How to make Nitrobenzene

Nilered back in the day: sophisticated chemistry Nilered these days: Gold grillz

[@NoNameAtAll2]

academic vs commercial chemestry

[@kevinbyrne4538]

Many thanks for taking the time and trouble to research these experiments, perform the syntheses, film them, script them, prepare the graphics, edit the videos, and upload them. A lot of work. Your efforts ARE appreciated.

[@TheFlipside]

1:30- I laughed pretty hard at this part cuz I remember doing nitration of nitrobenzene as a lab during my first semester of organic chemistry. The lab book even had a warning in bold and all caps that said to keep the solution between 60 and 70 C during the addition, and if it goes above 70, to shout "leave the area immediately"

[@sheevpalpetine7687]

Welp, its pretty close to TnT, the recipe is nearly identical, if I remember correctly...

[@TheFlipside]

@@sheevpalpetine7687 yep! All it needs is another meta nitration and adding a methyl group on there somewhere

[@sheevpalpetine7687]

@@TheFlipside Nornally you just Start with toluene, no need for the addition of another group. Makes things a lot easier...

[@TheFlipside]

@@sheevpalpetine7687 oh for sure, especially how deactivated a tri nitrated benzene would be. I was just assuming in this scenario you'd be already starting with nitrobenzene

[@andersjjensen]

@@NerdyNEET Of all the stupid ways one could deal with an over-nitrated volatile substance, that method is most certainly on the less-stupid end of the spectrum...

[@mr.unknown1070]

Now this is where I felt that drawing hexagons on my notebook pages actually helps to understand the video 💀

[@Kyoobur9000]

*Nitric acid:* I’m hydrogen nitrate *Sulfuric acid:* Nuh-uh you’re nitronium hydroxide

[@user-pr6ed3ri2k]

imagine nitronium sulfate

[@Kyoobur9000]

@@user-pr6ed3ri2k I did, it burned my imagination.

[@Dude8718]

Saying you're doing chemistry from erowid prolly puts you on some sort of watch list

[@georgebritten8208]

Not at all! Many of the reactions found on it are referenced too, by the authots from scientific journals and academia. Not all of it is direct drug synthesis either nitrobenzene isnt illegal where I'm from nor is it's synthesis

[@DIGITALVHS]

I nearly did a spit take, I was just like what's next? Maybe some chemistry from The Hive

[@jhyland87]

@@DIGITALVHS The Hive had some great chemistry! (Now it's just an archive, but still good stuff).

[@DIGITALVHS]

@@jhyland87 i love those archives, there's some really neat procedures on there. My favorite has to be the performic acid oxidation of isosafrole to mdp2p. Suuuper neat chemistry there

[@Aztesticals]

@@jhyland87 I always like isomerization of cbd oil into delta 8 and delta 9 thc and then steriospecific isolation of delta 8.

[@sweetyd.8914]

I was learning preparation of nitro benzene & I searched a video regarding it & I saw Ur video sir , whole topic got clarified..thank you so much sir for crystal clear explaination

[@vincedibona4687]

*you’re

[@mr.unknown1070]

Add H2SO4 to the benzene first, so that sulphonation can take place and then add it to HNO3 with some extra H2SO4 for NO2+ electrophile generation. Keep benzene in high amounts so that we can reduce the chances of multiple nitrations. I remember this method from my textbook for making picric acid. It gives a pretty good yield

[@MrHughesNZ]

brilliant video, professionally presented and great for students to learn from. thanks for making these!

[@vincedibona4687]

Nowadays: G O L D G R I L L Z

[@NormReitzel]

One of the reasons one can get a low yield from this reaction is the entrainment of nitrated product by calcium chloride. I think you can get a better yield if you a) use only about 1g of calcium chloride, an b) dry the crude product before distillation. A side note, this was the very first organic reaction I attempted in high school, in 1969.

[@jonathanleitch6176]

Norman Reitzel dude. I’m a chem teacher and we teach this mechanism, as well as the reduction of nitrobenzene to phenylamine to the IB Chem HL course but by today’s safety standards none of this is even remotely legal. I wish it was 50 years ago haha.

[@spiderjuice9874]

What are your thoughts on adding the chilled mixed acids via a dropping funnel into chilled benzene? Maintaining benzene in excess should prevent any formation of multinitrated products, and if benzene is in a molar excess then separation of benzene and nitrobenzene should be eqasy and safe.

[@abhaythakur1244]

Firstly... Damn man you are so awesome, the way how you explained everything was so fantastic. Secondly.. Thank you so much you helped me in making my assignment 🙂 Lots of love to you bro

[@jeffhurckes190]

I'd be interested in seeing the making of Sodium dithiophosphate, a chemical used in ore flotation.

