HIGH RISK DRUGS (Preregistration exam, GPhC framework)

[@PREREGSHORTCUTS]

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[@RuaTheFox]

Thank you!

[@vijaybhavan6482]

Opioid interactions - I think it should say effects reduced by INDUCERS, not inhibitors (correct me if I am wrong)

[@preregshortcuts9474]

You are absolutely correct Vijay . Correction. Was meant to say INDUCERS on the slides e.g rifampicin. This was corrected on the course. But thanks for highlighting

[@johnklein3255]

Actually the video is correct. This is due to most opiates being pro-drugs. An increase in metabolism due to a CYP inducer would mean an increase in the active metabolite (morphine) thus leading to a greater therapeutic effect. So Vijay is absolutely incorrect 🤯

[@chrispa6299]

@@johnklein3255 nooo an increase in metabolism would mean active metabolites would be turned into inactive metabolites faster

[@johnklein3255]

Chris pa no you don’t understand the concept of a “pro-drug”

[@chrispa6299]

@@johnklein3255 go back to school bro dats basic