DOCTOR reacts to CELLS AT WORK! // Episode 10 // "Staph Aureus"

We're back in the world of your human body and your Cells at Work / Hataraku Saibou! I breakdown scenes from episode 10 from a real doctor's perspective. I'll be reacting to scenes and attempting to share a little bit more about the science behind the best science anime.
We learn a bit more about Staphylococcus Aureus, coagulase, phagocytosis, monocytes and macrophages!
This is more of a lighter episode, and recaps a lot of things we've already seen in the series.
This is part of a series reviewing Cells at Work, you can find the whole playlist here:
• Doctor reacts to Cells...
You can watch Cells at Work! here:
crunchyroll.com...
If you enjoyed this please check out my other reviews of Medical TV dramas; House MD, Scrubs, The Good Doctor, Grey’s Anatomy, The Resident and ER! And also I did a series on Marvel movies too, more on that soon.
Instagram: / drhopesicknotes
Twitter: / drhopesicknotes
FB: / drhopesicknotes
Clips used under fair use (education and review):
THANK YOU FOR NOT COPY STRIKING THIS VIDEO SO I CAN CONTINUE TO USE THESE GREAT SHOWS FOR EDUCATION AND REVIEW.
ALL Cells At Work! Clips owned by Kodansha / Kodansha USA and distributor Sony Music Entertainment (Japan) Inc.
Phagocytosis clip from Mr Riddz Science:
• Phagocytosis Under the...
Coagulation graphic:
www.paeds.co.uk...
Megazord clip:
• All Megazord Transform...
Thank you to all the artists that make their music available for these videos:
Song 'Escapists' by The AutoDisko
Song 'First Day' by Huma-Huma
Song ‘Finding Me’ by Eveningland
Song 'The Stalker' by Hainbach
#doctorreacts #doctorwatches #cellsatwork

[@grimrobin696]

Broke: Getting the twist spoiled because you see it somewhere Woke: Getting the twist spoiled by becoming a doctor

[@cheesecakelasagna]

It do be like that sometimes

[@justsomeguywhoneverdies9210]

Nice

[@Wuscheli0]

I had to stop reading Wikipedia articles about historic figures to avoid Assassin's Creed spoilers.

[@cheesecakelasagna]

@@Wuscheli0 I had to stop my christianity to avoid bible spoilers.

[@seqka711]

@@cheesecakelasagna I had to stop taking history classes to avoid Fate spoilers.

[@Blastmn]

Not gonna lie, no matter how long I wait, I still love to learn things about subjects I never want to go in

[@taisukethetiddyconnoisseur2581]

Nice ass

[@terrywilliams157]

Same

[@amnesiadan160]

Well said

[@giboit.]

Same.

[@TempRawr]

Gives us much respect for those who do go in it. A little bit of knowledge for us to appreciate all the knowledge and work put into this stuff. Like being a doctor and education youtuber!

[@smith7602]

"My favorite cell in Cells at Work, the Macrophage." Ayy you found your waifu.

[@ravenstone3436]

Ara ara

[@bluesoda6379]

So proud of him

[@CryingZombie666]

My waifu in CAW is Natural Killer cell. She's so ripped and hot :D

[@adt4864]

He said it's because of the long swoooooooord.

[@peterlemieux7614]

It's Inoue Kikuko. How could you not fall under the spell of her wonderfully lyrical voice?

[@telekiller7]

Doctor A: "I've discovered a new bacteria, but I don't know what to call it" Doctor B: "Well, it looks like some round, yellow grapes. You can call it that" Doctor A: "Nah, it needs more pizazz... What if it was that, but in Latin?"

[@DonoZeek]

Pizazz. Whatazz

[@ayyylmao101]

_Or Greek~!_

[@shiftygirl6434]

pizazz hands

[@mrflip-flop3198]

Med student: And this bacteria is called............. *Wtf is this?!?*

[@nitorishogiplayer3465]

In Chinese it's literally just that. 金黃葡萄球菌 (Golden yellow grape spherical bacterium). No "make it Latin" fuss there.

[@benjaminlgur]

The size of the weapon represents the size of the immune cell. With the small t cells using their fists. Slightly lager nutrohils using knives and macrophages using large stuff cuz they big.

[@DrHopeSickNotes]

Oooo I like that

[@Hadaron]

Dr Hope's Sick Notes Did... did you just heart your own comment?

