This video describes how enhancer elements can regulate transcription from a particular promoter of a gene. Enhancers | Transcriptional regulation by Enhancers | Enhancer promoter loop
Пікірлер: 58
@ChristianGriffioen3 жыл бұрын
Where can I find your more detailed videos about enhancers?
@mgold9999 Жыл бұрын
At 2.30 the green to the right should probably not be upstream but downstream enhancer right?
@stephank917217 күн бұрын
yes, it should be a downstream promoter element (DPE)
@MarvinMonroe2 жыл бұрын
I just learned that my father's cousin (my first cousin, once removed) was instrumental in discovering Enhancers back in the early 80s at Harvard. Julian Banerji, I'm so proud to be related to him. He and his two sisters and his wife and their husbands are all wonderful humans Edit: and Arpan, if you are wondering why I, a white guy in America am related to a Banerji it's because Julian's mother met and married a man in India back in the 1940s. Not sure if she was traveling in India for a summer and met him then or what the story is. Julian's mother and my father's mother were sisters. So my father has 3 first cousins who are half Bengali and I have 7 second cousins who are 1/4 Bengali Im in the middle of reading the account of the discovery, I'll try and link the article here soon
@animatedbiologywitharpan2 жыл бұрын
I am also a bengali
@MarvinMonroe2 жыл бұрын
@@animatedbiologywitharpan that's cool! I love every Bengali I've ever met. Julian's father, my Great Uncle Sid was the nicest person ever
@MarvinMonroe2 жыл бұрын
@@animatedbiologywitharpan I can't post the link but if you'd like to read about the discovery you can search "Julian Banerji enhancer" and you'll find a post that says "happy 40th birthday Enhancer" That post contains the original 1983 paper and a new paper written by the lab director who recruited the team and he tells the whole story. I found it interesting
@MercyMburuNyakio4 жыл бұрын
Literally what I was looking for. The difference between enhancers and promoters really confuses me!
@animatedbiologywitharpan4 жыл бұрын
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@MercyMburuNyakio4 жыл бұрын
@@animatedbiologywitharpan Okay! Done!
@bili4591 Жыл бұрын
I need a video who explain me the mechanism of how a unique stimulus allow more than only one gene to be expressed I am confused.
@animatedbiologywitharpan Жыл бұрын
Thanks a lot for this interesting suggestion. I will try to make one video on that
@bili4591 Жыл бұрын
@@animatedbiologywitharpan ok i will wait, thanks
@jeancorriveau86868 ай бұрын
This video makes me understand better enhancers and transcription factors.
@animatedbiologywitharpan8 ай бұрын
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
@nadeemnaniwala1643 жыл бұрын
Brother i am waiting for your another video on enhancer
@animatedbiologywitharpan3 жыл бұрын
It would be uploaded soon
@alejandraacevedo-muniz62553 жыл бұрын
when an enhancer is bound, it stimulates the transcription of a specific gene? or more genes?
@animatedbiologywitharpan3 жыл бұрын
Very nice question ...actually 1 enhancer can influence multiple Gene's and it all depends how enhancer interacts with promoter in 3d
@animatedbiologywitharpan3 жыл бұрын
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@joanne76994 жыл бұрын
Hello, could I ask if promoter is considered a regulatory element? Some sources do not consider as regulatory element. Thank you
@animatedbiologywitharpan4 жыл бұрын
It is a regulatory element
@joanne76994 жыл бұрын
@@animatedbiologywitharpan thank you for replying! Could I also ask but core promoter element itself Is not a regulatory element right?
@adelaide43563 жыл бұрын
@@joanne7699 no the core promoter is not a regulatory element. Regulatory elements include promoter proximal elements (PPEs) such as the GC box and CCAAT box (upstream of the TSS by ~50-200 bp), and enhancers and silencers. Hope that helps!
@joanne76993 жыл бұрын
@@adelaide4356 thank u
@alphegedinsijohnmojiun29614 жыл бұрын
This could be a subtle subtopic to explain epigenetics since it involves the regulation of gene expression.
@animatedbiologywitharpan4 жыл бұрын
Ya
@rahulrai31606 жыл бұрын
good work bro ..best way to elobrate concept ....thanks
@animatedbiologywitharpan6 жыл бұрын
thanks glad that it helped ...share among friends and help them as well
@ramchandrasuthar28486 жыл бұрын
Very nice analysis sir
@matthiasturcar73293 жыл бұрын
Great video that helped me understand Enhancers. Keep it up!
@animatedbiologywitharpan3 жыл бұрын
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@Brainwise8893 жыл бұрын
Thank you
@animatedbiologywitharpan3 жыл бұрын
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@nicolealoeyi18424 жыл бұрын
approximately how long is an enhancer in base pairs?
@animatedbiologywitharpan4 жыл бұрын
From few hundred basepairs to few KB
@animatedbiologywitharpan4 жыл бұрын
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@PriyaThakur__.__4 жыл бұрын
200bp but can show its effect 1000bp upstream or downstream.
@shrutikasansaria84994 жыл бұрын
So nicely explained Thank u
@animatedbiologywitharpan4 жыл бұрын
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@animatedbiologywitharpan4 жыл бұрын
Subscribe to my other channel kzbin.info/door/4IpyopsGWSjaPACNTZLuqg
@sali3593 жыл бұрын
inaccurate and please buy a new mic
@tonowhereofficial17 күн бұрын
Why is it inaccurate? Please, explain.
@MegaYumna5 жыл бұрын
Pictures in the video are blurry, not clear
@animatedbiologywitharpan5 жыл бұрын
Please increase the quality settings for better graphics