DNA polymerase 1

[@Barfijalebi]

Sir kisi bi u tuber teacher ki.itni sari or itni detail me video nhi Hoti.aapke channel pr hr ek topic detail me mile Jata h.thank u sir . AAP video baane k liye bhut hard work krte ho.and kitne time se bna rhe ho video..thank u Bina money liye itna detail or aache se teach krne k liye..🙏🙏👏👏👏

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

[@snehalshinde635]

In this lockdown, I lost my interest in study but your videos bring it back. The way you explain is too good. Thank you so much Sir🤗🙏

[@shomusbiologyofficial]

You're welcome

[@hafsaazizfatima1487]

Hey sir ! I am from Pakistan ......and I am the big fan of you .......so so easy way of presenting your topic .......I have seen your most vedios ......Allah pak ap KO is ka ajr dy

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures. Please subscribe and share

[@peachlife5118]

You are AMAZING!!! Your videos are my secret weapon in biology hehe

[@deefaaabulous9081]

Omg thank u so much, I was so confused and u explained this very well.

[@gracel2mart]

These videos are 4 years old but go into a level of detail other videos don't. Very helpful for reviewing for my biology final!

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@bhanuprakash2232]

Aree bahi aagg lga diye tum to kya samjhye ho bro ....thanxxxxxx

[@gunjanpatidar8403]

sir, I don't have any word for your explanation and your efforts thankyou sir

[@shomusbiologyofficial]

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[@glamourofrealworldbysecret2599]

Shomu Sir you are always my inspiration

[@shomusbiologyofficial]

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[@nargishaider7229]

Today I first time subscribe your channel....great one sir😊😊😊

[@shomusbiologyofficial]

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[@fahaddar3424]

Thanks a Lot sir .ur lessons r reaLy understandable and very easy to remember. I really need a teacher like you in the college sir. May Allah swt bless you.

[@mm9492]

Thank you for your clear and helpful explanation. Great Job.

[@ashajha8558]

Mohamed Moalin no NJ MB

[@SkyviewKEducation]

Clear concept each and every point right now.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@shyworthacademy4151]

So nice...I am going to make Hindi version of it.😃

[@shomusbiologyofficial]

Glad it helped

[@shyworthacademy4151]

Thanks for your appreciation sir...you replied it's a lot for me😃

[@princykatiyar3745]

Waoo you did great job... thanks for doing soo....

[@princykatiyar3745]

I subscribed your channel...😄

[@shyamtripathi5526]

Hmm it's more than awesome...I also subscribed...you are doing great

[@khanatik3787]

Thanks for such a excellent explanation

[@shomusbiologyofficial]

You're welcome

[@anishagulgule04]

Tysm sir!!!It really really help me a lottt

[@shomusbiologyofficial]

You're welcome

[@LaMissBoutique2000]

Your explication was very clear ! I finally understood :)

[@shomusbiologyofficial]

Glad you liked my lectures

[@ryanzumwalt4505]

Great video! Helped me get an A in AP IB Running start Bio 7!

[@ayeshanoor9464]

finally mere confusion khtm huwe JAZAK ALLAH

[@suganyasivakumar6972]

please elaborate 5' to 3' exonuclease activity of DNA polymerase with reference to nick translation and strand displacement activity

[@imsunny3416]

U r like our class topper explaining a topic..btw that topper is me

[@imtiazalimohammed4363]

Thank you very much Shomu sir.

[@shomusbiologyofficial]

You're welcome

[@Manisha-mf2qe]

Brilliant 👍👍

[@shomusbiologyofficial]

Thank you

[@prakashpawar1503]

Amazing! Simple superb!

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@prakashpawar1503]

@@shomusbiologyofficial You are a genius brother

[@codydaneluik8364]

Excellent video, and explanation!

[@adorebeats3347]

Thankyou!!! Soo much sir🙂🙂

[@shomusbiologyofficial]

You're welcome

[@sakshishukla1523]

What is exactly that point sir where you mentioned about a free 3- OH' ?? Not exactly getting abt it. Could u plz help me with it ??

[@FatimaKhazaal534]

Thank you

[@shomusbiologyofficial]

You're welcome

[@leonardbinene8655]

Good job man!!

[@subhitakumari4179]

Thanku for your good explanation

[@aboutstudies123]

It is very helpful Sir. Thank you

[@AGMP9]

Thank u sooooooooooo much ❤️ sir🙏😊

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@nonenone5741]

اوي شكد احب شرحك🥰😊

[@thechosen123isme]

So helpful! Thanks.