[@196Stefan2]

You probably don't need to be concerned about the formation of 1,3-dinitrobenzene and 1,3,5-trinitrobenzene. They require harder conditions, at least fuming nitric acid instead the 65% HNO3, and a longer reaction time.

[@elephystry]

196Stefan2 well, if you heated it enough, the concentration of the nitric acid would probably increase

[@Script_Mak3r]

Concentrated nitric acid is already azeotropic, so the heat would mean that acid was going into the air, rather than becoming more concentrated.

[@pietrotettamanti7239]

196Stefan2 traces of the dinitrobenzene can easily form.

[@MrCcfly]

so it will be mistake to use let say 90% hno3 and leave all that cook on 2-3h over 150c ? we did that on one experiment and all was same like in this test ,and we only use distil water ,room temp to cool it down under 200c ,so how is possible to get di let alone tri by longer reaction i dont get it

[@trent6319]

I think the reaction would be easier with toluene or xylene as the methyl is an activating group, but then your literally making tnt

[@amogh3195]

This proved extremely helpful for student during online classes who could not go to lab

[@andreiprecup99]

Fun fact.In school i was taught that nitrobenzene also called Mirbane Essence was used back in the day in soaps ,because it smells like almonds (bitter almonds to be specific)

[@PartVIII]

rhodium is the bees knees

[@someweirdkid8584]

Im late but I read that as "the knees bees"

[@DIGITALVHS]

And boy do the bees love it too

[@allen.simmons9150]

haha bees. the fact that only some people will get this isnt just a 50s joke is funny

[@abdulwasaywaseem4147]

Respect all the way from Pakistan!!!! Perfectly demonstrated🔥

[@pete8420]

I clicked on this video because I saw the title and went "ooOOoo that sounds dangerous and possibly illegal"

[@piranha031091]

Why don't you add the calcium chloride before the distillation? That way you wouldn't need to filter it off.

[@pratishthabajracharya7]

This helped me remember the reactions for my exams 🖤

[@tylaney8537]

off topic, but can you do a video(s) talking about the different distillation setups i.e. fractional, vacuum, steam, soxhlet and any others there might be. What one would be best for a beginner etc. Please and thank you, that is :)

[@catonchronic5354]

Simple distillation

[@RahulKumar-yy7hd]

पटना साइंस कॉलेज में मैं सबसे पहले इसी यौगिक को बनाया था इसमें ग्रुप में हम लोग दो बंदे थे और इसको बनाने के बाद इतनी खुशी हुई थी कि हमने ट्राई नाइट्रो बेंजीन( TNT) क्रिस्टल बना लिया। Exothermic reaction ( to obtained crystal put solution under cold tab water....)...most dangerous reaction....

[@natanieux]

I was looking for Vocaloid, didn't knew he had this video.

[@sunshine__707]

no I can't watch this without thinking about the vocaloid song

[@DFliyerz]

For once, I actually made a chemical BEFORE you made a video on it! Also, do you plan to do a video on the reduction of nitrobenzene to aniline? I've only seen one video on it before, and it required some pretty heavy-duty equipment.

[@elit3chemist958]

+DFliyerz i hope he make reduction video

[@NileRed]

+DFliyerz to be fair, it was filmed and edited over a month ago :p. I have already made the aniline and the phenylhydrazine and edited both :). The aniline will be posted in a day or 2

[@elit3chemist958]

+Nile Red woooow im waiting :D

[@nicholi8933]

I had a synthesis lab that I had to do a nitration to acetophenone. I ruined it by letting the nitroacetophenone solution go to about 10 degree celsius. It was terrible.

[@Bretcmm]

Would love to see you turn this into meta-bromoanisole...or for extra challenge- can you synthesize m-bromoanisole without using nitrobenzene as an intermediate?

[@RhetteLawe]

ehhh.... i think you'd be better off crystalizing your product out instead of distilling it. crystalization is much safer than distillation in this particular instance. Also... i'd use magnesium sulfate instead of calcium chloride.

[@TheRandomness707]

were you inspired by nurdrage by any chance to make chemistry videos?

[@NileRed]

+1337_Vid305 Actually, yes.

[@rogerprodactorstevez6740]

I think you are nurdrage low-key J s

[@rogerprodactorstevez6740]

Aug your voice all you want. But you can't shake those : "anyway....", "aaaaaaaand" , & your language is just identical. Luv you bro

[@Wheresmy240]

@@rogerprodactorstevez6740 I've thought the same thing before.

[@someweirdkid8584]

This is how you make nitroglycerin , just replace the benzene with glycerol Edit: and you don't have to distill and probably shouldn't.

[@TheGpsm]

Loved your video!

[@mickeymouse4095]

Damn, those junkies really know their chemistry !

