Inflammation: impact on aging and disease risk, & how to identify & prevent it (AMA 59 sneak peek)

[@chazwyman]

skip first 5:20 mins if you want to know about inflammation.

[@annettesoss2114]

Thanks

[@nickflynn621]

Vote for Pedro!

[@EvaiAten]

I am surprised how this video ended without fulfilling what was promised in the title of the video.

[@elizabethmcgregor4062]

I havent seen the end yet...but what you said is usually the case

[@BorneoAgent]

The title is for the full episode. This is a sneak peak of the full episode, so just a snippet. Full episode covers it.

[@nashscan]

@@BorneoAgentwhere is the full one?

[@ananavarrete7218]

Yes never listened the preventative part 😢

[@lynnerousseau9676]

I think these are TEASERS to get you to 💰/Subscribe to “The Drive”… if you 💰/Subscribe then you get access to full episodes of AMA {Ask Me Anything}☹️😖🫣

[@boomgag]

I have chronic inflammation from an auto-immune condition and I absolutely cannot live without the Protein inhibitor-like drugs mentioned in the video. If you find the right one that blocks a certain channel (in my case interleukin-17), it can remove inflammation almost entirely.

[@lannbak3618]

Nice, now I know Peter does have a sense of humor!

[@peggyon1]

I'm an RN and one major reason I would never work in an operating room is that the surgeon's determine which 'music' will be listened to while the rest of the staff have no voice. Sometimes the 'music' is too loud, too Metal, too loud Rock, etc. Also, I don't think it is responsible to take one's eyes off the patient to look at clips of your favorite show. The focus should be on the patient and not the surgeon. I wouldn't advertise what really goes on in operating rooms.

[@peggyon1]

@@nancyhonea1935 You are clearly not in the medical field.

[@destinyzertuche9367]

😅

[@KevinCapolino]

You won’t be missed, you’re not needed in the ORs, but thank you for announcing you won’t be trying to join.

[@Siticmon]

as a 30yo guy from europe i have zero clue what napolean dynamite is but i enjoyed that segment greatly, thank you

[@radezzientertainment501]

Classic comedy movie

[@nicholasbeck2649]

It's a movie about a few weird misfits in highschool growing up in some podunk town in the middle of Idaho. It's hilarious because it's such an accurate representation of what it's like growing up in a middle-of-America small town.

[@marciamakoviecki3295]

idaho is not middle of America, fyi​@@nicholasbeck2649

[@HkFinn83]

As a 40yo guy from Europe I can tell you…it’s a movie.

[@gloriareszler4196]

Me too! No idea what they are talking about. Better co.munication would be to explain!!👏

[@saurabhav4202]

It's like 2 scientists talking in an airplane and I'm just stuck in the middle. You guys could have simplified the discussion just a little bit for us mortals to understand.

[@agontop1]

You’re right, has nothing to do with mortals tho. He is no smarter than you or I except in his trade. I wonder who is audience is he’s trying to cater to.

[@keyman6385]

A legitimate trigger of inflammation, typically in response to an injury or say, exposure to toxin, which if prolonged, could lead to complications, then you have to deal with whatever is triggering the otherwise symptomatic inflammation - our bodies natural response to injury, which (in part) alerts the immune system to check out the nature of it and react accordingly. Ideally in a measured response that helps slow down the eventual progression to a more severe condition, until you might recover from the injury or else remove the source of toxin. Otherwise, prolonged inflammation, in the case of injury with prolonged recovery might develop sepsis, and the toxic exposure, if sustained, could result in a mutagenic reaction that manifests as cancer etc. Again, inflammation is a symptom/reaction to whatever presumed injury or condition gave rise to it. It's like a baby crying in response to injury. Suppressing the inflammation/baby from crying doesn't do anything in relation to the injury. Now, if it's an 'overreaction' of 'runaway inflammation' that might result in death, then sure - a forced reduction of inflammation would be a good means to prevent otherwise unnecessary death due to overreaction to it - ideally where you clear out the trigger/cause, reducing the trigger for an inflammatory response. A classic example would be food allergy in response to something that doesn't inflict an injury as such, other than the anaphylactic shock which, in and of itself, can kill you. In this case, an Epipen is used, to counteract the inflammation until additional treatment, if required, can be administered.