[@assusunkara786]

Plz sir give a lecture for genome organization

[@xlemmyxlemmy4493]

Question!!!! If the DNA polymerase 1 in a given cell were non-functional,how would that affect the synthesis of a leading strand?

[@MimmiEkman-h2i]

You are a star!

[@minchan9522]

tbt time when ur voice not so husky and deep and could be heard clearly cuz i can't seem picture the function of exonuclease removing primers from which end 3/ but how and why doesn't oakazaki fragments join together

[@lavanyaduvvuri2611]

At the end of the DNA replication Rna primers are replaced by Dna material by DNA polymerase-1. And we know that DNA and RNA simply Differ in only 2'OH grp. My question is instead of simply Removing that 2' OH grp why cell completely replaces that RNA primers with DNA material?? And at 11.2 min u mentioned that Pol-1 performs nick translation. but it is performed by LIGASE???

[@leenalalson7777]

Sir, which polymerase polymerise okazaki fragments? I or III

[@shyworthacademy4151]

Pol 3

[@sameerpatel9521]

fab sir

[@shomusbiologyofficial]

Thabk you

[@ayeshanadeem2416]

sir i have a question ... if dna polymerase can onlu polymerize off an available 3' end, then from where does dna polymerase 1 get 3' end for replacing rna primer?

[@shomusbiologyofficial]

3' end was free there

[@jaywm2453]

thx🙏

[@shomusbiologyofficial]

You're welcome

[@mongamonga1477]

very helpful

[@vnerocha]

thank you, friend. It really helped. ^^

[@farahqaryouti2018]

thank you thank you thaaank youuu 🙈❤

[@bhaskarthakur1068]

Nice sir

[@meenakshikumari7821]

Sir plz make a video on probes

[@shomusbiologyofficial]

Okay

[@ImAllArtsy]

thank you!!!!!

[@shomusbiologyofficial]

You're welcome

[@emilioconde8782]

Thank you! one question though I read that ligase was in charge of removing RNA primer...

[@shomusbiologyofficial]

+emilio Conde no. Ligand only seals nick.

[@emilioconde8782]

Shomu's Biology Oh now that I re-read I realized I missed some steps. So RNAse H detects the RNA primase, Poly 1 replaces RNA with DNA complementary to the strand and then Ligase fills the nicks!! thank you for commenting so quickly and showing me what I don't know.

[@ZakAli9904]

Kkkkk

[@kashyapbrahmandam6991]

thanks

[@maimoonaafridi8771]

If exonuclease has to perform cleavage and cleave wrong nucleotides which is same activity peformed by POL 3 that does proof reading, how are they different?

[@shyworthacademy4151]

DNA pol 1 and 3 both have same 3'->5' exonuclease activity, which is also called proof reading activity

[@alyaaalmery7939]

What's meant by nick translation that you said in the video?

[@suganyasivakumar6972]

please address this as fast as you can , as imagining this activity is difficult for me .... please

[@noopursingh2730]

thank u sir for this gud explanation. sir i wanna join online test series for csir net jrf

[@zarrahosainy1508]

thanks but i don't know what u said about the couses. the subtitle cant read it too what would the couses be plz its after u said mutation?

[@ashajha8558]

Umullbanin Hosainy

[@sreenivasravula6173]

Biochemistry?

[@lalithasri3617]

please also make a video about the list of central universities exams we have for M.sc entrance in life sciences stream

[@sahilkhilo8865]

Sir translation process

[@shomusbiologyofficial]

All explained

[@sangtruongtan5585]

Can you help me this question ? Why does DNA polymerase I not form phosphodiester bonds between new and old circuits ?

[@sho7393]

教授より分かりやすい

[@bismaaslam854]

Mjy English nae ati😭😭😭😭

[@klumayank9161]

please eplain in hindi

[@shomusbiologyofficial]

Sure

[@milankushwaha760]

Sir please Hindi videos banaye

[@shomusbiologyofficial]

Will make it soon

[@saisatvika1218]

It was discovered in 1957

[@guneetkaurtutorials9526]

It was discovered in 1956 by Arthur Kornberg

[@heerachoudhary2885]

Thanks

[@shomusbiologyofficial]

You're welcome

[@saraalaa7740]

thank you!!!

[@shomusbiologyofficial]

You're welcome