Lipid Lowering Agents (Cholesterol Drugs)

[@madinaradjabova1668]

HM*G (good for) *CO A (coronary artery)

[@rachael4775]

this is literally the most brilliant little trick ever my jaw is on the floor hahha

[@rosatwinkleblossom]

Genius. Will never forget this

[@erikramos1972]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@TheRyanChang]

for PCSK9 inhibitors Pesky (PCSK-9) muhammad ali (ALIrocumab) Evolved (EVOlocumab) boxing. This also helps us remember the side effects because you have NEURO effects and soreness (mylagias) from boxing

[@nehadharap700]

ahhh,THANKS DUDE!

[@rosatwinkleblossom]

Thank you!

[@omenazuvictor2619]

Hi Dirty , you have absolutely saved my life. I have been dealing with this topic( + anti diabetics , which i also watched ) for the longest time but right now , i feel confident to answer any question in these sections . I have step 1 in 2 weeks and i promise to give back to this community when i start earning . You are the absolute best . Thank you from the bottom of my heart

[@justaryana]

Dirty, you did it again. you really did do a better job teaching this than ANYONE else. and in the nick of time for my exam!

[@tesnimhamdan5813]

My exam is in 2 months and your videos are so essential during this period. You just simplify everything, especially pharma which is so hard to memorize. I watched your video on HIV drugs and I answered the UW questions like it was nothing. Now I guess the lipid lowering agents will be a piece of cake as well. Thank you so much!

[@hehateme1187]

To remember the ↓ LDL exceptions, Fibrates and Niacin, I added this little mnemonic: fibra↓Tes (↓ TG) and "Nancy is extra Hot!" (Niacin - ↑ HDL - flushing) For remembering the majority decrease LDL, I remember "All the fatties drop it LOW LOW" (Lipidemia drugs ↓ LDL lol)

[@Marsool-r7p]

Dude, you're like a magical teacher that I go to when ever I stuck in a subject.

[@fireman00742]

Dirty medicine is by far my favorite learning tool. I have not purchased a text book in my FNP program yet. Thank you !!!

[@georgiabessie]

How’s school going? I’m in year two FNP. I love these videos.

[@doom_inik]

exam in 10 days, coming in clutch with this topic cause first aid had a lot going on with those visuals (same with sketchypharm), but you made this v easy to follow👍

[@yummy1857]

It’s a measure of how interesting your videos are when I’m watching them on my break after exams lol

[@hivalee6992]

might be your best video

[@yashpawate1306]

Perfect time for my pharm test tomorrow. Thank you so much!

[@umairjaved4755]

@Dirty med my exam is next month. Kindly upload one video on Adrenergic system. P.S: Thank u so much for every video. May God bless u for that

[@tjm1434]

Just what I needed. High-yield.

[@uswahsiddiqi238]

Thank you so much! Will definitely support via membership once I start earning! THANK YOU

[@shanazannaleeguptar8075]

I used your channel and I passed pharm 1, using rn to see if i can pass pharm 2, great work sir

[@sanjananayak4348]

Thank you so much! You have no idea how much anxiety this topic gave me before this video.

[@veenaveena797]

Your teaching method helps to register and retain facts...

[@palomiichimplin2855]

Thank you so much for your support 🇪🇸👏🏽👏🏽👏🏽

[@VivaLaVittoria]

Great video. I'm currently studying to be an FNP and your content gives such great overviews of different content areas.

[@25lizfair]

Thank you for the video! one thing to clarify...don't fibrates also increase HDL? via PPAR-a? the take-home points at the end only point out that niacin increases HDL, and that fibrates just reduce trigs

[@nurula1783]

running out of things to comment in your videos but they really are helpful

[@jaclyngordon8031]

Thanks!

[@GabrielSantAnaCarrijo]

In portuguese they translated "Bile acid resins" to "Bile acid kidnappers" which is just 1000% better

[@ceccato91]

It can be named as “bile acids sequestrant” in Europe!

[@sarasims2207]

really was the best explanation i ever heard thus far ! :)

[@professorcensored3647]

9:47 "but who cares?" cracked me up. Thank you

[@anacarolinacostapontes5506]

Hi!!! Greetings from Brazil! I love your videos! They are incredibly objective and accurate! I just wanted to say thank you so so much and please keep it up! Also, just a small correction: estatins are actually competitive inhibitors and not alosteric inhibitors: they bind to the active site of the enzime HMG-CoA-redutase, taking the place of the substrate HMG-CoA, as opposed to binding to the allosteric site and inducing a conformational chance of the enzime that makes the binding of the substrate to the active site impossible.

[@ekrajghai6525]

Thank you so much dirty medicine! Watching your videos makes me forget all the other resources Im using.

[@garrettmorgan9926]

Thanks Dirty! Mnemonics: NPCs are Eze. LFTs are Eze. EzetimIBe Intestinal Brush border.

[@moob2020]

Can you please upload a video about opthalmology (especially fundoscopic images )

[@sdnyanzi]

No

[@obeymadzingo6152]

thanks for the table at the end!

[@zorrento14]

My exam is in June and I'm clenching my pearls rn

[@Kittendoc]

Same

[@HuevoBendito]

Mine's in July. We got this!