[@starstern1077]

Oh wow. He has a sense of humor! Love to know this.

[@stillholding4975]

Dude, you're clearly enjoying yourself here. I know I feel cool when I prattle on about my knowledge of construction and engineering. But when I'm trying to deliver a clear point to a client or employee, I try to simplify the verbiage and get to the GD point. You should try it.

[@agontop1]

Completely agree. You’re channel is a general audience KZbin channel, using medical jargon which makes no sense to the everyday person, loses my sub. That and everything being a paywall!

[@PeakPerformanceHacks1]

I love listening to Dr Attia.

[@radiant2012]

This is the typical word salad I get from my cardiologist.. inflammation is what the subject is. There is a drug out there that (IN THE PAST 6 MO) was approved by the FDA specifically for inflammation in patients with active Cardiovascular Disease. My cardiologist will not RX for me/ he rather put me back on the table. It is clear there are people out there who do not want to stop it at the source and practice proactive health care. Sad.

[@Jeph629]

SO much talk. "The Anti-Inflammation Zone" by Barry Sears (2005, Harper-Collins) is still the best and thorough discussion of inflammation and diet out there. Also, it contains no irrelevant reference to the moronic, pop culture motion picture mentioned here, though fans will be excited/beside themselves to know it was written the same year the movie was released.

[@keyman6385]

It's good from the sense of removing from the diet whatever promotes and leads to inflammation vs. trying to suppress the inflammation itself. It's why AIP diet works vs. autoimmune suppressors that just treat the symptom, which compromises our immune function/response which defends the body against all the other triggers we cannot simply eliminate by diet.

[@Cupidduck-465]

Does LDN help with inflammation?

[@epicentering]

Inflammation is an underappreciated component of depression. ❤

[@JDevlin90]

Most inflammation can be fixed with diet. Take out inflammatory foods and food sensitivities by going to the allergy doctor.

[@C8zzzD]

Inflammation is a resource strain, so i would lean towards that, but haven't found any research on it nor am I an expert.

[@epicentering]

@@JDevlin90 I agree. I also wonder if an individual's background viral load, and perhaps early life trauma could contribute.

[@epicentering]

@@C8zzzD good point.

[@nancyhonea1935]

I have heard that an increased cortisol load can be caused childhood related traumas. So, yes, I would agree that the inflammatory process is well established in these individuals before some of them even reach their pubescent years.

[@Michael_Komansky2679]

Napoleon Dynamite. Essential viewing for medical practitioners 😊

[@lukenukem1207]

Inflammation is why Uncle Rico can no longer throw a pigskin over dem mountains

[@GreenLit3]

I bet I could throw this here football over that mountain. Crazy uncles are the THE BEST

[@kman777FW]

I might have to revisit Napoleon Dynamite

[@jugeebean]

Vote for Pedro

[@VeganStrong]

funny this popped up. i just started omega 3 epa about a week ago to reduce inflammation, and i also hear magnesium glycinate helps

[@reforesters]

But, the medical establishment identifies an Hba1c of 5.7 as prediabetic, no matter the fasting glucose level. Any idea why that's the case? Also, Hba1c increases with age. Any idea why?

[@ownerdirector]

How much dairy is considered a moderate amount?

[@vs-yy5cx]

i liked the first 4 mins of nap dyn, but it was a little weird that they didn't even crack a smile thru it!

[@natew4489]

I am noting there wasn’t discussion of icing, cold therapy for injury or the cold plunge stuff.

[@harveyjones1]

I think Peter should do a podcast about crystals

[@brian3185]

The opening bit about Napoleon Dynamite was hilarious 😂. The interviewer is fine btw. Thank you for all your work.

