Gibbs Donnan equilibrium and membrane potential

[@plabitapaul5696]

What a beautiful explanation.. From 2days I was hunting for the concept.. Something was missing, which was beyond my understanding.. We all know nernst equation.. But every book does not put the concept of donnan's effect.

[@ThePhysiologyChannel]

I appreciate your feedback so much!Happy learning!!

[@ThePhysiologyChannel]

Brief introduction for GIBBS DONNAN in my new video. kzbin.info/www/bejne/n2KvcqeBiaqmjJY

[@muqaddashanif6401]

Explaination in such a sophisticated way✨

[@duaasaeed501]

Nicely and simply explained!

[@faizanwani_]

Very good explaination!

[@a.rahman.t]

nailed it bro, nice explaination

[@capitalistcommie6846]

Sir please keep making videos...you are a boon to this world... Even if 1 student benifits from your videos it will add to 1 good doctor Never stop making these videos

[@ThePhysiologyChannel]

Thanks for the kind words. It reminds me the purpose.

[@SupunChathurangaBandara]

Thanks for the video 😍😍 It was really great and simple.

[@gokulakannansarathy1010]

Very well explained

[@Pulkeshwara]

Superb explaination❤️❤️❤️❤️.....sir pls upload more videos 🥰🥰🥰🥰🥰

[@ThePhysiologyChannel]

Thanks 😊

[@dhruvpandey8880]

Hello sir This video definitely helped me as to understand how donnan effect will be a factor in generation of RMP. Sir but according to the equilibrium the product of the permeable ions on both sides should be equal. However according to your first example,if there is an electrical gradient between the two sides,the product will not be equal

[@ThePhysiologyChannel]

Good Observation! My intention was to give theoretical understanding with simple numbers, so I overlooked the ratio. As I mentioned in the video Cl- Ion is permeable will also redistribute with slightly higher concentration B. So, instead of 5 on both sides, lets make it 6 outside and 4 inside. Now Donnan ratio K [A]/K[B] = Cl [B]/Cl[A] = 1.5. (The numbers are meant only for understanding the concept). All the best Dhruv. Sorry for late reply, somehow it slipped my mind.

[@ThePhysiologyChannel]

Brief introduction for GIBBS DONNAN in my new video. kzbin.info/www/bejne/n2KvcqeBiaqmjJY

[@sheikhhasan9639]

Thank you so much. Very a helpful video..

[@ThePhysiologyChannel]

You’re welcome 😊

[@muggle111]

Thanks for the video...It was really great😊😊

[@ThePhysiologyChannel]

+Rashmita Das you’re welcome. Thanks for the feedback

[@sparksfly759]

So explicitly explained!:)

[@xiaozhu7219]

both side are electroneutral, only at the membrane interface, one side is more negative charge distributed at the interface between membrane and side one. So the deduce of potential is wrong ! it said one side has excess+3 charges while other side is -3 net charges, no ,they have no net charges within themselves!!!

[@navyapharmatech123]

God bless you sir

[@shadmanrashid9991]

thanks man.. helps a lot

[@sandipgharui2566]

Thank you sir

[@afiatasneem4802]

Thanks a lot

[@ThePhysiologyChannel]

You’re welcome

[@rosemaryjoseph3768]

Thanku so much....

[@ThePhysiologyChannel]

You’re welcome

[@navyapharmatech123]

Wow wonderful explanation sir

[@ThePhysiologyChannel]

Thanks!

[@praneet9396]

Gr8 explanation....👌👌

[@ThePhysiologyChannel]

Thanks

[@mindframeyt]

supop i love it

[@amritsharma5373]

why is the layer impermeable to Na ions but permeable to Cl ions?

[@ThePhysiologyChannel]

AMRIT SHARMA In most cells sodium channels are closed at resting membrane potential, so permeability of membrane for sodium ions is low. But, chloride ion channels are open at Resting membrane potential, so membrane is permeable for chloride ions.

[@amritsharma5373]

Thanks. But what is the reason behind the closing of Na channel and the opening of Cl channel at resting membrane potential?

[@muqaddashanif6401]

@@amritsharma5373 I am not sure but I think it is because of confirmation changes(structural changes)of Na channel which make them active in action membrane potential as they respond to voltage(voltage regulated gates).

[@meenakshibisht3556]

In donnan effect it is said that there is charge neutrality in both compartment but here there is net charge... Please explain it