[@kennjt5015]

now I'm more amazed by how attentive they are to details. Awesome!

[@zodiak123]

@@Hadaron always love yourself

[@DrHopeSickNotes]

Whoops- I was supposed to like the original comment!

[@GyroCannon]

> Knows that the monocytes will become macrophages before the big reveal See, this is why you go to med school You learn all these facts so that you can know what's gonna happen in a medical anime

[@damienburroughs2119]

"SO I have some idea of what this cell might be, buuut let's wait and see." aka: I have no bloody idea what that thing is.

[@DrHopeSickNotes]

Correct. Good technique I learned from doctoring :)

[@franciscarodrigues3629]

As a developer I support this motion

[@bbd121]

@@DrHopeSickNotes I see Hypervisor administrators and English doctors go to the same communication classes. ;D

[@marvinchaves1252]

I also use this 😅

[@cardenevans6238]

Im guessing syphilis

[@blacksword2468]

I love how he spoils the twist in the episodes just using his vast knowledge in the subject and his video interpretation. This just shows how great details this show went into. Thanks again for another deep dive in "cells at work".

[@monjurakil2392]

*Dr. Hope:* **explaining Coagulase** You might think, oh why the bacteria would want to do that. *Me:* **sweating nervously** Yes, that was definitely what I was thinking.

[@DrHopeSickNotes]

I thought so

[@wessltov]

I actually had a thought that maybe it want a patch of skin like it was used to outside the body. I think the fact that you waited for Prof. Hope to explain with his knowledge makes a lot more sense than homesick bacteria

[@user-pr6ed3ri2k]

@@wessltov cool

[@SM......]

I'm showing my age when I grin at that Megazord comment

[@rastko7261]

I'm 17 and I love those old Power Rangers/Kamen videos just for how badly they are done by today's standards.

[@orangejuice393]

Hahaha same here!

[@zjzr08]

I mean even kids today still know what a Megazord is in concept to be fair. :p

[@MtnNerd]

@@rastko7261 We knew how bad they were back then lol

[@AkinomaHNU]

@@rastko7261 They were bad back then but at least they were executed better than those of today.

[@cheese_man4952]

Your editing has improved a lot since the first episode, love your vids

[@taisukethetiddyconnoisseur2581]

Nice ass

[@PMnoam]

you should react to the anime of dr stone has a lot of science as well as being very good.

[@hazelreys1103]

@@PMnoam Yeah, but Dr. Stone is definitely more chemistry than biology.

[@lalaicyling8429]

@@hazelreys1103 More like physics

[@ghost-wl3pm]

@@taisukethetiddyconnoisseur2581 ...

[@richardlsp7670]

Your explanation to how macrophages work to kill bacteria reminds me of a detail about the macrophages in Ep. 7 (cancer). There is a scene in which the macrophages are cooking something having an arm, this maybe represents that the macrophages are digesting a bacterium. And the arm looks like the arm of a Staphylococcus Aureus, so probably they have just finished a battle before that lol.

[@taisukethetiddyconnoisseur2581]

U know I'm actually ESCANOR. It was noon last mon day and I punch my brother.. he nosebleeded.. meaning I get stronger as day rises. Nobody can beat me u know that ... WEAKLINGS.. Praise the sun..

[@tricksor6589]

@@taisukethetiddyconnoisseur2581 ok

[@Evarace]

@@taisukethetiddyconnoisseur2581 weird flex but ok

[@dx.feelgood5825]

@@taisukethetiddyconnoisseur2581 Praise the sun, my man of culture

[@e3210-y7o]

@@taisukethetiddyconnoisseur2581 . Pee is stored in balls

[@mirandabee2323]

*Staphylococcus Aureus starts doing the oujo laugh* Oh my gosh they made her a princess. I'm sobbing.

[@OverseerMoti]

But ojou laugh here is still lost by the *ara-ara energy*.

[@gokbay3057]

I mean "she" is golden so...

[@CrazedComposure]

Maybe because she comes from a big, tightly knit "family"? Like an old noble house

[@heybestie6749]

OMG lol

[@innertuber4049]

You are an amazing teacher. You'd do great as a professor, mentor, or any type of medical leadership profession. Thank you for the videos, they're only encouraging me to go down my track to med school.

