How designing brand-new enzymes could change the world | Adam Garske

[@KnightsWithoutATable]

I used to use the enzyme and plant based detergent when it first came out under the Arm&Hammer brand. It was one of only two detergents that would get the hydraulic oil stains off of my work cloths, the other being Tide for HE washers and cold water. The branding switched to Purex and they diluted the concentration significantly enough that it was more cost effective to just pay for Tide instead.

[@funny-video-YouTube-channel]

Enzymes will wash off dark stains. Great for all the washing we do on our planet !

[@pglove]

Washing machines in Japan are run on cold water. If you want warm water you run a hose from your bath and reuse that to do your laundry.

[@thefishstick]

Oh those enzymes and their shenanigans

[@huskymotivations]

It is a famous quote that "I can" is more powerful than IQ

[@GrimJerr]

When I first imagined an enzyme that would help us digest all of the plastic debris we have polluted the Earth with I thought it would be a good idea. After thinking about it for a while I realized such an enzyme would also compromise virtually every seal or measure we have to keep things fresh, dry, or in a controlled environment.

[@XX-pl9wp]

The best talk of our age

[@mikesnider8234]

Plastic destroying enzymes in the nation's water distribution system would be a disaster....

[@aurelienyonrac]

Smart comment from a smart man.

[@Olwwolf]

Definitely something to think about before application! But it would still be useful I think, for example to degrade plastic before it even gets into the ocean in a controlled environment

[@aurelienyonrac]

@@Olwwolf A controlled environment like the one for radioactive wast? You just invented a job for a lifetime! Along asbestos and garbage. It is all buried in the earth we are made of. I wonder if the slow introduction of plastic, metal, plastic eating enzime and chimicals into our body is part of a plan to make us into cyborgs...

[@prathameshhalade8230]

I guess the use of enzyme would be limited to convert plastics into monomers which are less noble and thus can be chemically treated further. It’s now like treating a piece of discarded cloth, which we can do very well. We can also reuse the monomers or Oligomers thus formed by application of organic chemistry.

[@aurelienyonrac]

@@prathameshhalade8230 intresting. Thank you

[@mmmmmmichael]

That was excellent

[@marypinakat8594]

8.03. What is in the horizon for enzyme building? Great!☆

[@nasamansaxena5371]

What about the disposal of rejected enzymes

[@prathameshhalade8230]

Nasaman Saxena just heat them and the protein structure would be deformed and the amino acids reused in the ecosystem.

[@KristoffDoe]

I'm always a little bit annoyed when amino acids are presented as those uniform "balls" which are just sitting there on a string and then string is magically coiling, and then protein is just this nice smooth ribbon. The truth is that each one of those has different size, shape, and phys-chem properties - charge, hydrophobicity etc. It is NOT "pearl necklace" - it's more like a necklace made using one of those DYI "make your own necklace" kits with many differently shaped objects. And that's why protein make the shapes they do, that's why enzymes work the way they do - because of all of those shapes, sizes, and forces.

[@cowboys4life418]

i agree i didn’t care too much for that simile he made. you’re right it is a lot more complex, enzymes include so many factors like what structure it is in; primary, secondary, tertiary, quaternary. it gets more and more complicated with processes like molten globule, different bonds between each a.a., hydrophilic and hydrophobic interactions and so on and so on. but for a short 12 minute speech it’s hard to cover all that so i don’t blame him

[@ChristineBeltran]

Good talk.

[@stevechapo327]

This and another Ted talk I saw on biofabrication makes me think that amazing changes are on the horizon.

[@elainezhang1493]

Question: how can you make an enzyme that can dissolve proteins on your woolen shirt without dissolving the wool shirt itself. Wool is made of proteins.

[@seangrimes1]

Loved it

[@YouAndImpact]

Great video.

[@_karannawale]

Amazing

[@WASSWADAVISHD]

Great content in your box video❤️❤️❤️

[@melanieharris8419]

Very Interesting

[@glamdrag]

i hope that next time when i see a firefly i won't think of enzymes

[@lavalove01]

hahah

[@aurelienyonrac]

Right?

[@gigglysamentz2021]

Enymes are the bessssst!!! OUO

[@jaydentoker6542]

Did I just watch a 13 minute detergent ad?

[@aurelienyonrac]

Right?

[@marypinakat8594]

Jayden Toker, NO. He did talk about Health, Environment, lilacs, fireflies and everything in nature.

[@aurelienyonrac]

@@marypinakat8594 i will pay closer attention to adds next time. Thank you. On a different subject i vote for an ted talk on "Information, news, advertising and propaganda". What a slippery slope.

[@marypinakat8594]

@@aurelienyonrac ☆☆

[@griff420blazer4]

What happens when the enzymes enter the environment?

[@glamdrag]

@Martyr4JesusTheChrist I guess they're doing a better job than god is doing. Where was he when we needed enzymes to wash the blood stains from our underwear after chipotle night?

[@iluan_]

Enzymes can't replicate on their own and they degrade over time. So, after a couple they would break down. Also, bacteria and yeasts would absorb them just like they absorb any other protein. Now, the interesting case comes when instead of just the enzyme entering the environment, the organism that makes them enters it. Basically, the organism will be wasting its cellular resources into making the enzyme instead of spending them on growth, unless the enzyme gives a significant advantage to the organism then it's likely to dissapear due to natural selection.

