FDA Approves First Crispr Treatment for Sickle Cell Disease

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Күн бұрын

A gene-editing therapy for sickle cell disease was approved by US regulators, a milestone for the DNA-modifying technology Crispr. Crispr Co-Inventor, 2020 Nobel Prize winner in chemistry, and Innovative Genomics Institute founder Jennifer Doudna joins Caroline Hyde and Ed Ludlow on "Bloomberg Technology."
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Пікірлер: 70

@christopherhumphrey 5 ай бұрын

This is really awesome news. It's great to see people still trying & succeeding in making cures. Not just treatments.

@bootiemacarthur9182 5 ай бұрын

Love Jennifer’s dedication to humanity….so very caring and knowledgeable! I truly believe medicine will be advanced in every area of human life!!

@KumariKumari-fw7nc 5 ай бұрын

DouDNA born for this.I love her... She is so dedicated to her work...

@nohemyrueda4254 5 ай бұрын

Gracias a Dios 🙏🏾encontraron este tratamiento por miles de personas q cargan ese gen en su ADN.

@remildejesus 5 ай бұрын

just wow!

@Dankpuffin 5 ай бұрын

I love science!

@attila7092 5 ай бұрын

People here are shocked by the price tag. It must be remembered that all types of health care is a business before anything else

@ageofdoge 5 ай бұрын

Most new tech starts out expensive and poor quality. The first cell phones cost dollars a minute, worked almost nowhere and had batteries the size of a brick that didn't last very long. Those early high prices pay for mass availability and better quality later.

@ToneyCrimson 3 ай бұрын

Its funny, they use public funding to RND technologies like CRISPR, but somehow private companies gets to make profit by selling it back to the people.

@ahmedahm1 Ай бұрын

Bluebird Bio all the way 🐦

@errinwright 5 ай бұрын

Totally rad

@milanpintar 5 ай бұрын

Can it be used for Huntington's?

@Grant918Tulsa 5 ай бұрын

If you're science department has received any government funding bra. It really belongs to the people.

@Anythingforfreedom 5 ай бұрын

Dumb

@LaxmiShahi-tb8yq 5 ай бұрын

Good news dr yhank you

@korean_crush Ай бұрын

wait this treatment avalible for beta thalassemia trait people?

@nourahmed2318 5 ай бұрын

Where's hiv cure

@jimbojimbo6873 5 ай бұрын

Hopefully not too far away from genetic modification

@indiancitizen3013 5 ай бұрын

When it'll come to other countries?

@AnirbanGhosh-eu5fm 5 ай бұрын

Approved in UK, USA and Bahrain. Pending approval in Saudi Arabia. Vertex has global presence so I am sure this is going to be rolled out in all regions in the next 2 years.

@shinobikyojune1849 5 ай бұрын

@@AnirbanGhosh-eu5fm since everything works with the money agreement if some states authorize all the others authorize it for the moment it is only Canada and the United States

@ivaaization 2 ай бұрын

@@AnirbanGhosh-eu5fmsirve para curar el VIH Es una inyección??

@andreialcaza 5 ай бұрын

Lets gooo !

@sinamirmahmoud7606 5 ай бұрын

love ❤

@Kyedo2022 5 ай бұрын

Does it work with all people??

@financeroyce474 5 ай бұрын

🤣

@joedellinger9437 5 ай бұрын

Can a mother carry a pregnancy after this treatment? Because it works by disabling the malfunctioning adult hemoglobin gene, leaving the good fetal hemoglobin gene to activate as a backup. But the purpose of having two versions of hemoglobin is that the fetal version binds oxygen better than the adult one, allowing the fetus to pull oxygen out of the mother’s blood. If the mother’s blood also has the fetal version, what happens?

@hvqc09 4 ай бұрын

Good question. Yes, a woman would still be able to become pregnant and carry a fetus then deliver a healthy baby. CRISPR edits the mutated hemoglobin gene and tells the body to produce "normal" adult and fetal hemoglobin.

@joedellinger9437 4 ай бұрын

@@hvqc09 Hmm, my understanding was they just break the adult gene… with the result that the fetal hemoglobin gene reactivates. But I could be wrong. Using CRISPR to make controlled substitutions is still experimental I thought.

@user-le8tv3dg9o 5 ай бұрын

Omg good news thank you😂😂😂😂😂😂😂😂😂❤❤❤❤❤❤❤❤❤

@bernob9770 5 ай бұрын

wow

@Jay-nice 5 ай бұрын

@6:13

@user-xk6ps4xo2f 5 ай бұрын

Yeah, does nobody remember the beginning of I am Legend? JD even looks similar to the female Doctor in the beginning of the movie!!!

@spektred 5 ай бұрын

The resemblance is uncanny 🤣 kzbin.info/www/bejne/eGTbiml8m96Sracfeature=shared

@orion9k 5 ай бұрын

LOL tell me more? Why is peoples comments hidden under your comment 😂

@user-xk6ps4xo2f 5 ай бұрын

Why indeed...

@BlanBonco 2 сағат бұрын

Scifi is often cautionary but almost always imaginary and hyperbolic. We probably will die of heatstroke before the Jetsons happens

@kinngrimm 5 ай бұрын

What about the remainder of the population? Do they have a right not to introduce those genes into their genepool? If yes, how would they know with whom not to procreate?

@joedellinger9437 5 ай бұрын

They only modify the cells that make blood. Not the cells that make egg and sperm.

@user-qx1wl2um2k 5 ай бұрын

2.2 million dollars for the treatment.

@U23721 5 ай бұрын

A lifetime of treatment for sickle cell anemia is estimated at 1.4 - 1.8 million. I bet costs will half every few years for this treatment just like all other new technologies as they scale. In 5 years, bet it will be significantly cheaper than a lifetime of treatment and thus insurance will actually save money to cover the treatment.

@bme7491 5 ай бұрын

Not to mention all the pain of the chemotherapy as a prerequisite and the months of being in a hospital bed.

@indiancitizen3013 5 ай бұрын

@@U23721 Absolutely it would be cheaper within few years

@AnirbanGhosh-eu5fm 5 ай бұрын

Actually lifetime cost is between $4-6MM (as per CEO of Vertex) and that’s not even counting the humanistic cost of carrying this deadly disease.

@indiancitizen3013 5 ай бұрын

@@AnirbanGhosh-eu5fm Less than 1% patient can afford it If every pharmaceutical company give this treatment then it would be cheaper soon

@Frank020 5 ай бұрын

2.2 million minus the cost of diverted resources. to explain some poor dude goes into ER but all hands on deck doing a transfusion, dude in ER dies. How many? Let's compare that to the cost of one transfusion a month. Costs aren't getting any cheaper. due to inflation the cost may be higher later. Also, all the pain these poor patients go through, and they may be able to lead a normal life.

@Grant918Tulsa 5 ай бұрын

You would think diabetes would be next on a list.

@Kami84 5 ай бұрын

Most diabetics are type II which is only partly genetic. It isn’t as directly related to genetics as sickle cell disease. Type II diabetes is more of a lifestyle disease having to do with poor diet, obesity, and low activity.

@KumariKumari-fw7nc 5 ай бұрын

What about cancer...

@Kami84 5 ай бұрын

@@KumariKumari-fw7nc it would be perfect for cancer since cancer is caused by DNA mutations that cause abnormally uninhibited cell replication

@ivaaization 2 ай бұрын

Y para curar el VIH???