🎥 DON'T JUST WATCH, LEARN ACTIVELY! TRY THE QUIZ! 🤓 youmakr.ai/test-playground/questionnaire/673d3d6e859b9c170836ed2d

[@pansukikouki]

*My daughter drinks lots of water and urinates with the same rate, there are no other symptoms to show if those have anything to do with diabetes. This is a good information that I have gone through **Diabets.Care** She is 2 years 9 months, hale and healthy, have not done any blood test. But I am not certain if one can get diabetes at such a tender age. Please I will like to know more on that*

[@anasuduvitalis3917]

It’s possible

[@Roy-xf4bc]

Get her blood sugar checked.

[@herlandsson7936]

Diabetes mellitus type 2 has an average age of onset at around 45 as it is developed over time. In your daughter's case however I would find it more likely to be diabetes insipidus, even though its average onset is at around 10-20 years of age it can start at any age. It is always best to get in contact with your local healthcare institution to get your suspicions checked out :)

[@cattprez]

see a dr

[@blessing303]

sounds more like type 1 diabetes it onsets quite at an early age it's common in females especially teenagers

[@MA-or4pf]

One of my first authors to turn to whenever I start my new Biology assignment. Armando has helped me get distinctions in my coursework and I am so glad his videos exist!

[@CavanHagan]

Fantastic video, I learned a few interesting points such as why dehydration occurs, rather than just always being told that it causes dehydration! Thank you

[@davilonphotography3639]

Watching this in 2021 and I am so grateful! Insulin and glucose always kicks my ass for some reason but you have explained it BEAUTIFULLY! Thank you thank you thank you!

[@fakeornot8159]

Being diagnosed with diabetes in my early thirties was a life-altering event. It marked the beginning of a constant battle, and I tried various remedies and therapies in search of relief. None seemed to provide the results I longed for. It felt like an up

[@SionynJones]

Very interesting I've always wondered about the pathology of diabetes. Now I finally understand why a high blood sugar is bad.

[@imaneouadi67]

Great , I'm studying endocrinology this semester and I'm sure as hell gonna have a visual of how things work now

[@queenodion8165]

There is a complete cure for Diabetes type 2 with herbal medicine from Dr.uwenboherbalhome on KZbin

[@kakashihatake6936]

My journey with diabetes has been a rollercoaster ride, spanning over a decade. Over the years, I tried different diets and treatments, always in search of a solution. It seemed like the more I tried, the more I was disappointed. The feeling of being let

[@descai10]

If you're overweight, just focus on losing weight. High BMI is exponentially associated with diabetes risk. BMI of 30 has a 28x higher risk, over 35 has a 90x higher risk. Interventional trials have shown weight loss to be extremely effective in treating diabetes if successful.

[@summer-turtle]

GLUT2 in the liver is always on the membrane, it's the GLUT4 in muscles and fat which is transported. In the liver, insulin inhibits gluconeogenesis and stimulates glycogenesis.

[@marvinnelson5073]

The basic thing driving type 2 diabetes and insulin resistance is too much insulin. Using insulin in the short term to avoid glucose toxicity is ok but continued usage just leads to heart attacks, cancer, obesity and on and on. Goal must be to lower insulin, not just control blood sugar.

[@waterbuoy1262]

Tks for this conceptual visualization. Tremendous skills and talent went into making work like this. It demonstartes a simple cycle? present in some or most? diabetic. At first you oresent high blood glucose starts initiation "cascade" which splits us (diabetics) into normal or abnormal. From there very last frame we see this "separation" . Has anybody tried just going backward to normal by starting high blood glucose again? Nothing to do with 'sugar' symptoms. Clean blood proteins , turn metal s(-s) enzymatic black.

[@trishabriggs3595]

great video! helped me prepare for our short group discussion on diabetes 💯

[@sharmilabhatta3572]

Being diagnosed with diabetes at a young age was a challenging and confusing experience. It felt like a never-ending battle that persisted through my teenage years. I diligently explored various treatments and therapies, often with limited success. The fr

[@aliehramezani4792]

For the first time in my life I learned a pathophysiology lesson without getting more confused!