[@prathameshhalade8230]

Enzymes aren’t plastics which won’t degrade and they are also already present in the environment (you digest food with them, you think, walk, produce heat, and do crazy work with them). Also enzymes aren’t required in tonnes so that they are easy to handle. They are simply proteins which could be degraded. You are not horned with all the enzymes that you need your whole life, your body makes them on regular basis and also degraded them (it’s like leaves of tress, they produce them for photosynthesis and then comes fall). Enzymes degrade automatically as there is huge variations of pH, temperature, and other factors in the environment.

[@zawsrdtygbhjimokpl6998]

this, seems harder than programming. I feel like in programming you can know the main things like a few languages and sure there is modeling and many other computer-oriented professions, but chemists or whatever he is, their jobs seem harder as less I assume work in these fields. People who make better batteries, who make medicine, who make the hardware of electronics and in a way humans- they are precious. I feel like anyone could replace me in C++ and similar, but I don't think they're common enough. I don't recall the last time I saw a joke about enzymes in 9gag for example

[@NoSkillsNoFun]

I study both fields trying to become a teacher. Before I started, I had a little exposure to computer science, basic java skills and some SQL, but no chemistry in years. But I thought it'll be alright and I should focus on my programming, as it is the hard part. Damn was I wrong. Programming, despite being tough at times, always follows (often) a simple logic. And writing it, depending on the language, can be learned like a language as well. But chemistry....there is so much stuff going on, so much you just have to know, stuff you just have to memorize the way they are. It's really fascinating though, especially because I voted it out of my courses back when I graduated from school. I basicly started from zero, because 10th grade chemistry is basicly of no help in university.

[@melissablick779]

People doing enzyme design tend to do quite a bit of programming as well. Analyzing the data for each batch of enzymes and generating subsequent candidates for the next run require some serious programming. Proteins fold into those intricate shapes he showed and that's a complex process. Randomly replacing amino acids often might mess up the folding drastically. Since actually making new enzymes to test is expensive, you'd code up a bunch of simulated models to check if these candidates are even slightly viable. In short, this kind of work requires serious skills in programming, chemistry, math and physics.

[@zawsrdtygbhjimokpl6998]

@@melissablick779 but I see programming skills to be more common. The appeal for learning the fairly programming and programming + a field that has more risk than it (since you can program from nearly any device) seem vastly different. A field in which you need to grab things, tinker, I believe they also have less tutorials, thus more expensive and less taught on the web

[@zawsrdtygbhjimokpl6998]

@@NoSkillsNoFun joke's on you, programming only taught me the basics compared to what university had in store. I could've entered it with 0 programming skills and that would've been fine, I would've just needed to learn faster, that's all. I guess that's to be expected when you go from 1 hour of programming per week to 10 hours and also they demand more per hour

[@NoSkillsNoFun]

@@zawsrdtygbhjimokpl6998 During my time at school I didn't have any programming lessons. I studied computer science and media at the university prior to switching to computer science and chemistry as a teacher. I went into my first enrolment without any knowledge about programming and it was surprisingly manageable.

[@jakariaofficial1289]

from BANGLADESH

[@yd3334]

Ok

[@glamdrag]

@@yd3334 from RUSSIA

[@jollygreenjeff2640]

From UNITED STATES OF AMERICA

[@GuitarZombie]

Lets screw with stuff and see what happens

[@yeoman588]

A perfect description of scientific research and technological innovation!

[@whocares4592]

Imagine how the idea of flying in a machine sounded like when first proposed, now look at comercial planes...

[@АндрейЛуценко-х2ш]

Не от экспериментов ли с ферментами появился короновирус ?

[@joelvega6755]

...

[@kazuya99ace]

DIY Corona Virus Tutorial

[@joelvega6755]

NO MORE ROBBING JLTV AKA ...

[@batrudinjamaludin750]

1st

[@batrudinjamaludin750]

Alright, thanks for the advice

[@glamdrag]

@@batrudinjamaludin750 I'm not nearly as cool as Jesus, but i think it's awesome that you're first. Hope it count's for something

[@joelvega6755]

Zoom 010

[@joelvega6755]

Zoom out 010

[@melowsito9490]

I am the therd woo

[@yd3334]

*third

[@owen9517]

@Martyr4JesusTheChrist gay

[@glamdrag]

@Martyr4JesusTheChrist he's third tho

[@arsenymakarov6961]

​@Martyr4JesusTheChrist is that your inner monologue to yourself? Gosh, you're so judgmental towards yourself. Take it easy, get a therapist or something. No need to get so worked up for a harmless stupid joke in the comments.

[@KlimovArtem1]

He seems so nervous.

[@martinridge4869]

You are just a Corporate mouthpiece

[@GrimJerr]

"We can.....design. stuff that's not in nature", isn't that exactly the premise of every crappy 'B' sci-fi movie we've ever witnessed

[@wille2680]

How come every time one of these geeks come up with a bright idea we end up dealing with the unintended consequences?

[@iluan_]

Care to give an example?

[@wille2680]

@@iluan_ Plastic.