How to Avoid Implantation Failure During IVF with Dr. Geoffrey Sher

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Dr. Geoffrey Sher is joining me again, and this time we are going to talk about implantation failure. Dr. Sher is co-founder of Sher Fertility Solutions (SFS) and an internationally renowned expert in the field of assisted reproductive technology, and influential in the births of more than 17,000 IVF babies. Over the last 30 years, he has helped fashion the entire field of ART after training under the fathers of IVF, Dr. Patrick Steptoe and Robert Edwards. He established the first private IVF program in the United States in 1982, then later expanded his practice to include several centers throughout California before founding the first Sher Fertility Solutions in Las Vegas. He’s also the author of several books, In Vitro Fertilization: The ART of Making Babies, which is now in its third edition.
In this episode, we're talking about implantation failure. Dr. Sher is discussing the role of the endometrium, the difference between implantation and miscarriage, and the three factors he considers when advising on treatment for implantation failure. The three things that he discusses are: lining thickness, texture and immune factors.
Thank you for joining me, Dr. Sher!
You can find Dr. Sher at his website, here:
www.sherfertilitysolutions.com/
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Watch the my other conversations with Dr. Sher:
Treating Endometriosis-Related Infertility: • Treating Endometriosis...
What is IUI? • What is IUI? History o...
Best Ovarian Stimulation Protocols for IVF: • Best Ovarian Stimulati...
Why You Need to do PGT (or do you?): • Why You Need to do PGT...
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Dr. Aimee Eyvazzadeh is one of America’s most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

[@a_l_e_k_sandra]

This is a kind of doctor that needs to be the most respected. Straight forward, no bulshit, no political correctness, just scientific facts and decades of experience. Thank you both.

[@elizabethh988]

Amen, he's amazing!!!

[@noraia2111]

Such an indepth discussion. Thank you so much. Please bring him back on your channel. He's so reassuring and knowledgeable. Plus she's a good interviewer - she allowed him speak uninterrupted.

[@donitta118]

“At the end of day, humans don’t create life”. 👏

[@atimnile2401]

1000% true; every life out there was A miracle 🙏🏿🙏🏿

[@MrsN78]

100% agreed 👍. God uses Dr in all these processes 🙏🙏🙏🙏

[@harrisclarina]

Facts

[@giftofthewild6665]

Thanks for going into detail about some of the factors affecting implantation! Not many videos or articles go into detail about this, its fascinating 😊

[@bibz845]

I could listen to him speak all day. Thank you both for sharing your knowledge with us ❤️

[@Toyinaroundwithlife]

Absolutely brilliant and beautifully explained! Thank you.

[@EggWhisperer]

You're very welcome!

[@CaraLudick]

How wonderful to hear a South African. Thank you for this!

[@EggWhisperer]

Glad you enjoyed it!

[@josephine2756]

Most informative - thank you

[@annie8995]

Thanks for all the great info!

[@EggWhisperer]

Our pleasure!

[@ssharb760]

Thank you so much for this! May i ask where is the link for the book he mentioned?

[@stephaniewong7152]

I wished they had doctors like him in Canada.

[@madeleinealvarado4162]

good to know about the endometrium lining. I went today for my check up endo thickness and they say it was 8mm. They say it was good enough. Same as your answer. I did have a polyp and it was removed.

[@Chifum8967]

Thanks for the helpful information. Please What do you do if your endometrium started become thick before implantation? Up to 20mm

[@fatimabuhari7251]

is there a summary of this?

[@adetouna5836]

I couldn’t download the book. Please can you reconfirm the website

[@srhod3908]

Would bleeding issues/disorders be linked to implantation issues?

[@feelimpianist]

no one talked about blood circulation. Just found out from nls biofeedback that reproductive system cannot absorb nutritions for follicles and transplant. Need to work on circulation.

[@kuroe-chan5190]

I wish PGTA testing was semi covered by insurances. My insurance covers up to 6 egg retrivals in a lifetime but no genetic testing coverage. If they did that tho I do beleive their wouldn’t be more successful IVF cycles but a good majority can not shell out 4-10k extra after everything else and have to take the gamble having a unviable embryo :( of course I’ve know women as well who had perfectly healthy embryos but pregnancy still didn’t take. Finally in her 3rd IVF it did. So so happy for her

[@iseaglewings4031]

Many peoples insurance in the US, like my own, dont cover a dime of IVF or any fertility treatment. I paid out of pocket for 3 IUIs, blood work related to fertility, all fertility medicines, and now for a IVF stuff.

[@psychiatrist123]

Can we start letrozole on the 3rd day of progesterone widrawal bleeding to prepare for iUI after being on progestin only pill for 3 months without periods for 3 months ? Or should we skip withdrawal bleeding and wait nor natural menses to start letrozole?

[@maloupascua503]

I had my embryo transfer 2 weeks ago in Cebu Philippines and when I had my beta HCG it turned out negative. I cried a lot because i put too much effort, time. I'm not that rich to have it again. Iwant to do it again but Im financially drained out. So depressed, I cried all night, I could not sleep. I dont want to eat. I am compliance with my medication, im careful with my diet but my embryo transfer was not successful.