[@tenaciousgirl5201]

i really love your videos

[@jurajkanik4095]

nitroglycerine ????Please making nitroglycerine.Your videos is very good.

[@chemlab9873]

Can you make a video on preparation of Bromobenzene

[@jhyland87]

NileRed doesn't seem to have a bromobenzene synth video, but here's one (which I'm sure you've seen, but just in case you haven't): kzbin.info/www/bejne/jX65pmCBiLWmeck P.S. I like your channel - Subscribed! ( _with_ notifications.. lol)

[@mrchangcooler]

Will you also create toluene, and it's explosive cousin Trinitrotoluene?

[@NileRed]

+Mr.chang cooler I might make toluene, but I dont think ill make TNT. If I did, it wouldnt be a tutorial. I dont want people blowing up :p

[@jtbmetaldesigns]

The waste water is always a problem with aromatic nitrations. Could you treat the waste water with potassium permanganate acidified with sulfuric acid? Would that be strong enough to open the aromatic ring with carbon dioxide and nitrogen oxides to be collected?

[@elit3chemist958]

great work that is awesome

[@MissYaminiPatel]

Very excellent sir

[@MrTarmonbarry]

Came here via a book written by ''Rex Stout '' called ''The red box ''. Murder mystery, this stuff was used to murder someone via skin absorption in the story

[@DYLANTRIES]

I have been using a very old bottle of gun cleaning solvent on my guns that contains nitrobenzene

[@guiltyeyesfever]

I was looking for the vocaloid song, how I ended up here

[@saraahmed9432]

الله يسلمك كلشي مفتهمت عدنه استاذ دزنه عليك الله يسلمك بس ولله الحمد ولا طكه فهمت🙂💔

[@hjoora2219]

متت😂😂

[@saraahmed9432]

@@hjoora2219 😂😂😂 الله محد خلص من عدنه حتى ع اليوتيوب صنفنه😂💔

[@hjoora2219]

@@saraahmed9432 اي بالله 😂😂💔🌚

[@jdflyback]

Is NaOH a suitable replacement for the CaCl2 as a drying agent?

[@elit3chemist958]

+jdflyback i think its not suitable in this exp bcz it cant react with water unlike mgso4 that react with water and form h2so4+mgo

[@gale9703]

Ain't no way my school used this video in the online lecture to learn about electrophilic substitution

[@rcsibiu]

I was hoping you will make a video where you create TNT but I can't find such a video on your channel

[@caelanomohundro-topic1473]

Okay, so this video is dead so I hope I get a response, but I ordered nitrobenzene, and it came in, and it’s in a powder form… what do I do to make it more like yours?

[@floridaboiash]

Thanks bro

[@CRU22]

Our professor made this video our orgo lab final assignment.

[@youssefmahmoodkhedr7231]

can you tell which to add first nitric acid or sulfuric acid in nitration of benzene and why ???? please

[@hayakhan5861]

how much time this experiment will take..?

[@mrmusulmon4610]

Is this reaction possible with pyrazinoic acid

[@qazsertyer]

What's the point of heating the solution when all the benzene is added?

[@NileRed]

+MarcCG Just because it is all added it doesn't mean the reaction is complete. To complete it, some heat is added (Which speeds things up).

[@qazsertyer]

+Nile Red Thank you for the response! Me and some friends are watching your videos, we are still undergraduate students in chemistry from Barcelona it's very useful to see the reactions in the lab. We hope that you keep doing videos! PD: Maybe I'll propose some reactions in the future. Do you still check out the video you made to make this suggestions?

[@JDeffenb]

Awesome

[@neald27]

how should the nitro benzene water washes be disposed of also when washing the glassware after this synthesis (and similar ones that use benzene) is there anything special that should be done due to the benzene present

[@NileRed]

+neald27 It should go into an aqueous waste container. What you do with it after that is questionable. Label it correctly and call someone to take away the waste when you have enough.

[@brianrigsby7900]

How exactly does one dry a liquid? That’s always confused me in his vids when he talks about drying liquids

[@chemlearner2721]

Dry= Remove the water portion of this water/other chemical mixture.

[@Создатель-з7ъ]

Just pour the liquid into the flask and pour in the calcium chloride. A period of a week should be enough to drain completely.

[@Izzy.rodfrz]

Does someone know me the chemical equation that represents the synthesis of nitrobenzene ?

[@demoaccount2392]

At what circumstances benzene will react to make nitrobenzene, dinitrobenzene and trinitrobenzene. ☺

[@necromaster998]

"Using a synthesis from erowid" Nice.

[@VipeRGamingCSGOviper]

whos here after a level prac

[@fen17072010]

Dead already. My whole set up is wrong

[@DevonHomeBrew]

i wish these were around when i did alevels, might not have failed so hard

[@karllauer4820]

whar kind of vacuum pump do you use for filtration?

