How Long Does Prednisone Stay In Your System

[@NomadMonster]

I was prescribed 20mg to be taken once in 24hr. I did that for a while... starting at 8AM in a LOT of pain, took 20mg and it took five hours before the pain would start to subside, then at about 10PM, the pain returned with a vengeance and lasted until the next dose. I switched to two doses of 10mg (morning and night) then I could at least get some sleep. With that much pain insomnia was not an issue. Now doing OK with 5mg each 12hr apart and only mild symptoms. Thanks for the series, certainly help understand.

[@AngellaSpinney]

I feel that patients that are prescribed medication should know the pros and cons of what a medication can or won’t do to your body. Most patients are unaware of the prolonged effects of certain medications. Knowledge is power. It gives you the power to make a correct decision for your body. Some patients like myself had side effects that even my doctors couldn’t explain. Also we must remember that everyone doesn’t react the same to medication. Test studies aren’t done on the individual patient, which would be impossible to do. So each individual should do their own research and decide for themselves if that medication is best for them.

[@juliamcclelland3434]

Thanks for this channel. Prednisone although helpful for my illness has been Hell On Earth. The side effect profile is just sickening, literally.

[@PrednisonePharmacist]

You’re welcome! Your description is too true: both heaven and hell in one tiny package.

[@deliajones2201]

I'm a nurse and took pharmacology. I have forgotten. But it all rings a bell. Hardest course for me. Corticosteroids was tested on with tricky questions. So was those half life questions

[@rlynn5390]

I was on it for skin inflammation and for about 10months I gained like 50-60lbs and it took years to get off, now sadly I’m back on it😢 but I was desperate for relief

[@spatelier]

Given Prednisolone seems to be frowned upon by all and sundry, I have noticed that it is so often prescribed by as a drug of last resort by many practitioners for a host of mostly inflammatory conditions. I have also read so many scare stories about its adverse side effects, but there is rarely any mention of what dose the patient is taking. I would hazard a guess that in most instances it was ridiculously high. It is very important to understand the difference between a 'physiologic' and 'pharmaceutical' dose - a piece of information rarely mentioned including this video. The former is a dose less than the amount of cortisone produced by the body (approx 35-40mg per day). The latter is anything that exceeds it. Most problems arise with a 'pharmaceutical' dose as the body starts relying on the drug to produce the cortisone equivalent and that is why it is necessary to taper off the drug slowly to allow the body to start producing it's own again. Whereas at low 'physiologic' doses of around 5mg or less, the body is still producing cortisone, so it is possible to stay on the drug for longer periods with little of no side efferts. As the video mentions, it is also important to note that this drug will effect people in different ways. I have found the drug extremely effective with very mild if any side effects and I have been taking it on and off for years! But other are evidently not so fortunate. For me it's a quality of life decision and I try to be sensible based on the information I have discovered about Prednisolone. I wish there was more concrete information based on proper studies but I suspect there is little incentive to do this given the patent for it has expired, so there is no money in it for Big Pharma! Plus there are plenty of other drugs to give to patients which do turn a healthy profit. However I have yet to find anything that comes close to the effectiveness of Prednisolone for my condition and it has turned out to be a life saver on several occasions. Finally, can I suggest that those serious about researching this drug try get hold of a book called 'Safe Uses Of Cortisol' by W Mck.Jefferies. This is the most comprehensive study on the subject I have found, and will prove a mine of useful and insightful information for anyone thinking about or taking glucocorticoids. It's mainly about Cortisol but discusses Prednisolone and other man made versions. It's also full of actual case studies where patients being treated have had their lives transformed as a result . Unfortunately the book is hard to find and usually extensive, but well worth the investment if you manage to find one.

[@sherryblatt4459]

Spatelier I agree with you 100%!! Everyone is different! I was told that I can’t be on prednisone for very long because of the horrible side effects! If I don’t take it I cannot move in the morning!😢For me what is the alternative? I saw a new rheumatologist last week and she wants me off prednisone and wants me to start on injections of kevzara! I read the warnings of taking that drug and I will take my chances with prednisone!! Although now my family doctor won’t be giving me anymore prednisone and my new rheumatologist won’t either! I believe you are right about big pharma not making out on prednisone anymore and these other drugs are benefiting them money wise!! I want to cry!!!

[@kennethbutzer4467]

The health of your adrenal glands play a HUGE role in your recovery from prednisone use because let’s say your adrenal glands are very low functioning due to chronic stress or illness for years and they were already producing sub, optimal cortisol, the prednisone, which is basically synthetic cortisol is such high-dose compared to what your adrenal glands would make it automatically down, regulates your drain production of cortisol and its natural rhythms. coming off of prednisone with these issues will leave you feeling like you’d rather be dead and having to deal with those side effects. Doctors today can’t even agree on adrenal fatigue so they don’t take even a minute to consider if a person needs prednisone or adrenal support in order to support their own natural cortisol production.

[@sharon12223]

The video is very helpful. Thank you.

