E1 and E2 Reactions: Crash Course Organic Chemistry #22

We’ve spent the last few episodes talking about substitution reactions, but now it’s time to talk about a related type of reaction: elimination reactions! Elimination reactions are super important because they are the main way we can make compounds with double and triple bonds in organic chemistry. In this episode of Crash Course Organic Chemistry we’re going to cover… a lot, including a review of substitution reactions, E1 and E2 mechanisms, Zaitsev’s rule, and more. And of course, we’ll finish with some practice problems.
Episode Sources:
Chemguide.co.uk. Dehydration Of Ethanol To Give Ethene. [online] Available at: www.chemguide.co.uk/mechanism... [Accessed 21 September 2020]
Hornback, J. M. (1998). Organic Chemistry, Brooks.
Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
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So you post this the semester after I finish organic chem smh

[@DoodlesintheMembrane]

I’m so excited that Crash Course is exploring organic chemistry reactions

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I'm currently studying organic chemistry and this really really helps me. Thank you ma'am and the crash course team!

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The big picture issue here is... Why would you want to eliminate alcohols. 🤣

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i have a report in chemistry in few hours and currently cramming our presentation. Elimination is my part in the reaction mechanism, thank you for this video!

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I have to watch this a few more times. Also what about Wall-E reactions?

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Why do we need an antiperiplanar arrangement of hydrogen and bromine for the E2 reaction to happen?

[@bohaz2262]

When the hydrogen atom and the bromine atom are at antiperiplanar position, they are at the same plane. This aligns the 2 sigma bonds that becomes a pi bond. Eg. The double bond in ethene during the elimination of ethanol.

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11:45 the carbocation is resonance stabilised so shouldnt it be E1

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I have a question, the video very clearly explains Zaitsev's rule but at which point do we have to account for Hofmann's rule tho?

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we have e1 and e2 reactions, but what about the e3 reactions, aren't those the ones where a whole human being reacts

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