[@maraailacarmona5874]

Was that spiral bacteria a Leptospira? I think it is because Leptospira is an obligate aerobe

[@zetsubouda]

It sure has the look down en.wikipedia.org/wiki/Leptospira#/media/File:Leptospira_interrogans_strain_RGA_01.png

[@QuesoCucuy]

could be. it looks like the squiggles it had drawn on its arms too

[@Tamaki742]

How the fuck did this human get leptospirosis?

[@MischievousBastard]

@@Tamaki742 Rat pee is a popular vector, and it's a notable occupational illness of refuse collectors. Bin men pick up bin bags that a city rat has peed on, then come down with a very vile disease indeed.

[@Tamaki742]

@@MischievousBastard I'm well aware of that, Indonesia had sudden cases of leptospirosis several years ago. But that said, we can assume that the human the cells live in is possibly a garbage collector?

[@SonGoku-777]

Im not first, Im not last, But when Dr hope watches "cells at work", I click fast

[@guimts8881]

This is poetry on a whole new level

[@superduperjoi6800]

Lololi

[@JIYkp]

Dr. Hope: I use my medical degree to spoil anime plot twists.

[@felmargego2534]

He has too much power!

[@gbreuil1]

Always a pleasure to see the doctor analyse waifu swat maids

[@Moepowerplant]

"Like any bad dude they like to tell you what their master plan is." How much more simple would it be if all criminals did the same?

[@mightygamer5550]

Two red blood cells and two platelets are talking one red blood cell says “I heard you guys finally tied the clot” The other says “coagulations!!” I’m sorry I had to say it

[@ArkaneOmega]

im giving you a like, but i just want you to know. I didnt like doing it.

[@allankanegalian6401]

i will applaud you, but i will also slap you.

[@sarerusoldone]

that was horrible, i love it

[@deltav9784]

I love how these replies are all liking and disliking at the same time. Terrible.

[@Dakota__69]

Thanks, I hate it

[@c5l6t4]

"take care of yourselves" is probably the best way to close a video about cells

[@laartje24]

"Take care of yourcells"

[@mrflip-flop3198]

"Love yourcells"

[@XenoflareBahamut]

6:45 PTSD got triggered

[@laartje24]

How is that triggering your ptsd? It didn't trigger mine but I know triggers can differ between individuals.

[@t.thomas8919]

I agree but damn... it was funny. XD

[@BicyclesMayUseFullLane]

Coagulation cascade is... something. Now add the pressure of university education on top of that. I'm just glad that I never had to take biology or anything related to that in high school or university.

[@jaaltheangel1952]

Man I can’t wait until you get to the finale of this anime👀It is gonna be EPIC!!

[@CryingZombie666]

Both the finale and the OVA too!

[@luqdude]

@@CryingZombie666 and then we're getting a season 2 so he better watch that

[@CryingZombie666]

@Luqman Headley He will watch it, but in the meantime, he *needs* to watch the brilliance of Black Jack!

[@dorianwilde]

OMG I can't wait either. Been waiting so long for him to get there (took me a day of binging LOL).

[@alicorntrash1262]

I was so sad with some of the things that happened there 😢

[@siechamontillado]

11:17 "Axe thing?" My good sir that is a halbred! "Axe-thing," my god the state of British education nowadays....

[@ArcheoLumiere]

Aussie education my friend

[@CryingZombie666]

It's halberd* , dude.

[@SmNBahamut]

Imagine what education might look like if we didn't have guns.

[@fllthdcrb]

A possible response from Dr. Hope: "Dammit, Jim, I'm a doctor, not a medieval weapons expert!"

[@zerocalvin]

Staphylococcus Aureus is my favourite "monster of the week" of Cell At Work

[@burrotails]

Watching this episode while having pneumonia is something else. My cells are working so hard right now 😭🥺💕

[@tristanmilner9511]

So Monocyte's can turn into Macrophages? Que the Sailor Moon transformation.

[@windarchermadeanartchannel984]

Yes, Yes indeed

[@damienburroughs2119]

Fighting bacteria by Moonlight, Drinking tea by Daylight, Cleaning my Giant Mace for the next fight, ...sorry, I'm going to go sit in the corner now...

[@Ralpherzz_meowmeow]

I may not know what bacterium this is bit I believe you guys may know it! Me: you expect too much from 12 year old...

