Olink Podcast | Ep 12 Mechanism of Action of an SLGT2 Inhibitor

Welcome to Olink Proteomics in Proximity Podcast!
Below are some useful resources from this episode:
Highlighted publication: Zannad F, Ferreira JP, Butler J, Filippatos G, Januzzi JL, Sumin M, Zwick M, Saadati M, Pocock SJ, Sattar N, Anker SD, Packer M. Effect of empagliflozin on circulating proteomics in heart failure: mechanistic insights into the EMPEROR programme. Eur Heart J. (2022) 43(48):4991-5002. doi:10.1093/eurheartj/ehac495: academic.oup.com/eurheartj/ar... PMID: 36017745; PMCID: PMC9769969: www.ncbi.nlm.nih.gov/pmc/arti...
Review paper of research by Voltar Longo and David Sinclair on longevity and aging, mentioning sirtuins and mTOR. Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 onlinelibrary.wiley.com/doi/1... 22. PMID: 25902704; PMCID: PMC4531065 www.ncbi.nlm.nih.gov/pmc/arti...
Here is general information about Empaglifozin (Jardiance) on Wikipedia: en.wikipedia.org/wiki/Empagli...
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In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink Proteomics assay technology called the Proximity Extension Assay (PEA), and more information about the assay and how it works can be found here: bit.ly/3Rt7YiY
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