Formation of DNA Double Helix

[@semiramisyilmaz3693]

you're doing such a great job! millions of thanks...

[@AKLECTURES]

semiramis yilmaz you're welcome! :)

[@zed1671]

Amazing to see how much you have covered on your channel, and very well explained. You are a god amongst men!

[@移居宜居墨爾本]

Can't mention how useful the content provided. Thank you hundreds and thousands.

[@carlosvasconcelos4463]

You have no idea of how much you're helping me. Please if possible do a lecture about Recombination DNA its just driving me crazy.

[@bitasadeghi7995]

omg I don't know how to thank you enough , I am learning more than I ever learned in my 4 years of uni as bio major

[@MariaM-md6xj]

Thank you and I love you! Finally I can understand biochemistry! ♥

[@jaydeepsharma6914]

I never ever saw such symmetrical and systematic lecture ever !!!

[@kujirakan9537]

12:57 entropy in the surrounding decreases; but heat release after the reaction compensate

[@verasavastano1863]

Dear AK, LET ME LOVE YOU! I’ve got a question: What about deltaH? Is it negative in double stranded dna and positive in single stranded DNA?

[@Sam-ir6iu]

hey AKLectures, try putting your newer videos in a playlist. These videos should be getting more views for your outstanding efforts.

[@AKLECTURES]

Samuel Souto hey sam, will do. but the problem with youtube is that it limits the playlists to 200 videos. my website generally serves the purpose of organizing my content much better.

[@sofiamarazopoulou2334]

This was a very good lecture by combining your previous lectures. Well done !!! And thank you for helping me understanding biochemistry much more in detail ;)

[@junczhang]

thank you for spending time making these videos!

[@carlosvasconcelos4463]

I would suggest for you to compile all your lectures in DVDs and put it for selling :-)

[@sydulchoudhury7444]

Great videos. Quick question: if the DNA bases are non-polar, how are they H-bonding with one another?

[@Mayflower018]

Only N-H or C=O bonds are polar in nitrogenous bases. There are only a few of them and they are bound to relatively huge planar Carbon-Nitrogen rings that are very nonpolar. So overall we can say that nitrogenous bases are nonpolar, especially compared to phosphate ions (if it's charged, it's hydrophilic, polarity isn't really considered in ions) and sugars (yes it is a bulky ring too, but every Carbon is bound to an Oxygen making it more polar. Sugar can dissolve in water and blood, and it has a hard time getting through hydrophobic part of membrane which is why it requires transport. All of this is to say that sugars are polar). Just because a molecule overall is nonpolar, doesn't mean it can't have a few elements that participate in H bonding. The most convincing evidence I can give you is cholesterol. Cholesterol has a single OH at the very end that can hydrogen bond. Does that make cholesterol as a whole polar or hydrophilic? No, because all the bulky nonpolar hydrophobic rings largely outweigh the hydrophilic OH.

[@backstreetfan2887]

@@Mayflower018 Thank you for your explanation

[@rihabmudhafar5924]

Thank you From Iraq ❤❤❤❤❤

[@chenge6580]

good lectures ! Thanks

[@eup2309]

damn good teacher and his course.

[@roymustang1476]

Millions of thanks for your lecture!But I have a question.The entropy of DNA decreases while the entropy of water molecules increases, so how do we know the entropy change of system?

[@abdelkaderabdelkaser9430]

regards, great videos!! you said the bases are non polar molecules, then how can the bases do H-bond? Thank

[@angelicaanonuevo3210]

2 nonpolar molecules with hydrogen bonds around them is acceptable, based on the illustration presented

[@johntindell9591]

Thank you so much.

[@sabikai4404]

i love these videos..i love you too bro thanks.. i am bioinformatics student

[@gotitboom]

how do the separate strands find each other in the solvent??????

[@anthonyman8008]

how do you know this is right? And can I work with you?

[@sagalabdirahman5966]

Thank you Ak lecture You share us great video which helps us structure of DNA althought DNA makes me crazy

[@teeksha1081]

god teacher for me😊😊

[@dradrianjasper1006]

Amazing job!!

[@kuschonink]

I really want to translate these lectures into Chinese version and introduce you back to China. Could you please give me some little advice/ help? DANKE.

[@richardshane2080]

Please don't K don't be discourage you got some of the smartest students here you're a genius but so are we and we're all trying to think really deep don't sigh for exasperation sigh for a relief that people are really into it it just microcosm text nuances don't take it personal I love you you got an awesome thought you're a great teacher I wish I could spend a day with you you're an awesome person

[@hadysaad2157]

Aww

[@NurAlam-jd4yv]

Need lecture for Domain and motifs. BTW thanks a lot for your great job.

[@arunkumars6257]

Thank you!