[@Wolfrich666]

im 27 and i dont know...

[@orangejuice393]

I loved it ahaha

[@Ralpherzz_meowmeow]

@@Wolfrich666 I believe its cuz you didnt study medical currently I am still learning... Im not learning grade 8 didnt start yet...

[@tharushafernando4410]

@@Wolfrich666 Bacteria is Plural and Bacterium is singular.

[@lasrber]

I legit got crunchy roll just to watch this show because sicknotes is so awesome. Now I geek out over cells and drive my coworkers crazy with trivia

[@hzzzzz1]

lasrber you should check out Dr. Stone

[@dragarok]

@@hzzzzz1 yh i started watching Dr. Stone today and honestly,im hooked.

[@PanthereaLeonis]

It's on crunchy roll? Well, now you know where I'll be the next few hours...

[@kldinsidebias6742]

lasrber same

[@TheLocomono9]

Same actually but on funimation

[@Kravax]

You get extra points for the Power Rangers reference, Doc 👍

[@Nadia1989]

I laughed really loud. And then I cried. Man, I'm _old_

[@Natsukiiroi]

LOL Zyuranger

[@jpy5349]

Finally, yes! I've been waiting for this!

[@Sparrow_Bloodhunter]

now we wait another month for the next episode.

[@Kaiyo_Azuma]

SAME

[@damienburroughs2119]

be nice to him, some people actually work for a living. (not to make fun of or put anyone down, it's he is a doctor, this is a show about the innerworkings of the human body, and I am disabled so I pretty much mooch off of my parents since I can't work anymore...against my own wishes...god I miss working...

[@jpy5349]

@@damienburroughs2119 I didn't mean it in a mean/rude way, I wanted to put out an excited emotion but didn't quite achieve it. I very much understand that he's a very busy doctor. I apologise.

[@Kaiyo_Azuma]

@@damienburroughs2119 It's not that I'm trying to to be mean and say that "oh my god why has it been so long since you uploaded a video about Cells at Work!" and I'm sorry if I come off like that, it's just that I'm really excited to watch another episode. Again, I'm sorry if I come off as impatient.

[@ConManAU]

12:00 Are those red cubes from a copy of Pandemic? Are we going to see a board game review at some point?

[@Rikativity]

OMG I'd wondered that too! Dr. Hope, if you do have Pandemic, I'd love to see a review/let's play with your colleagues! :D

[@PanthereaLeonis]

@@Rikativity Oh yes! He should totally get some colleagues over to play Pandemic. Or maybe he should collab with Dr. Mike on that. I can see it already, a group of various medical professionals, playing a game about disease.

[@laartje24]

@@PanthereaLeonis Yeah but isn't he in the UK and doctor Mike in the US? That might become a bit hard for them.

[@PanthereaLeonis]

@@laartje24 Be that as it may, but it still sounds like it would be awesome.

[@ayyylmao101]

11:55 The macrophage he cut out looks like it's screaming in agony, lmao. You alright there, doc?

[@Chiasa7]

Grab your notes everyone, class on. Make sure you note it down as it's almost the end of semester and final is near.

[@chibi_reiko]

I know that feeling! Finals is waving!😲

[@jon.9209]

Not gonna lie, this anime made immunology and hematology so much more fun for me 😂

[@MutheiM_Marz]

take care of your cells ??? i heard that....self or cells or both??

[@OcioCamaraMx]

I love how not even 5 minutes in and he already spoiled the "twist" in the episode!

[@KoriandrOfTheStars]

When you realize the Myeloid root is basically an Eevie and the cells that differentiate/descend from it are basically Eevolutions LOL

[@natalybasora9769]

I love this anime, and as a Microbiologist who loves bacteria this show is amazing to me! Very quirky and intuitive the way they present many topics and explain them in such a great way!

[@fookme23286]

I just got done with my college Microbiology course and an Anatomy course last semester. I also watched this show as it was on first run, and I gotta say, holy crap were the creators of Cells at Work on their game! Everything that was shown in the show is spot on to what you would learn going into Med/Nursing School. Doctor Hope, I am so happy you showed this off!

[@makeda6530]

**distant screech** High five Doc, new content! ╭( ･ㅂ･)و Your cell map is much less intimidating than that coagulation cascade you overlapped.

