Gene Regulation

[@rushilbalkundi209]

Watched this man throughout high school AP bio and watching him again for my college bio final. This man is seriously the GOAT

[@FarhanNahin]

im on that first part lets see if i come back for the second half

[@zaminahmed297]

lol yeah I am learning this for my genetic class currently

[@DaFunkmastaFresh]

I'm in medical school aka the third part and yes, he is incredibly helpful

[@salikrajbandhav6858]

7899

[@zhaoshuyu2022]

Same！I just realize I has been watching his videos at different times for 5 years 🤣

[@greenumbrella1]

Excuseme what gene do I need to activate to get that jawline

[@kindcutediamond]

Smooth. Flirting with your teacher

[@kevinfairweather3661]

FOXP2 Gene

[@noratk]

😂😂😂😂😂😂

[@controversialbuttrue8096]

Checking out mewing. Great vids on KZbin about it

[@Zetsuke4]

Lmao

[@AnnosY]

If only my teacher could explain things like this,my life would be a lot more easier! Thank you so much!

[@Bozemanscience1]

Thanks for the great comment. Best of luck with your studies.

[@mariamalmahdy6372]

I swear you are right :( I dnno why our lecturers don't explain things like that I feel that they even make things more complicated .. hopefully none of them will notice my comment lol

[@sooka39]

I have a professor that is impossible. When people in the class ask questions, he never answers them directly. It is so frustrating. Your videos help me so much, and are probably the only reason I am actually passing. Thank you for posting them!

[@Pod0]

My prof teaches with his videos.

[@HeavenlySunset24]

I think some professors actually don’t know the answers so they just say something random.

[@JuicyJuice1116]

"...and I hope thats helpful" Dude...that was WAY more than helpful! THANK YOU!

[@ImTheSleepless]

this guys my teacher in real life for AP Bio...hes so great, its my favorite class of the day.

[@hiyorioh]

Tatsko mbn

[@d25syed10]

how did you turn out my man?

[@wwklk232]

@@d25syed10 drug dealer

[@olympia8374]

This guy works really well, he straight and to the point and he only takes 9-10 mins to explain things where as in class the instructor takes 40-50 mins of just throwing info at you and you don't really get anything out it. Really I appreciate your videos you obviously know your materials.

[@Akosa117]

watching this video is my home work...... shows how much my teacher actually does

[@samanthaweaver2944]

amen to that! my teacher doesn't do crap

[@whc1370]

lmao.

[@patrickallen1330]

yeet

[@Breyerlover4ever23]

At least it's a short (and very helpful) video.

[@andrewsun582]

I have a good teacher and we still watch these, it's for extra support and also we move too quickly because it's AP to explain everything repeatedly

[@Bozemanscience1]

Of course I remember you. I'm happy to hear that you are majoring in molecular genetics. You will be smarter than me very soon. Let's Go Deacons!

[@evan1786]

What lol

[@hifrax]

7 years passed, wondering how Deacons is

[@N3c777]

he's probably replying to a comment. Deacons are probably the name of the university team name. My mans probably in his early career by now

[@jenniferwang946]

Ooop whoever had him as a teach is hella lucky

[@AVITAL834]

The inducer-repressor control of the lac operon is an example of ----negative control----, in which expression is normally blocked. In contrast, the CAP-cAMP system is an example of positive control, because expression of the lac operon requires the presence of an activating signal-in this case, the interaction of the CAP-cAMP complex with the CAP region.

[@samanthalau4515]

See I remember using this video when I was in high school doing AP bio and now I am using it in medical school years later and the quality is still excellent. Thank you so much for your videos and exceptional teaching! Kudos!

[@emileecato5885]

Currently cramming for the AP exam and honestly your videos are the only thing keeping me going right now

[@TyTimeIsAwesome]

30 minutes of reading explained very well in 10 minutes...I would like to thank you on behalf of us lost BIO students!

[@BillPark-ey6ih]

How this guy prepared his lecture is a work of art.

[@abbmohammed9065]

I'm from Iraq and I'm studying med in Romania and thanks to you I have so much clarified out so God bless you.A lot of Romanian students are also watching your videos and they're saying it's so helpful to them in bio classes. Bet you didn't know there are overseas viewrs for your videos.Thanks again.

[@lolopham7295]

My class got booted onto online AP Bio before our teacher left mid-year. Your videos are so much more helpful than the online course I'm taking.

[@HollywoodSunset]

Thank you so much! You explained three first year-bio lectures in a 10 minute video. And it all made sense!

[@ramennoodelz]

i have a test tomorrow and left my book and notes at school...i'm so glad i found a useful and informative video. i am now reassured! thanks so much!!!