[@summiyakhan2068]

Plz upload one lectuer on major and minor grooves and their function with simple and full explanation

[@richardshane2080]

My observation AK spin is the only essence of energy that we can create or destroy is this true or not spin the essence of spin

[@littlerascals6529]

Bkat 2d11 stay out of the dumpster hobo

[@peacelover2631]

Bkat 2d11 my observation is that you should take a bath once in awhile so we called that number you never answered that is rude brah Jerry even made cookies for our road trip so you can give us that beat down brah ! Lol what a lifer !

[@sportsport1654]

I am stupid how it's possible that base of DNA forms hydrogen bons when they are hydrophobic

[@johnsantalucia7290]

The bases are NOT hydrophobic. See my comment above on Sept 1, 2020.

[@richardshane2080]

That's beautiful the spontaneity of spontaneous creation by logical sequences created by Elementary particles that exist, why? Why do elementary particles exist theorize it's a trajectory spin phenomena and that's the highest order is the hydrogen spin and that all elements are subsets of the original trajectory spin so you can in Essence harness the trajectory spin one way by dragging the original trajectory spin by creating heavy Elementary particles by combining unharmonic spins it I'm not sure if you can adjust it the other way I haven't thought it out yet

[@littlerascals6529]

Bkat 2d11 stop stinken up the place hoboinator

[@peacelover2631]

Bkat 2d11 you haven’t thought it out yet you haven’t had a thought in your mind in years!

[@richardshane2080]

I disagree with your observation that the universal entropy is toward chaos there's another Miss observation I believe that you may put it take predicate your hypothesis on which is readily substantiated as a theory that works but I believe you're beginning observations are just a little off and may give you Clarity if I were to explain it to you I suggested entropy that you're suggesting or alluded to is one only in our galaxy it probably exist in all galaxies however I don't think I can postulate and say the universe as a whole I may be wrong I apologize for being so rude

[@AKLECTURES]

sigh.

[@littlerascals6529]

Shut up ya government lifer fuck

[@peacelover2631]

Little Rascals ya i think thermo dynamics didn’t work when they towed my dumpster for example gravity took over and at a 45* degree angle caused me to fall off causing severe damage to my anus when forward momentum caused a police officer’s foot to go up there 😩. Hey did you get formula to combat 𝘍𝘶𝘯𝘨𝘶𝘴 behind my testicular sack ? It itches really bad and im still waiting on those test results to cum back hopefully he’s not pregnant again i still owe for the last aborted fetus 👺

[@peacelover2631]

Bkat 2d11 wow you absolutely make no sense why don’t you make it clear in your observation in why you don’t agree with this gentlemen. Please you are blocking people who want to gather intelligence from getting it so please take a bath 🛀

[@vipulshirsat3644]

💛💛💛

[@richardshane2080]

To substantiate that I have been paying attention to your AK lectures you're talking about a hydrogen bond on a sugar phosphate backbone which keeps it electrically (the ATCG base pairs) neutral and allows a hydrogen bond to participate with the other elements called oxygen nitrogen carbon create a geometric function possibly for encoding enzymes to help facilitate in protein synthesis and other cellular work The DNA is hypercoiled by the hydrogen bond with an antiparallel schema is done on purpose to minimize errors we now know that and we know a ATCG correlates to a special electrical bonding you explain it the best of course I have been paying attention I love science I love physics thank you for everything you do don't ever get discouraged by your students the ones that ask the stupidest question are the ones that are seeking an answer sometimes I hope my Forward earlier to JRE was not inappropriate I was just excited to share someone with intellect like you

[@littlerascals6529]

Bkat 2d11 take a bath hoboinator

[@peacelover2631]

Little Rascals you know the average Hobonater takes about two pounds of poop per day multiplied by the gravity of sun pulling on the earth 🌎 and when the moon is blocked by your anus causing a pulsating pressure in your head then you create a massive stinky poop 💩

[@richardshane2080]

I suggest the common observation of the beginning of our reality is slightly incorrect I theorize and postulate something that seems to be readily scalable and does not contradict our physic laws whether Quantum or Newtonian and has a lot to do with trajectory spin at the initial essence of reality that's what I was trying to allude to when I was talking about our lives as metaphysical maybe the rudder in our lives is our thought and Consciousness and it resonates with the universe as a system that obeys thermal dynamics in a cohesive design with other systems called biological species ....

[@littlerascals6529]

Bkat 2d11 I suggest you take a bath

[@peacelover2631]

Little Rascals soap melts in his presence most likely corona came from him .

[@littlerascals6529]

Bkat 2d11 we like your instagram account

[@peacelover2631]

Little Rascals I saw DAT brah that’s the account with the dumpster on it and the pile of poop petrified in the front, i think this one likes fudge pops most likely chocolate ones 😩👺

[@littlerascals6529]

Hey ya government lifer get a real civilian job