Purine Salvage Pathway

[@alih6953]

This man is the Godfather of KZbin Medicine. Press Like to give the Don some respect

[@salmanmughal1816]

AstaghfirAllah brotha

[@alih6953]

@@salmanmughal1816Lol I know what that means xd but it is not blaspheme to say Dirty Medicine is awesome

[@misterolives98]

something extraneous to note: azathioprine and 6-mercaptopurine (which was mentioned in the purine synthesis video i believe) is metabolized and made inactive by xanthine oxidase. in a question, if a patient is taking those medications and is also given allopurinol to perhaps help their gout, then you run of risk of azathioprine/6MP toxicity/buildup

[@CoctailBae69]

thanks mate

[@BoonkedGang]

Which manifests as a mild rash

[@dge.]

Dirty come thruuuu!!! You're the light at the end of the dark, dark tunnel called obscure med school topics. Thank you for everything that you do, i love you!!!! ♡

[@drabdihakimmohammedaare7402]

Could you please do regulation of gene expression ? Thank you for all your videos!!!

[@Geoblek1]

If are wondering how AMP is linked to this reaction , IMP can be converted to AMP and GMP. AMP is converted to its nucleoside Adenosine, and adenosine is then converted to Inosine by Adenosine deaminase hence salvaging AMP. Adenosine deaminase deficiency is the major cause of autosomal recessive severe combined immunodeficiency

[@BDBron824]

Wow I literally searched for this video an hour before you posted it... you the goat🙏

[@lailametwaly2040]

Very beautiful explanation ❤thank you and if have time and willingness please cover all biochemistry topics for step 1. 💐💐

[@sambadie9407]

I have so much respect for this man I swear. Thanks Dirty if I pass step 1 next week I'll be thinking about you brother

[@bandar14201]

Did you pass? Did this channel help with bio?

[@sambadie9407]

@@bandar14201 yea bro! dirty, pathoma and boards and beyond. helped a lot. the questions were very similar to the new free 120. long long long

[@lichh64]

Is your biochemistry playlist tailored to a specific order or I should go in the order I see appropriate?

[@DirtyMedicine]

Not really. Any order should be fine

[@debigdogk9563]

Awesome teaching, Alway the BEST. Thank you. God bless you for teaching and sharing ❤❤❤❤❤

[@ΝίκοςΤζ-ρ3γ]

Great video, although I think that especially ADA deficiency-SCID and to a lesser extent cladribine-pentostatin (hairy cell leukemia) are also quite high yield!

[@Johnny-Michael]

Keep up the videos! Very Helpful!!

[@yudeeudochukwu4193]

I'm in dedicated for step 1. You save me at least once a day!

[@nishikasingh2024]

After giving allupurinol or Febuxostat, What would happen to the excess free bases in our body?

[@tmujir955]

I wish you would have talked about SCID and adenosine deaminase as well

[@HelenAsegid]

Has much help thanks 😘

[@sawapan_k7]

You are just doing amazing job!!

[@hiiii4854]

Thank you so much for the third time ❤

[@hiiii4854]

❤

[@mosessesay7829]

God bless you

[@TataCruz19]

Thanks so much

[@nusratanwar6199]

perfect bro!!

[@nesrinaa4844]

thank you

[@osamaal-faqeh3462]

thanks

[@cristobalalmendares2645]

Thanks Dirty😊

[@kilkure]

I FUCKING LOVE YOU!