Frameshift mutation

[@itzme___sowndharya]

U r the only guy who teach to me any difficult lessons make as easy 👍👍Keep rocking

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@salimaaburabea1458]

I have to say that u teach better than my professors in the university

[@joeymoodley3614]

By far the most well explained lecture on frameshift mutations. Thank you!

[@shomusbiologyofficial]

+Joey Moodley thank you. Glad you liked my lectures and

[@ibrahimcecuaeu1365]

Can it happen by adding more than one base?

[@theeargasmchannel]

this guy saved the day

[@shomusbiologyofficial]

You're welcome

[@julygarces2511]

wow, this guy is above his time. we are now dealing with frame shifting mutation due to covid 19, and this video is 8 years old

[@shomusbiologyofficial]

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[@RaviKumar-bg5xb]

Dad sottti concept dao tumi sera ...bhogoban tomake bhalo rakhuk 😍☺☺☺

[@shomusbiologyofficial]

Thabk you

[@josephinerioki3416]

Your teaching is so simplified. This is great

[@shomusbiologyofficial]

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[@afinamazidah5732]

Thanks for helping my exam prep! Youre the best teacher

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@NanaJuma-w4u]

What a fantastic and simplest way of explanation Kya bhat hai thank u❤

[@shomusbiologyofficial]

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[@karisa7121]

You have a real gift for teaching.

[@shomusbiologyofficial]

Thank you

[@bharathvamshatilak2795]

Sir ur awesome.Iam subscribing ur videos rite now.Whatever may happen plz don't stop.

[@shomusbiologyofficial]

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[@silversky14FM]

Thank u very much. I learned a lot from u and ur videos 💞🙌 Please keep going 🌸

[@lonelygamerzwala4131]

You deserve a 10M support sir nice lecture . How so tough topics you teach in so simplify way? Thanks a lot sir. 🙏

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Stay tuned for more

[@manjuv.pillai7519]

i just wanted to know if there is an example for frame-shift mutation or not, and i found your channel. worth it

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@dosa]

thank you for the explaining frameshift mutation. very helpful!

[@prashantchauhan3852]

Woh...really liked your way of teaching...SUPERB!!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@asmashakir7859]

Now I think alevels is much less complicated for me.I am really very thankful to u

[@shomusbiologyofficial]

You're welcome

[@طيبةيونساحمدحسن]

you are so great dr i dont know how to thank you for this amazing explination , from iraq all respect

[@shomusbiologyofficial]

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[@mariama.sgodhelpme2264]

Great actually , your explanation is perfect , many thanks from Egypt 💖🌷

[@shagunsharma5060]

God of biology,blessed to have you sir🧿

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@VagishShandilya]

The gist of the topic is in the middle of the video. It could have been more brief(healthy suggestion). However, it helped!!

[@shomusbiologyofficial]

Thank you

[@sagnikbanerjee8342]

I got an awesome teacher today. Thank you sir ❤

[@shomusbiologyofficial]

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[@sudipbag1507]

thanks sir..ur English is too simple & good..thanks for help me

[@cindysalinas8608]

thank you soo much !!! keep making videos you're so helpful

[@shomusbiologyofficial]

Thank you very much.

[@biologyteacherghulamyasin2555]

Sir yh Mara WhatsApp no ha please send me ur video 03491672904

[@ankitasaha2861]

Thank you so much Sir, your lessons are so much helpful to me

[@shomusbiologyofficial]

You're welcome

[@Khulood_9]

How can I differentiates between the fixed mutation in insertion and dilation and the farm shift mutation?

[@xyxy2726]

amazing! thank you so much. this video helped me understand the difference between frameshift and point mutation.

[@shomusbiologyofficial]

You're welcome. Glad you like it

[@abhishakespeare2298]

Best explanation Plz add neutral mutation video

[@shomusbiologyofficial]

Thank you

[@TheBlueLagoons]

Isnt a frameshift mutation a change in the reading frame changing the position of the translation stop site? therefore affecting the length of the polypeptide chain?

[@TheBlueLagoons]

resulting in abnormally long or a prematurely truncated protein? please let me know, thanks.

[@halilhadzisadikovic672]

You mixed this with nonsense mutation.

[@ابراهيمالبطوش-ن2ض]

In from Jordan and I understand so much ❤❤❤❤❤❤ thankyou ❤❤❤❤❤❤❤❤❤❤❤

[@shomusbiologyofficial]

You're welcome

[@thomasho6036]

Love ur channel,it helps my MT test a lot. Namaste, Thank u !!!!!