[@segaranpillay7154]

GREAT ARTISTIC QUALITY OF ARMANDO

[@عالماللعاب-ف4ط]

Ive been on a lifelong journey with diabetes. Throughout the years, Ive explored numerous methods and therapies in the pursuit of better health. There were moments when the weight of this condition seemed nearly unbearable, and I was ready to give up ho

[@riarkp5363]

CAC Shilajit is available in the form of Shilajit Satva. It is a potent Immunity Booster and acts as an antioxidant, possesses anti-inflammatory properties. It has a tremendous effect on Male Harmones, Anaemia, Alziehmers disease, improves brain functions, Fatigueness, various Tumours and Cysts like PCOD in females. Due to its anti-inflammatory properties it works on inflamed lymph nodes as well. It balances blood sugar, increases absorption of nutrients, helps in detoxification, helps in reducing mood swings.

[@AlohaUlises]

I missed the "Armando Hasunasdndajdagan, Biology, and Medicine videos!

[@yayamuhammadlamido8098]

Humbly appreciate your kind gesture Dr Igho , you have always been able to help with any of my health issues , i didn't know how to face the stigma of living with Diabetes, but I'm happy to say today that I'm glad to have you as my doctor because it just seems like magic I'm healed.

[@MidhunKrishnaR]

Now I know about inshulin 😁 , great accent , I love it 😍

[@buroliarahul625]

Can you make a video over the review of Diabetes in details... Much more helpful by your methods of understanding!!

[@queenodion8165]

There is herbal cure for Diabetes with effective medicine from Dr.uwenboherbalhome on KZbin

[@physioweng]

I have a question here. If extra insulin produced by the pancreas doesn't work anymore due to insulin resistance of the organ tissues and skeletal muscles, then why would insulin injection (which pretty much has the same effect) help in reducing their blood sugar level?

[@dishalini6134]

that’s exactly my question too

[@johnhogue9402]

It's all about concentrations and likelihood. With a higher concentration of insulin in the blood, the likelihood that insulin will bind to an insulin receptor increases. The worse the insulin resistance, the more insulin is required to do the same job. That having been said, there is good evidence that tight control of blood sugar (via insulin injections) in diabetes doesn't actually help the patient.

[@dr.scifreak]

In type II, insulin shots are only needed when beta cells exhaust themselves due to overproduction of insulin to compensate insulin resistance.

[@AlohaUlises]

Dude, it depends on the actual stage of the Diabetes you are in, and wether it is insulin resistant or dependent!

[@sosysosy555]

what I know in addition to insulin injection, they give with it insulin sensitizers so it can work, I hope that helped

[@victor3431]

Your explanations are the best

[@westfield90]

Can you do a video on gout and why it’s mainly in the big toe and what causes it and why it’s so painful

[@Nisha-kl8rl]

Thank you for highlighting the benefits of Ayurveda in diabetes management. It's refreshing to see a holistic approach being discussed, and Planet Ayurveda seems like a trustworthy source for natural solutions.

[@ramiali3677]

Thank you very much .plz do more vidoes about neurosurgery

[@m_m786]

Great 👍🩺♥️

[@dileksoysal2655]

I like the way of your teaching.. thank you.

[@perderepeso8272]

Why do some overweight people have more of a predisposition to developing type 2 diabetes than others? *For more information My Profile In About* Or Bio, How Diabetes Is Cured Totally

[@marif5972]

I am having a hard time understanding the part where there is insulin resistance. I understand since there is too much insulin because the receptors are not working but how is too much insulin causing a higher concentration of glucose?

[@wildfire7268]

What does insulin do to fatty acids? Insulin inhibits breakdown of fat in adipose tissue by inhibiting the intracellular lipase that hydrolyzes triglycerides to release fatty acids. Insulin facilitates entry of glucose into adipocytes, and within those cells, glucose can be used to synthesize glycerol. www.vivo.colostate.edu › pancreas Physiologic Effects of Insulin -

[@muhammadyahya110]

Thanks mr. Armando ..❤ 04:15 Actually it is Glycosurea ...

[@muhammadyahya110]

GLYCOSURIA😊.

[@reesebrits9381]

Love your videos! Thank you for your awesome explanations.

[@jyotibisht2654]

Earthyboon sugarvita ras can help diabetic patients by stimulating the production of insulin from the pancreas, thereby keeping the blood sugar level low. i have personally use this from last 02 months, and i have controlled my sugar level...Please try this.

