How do Psychotropic Drugs Work?

[@kevinwick597]

Endlich ein neues Video!! :) Freue mich sehr!

[@Jasnogorodskij]

Danke vielmals Herr Prof. Gründer! Die Arbeit von Ihnen und Ihrer Kollegen am ZI Mannheim ist immens wichtig, um einen lang überfälligen "Turn" in der Pharmakotherapie einzuläuten. Ich hoffe inständig, dass die angesetzten Psilocybin-Studien am Johns Hopkins und dem Imperial College London, auf welche sie im Vortrag indirekt verweisen, uns diesem einen Schritt näher bringen.

[@lucabusch6093]

Super!

[@vampire8568]

Ich liebe Ihre Videos! Dankeschön

[@torstenschlaberg8058]

Schöne Weihnachten ihnen und guten Rutsch ins Jahr 2020. #

[@oooodaxteroooo]

19:13 Is it just me or does this graph show ONE major thing? So people who get actual anti-depressants have a similar recovery path to the placebo-group. However, there are people who SUFFER from anti-depressants. Basically that group stays the same - its a flat line, lets not kid ourselves. More in detail, ALL groups show the biggest improvement in the beginning. What happens in the beginning? They meet a doctor. Could it be that what is actually helping all the groups in the beginning and the others over time is connection, i.e. a break in loneliness? Maybe the ones that dont respond to the anti-depressant were simply left alone, didnt care for themselves, because they thought, the anti-depressant will do the work? Fix themselves magically? The placebo group surely didnt profit from the drug. So what else but therapy did they respond to? Maybe the group responding to anti-depressants simply also found the right therapist and took their issue seriously. But since they basically have the same path as the placebo group - its WASNT the drugs that helped. It was THERAPY, other people, breaking loneliness and developing self-responsibility. More simply, shouldnt we simply look closer at the placebo group, because it shows that anti-depressants arent needed? Find out what caused their remission and instead of treating the first group with anti-depressants, causing a flat line and no recovery, treat them the same way as the placebo group! Study connection, responsibility, trust etc instead of pills. My 2 cents.

[@oooodaxteroooo]

23:20 this also brings us back to what you said about the evolutionary advantages of "brains" susceptible to depression. If humans always worked like this and there WERE no anti-depressants. How on earth did those people survive? Yes, modern society may trigger it more, but shouldnt people have had stressful phases before? Hunger, war etc come to mind. Did all these people just have children early, before the onset of their disease? Schizophrenia e.g. develops late enough to occur after conception and childbirth. Still, isnt it very likely, that we really dont NEED anti-depressants? That the problem is simply the way we live? If that were the case, moreover, having anti-depressants that WORK, would make our problems as a society worse, since we would fix the root of the problem, but instead put people on anti-depressants!

[@kareendeveraux1847]

The problem with psychotropic drugs is simple, that the brain adapts to them, the effects, desired or undesired, are more noticable in the beginning of the treatment. To have the same effect, the dosages are increased or other drugs added. In case, patients want to come off, they have to go through withdrawal (that goes for ALL drug classes, ALL are creating dependency). Then in some cases they have so heavy withdrawals they slip into schizophrenia, or seizures or even death. Then psychiatrists can add more drugs, or have them committed. This is all a dire scam and many die or commit suicide. (They blame it on the mental illness.) In some cases schizophrenia is caused by vitamin b deficiencies. b1, in case alcoholism is involved, b12 in case of coffee/nicotin/anasthesia. I personally think post partum psychosis can be caused because anasthesia drains b12, especially if nitrous oxide was used (women even died due to the neurodegenerative processes). The sad truth is, psychiatry isn't interested in solving problems. They are after the money and there is no money to be made with healthy citizens.