Electron transport chain and ATP synthesis

This lecture explains about the mechanism behind electron transport chain and ATP synthesis with the help of oxidative phosphorylation. Components of electron transport chain is also explained in this lecture including the protein complex i to V and ATPase. This lecture will help you to understand the chemiosmotic theory and mechanism of action of the ATPase pump to drive the proton motive force that helps in ATP synthesis in mitochondria as a result of aerobic cellular respiration.
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Thank you for watching the biochemistry lecture video on electron transport chain and ATP synthesis also known as electron transport system.

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@Bennett Royal what it has to do with this video

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Sir this is very helpful thank you I'm a b pharm student & this helped in my biochemistry exam 🔥🔥👌

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Thank you Dr. Bhattacharjee for this wonderful video. This video is really an unparalleled one.

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Sir your teaching style is very nice. I'm a Hindi medium student so I face problem to understand any other English medium video but I can understand your video and your English conversation because you are speak English very clear. Thanks alot sir for your help full videos.

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+THE PARTY BLOOPERS it's nice to hear that

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I learned a basic version of this over 35 years ago...unable to even grasp from book...thank you for these patient step by step lessons..Gratitude!

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Ur method of teaching is vry nice sir....

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You are a too good teacher sir Thank you for sharing ur knowledge with us. Thanks from Kerala

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[@beenaasokan8569]

sir my name is sijo. i am a bsc botany and biotechnology student in kerala. we have a metabolism paper. so it helped me a lot. so thank you so much for such good things.

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+beena. r glad to hear that. Please subscribe and share

[@tejasgohil9387]

What about complex II? Still many doubts. At 9:06, you said that "Complex I translocates two protons to the intermembrane space per NADH oxidized. So for a single NADH four protons will be pumped into the intermembrane space". How this is possible?

[@abineshanbazhagan6703]

The second complex doesn't pass through with First complex, and thus both are connected with Q(Ubiquinone) which by reduction(QH2) acts as lipid soluble and so can pass through the inner hydrophobic membrane,and they receive enzymes from both complexes such as NADH2 from first complex and FADH2 from second, using an sucking enzyme called Succinate Dehydrogenase,but since these are initial stages where there is no role in energisation in complex 1(due to bypass), they don't produce much of ATP. Source- lumen learning site.

[@rtrt-tw3ob]

tomorrow is my exam sir and your vedio are very effective for me..thanku so much sir

[@anjalishalajan7718]

This class is incomplete. No information about complex 2.

[@Torque_turn]

U r so helpful sir 💝

[@m_mahi05]

very nice sir.....I liked u r teaching method......

[@anuroy5889]

Hi Sir how many protons are required to form one ATP molecule in Mitochondria and thylokoid because I bit confused that 2,3 or 4 please reply me. Thank you Sir

[@mayapatidar3543]

I liked it sir....i was in desperate need of it to make easy 🌷🌷

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You're welcome

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Am a medical student I use to follow your chemotherapy lesson s ..tq for your valuable vedios.😊

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Glad you liked my lectures

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@@shomusbiologyofficial am happy to see your reply...it's not just glad .your vedios are worth.very simple method u explained everything... please at request if possible do mechanism of action about GI drugs.tq

[@alirazakisana352]

its too good lecture...sir

[@suro-mallar8031]

As you said, complex I translocates 2 H+ to the intermembrane space then how is 4 H+ pumped out? Please clarify

[@atulmishra6184]

I too have this doubt.. If u have got the answer then please reply?

[@sagarh7181]

Same

[@siddheshpathak9181]

When 1 nadph is oxidized , 2H+ proton is translocated , so when 2 nadph is oxidized (that's where he was wrong) , 4 H+ is translocated

[@AtulYadav-dv2tg]

This lecture is very good sir

[@vikaspawar7795]

you are great teacher Sir

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really helpful thank u so much sir

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Thank You Dada 🙏 You made my MBBS journey easier. Whenever I stuck in any topic you were always there with a video 😊💕

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Thank you sir.... Your videos always helped me in my whole journey....