[@wildfire7268]

Can fatty acids make acetyl CoA? Fatty acids are broken down to acetyl-CoA by means of beta oxidation inside the mitochondria, whereas fatty acids are synthesized from acetyl-CoA outside the mitochondria, in the cytosol. ... Instead the acetyl-CoA produced by the beta-oxidation of fatty acids condenses with oxaloacetate, to enter the citric acid cycle.

[@Janix18]

Amazing video!! So easy to understand and retain

[@wer1339]

Can somebody tell me please, how do insulin receptors become not sufficient or why do they stop working properly?

[@bhatsafoora6986]

Thanks ❤

[@mohsinfareed1797]

Great man with great videos. Thanks.

[@fangyap9266]

very well explained! thank you:)

[@shubhankarghosh-2046]

Sir, has liver GLUT 2 (insulin independent) for glucose uptake unlike muscle and adipose tissue (GLUT 4) ? If it is, then glucose uptake by liver will be unchanged in T2DM.

[@Falcon_bites]

A 40 year old female presented with 2 months history of polyuria,weakness,fatigability and pruritus vulvae. During her last pregnancy 2 years ago she was found to have raised blood sugar for which she was put on insulin which was discontinued after delivery as followup blood glucose levels remained normal.on examination her BMI is 36,pulse 80/min,BP 150/96mmhg rest of examination is normal what is the diagnosis for this condition .? Gestational diabetes or type 2 diabetes

[@SharingWithU]

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[@sethfisher5413]

I have found these natural blood sugar/diabetic support medicine management capsules to be a great help. They really work wonders.

[@sethfisher5413]

ceracare-health

[@carolineroy9034]

@Armando Can I get this PDF for this video

[@abbailiyasu3316]

Your generosity towards curing me from diabetes is incomparable, I was tested negative under 18 days, you are a blessing to humanity Dr Obaz.

[@RoyalNatangwe]

How does insulin cause reabsortion of Na and Ca

[@lizethflorescotrina9228]

I love your channel! Excellent work

[@yvanmontes9222]

Lovely Video clip! Sorry for the intrusion, I would appreciate your initial thoughts. Have you thought about - Loowarn Inconceivable Desire (google it)? It is a great one of a kind product for getting rid of diabetes type II minus the hard work. Ive heard some super things about it and my buddy got astronomical results with it.

[@adilahaidari674]

but why do we treat type 2 diabetes with insulin when the problem is not with insulin production but the sensitivity of the insulin receptors, are those receptors going to react to the insulin we are giving? i was waiting for that explaination

[@amedmubi1559]

Vielen Dank, Super und einfach erklärt

[@HASAN_NASER.Dr20]

Amazing video. thank you very much

[@prakaimartintarasuwan105]

Is egg good for diabetes?

[@johnhogue9402]

Insulin has more than one action

[@fiskanurahmilubis5773]

My first attempt to control my blood sugar was to eat a more low-carb diet, which helped a lot. If I stuck to a VERY restrictive diet I could keep my blood sugar where it needed to be. But if I had even so much one ham sandwich one white bread or one fast-food meal, my sugars would spike and stay elevated for quite awhile. I fundamentally distrust pharmaceuticals, believing that they often cure one problem only to cause one or more other problems. And I have tried herbal supplements, but the ones I tried did not work. With the Halki protocol, I still cannot eat anything I want, but I can eat a reasonable diet (some paste and white bread and the occasional fast-food meal) without my blood sugars spiking. And when I do eat some sugary treat, my blood sugar still spikes, but not like it used to. for mmore information visit here tinyurl.com/halkyremedy >

[@johann23]

GLUT2 receptors in the liver aren't insulin sensitive, bro.

[@Necromager]

Great video! just one thing: don't Bcells hypertrophy instead of atrophy in this case? if they are producing more and more it should make sense that they get bigger, not smaller. Please, help!

[@bartwilson2513]

João Ferreira with type II diabetes there can be a >60% reduction in mass in pancreatic beta cells. They are highly metabolically active and quite complex. There is a more full discussion of beta cell dysfunction and insulin resistance here: www.ncbi.nlm.nih.gov/pmc/articles/PMC3608918/#!po=3.96825

[@thefenerbahcesk4156]

So how do insulin injections treat it then? Isn't the body resistant?

[@shayona1460]

same question

[@wassimabdou7649]

any answers since ?

