Fluids and Electrolytes: Calcium Made Easy (Part 2) | Nursing Webinar

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[@iMaGiNaTiOnWpAsSiOn]

If calcium causes excitability, why would less of it (hypo) cause muscle contraction? You’d think if a cell is excited, it would contract??

[@PicmonicVideoNursing]

Hi there! Here is a message from our scholars regarding your question! "Calcium, particularly ionized or “free/unbound” calcium levels, facilitates nerve conduction, muscle contraction, and muscle relaxation (Suneja, 2019). Muscular contraction relies upon myosin-linked regulation sites located on myosin (think a protein acting like a “molecular motor”) and low calcium blocks these sites (Szent-Györgyi, 1975). During muscle contraction, and given sufficient availability of ATP (energy), myosin “motors” bind with another protein called actin (Cooper, 2000). Calcium triggers this action via nerve impulses, with the muscular cell’s sarcoplasmic reticulum releasing stored calcium into the cell’s cytosol. An increase of calcium concentration signals muscular contraction as it binds to two accessory proteins located on actin: tropomyosin and troponin (Cooper, 2000). This process has difficulty occurring if there is an inadequate amount of stored or available calcium, and the muscle cell’s resting potential (electrical charge) increases due to increased neuronal cell permeability (acting upon the muscle cell), leading to increased excitability and tetany (Hall, 2010)."

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[@PicmonicVideoNursing]

Hi Marbella! Thank you for your thorough feedback. We really appreciate you taking the time to let us know your thoughts, we will keep your feedback in mind going forward. We hope you have been enjoying our more recent videos, as we have different presenters now! Happy studying!