[@EgorAnanyev]

Goodness, the most LUCID explanation out there. This is the first time I've heard of this process, and it clicked right away. Thanks so much for putting so much effort into your illustrations, and I'm so looking forward to exploring your other videos in other topics and subjects! I can't thank you enough for your wonderful work!

[@DD-cz6ok]

Thanks! I'm in grade 11 taking AP Bio and I don't understand a word my teacher says! You saved my life. Thank you!!

[@steph6910]

r u married

[@mauricion6608]

Took me 5pages to read all this and my notes are all over the place. Watched this video and learn it all with no problem - Thanks a lot please post more videos Love how you teach.

[@leavesofecstasy6405]

You have no idea how helpful this was, I was staring at the figures in this section of my book for a good 15 minutes and didn't understand a thing and you explained it all in 10, thank you!

[@sccm100]

I feel like I could get an A on this, but I still don't truly understand.

[@CinnamonToast]

this is me with practically all of school especially math

[@saimahramen]

I couldn't have summed up my school experience better

[@sarahyi502]

My teacher has resorted to assigning your videos for homework... We worship you in my class; You are AMAZING. Thanks for all the hard work that went into making all these lovely videos.

[@desireesantos4250]

o.h mY g o d

[@sams3203]

this guy really is the man.. I always watch his videos before i start a new chapter because he helps understand the basics/foundation of everything then i feel comfortable getting into details in my textbook. Thanks a lot Mr.Anderson !

[@KillerSmilEz101]

I was contemplating a change in my major until I stumbled upon your vidoes!! They are very attention keeping (I would know because I am terribly ADHD) and the way you explain everything helps me feel like I could learn anything. I've been pulling all nighters and I still don't want to fall asleep like I do during my lecture. So again, thank you for your videos and all of the knowledge that you have shared with me.

[@Jesuskreis95]

Why can't my biology teacher just explain everything like this! Very helpful, thank you so much. I love all of your videos.

[@karamk92]

honestly the money i paid for this course should be given towards bozemanbiology .................. your videos helped me understand the concept way clearer than the book. Effort highly appreciated. Thanks :)

[@KatariaGujjar]

WoW! This video explains the whole chapter in just 10 minutes. It is way better itself than the lecture we had. Thank you very much Mr. Anderson. -Bio major @ Ryerson University

[@elizabethdelbuono9308]

The Lac Operon is an example of negative control, not positive. I'm confused here lol

[@shesse07]

Also, just to be clear, that article was not my sole source for information, I was just offering it as a resource because I found it to be concise. You do such a great job of explaining, I hope you update and correct this video, because I love your channel and find it to be an awesome resource for students!

[@Friemelkubus]

As a student going for a masters in biochemistry I couldn't do without videos like these. In other words yes it was very helpful.

[@SuperAwsome777]

The Lac Operon can be positive or negative but there example you describes as "positive control" is actually negative control because the Lac operon is off when the repressor is active.

[@bouchraben473]

I'm 5 years late but that's exactly what I was gonna say...that was a negative control

[@SanajaobaChingtham]

this is the first time i can clearly understand about gene expression, thank you mr.Andersen..may god bless you

[@feliscatus4921]

Both lac operon and trp operon are negative control operons because repressors are involved. However, the lac operon is inducible (induced by allolactose) whilst the trp operon is repressible (corepressor tryptophan).

[@Logistical2995]

AP Test tomorrow at 8am. Started studying since this morning. On an (Ir)relevant note. Happy Mother's Day! :D

[@avinashgulati4086]

Dude I live in India and in my high school i almost spent a day or 2 just trying to figure out this operon..reading tens of books but still couldn't understand much. I now realise this is what it means to be a teacher how u explained it marvellously! Me being an average student no teacher near me really cleared my doubts but thank you for ur efforts!!❤

[@chicagogirl4everanda]

Bozeman, your videos helped me through high school freshman bio, AP bio, college bio, and now med school biochem. seriously an amazing resource!!

[@oyvavoyable]

You helped me through honor's bio in high school and now you're helping me through bio 1 in college! you're the best!

[@Resanub]

Professor Anderson, your videos have truly been a life savor for me this semester. I'm taking a genetic course online, so I'm unfortunately missing the lectures that I desperately need. But with your videos, I can get the clarification I need that my book can't always convey!

[@dead2self]

I have probably viewed over 20 of your videos and have found all of them to be very helpful. I was shocked to see that only 2 people have donated on your website (bozemanscience) I'll be adding my name to that list. Thank you Mr. Anderson.

[@norastherin]

i just couldn't listen and had to repeat the video cause i was staring at Paul the whole time... dat jawline....

[@elisegeoris]

You have literally just taught me more in 10 minutes that my teacher has in a month. Life.saver. :)

[@gayanejamgotchian6936]

Thank you SO much. I don't understand why professors can't explain like this. If youtube and people like you didn't exist I'd fail my bio tests

[@shiney94]

Thanks for the info. But i don't think positive regulation is the correct terminology to use for the allolactose binding to the lac repressor. Positive regulation is specifically the binding of an activator to it's regulatory sequence and thereby increasing gene product.

