Effects of Exercise on the Brain, Animation

(USMLE topics, neurology) Effect of aerobic exercise on cognitive functions, depression treatment, and neuroplasticity, mechanisms involved. This video is available for instant download licensing here : www.alilamedicalmedia.com/-/g...
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Voice by: Ashley Fleming
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Apart from body fitness, physical exercise also has beneficial effects on the brain. A regular routine of aerobic exercise can improve memory, thinking skills, moods; and have protective effects against aging, injuries and neurodegenerative disorders.
It is noteworthy that these effects are specific to “aerobic” exercise - the kind of exercise that accelerates heart rate and respiratory rate, such as running, cycling, swimming... Non-aerobic activities, such as stretching or muscle building, do not have the same effect. The effects appear to result from increased blood flow to the brain and subsequent increase in energy metabolism. A certain degree of intensity is required to achieve the beneficial outcome.
Aerobic exercise increases the production of several growth factors of the nervous tissue, known as neurotrophic factors, among which BDNF, for Brain-Derived Neurotrophic Factor, has a central role. BDNF exerts a protective effect on existing neurons, and stimulates formation of new neurons from neural stem cells in a process called neurogenesis.
BDNF appears to coordinate its action with at least 2 other growth factors: insulin-like growth factor 1, IGF-1, and vascular endothelial growth factor, VEGF, whose expression levels also increase following aerobic exercise. BDNF interacts with IGF-1 to induce neurogenesis, while VEGF stimulates growth of new blood vessels, a process known as angiogenesis. Together these processes improve survival of existing neurons, produce new brain tissue, and constitute the brain’s enhanced plasticity that underlies the exercise-induced protective effect against aging, degenerative diseases and injuries.
Changes in BDNF levels are observed throughout the brain but are most remarkable in the hippocampus, the area that is responsible for memory retention and learning. In fact, regular exercise has been shown to increase the size of the hippocampus and improve cognitive functions.
While acute exercise, defined as a single workout, can produce significant changes in BDNF levels and subsequent improvements in learning performance; a regular exercise program progressively increases BDNF baseline level and make its response steadier overtime. It appears that some cognitive functions are enhanced immediately after a single workout, while others only improve following a consistent exercise routine.
The immediate effect of acute exercise is most remarkable on the body’s affective state. A single bout of exercise can promote positive emotions, suppress negative feelings, reduce the body’s response to stress, and sometimes, after intense exercise, induce a euphoric state known as “runner’s high” sensation. These effects may persist for up to 24 hours, and are thought to result from exercise-induced upregulation of several neurotransmitters involved in mood modulation. These include:
- Dopamine - a neurotransmitter of the brain reward pathways;
- Serotonin, commonly known as the substance of well-being and happiness, whose low levels in the brain have been associated with depressive disorders;
- Beta-endorphin, or endogenous morphine, an endogenous opioid;
- and anandamide, an endogenous cannabinoid, a substance related to psychoactive chemicals in marijuana. Endogenous opioids and cannabinoids are involved in pain modulation, stress and anxiety reduction and are believed to underlie the “runner’s high” sensation.

[@Alilamedicalmedia]

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[@campeonesmundiales]

Thanks

[@christianwellness4363]

When I start to run or do long bikes I force myself during the beginning but after a couple miles I start feeling euphoric and motivated to keep going and feel amazing 💪

[@bobbyc978]

completely relatable sometimes i don’t wanna go near the gym but 30 min in it’s my paradise

[@patriciaf.v.8889]

The last time I rode a bike, I felt tired but okay. Then, when I got home, suddenly I felt incredibly unwell, so bad that I couldn't even get to the living room as I couldn't stand any longer. I left my bike on the curb and laid on my porch, worried I was going to need a doctor but with no strength at all to call one. It turned out my blood pressure dropped so much and suddenly, it happened before, but not as bad as that day. As my head was down in a few minutes I felt a little better and able to put a pinch of salt in my mouth. I used to love riding a bike, but after that day, I got scared 😢

[@ven.skeeey9]

I have been working out/doing cardio everyday. I felt stronger and I feel relief. The feeling feels good and It helps your brain so much.

[@copingflower1909]

I've been an animator for 3 years and I will say the brain is such a curious part of our body cause it only takes practice and you can do stuff you never imagined yourself being able to achieve in just under 3 tear myself I'm already doing animated projects that are closing in a level of quality and amazment I got by watching animations by some of my favorite animators

[@francisromero79]

I have fibromyalgia and going to the gym for treatment is the biggest reason why I'm the only one who's not suicidal like others who suffer.