[@philiproesel7885]

Peter, thank you for all of your work. Maybe someone will see and reach out. If I take a round of dexamethasone, joint pain is reduced 90%. Resting hr will drop from low 40’s to high 30’s. Otherwise, I’m one of the healthiest 65 yr olds out there. I am on a very restricted diet.

[@bwspringer217]

The Napoleon intro was too funny… one my best friends from pharmacy school was from Preston, ID where the movie was filmed. Many of our late night study sessions ended with some quotes from the movie. He knew many of the local characters who showed up in the film. He was probably the smartest student in our class but just funny and unassuming. Peter thanks for the info on the podcasts. I get more from them than most CE classes. I’ll have to pay you with change.

[@Krunch2020]

Do they discuss specialized pro resolving mediators?

[@stevespringer8385]

Does the chronic inflammatory disease, eczema, have an adverse effect on metabolic health and aging?

[@tompribyl2884]

I have the same question. I suddenly developed severe eczema at age 50. It did not respond well to any treatment until Dupixent was approved when I was 57. That is a miracle drug. Now 64 and about 90% of my eczema is gone.

[@raymonddowns6064]

Ok so the first 3:30 of this video has revealed to me that I have been living under a rock…

[@Rose-nb6su]

I will go read Barry Sears. Waste of time to listen here for a sales calll. Wish we warned in beginning.

[@aa-xn5hc]

why is it not on the website yet, after days from the YT preview?

[@allyjhughes]

Is this a repost?

[@robynhope219]

Would like to know if the venison jerky you eat is homemade. Is beef jerky ok? I need a lot of protein...thanks!

[@CursedKitten1]

That shot of Peter looking at the guest through the screen gave my psychic damage

[@miaash3870]

You need to explain to the viewers/audience what Napoleon Dynamite is.

[@ShastaTodd]

Google is your friend!

[@kathrynpoppywagner]

When women bloat monthly (or menopausal-aged women are chronically bloated), is this a “qualifying inflammatory response” as defined by this podcast? Even if C reactive protein is not elevated?

[@karenhikesalot]

Napoleon Dynamite is the greatest movie of our lifetime, hands down. It beats out The Goonies

[@BillyBoy66]

Hey Dr. Attia, do you have any plans to comment on the Lean Mass Hyper Responder study done by Feldman and Norwitz? Would love to hear your opinion, as always.

[@Krunch2020]

Ha ha! I doubt it. He believes the LDL hypothesis. You’ll have to look elsewhere for interpretation of the Citizen Science study.

[@samstone32]

Peter, I am a big fan, have the book watched lots of KZbin, but this one was a total waste of time. Consider redoing this KZbin so that the average citizen can understand what you are saying.

[@williampeterson3089]

0705 isn't it meant to be a farce??

[@Pablocajiga3093]

Brilliant, Opening, middle, and ending. !!

[@MaddenScience]

Railing against superfoods yet advising/investing in AG1?

[@rufisdodd4318]

HA good point. Also when he says "There is no evidence..." He needs to clarify is this because there was not highly funded studies, or has there been lots of studies and no advantages have been found. Like in the case of super foods.

[@vladimirbellevueinnovation4835]

Huge Napoleon Dynamite fan.

[@MandalaBunnyhome]

AMA question for Peter Attia- have you ever laughed or are you always in doctor mode

[@robynhope219]

Just finished reading No Time To Die in the NYer. Never heard of you before then...agreed with all you said about aging. You say that with each decade after 30 we lose a meaningful amount of muscle mass and cardo fitness. This certainly happened to me since my chronic fatigue diagnosis...so depressing. I'm already in my 70s, so cant expect a lot of change at this point. Pleased to know i'm doing a lot of things right. I carry heavy bags of groceries in both hands despite my hip surgery that left one of my legs a bit shorter. I am definitely on an anti aging journey. Cheers!

[@annettesoss2114]

70s? Never to late!