[@shomusbiologyofficial]

You're welcome

[@uzmashaikh1007]

It was so so nice video.. I really saw all your videos..

[@shomusbiologyofficial]

You're welcome

[@Mr.MEHTY5]

I have questions if we add Three nucleotide to our DNA on exons part do we have Frameshift mutation again or not? And why

[@akyir3722]

Sir is thalassemia an example of frame shift mutation??

[@mariamsh2508]

Thank u so so so much your videos are just amazing, you made my life easier while studying mutations

[@shomusbiologyofficial]

+xxoo thank you. Glad you liked my lectures

[@MuhammadYusuf-bi3ly]

Thanks u for this wonderful demonstration sir

[@shomusbiologyofficial]

You're welcome

[@SweetRose-sb5zy]

Nice explanation brother

[@shomusbiologyofficial]

Thank you

[@deefernando4359]

If FRAMESHIFT occurs by adding a Nulceotide, what happens to the STOP CODON at the end???? Surely this mutation would not be viable if the Ribosome cannot complete the sequence without the STOP CODON which would also be reduced to "SHANNON Information"?

[@PRITO_PRITO]

as always... superb....thank u sir ..

[@shomusbiologyofficial]

+PRITIMAYEE BEHERA you're welcome

[@hiraasif7321]

U teach very well 👍 just keep it up

[@shomusbiologyofficial]

Thank you

[@sujataghosh1624]

Thank you for clear my doubt 😊

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@abirraybardhan5483]

A frameshift mutation may produce a) a single amino acid substitution b) multiple of three amino acid substitution c) multiple of six amino acid addition d) all of these Explain with reason plz

[@asmashakir7859]

Answer is b because his is substituted with 3 aminoacids thr ser ser

[@divyavarshney6222]

sir frameshift mutstions are always deleterious ?

[@shomusbiologyofficial]

Insertions can be there too

[@divyavarshney6222]

@@shomusbiologyofficial sir i think deleterious mean by the harmfulness...? then what is the ans ?

[@shifra3203]

In tamilnadu book the part highlighted for frame shift addition mutation is wrong

[@bbulkurcuoglu]

how do we correct a frameshift during insertion of a gene on a plasmid

[@taniabhadra9313]

Thank you so much ! You made it very easy for me❤️

[@shomusbiologyofficial]

You're welcome

[@ibrahimcecuaeu1365]

Can it happen by adding more than one base?

[@zainosman4949]

I"egyptian thank you v. much amazing explaination you are realy helped me to; nderstand it

[@Crisutza1988]

Wow! I’m not even a med student and I understood😜 Last year I discovered multifocal ductal invasive cancer and got through double mastectomy. I also got tested for breast cancer gene mutation and the results were positive for 2 genes: brca2 missense (hererozygous) and nibrin frameshift c.657_661delACAAA (heterozygous). Could you tell me how high is the risk of cancer coming back or development of new tumors in different areas of my body? Thanks a lot!

[@mls564]

thank u so much sir,ur videos helped me lot in understanding the concept. thank u so much sir

[@stephenaguero1493]

Hold on a second before watching! If you're saying CAT is your codon for the RNA strand, that is impossible because RNA does not incorporate Thymine nucleotides. RNA incorporates Uracil nucleotides. If CAT is your DNA template strand 3 to 5', then your RNA codon 5' to 3' should be GUA which does not code for the amino acid His, GUA codes for Valine.

[@mahimagirase9379]

I just want to know.. do CAT code for Valine or Histidine.. Do reply soon..

[@mahimagirase9379]

Because when you taught silent mutation.. CAA & CAT were coded as Valine.. And here in Frameshift mutation.. its histidine..

[@javeriyaqureshi727]

Easy to understand thank-you

[@shomusbiologyofficial]

You're welcome

[@mihir4719]

Phle jo pretune set kii huii h na usko thoda slow kr do... Aapki aavaj se ye bahut jayada h so balance nhi ho rha h volume ka

[@layekdaily3640]

Thank you very much sumon brother

[@shomusbiologyofficial]

You're welcome

[@mariacool1037]

like ur videos alot. keep up the good work

[@jollynass6143]

your a amazing teacher. thank you!

