Histopathology Skin --Malignant melanom

Histopathology Skin --Malignant melanoma

[@gaianeko6893]

I can't believe that a video from 15 years ago would be more helpful than my histopath professor. Whoever you are, thank you. Sincerely, a med student from the future.

[@WashingtonDeceit]

yeah, a multipolar mitosis is generally regarded as a cancer cell, i can not think of ever seeing a MPM in a cell that wasn't

[@WashingtonDeceit]

@Lara Gravenor Yes, very easy to tell the difference microscopically.

[@euripidesroumeliotis6136]

Dear Dr Minarcik, you have done an excellent work. Thank you for all the cases you share. Greetings from Greece

[@DrGondim]

Thank you very much! Greetings from Brazil.

[@hlhover]

Thank you for doing this, I've had 3 melanoma's and a lump now has formed near an old site that I had surgery on and I'm trying to gather information before I see the Oncologist next week. I hope the lump is just a fatty benign tumor. All of mine were Clarks I or II, so I was very fortunate.

[@user-ii9mv7jj9i]

عادك عايش؟

[@enochbrown8178]

Simply outstanding!!!!

[@WashingtonDeceit]

Doesn't it make sense that if basal cells are normally palisaded, then wouldn't it make sense that basal cell carcinimas are ALSO palisaded?

[@SuperYersinia]

But they are palisaded aren't they?

[@kirstenmcghie8458]

This is so extremely helpful, thank you for sharing your knowledge

[@muslimalhamdulillah3739]

May Allah bless you Sir

[@ELPaso1990TX]

Thank you very interesting. I noticed those nuclei look quite big and nasty and no doubt irregular in shape with dense chromatin.

[@laurence132]

thank you, Very well presented . laymans key to detecting a melanoma is look for ANY change in a mole . unfortunaely the nodular melanoma presented at the begining often begins vertical dermal invasion early. micro mets are probably present

[@nomanullahshah6217]

Awsome explanation

[@djalitanaful]

thank you

[@Hautchen]

Thanks for the description, great!

[@WashingtonDeceit]

of course, if the new "scar tissue" really turns out to be melanoma on microscopic examination, prognosis could be guarded long term many melanomas can respond drastically well to immunotherapy wdc

[@shagulhamad1948]

You are so great at explaining

[@agentdark64]

Geez, it look so straight forward determining if it's melanoma. I always worry the pathologist got my diagnosis wrong

[@hagarkhallaf991]

Thanks a lot

[@ragia_forgiveness]

Thanks so much

[@keili1989]

thank you :)

[@vigneshrajasekaran6016]

What, or are there any key visible characteristics of malignant melanoma in the cells during a skin biopsy that separate themselves from healthy skin tissue?

[@WashingtonDeceit]

It IS easy if you ignore all those pompous geeks who have their heads up their asses.

[@svetruccio]

Is there a way to identify the capillaries in the papillary dermis?

[@sangithamanasa6144]

My father affected which treatment gud

[@prachibhattarai3833]

thank u prof...

[@ThànhTrần-333]

Professor, could you please upload a video of subungual melanoma?

[@MrMaddox57]

god help this person. THAT is cancer. Heaven forbid, this person is either dead or in serious trouble. Thank you for these videos. That is an invasion that the body cannot stop. That is awful. That one tumor has probably reached every organ outside the brain, heart.

[@ebutuoyindiapratham]

What is the mechanism of pallisading in basal call ca.?? Why it doesnt happen in squamous cell or melanoma??

[@cuentodenada]

how does the number in the top right corner correlate with the actual magnification? Is it that number times 100?

[@lenaywoo59]

How does melanoma affect the tissues?

[@LA7ZAHIA]

❤❤❤❤❤❤❤❤❤❤❤❤❤

[@Dr.Z.Moravcik-inventor-of-AGI]

I wonder if I get answer after so many years? What exactly is the melanin inside the cells? I see cells rounded by dark violet color and inside is cell nucleus of dark violet color. The rest of the cell is usually white that means nothing more visible is seen there. Where is melanin? Some of the cells have additionally small violet points spreaded in the cytoplasm around the nucleus. Is this melanin or are these some organelles?

[@WashingtonDeceit]

Any dark visible particle in a melanocyte that is MUCH smaller than the nucleus, is melanin.

[@ninagavrilova783]

By vertical growth we measure to the end of melanocytes with pigment right ? Is that the end of the tumor?

[@WashingtonDeceit]

Generally, the top of the tumor to the deepest part of the tumor.

[@mlkopituras]

horey class shall be passed xD

[@muslimalhamdulillah3739]

Thank you

[@shagulhamad1948]

You are so great at explaining