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sir u tell so nicely ,,,,Tq very much

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You literally saved my life!! Best teacher ever ♥️😌

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really..he is a saviour

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Bt luckily exams got cancel 🤪🤭

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@@nishitachauhan8700 but not ours

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[@koyel6069]

can you give video related to sodium potassium pump problems? it will be so helpful. i have problem in solving those type of questions.

[@chandnisingh8707]

Thank you sir 🇮🇳🇮🇳

[@aasawarikhairnar8097]

Isn't it two protons pumped per electron for complex1?

[@user-ww8tu8te3g]

Thank you so much sir

[@barsha_bbs]

Sir i want to knw why through complex i and complex iii ,4H+ ions go out bt 2H+ in case of complex iv? Plz clear my query.

[@vijaymehar1457]

sir what is different between a primary and secondary metabolism

[@umerfarooq-ww5ms]

Well explained sir.

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Thank you sir.... Your videos really help us a lot

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You're welcome

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Thank u sir u are insane

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For what?

[@omgkeralian7404]

for it teaching skills

[@kajalseth7964]

Thank you very much for this video. It really help me a lot!

[@pratikshanadgir1239]

does electron transport chain in eukaryotes and prokaryotes same?

[@kashmirfoodaddiction943]

Thank u a million times🔥🔥

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You're welcome

[@apekshasingh9459]

thanks it helps a lot to understand

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+APEKSHA SINGH you're welcome. Glad to hear that you are getting benefit from the videos

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Thank u so much sir😊😊😊😊

[@hareeshtulasiayyangar8106]

nice video thank u. cute.

[@vijayvelamala413]

I cont understand sir please once again prepare for electron transport system plz.....sir

[@Anlykabiofficial]

Expecting more microbiology and biochemistry portion

[@sbbiswas4]

Very helpful video sir.

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+Soumyajit Biswas thank you.

[@chauhan_61]

Well explained sir Thanks.

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thank u sir you are the best lecturer

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sir thanks

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An excellent lecture. Sir

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your videos are sooo worth watching ,i have been following your videos ...and yes you are cute

[@omkardixit7320]

9:10 How are 4H+ transported inside When i NADH gives just 2H+?

[@salehakhan7300]

plz sir made a lecture on variation and genetics..like gene alleles and gene pool

[@hasdb8215]

thank you for clear explanation

[@shomusbiologyofficial]

You're welcome

[@papiadas7075]

sir cant understand the proton pumping part in ETS ....when NADH is oxidized why 4 protons are pumped why not 2 ?????

[@kingfate4]

this much helpful than i thought

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[@rupalichakraborty4814]

Thanks sir

[@barshasharma582]

I like u and ur video

[@axedhead123]

conversion of succinate to fumarate isnt in the matrix but in the inner membrane.

[@farzananazir6324]

Sir please with vitamins and minerals discuss their uses also plzzzz within 1 day give the video on these

[@sagarbehera7462]

Sir please explain about Q cycle

[@kimjones5429]

In 11:32 where from that in organic phosphorus come from?? Cytoplasm or mitochondrial matrix plz answer sir and if cytoplasm, then how it come in matrix of mitochondria??

[@oneplateidli]

It comes from cytosol via phosphate carrier to mitochondria

[@rscreativevideo5417]

Always u r the best

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Thank you. Glad you liked my lectures

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@@shomusbiologyofficial Tq god of biology

[@jemimahmaria3507]

Thank you sir😊😊...

[@shomusbiologyofficial]

You're welcome

[@jyotivasantraofulpagare6176]

Complex 1 pump 2 protons or 4 protons into inter membrane space? Please tell.....

[@huzaifnoor873]

Can anyone explain please...how four protons are released from complex1 per nadh oxidised....and how 2 protons are released from complex4...

[@Kris_misra]

0:40 o sir now I got it thank u

[@prashantkumarparmanu]

sir , that particular incomplete diagram need to be replaced by detailed one .

[@lailamajnu6925]

Father of biochemistry

[@poonamkoirala4466]

Sir i have a doubt relatd to energy calculation, somewhere total ATP production is 38 whereas somewhere it is 32 ATPs as 1NADH=2.5 ATP and 1FADH2=1.5 ATP Which one is correct sir?