[@martint4629]

Truly Excellent Video. Few seem to realise the difference between Blood Half Life, Tissue Life - plus the implications of P's longer duration of effect on Cells, Genes & Metabolism. (Kudos to you for clarifying this).As you point out, just because 5.5 Blood Half-Lives have elapsed, does not mean that P's effects on biology have ceased (far from it). I was also intrigued (and very appreciative) to learn - from one of your other videos - that as little as 2.5mg (maybe even less) could suppress the immune system. As you've previously alluded to - the implications for possible greater risk of Cov*id Severity (especially in the first week of Cov*id symptoms, when maximum immune function is highly desirable) is incredibly important for users to remain mindful of. I wonder what (if any) Meds / Preparations might (quickly) damp-down - or even reverse - P's changes to DNA / Genes? As Melatonin appears to be Cortisol's Polar Opposite, maybe that would help in this regard? I'm considering trying to switch to Mepolizumab, as that apparently dampens down eosinophils (which appear to be my personal respiratory nemesis). By the way, although P appears 'not' to have been proven helpful for Cov*id induced 'Anosmia', for me - taking x5mg of P for 7 Days - reverses (for about one month) my non-Cov*id chronic loss of smell / taste, thereby providing temporary relief from that awful affliction. Best Wishes from the UK.

[@PrednisonePharmacist]

Thank you! The nuances are important , right?

[@moviebuff6490]

I was misdiagnosed with a condition and have been taking Prednisone for 3 months, now I'm weaning myself off of it, currently on 2.5 ml for 5 days, then stepping down to 1ml for 5 days then I will be done with it...from the information in this video I'm supposing that the side effects will be gone within a few days after I quit?

[@lh5567]

When I have a bad attack of gout I take one high dose of 50mg tablet and it’s usually gone in 4hrs!!! Amazing! I don’t have to use it very often about maybe once every 6-7 months. If I feel it coming on I cut the tab in 1/2 and 25mg and it usually works. It’s been the best thing in the world for my gout!

[@tahiraejaz3008]

I am diagnosed with PMR almost three years and I want to know how long it takes to get rid from my body 🤔

[@bluesky7288]

Complex and fascinating. Thank you!

[@PrednisonePharmacist]

Glad you enjoyed it!

[@TheFunfairfan]

Oh wow love the analogy of a tornado . Fantastic video

[@PrednisonePharmacist]

Glad you enjoyed it

[@arlenecrespo4316]

Well explain, Thank you.

[@tommoso55]

Thank you so much Dr Megan, so informative. Tony from UK 🇬🇧

[@PrednisonePharmacist]

Glad it was helpful!

[@LarsDahlin]

I have been on a one year long cure, starting dose 30 mg, taken after a 20 mg Omeprazol. I do wonder if I have to step down the Omeprazol too... (Fun fact: The doctor wrote in my journal that I gained 30-40 kg instead of 3-4 kg. Got a good laugh together with the doctor when he found out that error. )

[@rollokline4692]

I am taking 5mg 2 times a day for long term and I can tell you its almost 16 hours

[@jennymatthews306]

Thats for the whole lot to be gone from your body - between 16hrs & 22/24hrs

[@ajaychauhan8161]

Thanks for very informative video

[@PrednisonePharmacist]

You’re welcome!

[@TheFunfairfan]

Have been on this 3 months due to severe ulcerative colitis , the moon face is horrendous . Have just taken my last 5mg as been on weaning dose . Do hope all this puffiness goes away

[@carolinebutterworth9788]

As someone with the same disease...yes, it does go away x

[@Emilyleestrong]

Did you experience any hair loss as the side effects after you tapered off from Prednisone?

[@carolinebutterworth9788]

@@Emilyleestrongyes, unfortunately 😔

[@inezreynolds1281]

Amazing and it can damage your mind

[@adarshvats5140]

Due to prednisolone i suffer from insomnia last 15 days today is my last does ! When will i sleep well?

[@PrednisonePharmacist]

Insomnia is awful, isn’t it? Here are some of my best tips to help you sleep: prednisonepharmacist.com/education/healthy-sleeping-habits/

[@rlynn5390]

So would a cortisol blocker help with weight loss?

[@PrednisonePharmacist]

I'm not sure what you mean by a cortisol blocker...

[@susanoff8577]

Thx Megan

[@PrednisonePharmacist]

You're welcome!

[@user-xi8jh8xo4b]

Been taking this devil drug for a month started off 60mg. After a week my legs, hands and face retaining lots of water i hate this drug so bad. Im tampering down to 10mg its been a week now im still swollen. I hate the fact i cant workout or do alot of the normal things i use to do. Maybe its other medicine too and my chemotherapy is making me feel like crap. I have heart failure and kidney failure ever since i had covid pneumonia 2021 my health started to decline.

[@82easyrider]

It's not devil drug. Please don't fall for a scaremongering. It's a lifesaver for a lot of patients. Just exercise extreme caution and avoid it when you can't.

[@frankbudd4625]

If you took any of the COVID shots you need to detox your body with the Dr McCullough protocol. Also get on Dr Mercolas newsletter for great health info.