[@annettesoss2114]

I might have to watch this movie😊

[@R2RHIker4]

I still have a talking Napoleon Dynamite doll. Push a button, and you get 16 different Napoleon quotes

[@justinklenk]

Brilliant appreciation piece on the genius of Napoleon Dynamite... Fuck all that I clicked on this for. Also, I finally spotted it/pieced it together: Peter Attia is the Jordan Schlansky of wellness science. 👍

[@samanthahammondsrealtor]

1:39 the seriousness that was taking place when talking about napoleon dynamite and inflammation .. I cannot tell if this is a joke or legit 🤣

[@nrjetik1]

I could have made state!

[@JS2k514]

While you are at it, give me advice on hair loss prevention.

[@mbmurphy777]

This had literally no information in it related to the title.

[@frankconte]

What a waste of my time!

[@tomsamek2936]

New levels of sarcasm have been achieved here (first five minutes)

[@lindamagness1167]

Watched a bit of Napoleon Dynamite. What a pathetic ,ordinary movie. What the hell do you think is so remarkable?

[@jugeebean]

First time it's stoopid....but the second time you get it.....and then watching people watch it for the first time while they aren't "getting it," is even more entettaining.

[@intrepidvirgo938]

I’m a napoleon dynamite fan likewise PA! Vote for Pedro!

[@immortalityIMT]

How did Elon Musk's Neuralink brain chip get approval for a human trial or is it a case of do not go there?

[@peggyquinlan2364]

He’s hilarious in a very low key manner.

[@Joy80JJ]

Never was interested in that movie...

[@imaginationland474]

peter being a napoleon dynamite fan is a very unexpected yet welcome attribute of his personality. lmao

[@briand5379]

Napoleon Dynamite is no doubt a good movie, but if I had to listen to the soundtrack every day for at least a month, I'd probably never watch the movie again.

[@ALT-vz3jn]

This was mostly useless.

[@emmaluciaev1938]

True

[@michellem434]

Great movie lol

[@jodie3339]

Eat your ham, Tina!

[@MT1-ee7nf]

Impossible to follow Dr A’s constant acronyms throughout, assuming the audience knows, even if a clinician

[@QuintinHowell]

My respect for Dr PA has just gone up 1000%. Napoleon Dynamite... 😂😂 I just want to say, your mom goes to college

[@hay_w1re645]

If you watch napoleon dynamite once, you’ll hate it. I imagine it’s the same with the soundtrack hahaha.

[@cdtimmin]

One more video from this doc that doesn’t have the solution!!

[@Smitch-hw1bv]

Once again, peter this seems like version 2.0 that you play this little clip and then say spend $20 a month on being a member … I appreciate your hard work, but perhaps five or six dollars would be reasonable since you talk about people not having the money and yet you make this content exclusive… seems ironic…

[@qualqualie1518]

❤

[@brendanwilliamson4590]

Wtf bait and switch!

[@casselskeep]

What is all this napoleon dynamite stuff?!? Hilarious 😂😂😂

[@spnyce4414]

WTF!?!?!! really???

[@peterkizer6163]

"Napoleon dynamite"??? WTF.

[@oceanside66]

Very disappointing content.

[@81aherna]

How you know when you have inflammation is when you feel life shit.

[@josh_wags]

😂

[@mzoesp]

Useless.

[@robertbowen4533]

Pete loss the nice guy doing the interveiw style show iit reflects poorly on you and is somewhat insulting to the viewer. Not saying your pal is not smart. He can make on his own and you will do better by yourself

[@GABAG00L]

Congrats on one of the stupidest comments in this year

[@ghostcat2465]

It's like i'm reading a chatgpt 2.0 generated comment.

[@lotfibouhedjeur]

I so agree with you. I just don't get the interviewer, and he does reflect badly on Peter. I just wanna listen to Peter. He's on point, he knows what he's talking about, and he has that voice. Really, there's no need for that other guy.

[@joebartles3986]

Can you translate into English please?

[@robertbowen4533]

Thank you😊​@@lotfibouhedjeur

[@cuervos69]

Misleading title

[@mzoesp]

Useless.