[@omnasharma955]

Could you please make a video on diuretics? Thank you

[@lauraliranzo]

WOOOOOW thank you so much! much love from DR

[@maryemmallick2752]

you promised making it easier for us and you kept your promise. KUDOS😍😇

[@beatriz.e.m7545]

hey just a question because you had said the Fibrates second pathway via PPAR a increases the HDL: which would mean that HDL would be increased for both Niacin and Fibrates how come you only put a decreased quantity of triglyceride in fibrates?

[@josephakalonu1052]

HDL would be increased by Niacin only.

[@JaehoonWrestling]

Your lecture is so easy to understand and ty for your contribution!!!

[@nola-baissa2433]

Great video as always. What about Thiazolidinediones?

[@usmanwisa3386]

Excellent explanations

[@ksharma103]

Much needed!!!!

[@ann26614]

Thank youuuu so much!!! THIS literally saved me!

[@vietle1313]

this man the goat

[@mariamshabbir198]

Amazing Lecture!

[@mohannedjamal9471]

amazing, just wanted to mention that resins can increase TGs by increasing VLDL

[@johanlalnunmawia3818]

Wow ! Really 😲

[@zuhramuskan5563]

HOW? WILL YOU MIND TO EXPLAIN IT

[@DrB56]

what an awesome explanation!!

[@shen3998]

Amazing work dude 👍keep going

[@moji1466]

Not the nerdy academic career 😂 ! Great video

[@AN-zg3sr]

Cholestrol is not bad it's the oxidised lipids which are nd in presence of glycation..the combination results in CVD

[@محمدامجد-ظ7ر]

Thank you very much bro. 🥰

[@nigelwang2447]

Primates bring stones to the PPARt-ay 😂

[@duocphamtruongtho4462]

Its so helpful, thanks so much!

[@foodiesworldUSA]

Hi is Fibrates for inc HDL and niacin inc HDL is in error?

[@RidaZaynUnscripted]

The best explanation, Thank you 👍

[@Buttercup1242]

Thankyou God sent angel

[@Army_Dentist]

Dirty you are super clean with concepts🎉😅👏🏻

[@tejashwiparuchuri7639]

you are the best!

[@jhalajayraj130]

Life saver video

[@globularfish2074]

You can use "NPCs wearing TIMs are at the IBorder" for the ezetimibe if you need a mnemonic

[@deeeeep806]

super helpful video, thank you!!

[@Nisarashna]

how can i will find this pdf??

[@beenishj]

You're a legend, dirty 🙏🏻💯

[@drmoctarali7385]

From somalia you are one in billion

[@uzmabaig465]

Thank u so much for this video

[@MedManiac1]

thank you for saving my life!! 😭😭❤️❤️

[@Nishamukherjee1995]

Thanks a lot sir

[@alih6953]

Thanks

[@nasimmalakoti7031]

You're amazing

[@xaaboopinkly]

Thanks sir!

[@drdianellyspintobenamaraap5935]

love this channel

[@shanemckenzie8681]

Not being mean bro, but your voice soothes me to 😴 stay awesome

[@adaezenwankwo6754]

This guy is good

[@dream_catcher430]

Thank you very much 🙏

[@raelleahmoore]

the GOAT.

[@priyam1550]

Thank you!

[@AhsanKhan-wo2ql]

Its the mnemonic juicelord himself

[@yaalia.s9033]

cant thank u enough

[@TheRebellefleur27]

thank you

[@Lights0ut]

Find the odd one out 1. Atorvastatin 2. Simvastatin 3. Nystatin 4. Rosuvastatin

[@TusharMathapati.]

Nystatin because it is antifungal and others are not

[@TheGhadaelarbash]

Note: PPAR-Gamma was mentioned in the insulin drugs "Bring Glitta to the party"...Glita was the drugs of TZDS and Party MoA

[@elizabethdean1209]

Thank you for your incredible generosity in the work you do! You are making the world a better place in a big way! Have you ever considered a life time membership option? I would love to support your work and my ongoing education for life. Dr. Been has the option of one time payment for unlimited access and I love the idea! ✌️ Liz Dean

[@graywolf2600]

Do you have a source on the dementia adverse effect?

[@DirtyMedicine]

Bottom line seems to be that FDA was concerned enough about cognitive changes. Be it statistically significant or not, it is worth knowing about imo: link.springer.com/article/10.1007/s40264-015-0296-6 www.ahajournals.org/doi/epub/10.1161/CIRCRESAHA.118.313238

[@meethamallawati850]

Please come and teach at our college

[@williamkudiewu1032]

Dirty is crazy man love this guy

[@lauraliranzo]

You are theeeeee besssttt!

[@bandanaghimire6427]

Good

[@Azhrxy]

So thank y dr.

[@grace_cee9335]

Thnk u so so much

[@thesweetpotatogirl]

Thnk you🌟🌟🌟

[@ahmadcheema7198]

Thank you ^_^

[@ЗверозубыйЯщер]

Love from Russia 🎉

[@jamesgordon8867]

Where is Chromium?

[@padmajahawaldar4319]

Thank you dirty ❤

[@omerhaseebkhan]

salute to u

[@UsmleAspirantPediatrician]

What I think is that although you eat fibers so that you don’t get POOP STONES, FIBRATES make you stones 🧐

[@arizonablossom8635]

Thanks a lot dirty medicine🙏

[@darkmoon3646]

DIRTY U FREAKING LEGEND

[@sleepytraveler369]

No mention of gallstones with bile acid resins? Wtf dirty

[@deadricchampion6856]

Based Dirtymedicine

[@puneetgill4994]

💯