[@sugandhadogra1781]

Hats off to u ,i have d same condition. How do u do now ?

[@redwarrior2963]

I've stopped running since I was in Middle School and I just don't feel like I can do things and learn incredibly faster than others anymore. Thx for sharing this video! I'll try more aerobic exercises from now on.

[@ChroniclesofAJ]

jump rope, walking, or playing basketball, tennis, or handball as a fun alternative choice to running

[@Geveretzah1]

How is it going?

[@genericdeveloper3966]

cardio is what got me through college.

[@alanguages]

@@ChroniclesofAJ Dancing and swimming are also great. Anything with notable aerobic activity.

[@ChroniclesofAJ]

@@alanguages yes thats a good one

[@markalagdon898]

As someone who goes to the gym to lift I disagree that resistance training does not give the euphoric feeling aerobic exercise does. I always feel energized and positive after a good workout.

[@gunjanjain7274]

Thank you for this valuable knowledge. 😊

[@pillbox1240]

I will say I’m really depressed if I don’t exercise. Triathlon training for 40 years has kept me from committing suicide.

[@kimdaniel5511]

Me: I hate running... Me after watching this: I’m ready I’m ready I’m ready!!!!

[@1kTroopKoopas]

Did you go yet? 😂

[@kimdaniel5511]

@@1kTroopKoopas nope 😅

[@1kTroopKoopas]

Thanks for replying! I'll check again in 2 more years

[@kimdaniel5511]

@@1kTroopKoopas lol

[@xuhan3781]

Wonderful!!! Thanks a lot!

[@PraxisOfHealthBillFaulkner]

Excellent! Thank you for sharing. Blessings!

[@shaikhaaves6645]

That's Amazing!!!!!

[@aliabdelnaeem3438]

Very nice video thanks

[@mynameisjeff9124]

How is strength training not an aerobic experience? My pulse goes through the roof when lifting weights. It depends on the trained muscle group how high it goes, but I reach a pulse of 160-170 BPM when training legs, so something doesn’t seem right

[@JarkkoKokkonen]

You need to look up the difference between aerobic and anaerobic exercise.

[@bobbyc978]

prob referring to power lifters if u train heavy/moderate no breaks all volume40-60min cardio is a breeze

[@theroyboy4573]

every exercise can be aerobic as long as its intensity is high enough since its about increasing heart rate and breathing by alot

[@scarred10]

if you go fast enough and long enough sets your HR will be pretty high but the increased vascular resistance during strength training means the heart cannot fill sufficiently for it to be a good cardio workout.Its also not done for long enough continuously.

[@shahrulnizam3770]

I would totally disagree promoting only cardio...neurogenesis still occurs during weight training even after the session...by doing cardio, the main driver for neurogenesis is triggered by mainly bdnf while weight training is by igf 1...simply combine both to get the best of both....but if the option is limited to only one,would you rather be skinny and smart or would you rather be jacked and smart a.k.a. Gigachad?

[@Premium_ZoomerTrader]

Never began for gym copecels

[@calebp1423]

This guy gets it

[@alanguages]

@@Premium_ZoomerTrader The op is correct though. That is how to get in the best shape. Another important aspect, which is ignored would be stretching. Diet is effectively just as important I would say for the brain.

[@iamteezytv1424]

This was a great video‼️👍🏾

[@user-mg5nb4kp2u]

I like all of the video

[@SalmanKhan-sk1lu]

Amazing

[@talitalaurie5727]

I like all of your videos!

[@Rehan-bs6uf]

Sir, I have parkinson's desease since childhood, how to treat it?

[@11fasteddie]

Would like to participate on any volunteer/join research, if any pls respond, thanx.

[@sagivalia5041]

Are the exercise types of jumping jacks, high knees and the such possess the same effects? They are sorta like I would name it a flexible intensity training.

[@BiraDaniele]

As long as they raise your heart beat rates, they are good

[@sprucefan4379]

Yes, jumping rope is also a great way to do cardio.

[@hannahjess-annferrera5040]

I'am preparing for my board examination. I do homework out it feels good but when my bf ask me to do biking with him after Review Center class so we could have bonding session and a same time do my exercise routine. I notice i do perform better in solving problems. And I easily understand our lesson unlike before

[@reg.pharmacistbiswajit5839]

Thank you so much mam

[@Alilamedicalmedia]

Most welcome 😊

[@1ONEO]

Does it help angiogenesis?