[@zorak6192]

It was the coagulation cascade

[@makeda6530]

@@zorak6192 Thank you, now I can fix my comment ╭( ･ㅂ･)و ｸﾞｯ !

[@blacksun3884]

It's amazing. One day future medical doctors will look back on their school years and go "Yeah, I learned Immunology by watching anime".

[@marvinchaves1252]

Doctor: "my favorite cell is the macrophge" Me: i see youre a Doctor of culture as well 🍷😌

[@meLuvdarkrai]

Just binged watch the entire 10 episode reviews and even as someone who has no medicine background, I REALLY love your videos and all the clear explanation and break down of each word and meaning of the anime. Thank you so much for doing this!

[@Neesauniverse]

I love how you guess what happens before it does and that really tells me this show is truly even more accurate than I orginally thought which makes it even better

[@ma.angelamamaril6286]

I already watch the whole series but going through your videos made me understand it more. New subscriber here. :)

[@DavidPTUS]

Same here. These episodes complement the show so well. I understand more about the events in the show and the show in general from watching these episodes. Now I am waiting for season 2 and his take on the remaining episodes of season 1.

[@Geral1002]

awesome episode doc! i'm looking forward for the "hemorrhagic shock" one

[@humanatee6639]

Yay cells at work is baaaaack!

[@kirztiejoseph6624]

Welcome back Doc😍😍. I have never clicked a video so fast,🤚 to God 😇😇

[@Shearper2]

woooh! another cells at work episode. always glad to see these. didn't know monocytes could become dendritic cells as well. learn something new everyday :)

[@theslightlytiltedcat]

When this first came out, I just watched for fun. Now that I've re-watched it for many times and have started reading information regarding the terms used on each episode, I feel like some sort of medical student or something. XD

[@johnbritinburg8276]

The only reaction channel to be both educational and very note to detail.

[@MrKlausbaudelaire]

I confess I squealed when I saw my notification pop this up.

[@rf3162]

I really hope you continue on with the next 3 episodes of season 1. I love how your comments are really adding another level of depth and understanding to making sense of what would otherwise may be interpreted as the understandings of reality according to a madman. Also season 2 has been announced for July 2020. I can't wait!

[@althea7200]

miss macrophage is best girl she's my favorite too

[@lolmeme69_]

I see you are a man of culture.

[@CryingZombie666]

My best girl is Natural Killer cell though. Those biceps are hot!

[@imafemale4365]

Althea but of course!

[@RedHairdo]

An MMORPG based on this would be so perfect. Class changes and everything, RAID bosses being major infections... The list goes on.

[@guizarbayardoemmanuelisaia1718]

Need the last 2 episodes! You're amazing

[@kryatme7833]

The second I saw this, I had to immediately click. Stopped my Anatomy homework to check out our friend the RBC. I'm so excited you're continuing with this series!

[@Reinscape]

2nd season is currently on the way for airing This is a very long waiting but glad to see this reaction video once again for educational purpose XD

[@mondirapaul]

Dr hope, i gotta say, youre one of the only reasons why im passing medschool. Watching you watch and explain cells at work is my favourite study break activity

[@riality7302]

I can't wait for your reaction to the next episode! I really enjoyed learning more from you

[@adt4864]

*sigh* thanks, I hate it.

[@kirstyshadowdancer5095]

I love watching you gush over this cartoon. I know on episode 1 you were like "Oh this will just be a kiddy show that explains the basics" but Noooo. I love how impressed you are each time you see something that makes sense from a science perspective.

[@Ace5665]

When I first saw the monocytes turn into the macrophages I laughed like a lunatic

[@twilight_lupinesilva4691]

I kept waiting for the Killer T Cells and B cell to appear, but when the Macrophages talked about being fashionably late, I remembered that T cells don't appear to an immune response until after the macrophages do, and I was hoping Killer T would show up to realize the fight is already over.

[@kaynath4274]

I wonder if Dr Hope makes his students watch Cells at Work for his medical lectures. 😂😂😂😂😂😂

[@k48yle]

Doctor Hope, you certainly make learning about biology a lot more fun and interesting!

[@daveneely8692]

You're running out of room again on that page! Super enjoyable to watch as allways.

[@MaserXIV]

It's been a good while since I watched through Cells at Work, so it's fun to go back, little by little, and relive the episodes. And learn a thing or two, as well!