[@mssoulsister2186]

I was given this medicine for ear inflammation and im having really bad hot flashes is this normal? It's 4mg 6 day regimen. I also feel very tired.

[@PrednisonePharmacist]

Hi, check out this article "Prednisone Side Effects - The Ultimate List" Read & watch here: prednisonepharmacist.com/side-effects-solutions/prednisone-side-effects/ For more information about prednisone, we have a bunch of content and articles that might be of help in your condition. You can browse our website at Prednisonepharmacist.com and discover ways to manage and counteract the side effects of prednisone.

[@Unek0777]

How long does the anxiety that can come from taking this drug last?

[@user-hs5hg2lp5e]

Following I want to know that too the ER doctors put me on this drug and my anxiety has been so high

[@calila650]

@@user-hs5hg2lp5e me too. I only took it for 4 days, just 10mg per day. I feel extreme heart palpitations and anxiety off and on, have had to take xanax

[@PrednisonePharmacist]

Hi! You can read this blog that I made regarding moods on prednisone. prednisonepharmacist.com/education/ways-to-cope-prednisone-mood-swings/

[@Unek0777]

@@user-hs5hg2lp5e It’s terrible. My ENT prescribed me this drug. She told me that it could cause mood swings or insomnia but she NEVER mentioned the psychological effects. I went from a person who NEVER had panic attacks nor anxiety to someone who has been struggling with anxiety daily throughout the day for the past 6 months. I’m so tired 😩

[@Unek0777]

@@PrednisonePharmacist Is psychosis or anxiety from this drug permanent?

[@abanaysadventures3098]

Steroids cannot be removed from the system and still impact it negatively for 10- 15 years

[@PrednisonePharmacist]

You can check out the whole article of this video that might be of help in your condition. View the full article here: prednisonepharmacist.com/education/how-long-does-prednisone-stay-in-your-system/ For more information about prednisone, we have a bunch of content and articles that might be of help in your condition. You can browse our website at Prednisonepharmacist.com and discover ways to manage and counteract the side effects of prednisone.

[@Shariiibabyyy]

I take 5mg everyday from a double lung transplant. The weight gain is horrible

[@PrednisonePharmacist]

It sure is! Weight gain is definitely one of the most horrible side effects of prednisone.

[@keithduffield5239]

Hi, watching your videos I am unsure if you for against Prednisone

[@PrednisonePharmacist]

Hi! Prednisone is a miracle drug that save lives, but most aren't aware of the side effects it can cause. Not against but just wanna give information that can help with the journey of every prednisone warriors out there 👋

[@GamerGuy1985]

You are gorgeous

[@PrednisonePharmacist]

Gee thanks! 😊

[@82easyrider]

I understand the importance of such information and respect your good intentions but your channel seems to send a lot of negative signals. We cannot forget many people take prednisone because that's the only choice they have. I've been a pharma researcher, I've spoken to 100s of patients, doctors and pharmacists for my research- and on this topic, I have noticed people face adverse reactions if its prescribed for a really long, long period in high doses, or when administered without any precautions. Scare mongering cannot help. People who take preds as per their cortisol spikes, with necessary diet and supplementary support alongside a positive mindset on a reasonable dose and period RARELY show serious side effects. While some of the effects may persist once the course is done, we are once again spreading paranoia, healthy individual's too system retain a lot of toxins and heavy metals. Absolutely no point in worrying about it.

[@glorialloyd1588]

Predisone is very cheap . I often wonder if this is why the negativity from doctors is the reasons they cant prescribe very expensive meds . Prednisone helps for sooo many things

[@PrednisonePharmacist]

Thanks for the feedback! I try to balance the message that prednisone is a MIRACLE with how miserable it can make us. I personally would probably not be alive without it. I appreciate your ideas of how to prevent it being a miserable experience. But statistically 70% of people gain weight. The majority of people reported in studies do suffer side effects. While doctors may categorize these as “not serious”, they are indeed life-altering. I’d love to have you on the channel to hear your perspective and have a healthy debate about this! Reach out to me at prednisonepharmacist.com/contact-us/

[@PrednisonePharmacist]

Also, despite the bias that side effects only happen later in treatment, many happen after just one dose.

[@user-sd5cm9wf6p]

I really don’t think she is fear mongering. She is informing people. Too many doctors, pharma workers, and medical so called experts, assume people are too stupid to think for themselves. I greatly appreciate these videos and information. I will continue learning and making my own choices.

[@tamara4676]

I'm sorry but I strongly disagree with you, I never read the leaflet before starting prednison (I have a medical background and had the same opinion as you have now) and I when I started to experience AEs, I was told by several physicians and pharmacists that they were suprised to hear that I had so many symptoms. It wasn't until I found Dr Megan's page that I knew I wasn't "special" or "crazy". I can only assume that you haven't been on prednison for a long time or several short periods, otherwise you would know what the impact is. Please educate yourselves before commenting on Dr Megan's page, someone who has the professional and personal experience of prednison.