How Does Prostate Cancer Kill Us?

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How does prostate cancer kill us? Leigh Ellis, PhD is the Scientific Director of the Urologic Oncology Program at Cedars-Sinai Cancer. His work within the lab focuses on genetic and epigenetic mechanisms behind prostate cancer. Dr. Ellis discusses prostate cancer metastasis with Darryl Mitteldorf, LCSW from Malecare.
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[@F8Tributo]

Meandering interview? Any cell, in any part of the body can be "insulted" by external forces- carcinogens, EMF, hypoxia, etc. Once the cell mitochondria has become compromised, the cell can no longer make ATP through oxidative phosflorylation for it's energy. The cell is relegated to using the process of fermentation, using glocose and glutamine as fuel, sans oxygen. In contrast, normal cells are not confined to using glucose and glutamine, but instead are "flex-fuel" and can still make ATP (with oxygen) thru oxidative phosflorylation, using ketones for their fuel. A ketogenic diet reduces serum glucose, and intermittent fasting helps reduce glutamine, weakening the cancer. Any cancer, any part of the body. If needed, focal ablation can now be used more effectively, without necessarily toxifying the patient. Note that the mitochondria dictate the DNA of the cell nucleus, and this results in ensuing genetic mutations. But the mutations are not the initial "insult" that damages mitochondria, they follow precipitously, and that cell becomes undifferentiated. A healthy life always means avoiding known "insults", keeping the BMI well within guidlelines, avoiding sugar and processed flour, eating lots of cruciferous veggies and healthy fats like salmon and avocados, regular strenuous exercise, etc. Following these guidelines will vastly reduce any chance of cell disregluation, and slow or stop the growth of cancer if it has already become a tumor. After treatment with the SOC, there is often "biochemical recurrence" of cancer. This isn't puzzling, if the metabolic environment of the body has not been addressed- You can cut dead leaves off a tree, but if the root problem is not addressed, the dead leaves will come back. Can't just pull weeds in the garden, they'll just come back. The metabolic environment of the body has to be changed from what it was when the mitochondria first became damaged, otherwise it's just lather, rinse, repeat, like a never-ending groundhog day.

[@kentwright5346]

I have never before copied and saved a comment from KZbin. Thank you!

[@LukeDohner]

Very informative, thanks for making this video.

[@symosys]

It’s been 2 years since this was published. Could you do a follow up on how your research has progressed? This is fascinating discussion.

[@stormwalker321]

Thank you both very much for your time,and generous sharing of information...it helps when we can understand these things ...thank you very much

[@hectormarrero4794]

❤❤❤

[@richardbennington323]

Remind me not to have you come and speak at are prostate cancer support group. There are new drugs coming out . I think you need to touch on those. Thanks for your input and your time. Think I'll stick with my doctors at the Cleveland clinic

[@jabster58]

Why in the hell would we want to know that....

[@marknorton5951]

I’m sorry, I know you mean well but you need to work on the fluency of your presentation, cut down on the jargon and stop interrupting each other.