[@Amonimus]

I've been waiting for this. I need an adult to explain these words.

[@MrNewyen1]

Being a doctor is like knowing all the spoilers to this series.

[@AidynNichi]

I love this series!! Thanks for giving us your take on it :D

[@crazyeeveelady3636]

I always get a little spark of serotonin when I see these videos in my subscription feed

[@rely_able]

Yayy more Cells at Work! I actually decided to watch the anime because of your videos on it!

[@abingus8509]

There's so much attention to detail in this show, watching your reaction/breakdowns is pretty eye-opening.

[@Kumahachi8]

Oh, goodness. The nostalgia I felt when you likened them to the Megazord. Haha!

[@Fammangalover]

I've never seen someone watch an anime so slowly. Especially one that can be easily bunged watch. But he takes his time which is commendable.

[@ReptilianTeaDrinker]

I'm not looking to go into the medical field, but I love learning about this sort of thing. Very interesting! I enjoy your reactions and explanations. :D

[@TemporaryINTER135]

Good work, your almost to the finale where the world almost ends

[@stephaniest.5336]

Best way to start a Friday. Watching my favourite doctor react to the Cells at work's "How to play whack a mouse with style" episode. As always great reaction and explanation of episode and i like how you add in details such as the schematic of how the coagulation factors lead to the formation of fibrin.

[@r00k_mk2]

Not sure if anyone else has commented on this but you can also see in the background in multiple episodes the macrophage is stirring pots with the limbs of the germs hanging out of it. I would think that it is a nod to them digesting it?

[@seanabenes2670]

I’ve learned more biology with this commentary than my actual classes 😂

[@MilD_Voices]

This probably the first time I ever got spoiled about something in an anime episode, and not get mad about it. I love learning like this.

[@WideoWatcher19]

Brilliant as always, Dr. Hope! Keep up the great content!

[@veldandi2443]

You really, really explain things the way people like us(who is not a medical related experts) too understand these kind of things. Amazing.

[@oldaccount_encounter878]

Cant wait for doc to reach episode 12-13 Cuz DANG its emotional I cried

[@marcusreading3783]

The Macrophagies are the best characters. I've always loved characters who can remain smiling and unphased while dishing out beatdowns to the badguys.

[@MilanMilan0000]

Everytime I see one of these I IMMEDIATELY click on the video. Love your channel!!! You somehow made me be interested in medicine.

[@cody7556]

Never stop making these videos please. I'm learning a lot

[@user-hp6jn8zj7b]

Finally! I missed this so much

[@KilledWithStyle]

oh man I am going to enjoy episode 12 (and 13) when he gets there. I cannot wait.

[@JJtoob]

I love the Cells at Work breakdowns.

[@GoldenPhi1]

Please do the final two episodes in one video. It is a two part episode, so doing episode 12 on it's own wouldn't make much sense. I am enjoying this series as always.

[@pokuichi3028]

He is knows his stuff so well he tells us spoilers before he even sees his own spoilers! XD

[@maryjoseoliveirabieler6554]

Yes love your reactions. You should react to the Canadian Medical dramas Saving Hope and Remedy. Please like so he'll see it.

[@karloraras8631]

Guys with a suit is Monocyte (intravascular) and turns into Macrophage (extravascular). As for the corkscrew shaped bacterium, i'm guessing it is Treponema. Man, this body is a mess! ✌😅

[@maximumdon7637]

Well, you're probably the first guy in the comments to have a guess at what the unknown bacterium might be. I have no clue if you're right or not (Though looking it up, it looks more like a spiral than a corkscrew), but good job with the effort!

[@karloraras8631]

@@maximumdon7637 well, it can't be Borrelia since most of the spp. are either anaerobic or aerotolerants. My other guess is Leptospira but then again, I might be wrong.

[@luccanelson768]

You should do a reaction to Kurzgesagt‘s recent episode on the Compliment system!

[@andrewang2174]

watching this anime with a real doctor is more fun than just watching it alone.

[@michaelgarcia6919]

Cant wait for the next video

[@Syiepherze]

7:22 Dynamaxed Staphylococcus

[@swordcrab3181]

I love the macrophages, just being sweet and full of cheer as they brutally destroy every pathogen in their way. So wholesome.