[@tremen2140]

Not sure this is useful to you now, but for future reference: Initial treatment of T2DM is weight loss/lifestyle changes to reverse insulin resistance (since resistance depends on gene expression which can be reversed), as well as insulin-sensitising and releasing agents such as metformin or sulphonylureas. In late stage diabetes type II, the pancreatic cells become so hypertrophied and amyloid plaques proliferate so far, that beta cells stop producing insulin, and then insulin injections are necessary, since the issue stops being hyperinsulinaemia but rather hypoinsulinaemia like in T1DM

[@eloisecobby-smith5058]

this was great, thanks so much!!

[@lingampallysrikanth5298]

why insulin receptors are not working properly ?

[@blonyynka]

Do I understand correctly that first insulin secretion increases due to ineffective clearance of sugar molecules out of blood and later on decreases significantly due to atrophy of beta cells? I am a bit confused and looking for an answer because I can recall from pathology clinics that we were jokingly “locked” in the auditorium by out lecturer (with a good sense of humour) until someone says correctly whether insulin goes up or down during initial stages of insulin resistance development 🤣 I replied that it goes up and we were released 🤣 many years later I am keen to understand why this happens

[@af2830]

Excellent video, thanks a lot.😄

[@madil2259]

Good video. The sound was too low. Please fix that. Thank you.

[@jamesmkandawire8976]

Kindly asking for diabetes type 1 Armando Hasundungan 🤲🤲🤲.

[@borashnikov]

hi, great video, very informative. i feel like its very important to consider the physiological limitations to diabetes type 2. i know there is endothelial dysfunction and supression of nitric oxide release thats responsible for vascular fibrosis and micro damage, is there any other limitations caused by type 2 diabetes? im sitting my final exams for phsyiology, so any help is appreciated.

[@camilledeeny4591]

SO helpful, thank you! :)

[@christinemadalenecrystal1267]

Can glucose levels be normal in diabetes type 2? *For more information My Profile In About* Or Bio, How Diabetes Is Cured Totally

[@wayanadtoday]

What an explanation

[@wildfire7268]

What is the breakdown of fatty acids to acetyl CoA called? lipolysis This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl CoA, which is used by the Krebs cycle. courses.lumenlearning.com › chapter

[@sumitgupta4414]

great sir...

[@maryg6292]

We have been controlling my husband's T2D with diet for 30 years with very low carb, high olive oil. Now I learn that whey protein powder, while reducing blood glucose, does it by SPIKING INSULIN for hours - which is bad. I got into a couple of Australian sites and found that it has been known since at least 1997 that blood glucose means very little. It is the Insulin Demand Index that is relevant. A low carb item such as whey can be horrible because the insulin spike dramatically, while you sit with your blood glucose meter none the wiser. Can you shed any light on this, which flies in the face of the medical advice we have been given? Thanks.

[@opritchard8611]

Mary G sadly its not as simple as that, plus most of the studys looking at Insulin Demand Index state as a conclusion that its not an appropriate indicator for diabetic control. Furthermore you have to look at study size and patient experience. Its true many proteins cause insulin spike because of its involvement but genetic predisposition plays a huge role in the impact of insulin resistance and level of insulin release, rather than mere indexes, this is because of the cascade of chemical reactions involved in diabetes.

[@satrah101]

".....by SPIKING INSULIN for hours - which is bad. I got into a couple of Australian sites and found that it has been known since at least 1997. Do you still have the links. Would like to read them. Thanks in advance.

[@manjeet1278]

I have heard that diabetic persons start secreating uncontrolled insulin?

[@primrose6294]

Thanks teacher

[@nafisayunusa6943]

really appreciate your good Work Dr Oiah on KZbin , Thanks for Curing my diabetes sickness . No more Pains and sleepless night . I bless they day I meet you on KZbin , you have been a blessing to me . Thanks Dr Oiah🤗

[@mercyfred4431]

Thank you Dr Osas for curing me from diabetes am forever grateful sir.

[@shwetanagare1332]

Who is dr osas and where is he from and currently

[@shivanimitta5660]

Helpful thankyou

[@gabrielbernard9905]

Thank you :)

[@mariocesarbenitez5552]

Thanks ver much

[@shahadhamed638]

thank you

[@beeshoney8085]

What's the point of injecting insulin if the cells are resistant and it was the cause pancreatic b cells atrophied

[@Trik2Amv]

it could have more details than this, but it still good though.

