Explanation of the Nuclear Overhauser Effect (NOE) in NMR Spectroscopy

[@eocervan]

Literally the first minute of this video cleared up an hour of confusion omg

[@mahsaababaie9278]

Made 10 years ago, the best video on Noe effect.

[@winterspell9846]

Though I still cannot understand this concept fully, you explain much better than my professor. Thank you very much.

[@noneofyourbusiness3288]

You Sir are a lifesaver. This is the first explanation of the NOE where I actually understood what that thing even is.

[@yanfusheng2171]

Your Post is enlightening and I can understand much more than going through reading.

[@chemtubeuk]

Yan Fusheng Thanks. Glad it helped

[@qvanerp4449]

More clear than two of my Master lectures 👍

[@esikakolaric6856]

This is an extraordinary explanation. Thank you so much, Sir.

[@linuslin2718]

gotta say you explain it a lot more clear than my lecturer

[@erickpatino9221]

Thank you Sir! I was not able to follow the topic in the books but you have made it clear to me

[@niamhmckenna2]

So glad I found this video, it's a really great explanation of nOe, thanks for making it :).

[@linklm780]

Extremely helpful for understanding NOE effect. Really appreciate it.

[@Noesgaard1]

Good explanation, really highlights the key points and how to view the effect. Do you by any chance have videoes on the other effects present in Dynamic Nuclear Polarization, such as the sloid effect, cross effect or Thermal mixing? Would love to see an explanation for those

[@trapgaming1394]

Have a test about this in a few days, this helped a lot!

[@strydomobile]

Thank you very very much sir! Made much more sense than my current notes. Keep us these videos!

[@rohitkhurana7085]

Could not follow it up today in my class. But you explained it really well. Thankyou!

[@ownitup237]

Saving me before my spectroscopy exam! Great explanations

[@Alssndraa]

Your explanation made everything so clear, thank you!

[@shankhadey9669]

This video is highly recommended ..very helpful sir

[@Imagon100]

dangerously good explanation

[@ppppppporing]

This is great. very clear and the explanations on the side are so helpful. Thank you!

[@jahnusatya5197]

Thank you for explaining...i understood the mechanism after listening to your class

[@robertad464]

Thank you very much for this video! I finally got the idea of what is NOE.

[@Appelouz]

A very clear illustration. Thank you!

[@BikashRanjanSahooOSAKA-Japan]

Dear Sir, Thank you very much for such a nice explanation. I do not understand why small molecules render double quantum transition and proteins do zero quantum transition. I am using NMR for protein. I will be highly obliged, if you will make me understand why small molecules show double and big molecules show zero quantum NOE. Thanking You Sincerely Bikash

[@izz314]

Great job done explaining NOE here!

[@sajanipihilikumbura548]

best exxplanation thank u

[@pangulurisaiprasannakumar9695]

You had done a scintillating job! Thanks for this one! God Bless

[@RK68978]

Thank you so much for this! My lecturer did such a poor job of explaining it I was so lost!

[@moromann1]

This makes so much more sense now! Thanks for explaining :)

[@felixromer4335]

realy good explanation thanks

[@togahead]

You are amazing. Thanks for this incredibly insightful video.

[@rahuldwivedi8212]

so fulfilling explanation....thanks for making

[@farwafarwa533]

i am student of mphil chemistry .Thanks this is very helpful for me.please give another lecture on selective polarization transfer

[@karthiksekar189]

Nicely explained Could you please explain abt the double irradiation of source signal Also how to calculate the percentage of noe signal

[@MrMiki434]

Thank you very helpful

[@golinelli1]

Nice and clear explanation! Thank you

[@karthiksekar189]

Pls provide some examples. In my noe spec I am observing peak at negative phase. What is it for

[@junbohou7968]

why I go to the link you post, I can't find the things like you show in the sreenshots

[@Felixkeeg]

This was exactly what I needed

[@spammemama]

Excellent explanation. Subscribed

[@safiullahmajid2885]

Thanks sir ......it was awesome explaination.

[@abhilashghanwat]

Awsome Video..Please KeepThe Good Work. Post More Videos on Analysis. Yhank You.

[@hamitouchehocine6960]

please What is the condition of existence of nuclear overhauser effect between two given spins? And how does it evolve?

[@ashensaranguhewa]

So helpful! Thanks!

[@gammaray0wn]

I just finished watching your videos on COSY, TOCSY, NOESY and this and they are absolutely brilliant. One question on this video: you said that W2 (double quantum transition) is disallowed by quantum mechanics - I thought if something is disallowed by a fundamental law of physics then it's pretty watertight! What do you mean when you say it's disallowed?

[@nichelleuhura6040]

+gammaray0wn Disallowed (usually called forbidden) usually means the probability of it happening is very long, but not entirely impossible.

[@santoshlamichhane1804]

Is this NOE effect responsible for saturation of water signals in PRESAT experiments such as NOESY1D ??? What is the difference ?

[@tooncornette8233]

The 2 hydrogen atoms are chemically/magnetically nonequivalent I suppose?

[@evilyvzzz]

Thank you for your excellent explanation of the NOE effect! Your epistemeo.com domain name is not active anymore, do you have a new one?

[@MadhuryaKakati]

Does this mean that when relaxation of the interesting nuclei happens after saturation, it will happen to the new and different configuration instead of the thermal configuration? As far as I understand only this can change the intensity

[@soheepark7276]

Thank you so much! It was the nice explanation :)

[@indravanzundert3327]

Thank you very much, this was very helpfull!

[@pomuschka]

I like the way you explained it! Thank you so much!

[@yazadtafti3224]

this is a fucking great video!

[@reginatan9054]

thank you so much Sir!

[@williamcronk3385]

Well done, thank you.

[@gero3973]

So helpful, thank you!

[@ahmedalfahad3866]

Thanks very useful

[@naay495]

Thank you!

[@juanfelipeavellanedatamayo6229]

I would enjoy more this video, if my english were some better :'( ... thanks for making it!

[@allthingsafrika]

I am still confused by something. When people mention population difference, they talk about many spins of the source going to the up state and then going back to the down state. I thought that a proton only has one nuclei and therefore one spin so how can there be a population of spin?

[@juanfelipeavellanedatamayo6229]

Remember that you are influencing your nuclei under a magnetic field, what polarizes his magnetic momenta at two posible values, +1/2 and -1/2, each one with different energy. Then, you have a portion of that nuclei in each state of energy, and that population have to favor the transitions, allowing the magnetic resonance when you apply the radiofrequency... sorry for my bad english :/

[@juanfelipeavellanedatamayo6229]

You're right, I just went to the molecule, and even to a portion of sample, directly.

[@FraeschD]

This saved my bacon, thanks! :D

[@rajatrodney6327]

Finesse!

[@mertdinc5459]

ah fuck chemistry master degree

[@gogoi8091]

Hard to understand british accent

[@NephilaClavata]

Thank you for making this channel; it's extremely helpful!

[@user-co6py5ng8l]

So helpful thanks