[@shomusbiologyofficial]

+? Thanks

[@lameesalkhier1736]

You are amazing 👏 God bless you 🙌

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@lameesalkhier1736]

@@shomusbiologyofficial you absolutely deserve it,keep going

[@princesspari8427]

in silent mutation and in frameshift mutation similarly sequence is changing so y in frameshift mutation the rest of the sequence would change?y not in silent mutation?

[@snehayadav5123]

Because in silent there is substition not addition and deletion ok Thank you.....

[@bhaskargugulothu7625]

Explain about suppression mutation?

[@dina123-d4o]

Many many thanks sir jee

[@shomusbiologyofficial]

You're welcome

[@musicspinner]

What about notation for fs*

[@mmcmmc2]

Thank you for this explain 🌹🌹

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@biologyteacherghulamyasin2555]

Good work

[@shomusbiologyofficial]

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[@mayaamer2780]

Thanks 🙏 we r from iraq 🇮🇶 college of medicine in the genetic basis disease

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@Divine_Mortal]

كليات فاشله مالتنا والدليل ٩٠٪؜ من المعلقين عرب😂

[@saranghae3732]

soo good!!!👍🏽👍🏽👍🏽

[@shomusbiologyofficial]

Thank you

[@s.x.6656]

Thank you very much Sir

[@shomusbiologyofficial]

You're welcome

[@rihamadem2461]

You are the best!!

[@shomusbiologyofficial]

Thank you

[@ayanbhar4912]

thanks for making this video

[@asmaasma-kj5iu]

Thank sir lam from palestine🇵🇸♥️🇮🇳

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@asmaasma-kj5iu]

@@shomusbiologyofficial you are perfect l always wach you 🌹🌹

[@babusanthan5128]

🙌🙌🙌superb sir

[@shivaniranote8617]

Thnku so much for such videos

[@zahra2133]

Thank you u saved me ❤🙈💃

[@shomusbiologyofficial]

You're welcome

[@doaayasser3009]

Thank u so much prof

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@ramdev822]

Well done

[@shomusbiologyofficial]

Thank you

[@RABEA-786]

Clear and accurate 👍

[@michealmulolo6477]

wow you are so good

[@shomusbiologyofficial]

Thank you

[@Arpishra15]

Superb

[@shomusbiologyofficial]

Thank you

[@sanskritinautiyal]

Thnku sir 😌

[@shomusbiologyofficial]

You're welcome

[@sanskritinautiyal]

@@shomusbiologyofficial thanku sir for replying ❤️

[@aliatar492]

مع حتراماتي لكل الي درسوني لكن بعد شرحلك هذا خلي يعزلون ويفتحون بسيطة مال لبسان

[@faizanaijaz8340]

Thank u sir bt I need dynamic mutation

[@kanicasharma1105]

sir koi agar aapse question pooch le toh ap kabhi reply kyu ni karte????....kya aap saara ratta laga ke ate ho ya apko ata hi nhi h???

[@timu1973]

Excellent

[@shomusbiologyofficial]

Thank you

[@mohanadahmed5027]

CAT code for valine not histidine

[@محمد-د5ن4ح]

Thx ☺️

[@shomusbiologyofficial]

You're welcome

[@shazinhamasaeed7037]

loved it

[@shomusbiologyofficial]

Thank you

[@Hiralbazala03]

C A T and others are not nucleotides they are nitrogen bases.

[@sojina8533]

thank you so much sir

[@chinaactor9511]

nice sir

[@shomusbiologyofficial]

You're welcome

[@sanskarsharma9683]

UC_ is serine bro Correct it

[@naderanoori373]

thanks a million :-)

[@shomusbiologyofficial]

+zala sehat you're welcome

[@knowledgejunction1643]

Good

[@debabratadas4122]

thank you ...bro..

[@shomusbiologyofficial]

+debabrata das you're welcome

[@yuvirin4688]

thank u✨

[@martinpohshna1110]

Shomu seem like you just woke up... your hair 😁😁

[@shomusbiologyofficial]

Yup. The hair cut got too short

[@swatichaudhury9933]

Wow sir 🙏🏻

[@shomusbiologyofficial]

You're welcome

[@abyssiniamedia7701]

I will get 100 point, awesome

[@shomusbiologyofficial]

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[@eliaskiprono6628]

thankyou sir

[@thekinqom_.]

Nice

[@mhussain438]

❤️❤️❤️

[@shomusbiologyofficial]

Thank you