[@shomusbiologyofficial]

Both are correct. Depends on how many atp u consider per nadh and fadh2

[@poonamkoirala4466]

@@shomusbiologyofficial ok thnku sir 🙏😊

[@Dr.Synthesis]

Sir biostatistics ke lectures daliye

[@Msd50431]

Very nice

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You're welcome

[@souryamishra3410]

sir which book do you follow?

[@deblinamandal4555]

Sir , please upload the inhibitors of oxidative phosphorylation

[@KamranKhan-ew2yd]

Sir you said that in complex 3...4 protons are pumped per 2 electrons....??? Isn't it 4 protons per 4 electrons???

[@a29j]

Nope it is 4 per 2 electrons

[@shubhamg23]

Sir,Plz post all the Videos of this series as soon as possible

[@shomusbiologyofficial]

+Shubham Gupta I will be publishing soon.

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Shomu's Biology Thnx😃 for the response

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I'm missing my teacher sir Mohsin I can't find a teacher like him I wish he could create a KZbin channel for biology lectures. I'm 100% sure then no one prefer another teacher he is the best teacher I ever met ;(

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Thnkxx buddy

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Exam is coming..this video helps me a lot ... thank you so much 😊

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nice

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Handsome teacher i have ever seen

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Thank you

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So nyc

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You're welcome

[@kunal_9981]

what about FADH2

[@janvizala1863]

Sir as we know ADP convert in ATP but ADP+ pi kaha se form hota he mtlb ADP cell me pahele se present hota he ya koi cytochrome complex me ???

[@shomusbiologyofficial]

Adp is always there in cell after the use of energy fro. Atp hydrolysis

[@janvizala1863]

Thank you so much sir

[@goldenassassin7995]

I think you should better draw a 100% correct picture of oxidative phosphorylation so we can understand. I m searching the internet 2 days now and i cannot find a correct picture with the correct numbers

[@arjunsr1338]

Can you do a vedio about Drugs for peptic ulcers. If possible all pharmac drugs about GIT.Tq.😊 Your teaching method is very good and easy to understand ..if possible please do it it soon its a request.tq.

[@neetuprajapati381]

Love you

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You're welcome

[@ankitarani6390]

sir please explain complex || , why complex || do not pump any proton ?

[@studywithroma]

Need more details

[@shubhalakshmiswain3328]

Sir why 4 protons are pumped out from the matrix

[@parinita_borgohain]

9.02..It translocate 2 proton per NADH...so 4 protons for a single NADH...samjha nahi sir

[@azharrahmanansari7977]

Helpful

[@shomusbiologyofficial]

You're welcome

[@nabinbhattarai8714]

Write how ATP is synthesis ...so can you show this answer in chart in short form for the exam point of view

[@chakhubangyang6356]

What about complex 2 ?

[@anieshwarnshingri4860]

can you please make a separate video on "BIOLOGICAL REDOX COUPLERS"

[@shomusbiologyofficial]

Okay

[@vivekaanand5917]

👍🏻👍🏻👍🏻👍🏻👍🏻

[@kedargokhale7976]

2.5 ATP? How can a molecule be in fraction? Or is it some kind of ratio, say, that of NADH consumed and ATP generated?

[@shomusbiologyofficial]

+Kedar Gokhale it's a ratio

[@axedhead123]

it is a ratio of ATP per NADH.

[@kanchanshah3521]

Sir ,plz upload lectures on biollogic oxidation

[@kanchanshah3521]

Also malate aspartate shuttle Glycerol phosphate shuttle

[@arnabghosh3896]

make video on Enzyme

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+Arnab Ghosh video lectures on enzyme is made. It will be uploaded soon.

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bhagavan

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[@pragyarairai5407]

Bhagwan 😩😩ho yar ap tqqq ...bs etna bta dijiye that what about succinate dehydronase complex 2nd

[@shomusbiologyofficial]

That's a part of tca cycle enzyme list

[@pragyarairai5407]

Shomu's Biology so why dont u include that also bcoz they are also mentioned in the new diagram of ETC given in ncert this year plz..

[@jeneybasene5855]

Sir is topic par hindi video nhi h kya