[@elizabethdelbuono9308]

The lac operon is definitely an example of negative control! Not sure why he said positive

[@dredreidel]

most underrated teacher

[@sugar_peas]

I swear this channel saved my life. Idk how i could've gotten through ap bio without this channel. Thank you so much for the help!

[@jongelb9603]

Dr. Bozeman, you might have it backwards at 6:39 According to Wikipedia lac operon is Negative Inducible -- negative because in it's normal state a Repressor is needed to turn it OFF--and Inducible because expression can be turned back on when induced (allolactose). "The lac operon is a negatively controlled inducible operon, where the inducer molecule is allolactose"

[@fluffsalotpie1200]

:) You're an excellent teacher. You've taught me more in ten minutes than my teacher did over the course of ten class periods.

[@Moony385]

it's crazy I was 15 and watching Bozeman for AP bio and now I'm 19 and in Cell Bio and you still help me out! This is amazing thank you!

[@miriamtsukanova8815]

Thank you so much. Mr. Andersen if all teachers were as talented as you, we would live in different world. Your videos are very helpful and informative!

[@Tanvee]

My Pre-AP textbook puts this simple process in such complicated words that it becomes hard to understand. The exact same thing that you said is out in my textbook in 25 pages. You are my hero. I guess I don't have to read my book now. You saved my grades. Thanks man :)

[@Church9456]

Started at 8 tonight. Sleeping after this one. GL to everyone taking the exam!

[@AmeenAhmed1105]

Thanks sir. You've done a much better job explaining than my stuttering biochem professor in college.

[@davidkerling5755]

Great video for clarifying some major aspects of gene regulation. It is almost important to take into consideration the physical state of the chromatin involved in the process for this is another major factor which impacts gene expression.

[@vanessaruizmarin9250]

Thank you soo much. My teacher hasn't taught us a thing this year and this is the only teacher I get even if you're online

[@mariagordon-lewis2802]

Thank you Mr. Anderson.. Your teaching helped me understand Gene expression....especially the LAC operon and the functions and movement of RNA polymerase, repressor and the operator.

[@averrylouise]

Thank you thank you thank you Mr. Andersen! Bio exam on Monday, and your videos are saving me!

[@zxc56km6]

Our teacher showed us a video of a different guy talking about this today. And I was like, heck no I am going home and watching Bozeman. Loyalty!

[@NicolesKeys]

This video is fabulous. You have no idea how many times I've watched it for my biology final tomorrow. Very helpful :)

[@fernandorodriguez6931]

that was very helpful Mr. Anderson I'm IMG and I studying biochemistry after more that 12 year , and your video with all the explain graphics really helped me out

[@walaasalman4476]

Thanks a lot ..your videos are so informative and well done.. Lac operon = negative control bc transcription occur only when repressor fail to bind to the operator Trp operon = positive control

[@aznngg]

i really appreciate your work. you have helped me immensely in understanding biology - sometimes when you're reading pages on pages of text from the text book none of it is absorbed. This interactive video really captures the ideas and concepts the textbook is trying to explain, so thankyou

[@lilsavage8265]

I KNOW THAT MY TEACHER SUCKS AT BIOLOGY BUT WHEN I CAME THREW THIS CHANEL I GOT A A+

[@ufo8mykat]

10,822 views, and 28 comments. That's crap. You have a wonderful way of describing things and I hope you understand that your efforts matter.

[@nickcolejackson6884]

Thank you Mr. Anderson, I am in Medical Microbiology and I did not understand this concept by just reading the book. I am so confident that I understand this more . I Love this video that I am going to send it to all my friends and professor to show the entire class.

[@Eztini]

Greetings from several medstudents at charles uni in Prague! Very helpful, thank you!

[@kimbo5260]

Thank you! My lecturer spent an hour explaining this and I did not understand anything. You made this so simple to understand!

[@WassimMekatel]

If only my teacher could explain things like this,my life would be a lot more easier! Thank you so much!

[@andresvodopivec5950]

You are absolutely the best teacher to explain all this things. Thanks for your time and dedication

[@Meg-zu8fi]

Thank you so much. I’ve leaned these educational videos on KZbin are better than my teacher for biotech.

[@Bluestain36]

Idk how I'd get through AP Bio without you

[@helishah6903]

been watching your videos for two years...always a GREAT help. Thank you so much, Professor!

[@lychee159]

tomorrow is my test i think i had a grip on this. thanks to you!

[@HAVIRULZ]

Better than how my professor was trying to teach, you rock man!

[@OwenTheWIld]

Thank you so very much; I pay big money for "an education", and you explain it better int en minutes than in ten lectures. Thank you!!!