[@drkevorkian2396]

The pancreas looks like the Red Wings logo.......any connection?

[@anphyantony865]

Learn how to actually Reverse type 2 Diabetes here, watch this full video diabetesfreedom.org/?hop=antony2468

[@marshalazizmaihendra3414]

@@anphyantony865 The method you shared online helped me to stabilize my blood sugar and lower it to acceptable levels. And that’s not all because I also lost 36 pounds and I’m the same size as I was at 29. I was skeptical about your solution at first but I'm delighted I gave it a try. I’m totally free of the daily pains I had with my diabetes such as horrible side effects from medication and eating tasteless meals. for more info click here tinyurl.com/y3r77wry >

[@barnabasmuplang-nk4fp]

Thank you Dr Igudia for being the most trusted doctor among all, your professionalism was on a high standard, thank you for coming to help me out with my Type 2 diabetic

[@hwanski]

very useful presentation ! But one thing, at 3:03 you say that the insulin receptors don't work properly anymore and you paint the insulin receptor at the liver, but aren't the liver as well as the pancreas insulin independent organs ? I think I am confused haha

[@notlisztening9821]

wtf is Inshulin?

[@ratneshsharma4344]

Why type 2 dibetes patient need insulin therapy they have also high level of insulin in blood

[@onyebuchiaugustine6275]

Dr osoria is the greatest, he has been very attentive to my Heath issues. I have bad complicated heath problems and he has addressed them all. he is very kind and patient. I'm very great full for saving my life Dr osoria I'll share my testimony to the world #drosoria

[@bernarddeekor7693]

I really appreciate your good work Dr Ogoh towards helping me get rid of my Type 2 diabetes with your natural cure.

[@fyt_harsha598]

Super

[@SomtoNwangwu]

Pls i did not understand polydipsia

[@adamualiyukukawa3748]

Words failed me on how to appreciate you for sending your Herbs to me after I place my or order which cured my type 2 Diabetes Dr Igudia

[@kohinoorrahman5707]

I want to learn about kidneys

[@waterbuoy1262]

those are the organs (2) of them , internal filters water from blood. Learn here-> 'Ruoy' tube||s on dia*lie sis.ter

[@abbasmukhtar6703]

This has been a challenging time, and I appreciate you so much Dr Igudia, you have created a life that I thought was lost, thank you so much for curing my diabetes.

[@muhammadshafiq50]

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[@ogebuleadetola9926]

Great experience doc, you are a God'sent dr odija on KZbin, keep up the good work, I am completely free from HIV virus ......

[@deboraheyitayo40]

Thank you for being the dedicated, thoughtful, and compassionate doctor that you are, you are more honest than I imagined, thank you so much Dr Igudia KZbin channel for curing my Type 2 diabetes, you are amazing

[@shehunafiu6624]

I appreciate meeting you Dr Adesuwa you bring out a huge smile on my face because I never thought I will be cured from diabetes all thanks to Dr Adesuwa if not for him i never could have known what will happen.

[@annawestby510]

I liked the video. I have been trying to find for a video like yours that informs everything in this KZbin vid! The part at 1:03 is my favorite. Your breakdown is like the videos of Dr Ethan! Doctor's demonstrations are for sure useful and I actually learned a lot for my studies. He is an educational med student. Go watch his channel out and give the med student a subscribe over here! ➡️ #DrEthanEducational

[@effestop]

Can someone explain why liver is always depicted in two parts, with that little triangle on the right? Thx in advance.

[@satrah101]

Hello Tiziano the liver is divided into two main lobes the right and the left. Google search liver + lobes. Hope this helps .

[@effestop]

wayne hart thank you!

[@sarahschlotfeldt8698]

Meeting Dr IGUDIA KZbin channel was the beginning of a new life for me after using his herbs medication in curing my Diabetes disease.

[@mariagorettisousa8559]

Thank you Dr Aba for curing me from diabetes am forever grateful sir

[@cesarcdx]

Diabetes Type III

[@ajuobasi548]

God bless now and always Dr Igudia. And I really wanted to say a very big thanks for helping me cure my Type 2 Diabetes I thought it was the end until I meant you keep saving lives doctor.

[@shoey2257]

I wish i could draw this lol