[@m.d.j174]

Just like the doctor said, humans don't give life. God does. He don't need the perfect situation to make a miracle. Bringing life unto the world is a miracle. I'm trusting God for a successful transfer in a few months. My hope is in the lord. I've done what I can do on my part. I wish you all the best. Just like my doctor said, if it's a baby you want and you are persistent, you will have a baby don't give up. There's options out there like embryo donations. Be bless!

[@Eli-bz4vv]

@@m.d.j174so beautiful what you said.

[@maryalbertoes9208]

Hi doc..can someone repeat ivf with frozen... embryo and the same failed first time...

[@rebeccachesbro3251]

I have scaring from a ruptured appendix.. per Dr my scaring is small shouldn't hold pregnancy back... However everytime I get pregnant and now with IVf I feel my uterus get hard like a tennis ball and then I lose the pregnancy

[@anjaliadhikari4673]

Dr Amee when you all say uterus is not receiptive than one question comes in my mind why would the embryo implant in the fallopian tube? Is that receptive? 😊despite of not having the component which a uterus has embryo gets implanted in tube is so unbelievable.

I just had my second failed implantation. I am cursed with having both endometriosis and a small fibroid inside my uterus that can't be removed. I guess I ha e my answers. I am using donor eggs of a 24 year old. The embryos always look amazing. But I keep getting flat out negatives. I am devastated. My heart is so broken. Getting that news on Friday, Mother's Day weekend, if I wasn't strong, I wouldn't be here today. I am 39 with an extensive Endometriosis issue. I've had multiple surgeries.

[@christineo7930]

That’s heartbeaking, so sorry! Wishing you a baby miracle ❤️.

[@anjaliadhikari4673]

That’s heart breaking i send message to our god shiva to give you a wonderful baby. Good luck and try again. Best wishes to you.

[@Loralou4455]

So sorry to hear that sis, praying for God to turn around ur story ❤️

[@hellenmuka7207]

I just had by bad news today...my specialist implanted 3 embryos at once and none of them stuck....I'm so devastated...I'm 35

@@hellenmuka7207 I am so sorry 😞

[@anniaeti7322]

Correct

[@jonathancarter4128]

Hi doctor, does injecting ivf intramuscular medications on the buttock cheek rather than the hip cause an unsuccessful ivf cycle?

[@kuroe-chan5190]

Hm most ladies i knew 3 actually injected the progesterone in their buttocks, and each one. Had successful IVF the other medication they did in lower abdomen. Didn’t know you could do hip

[@Eli-bz4vv]

I had a miscarriage with my first transfer. And the second embryo didn’t stick with a lining of almost 10. Now the doctor want to do a ERA and fallow with the next transfer. But we dived to do another retrieval because I just turned 40. I was 38 when I did the first retrieval. How could we loose normal PGA tested embryos?

[@flipflopsandbutterflies7673]

This was a really interesting interview but just to let people know, the ebook Dr Sher mentions is free to download actually isn’t - when you look for it on his website it states that once you book a consultation with one of the doctors they will send you the ebook after the consultation. I appreciate all of Dr Sher’s insight however it is misleading to say the ebook is free to download when it isn’t.

[@DMS1985]

I just downloaded the book! It’s 170 pages

[@fanstab5698]

What are the immune system illness known as a cause for infertility?

[@kuroe-chan5190]

I do beleive rheumatoid arthritis is one. I was diagnosed in 2021. Internal inflammation is hard and I feel that has been some of my problem. We’ve been trying 15 yrs with no real answer. I say sub fertile for both me and husband and I. Now I’ve lost 200 lbs and have my inflammation under control and still no pregnancy :( starting to think I’m unexplained

[@fabitoscano8692]

Hmmm. This Dr. Has pretty bad reviews on Google. I found his videos to be very helpful bout after reading the reviews I’m doubting 😳

[@elizabethh988]

He's truly phenomenal and does get amazing results!!!

[@Ifyjames]

Thickness, normally and immunology of the womb

[@angellee5635]

Would fibroid reduce the chances of implantation?

[@jtabal100]

Possibly

[@paintingartist2251]

Hi, doc, I have been on a long infertility journey for almost 11 years with 3 failed IVFs, which my fertility experts narrowed down to poor-quality eggs as none of the eggs matured after pickup. I had OHSS with all three, I went in for the 4th cycle and they picked up 23eggs at 40hours and with months of DHEA 50mg for 4 months( the only solution they came up with) and I have now one 1 embryo which is now frozen(they didn't tell me the quality and being scared I never asked. Currently, I am dealing with OHSS again. What would you suggest before embryo transfer? Should I take something? And is transfer fine after 3 menstrual cycles? Please help...My recent AMH was 1.3

[@krystabell675]

Why DHEA?

[@paintingartist2251]

For egg quality improving, but didn't work significantly..

[@Shnug946]

Did you do CoQ10 and Vitamin D at least?

[@giftofthewild6665]

DHEA is for low ovarian reserve. With your numbers it seems you don't have that issue (low reserve women typically don't get OHSS either since there are so few follicles). For low quality without quantity issues you should focus on acai, co enzyme q10, good prenatal vitamin, folate and healthy diet & lifestyle (organic food and remove plastic & Teflon products from your kitchen)

[@paintingartist2251]

​@@giftofthewild6665thank you for the advice, I haven't been prescribed any prenatal, I definitely start.. FIP my embryo transfer failed, clinic couldn't give any reason.