[@shanisespencer207]

You make everything so simplified. Thank God for you.

[@KutePrincess95]

Compare this to the online lecture that my instructor just created for us, I prefer your lecture much more than hers. It's easier to understand, though.

[@tnasty9209]

I just learned in Microbiology class that the lac Operon is both Negative and Positive Regulation. It is negative due to the repressor being bound to the operator by default. BUT when glucose levels are low, cAMP comes along and binds to CAP, this allows CAP to bind to the Promoter site and allow RNA Polymerase to bind to the Promoter and synthesize B-Galactosidase; all of this can only happen if the CAP is on and the repressor is off. The repressor comes off in the pressence of allilactose.

[@tylerpaquin4004]

Amazing explanation, great animation and idea map at the beginning.

[@scrufy447]

Thank you so much for this. I missed this lesson at my school and the textbook was not helping. Now I think I am ready for my test.

[@bethkeady7025]

I am taking a graduate genetics course, but I come here for the basic explanation. He does a great job

[@DS-be2te]

great video, but i hoped that you would describe the gene regulation in eukaryotes more precisely. but it still helped me to understand this process better

[@AP_505]

I missed some lessons on this but understood everything perfectly thanks to this video! A lot of videos are only good for revision purposes so you only understand them once you've already been taught the topic, but this video was excellent for someone like me who hadn't visited the topic at all.

[@romierobertson6559]

Everytime he said "or not," I couldn't help but to think "OR NAH"

[@justincronkright5025]

NAWT... I do enjoy my 'O's! But it seems most people do not.

[@switfranc]

I agree with most people here, the textbook is just words-packed and just doesn't get into my mind. But this video and easy animation, it just make sense and I now understand it.

[@christophersalvador8380]

You saved my life once again!

[@MsSd211]

Thank you Bozeman Science for getting me through my biology class!

[@DanielCH95]

Mr. Anderson, you've just earned yourself a subscriber. You and I are going to become very good friends over the next 7 months! That AP Bio exam is GOING DOWN.

[@caseyriddell7185]

These videos have saved my sanity in my AP Bio class. Keep doing what you're doing, it is so appreciated!

[@Sveccha93]

Excellent as always. Two classes and three different textbooks couldn't reach me with what only took 10 minutes here.

[@JenniSola]

Saving my biology grade right here. Rebecca Crisman this is a much better explanation than the packet gave.

[@danielnasr7570]

Bozeman Science you are giving science from all your heart, that is how our profs. need to do. god bless you man.

[@lolann77]

Lac operon is negative control because it's initially switched off with the repressor and needs the presence of lactose to be switched on. Same for trp operon. An example of positive control is the lac operon with the CAP (catabolite activator protein), where both lactose and glucose is present, but glucose is scarce (E. coli prefers glucose). When glucose is scarce, the cAMP (cyclic AMP) accumulates to notify E.coli that glucose is scarce. With the presence of cAMP, RNA polymerase binds to the promoter and stimulates transcription. (from my bio textbook)

[@sabinamcnally1995]

I love the animation and simply stated explanation. I also wanted to mention an error. The trp and lac operon are examples of negative control because they involve repressors. Positive gene regulation would involve an activators.

[@umamudgal1294]

I appreciate your slide. It helped me to teach Standard 12 students in my class. The topic is simplified. The vedio is also liked by My students. Thanks for such a useful vedio.

[@priscilaundomiel3264]

Thank you so much for your video. It helped me a lot. Now I can understand more about the operon lac. You are a great teacher! Please continue like this! ❤️

[@lonkarkalyani]

Thanks a millions.... Just loved it.... Got ma exams in like 2 days... N reading from notes is like burning in hell... But u really cleared all my doubts in REGULATION IN GENE ACTIVITY... Loved it... Thanks

[@hirusandutharumuthumadduma7478]

Campbell biology book 10th edition says"regulation of both the trp and lac operons are switched off by the activate form of the repressor protein. " but you may feel that lactose binded repressor make the transcription work. But remember that activated repressor means it can bind to the promoter .so lac repressor is activated as the moment it is made. That means ,it's intact form is activated. But the way that you may think , i mean the allolactose (the isomer of lactose formed in Small amount which actually bind with the repressor) make the gene active is not totally wrong. That's why Campbell says trp operon is a repressible operon and lac operon as inducible operon.**(Campbell biology 10th edition page 418 419 420/ unit 18)Both operons are pertaining to negative gene regulation and example for positive regulation is catabolite activator protein (cap regulation). Bozeman is not wrong and the case is about terminology. The (positive) must be corrected as inducible and negative must be corrected as repressible.☺

[@gailgarceau13]

so helpful, thank you Mr. Anderson

[@nisamarinixD]

I have an exam tomorrow and this helps a lot. Thank you!