[@antsavs1705]

I heard 20 minutes of exercise will have similar effects. Has anyone else heard of that?

[@CocoChanelle-1]

Yes it does if done at least 3 times a week.

[@soul2soul4]

@@CocoChanelle-1 It seems you only get results when done consistently

[@CocoChanelle-1]

@@soul2soul4 that makes sense. The more you exercise you pump good oxygen into the brain. For some reason the increase in dopamine increases sex drive too.

[@alanguages]

It has to be high intensity exercise.

[@scarred10]

@@alanguages just moderate intensity is plenty,talk pace is enough.

[@Phoenix-ov5gg]

Moderate to high intensity, what is that as a max heart rate percentage? Because above 70% (intense) it is anaerobic exercise.

[@genericdeveloper3966]

If you super set, weight lifting is like cardio, but be careful you don't overdo it as you will be more fatigued.

[@minetteestrada4639]

That’s right! 👍

[@scarred10]

it can never be like cardio because the duration isnt long enough and the blood pressure too high to have the same benefits

[@aliabdelnaeem3438]

Woooooow,it is very important info for me as chess player get redy for master title thank you

[@ambientscience2951]

i also play chess

[@josephjoestar953]

I only really play lightly but I used to play it online daily

[@julianfalciola5237]

I wonder going for a walk a few times a day?

[@pharmacysupreme5629]

I am from India and it is a very good video sir. I have one question please reply sir. During aerobic exercise what is the scientific reason which enhances the serotonin release in brain ?

[@sb350allday]

You shouldn’t push him for an answer

[@MrGoodeats]

Likely to aid in responding the threatening stimuli that caused the “exercise” Remember when asking why questions about the human body to take it back to hunter gatherer days. Only reason for exercise back then was to run from a potential threat

[@OwlCMedicine]

@@MrGoodeats or to run for games which was training for hunting another times running was necessary. And hunting was never don't alone until we had guns. so there is likely a connection there. Group oriented exercise would be evolutionary appropriate and social engagement benefits from serotonin. That's my current hypothesis anyway. The programing for what transmitters are released for what reasons in what settings is very old and difficult to pin down.

[@SlicedSlappy]

Is it correct to say that if I stand on my head then blood flow will increase to my brain and I can get the same results?

[@Alilamedicalmedia]

Unlikely, passive blood flow may not do much. The brain needs to be active and require that flow, only then it makes changes to adapt to higher blood supply.

[@raczyk]

@@Alilamedicalmedia what a blunt head stands for hair growth?

[@user-bd4bo4tb8u]

@@Alilamedicalmedia So headstands and inversions in yoga are bs in their claims?

[@michaeljackson8002]

It causes blood to accumulate not to flow, which means fresh oxygen carried in the blood will not necessarily reach the brain, thus having the opposite desired effect.

[@scarred10]

the blood goes to your face and head but not brain because there is no increased demand,thats why your face goes red,swells when upside down.

[@Pavan-_]

🙋

[@judgeady2391]

Well, I certainly am ignorant right now.

[@alanw2687]

I run from the police. No wonder I am so smart

[@alanw2687]

@Intelektshual day no

[@mohammadal-kamsha4020]

No wonder there is no dislikes 👍👍🖒🖒

[@quit91111]

You sure

[@did_i_ask_btchDO_i_look_i_care]

I did weight-lifting after this😁

[@Mviews-be8gv]

I am watching this because I wanna Stop Smoking weed and cocaine

[@sanketvaria9734]

non-aerobic/anabolic exercise also has these effects, just relatively less. Don't missinform.

[@scarred10]

theres no such thing as anabolic training,i presume you mean strength training and anaerobic training and yes it has some of the same effects but the research has been largley done on aerobic training so thats what is recommended.

[@yuisan5128]

I searched this after watch Baki training

[@user-mv1kv2fx6n]

You saw the endorphins?

[@yuisan5128]

@@user-mv1kv2fx6n yea H

[@randomdelirious8770]

I run in cs:go Does that count as aerobic exercise?

[@lawliet2263]

Yes

[@xalian17]

Weightlifting doesn’t increase blood flow to brain? Lololol

[@gm7304]

TTFN Witchboard

[@gm7304]

My hippocampus is a smokin raisin 🧠😃

[@ahmadtheaviationlover1937]

This is way too much information

[@MrSnazzy682]

I know right. Don’t you hate these Ai generated voices too