[@twoduces195]

i know this is old but can a nitration be preformed 3 times to create tri nitro toulene and since the ch3 ion is a weak activator and directs to the ortho para position but with steric hidnerence wouldnt the para postion be the most favorable? and therefor both ortho and meta since no2 is a strong deactavor can be nitrated to create 2 4 6 trinotro toulene? or would it be to slow

[@Spruce-Bug]

How do you dispose of the wash water properly?

[@mohammadshahed110]

Hello. How to wash the dishes that contaminated with nitrobenzene?

[@masterlabLAB]

how can you measure the temperature during the nitration without a thermometer? like a magician?

[@hatimboy1]

masterlab LAB put your hand in it , if you scream its probably too hot , if you dont scream immediatly but after like 5-7 seconds , ure good to go

[@LiborTinka]

IR thermometer can be used to check flask temp quickly

[@truptibhavsar3281]

I liked this video

[@StrexTve]

INTERESANTE

[@olikaadzalia9129]

i have some questions. i have a final project in uni. the project is make an chemical industry paper. so i've choose nitrobenzene industry. i made it based on patent. In the patent that i used. it written that the reaction using mixed acid and benzene. but before all the feeds entering the reactor mixed acid should be heatedd around 80 degree celcius. and the condition reactor is about 135 degree celcius. and after the spent acid is romeve by dekanter and evaporate to use the recycle of sulfuric acid. the thing that i want to ask : 1. is it harmful if the temperature in reactor raise 135 degree celcius? 2. if the temperature raise above 50 degree celcius it will make dinitrobenzol. if so, why? we can separate it by separation appratus? 3. should nitrobenzene is being washed by the base solution? please help me.. thank u.

[@IntegralMan]

FIRST! Love your videos Nile Red!

[@aviral2511]

Please can you post a vidoe on how to make nitro glycerin using nitrating acid mixture and glycerin.....

[@tek4]

Spark Chemistry this is a very dangerous exothermic reaction that produces some unstable stuff...

[@HipHop-pc1sq]

How to make pure nirtomethene..at home plzzzz tell me😥😥😥😥

[@aquitasb9096]

das würdest du gerne wissen =D

[@hatimboy1]

can anyone tell me how you got to those amounts of ml's in theory ? everywhere i see people using diffrent ml's for diffrent amounts but no one states the theory behind it :s

[@Timothy656]

Read up on stoichiometry and balancing chemical equations as that will answer most of your questions. Some people use a slight excess of one reagent in a chemical synthesis because it helps drive the reaction to completion or practically the reaction just works better with one reagent in a slight excess (trial and error). Thats probably why you see people using different amounts :)

[@dbug7276]

Beautiful flowers made by Samsung galaxy 😍 ✨️ 💕 💛 ❤️ 👌 😍 ✨️ 💕 💛 ❤️

[@shishkumar6042]

1:44 why was heating necessary?

[@Создатель-з7ъ]

Reduce the yield of m-dinitrobenzene

[@alllove1754]

Hi! I have a a request: please make the substance for a semiconductor diode and, specifically, demonstrate for the world how one positive and negatively DOPES it. Im strongly interested in hugh spectrum LDs and have confidence in you. I don't mean read a book or draw it (thats what i do☺️) i mean SHOW A mofo, PUHLEASE😇

[@moonlacis]

this video is 7 years old ma'am 🤣😅

[@alllove1754]

@@moonlacis yes it is.. i think i sent that request out to every chemistry channel i was subscribed to amd had faith in, as in faith in each's abilities. Maybe a commentor would do it? I would, IF i could get my hands on lab equipment. I want to do some real exploratory stuff with semiconductors and LEDs i don't believe we are far behind the general public making morw advanced stuff than even Wright-Patterson has seen😇🥰🤩😍(x)🤩🥰😇

[@nextgenerationjkd2150]

this class fine

[@IriathZhul]

Looks like lime cordial.

[@tianar1986]

thankyou thankyou thankyou

[@Hello_Friends]

Azeotropic means

[@lukegaming86]

My guy using synthesis notes from erowid 🤔

[@steph1660]

bro made rin sound like a car horn!!! wait wrong vid

[@SansOverlaurd]

Make nitroglycerin

[@Shyguy71588]

Why did he get such a low yield?

[@OmPrakash-pc1ec]

probably because polynitration

[@djsmileyoflasvegas]

what is nitrobenzene used for

[@keithqueen4434]

+djsmileyoflasvegas it can be reduced to synthesize aniline.

[@elit3chemist958]

+djsmileyoflasvegas can be reduced to aniline then forming diazonium salt that undergo many important reaction(u can search in google reaction of diazonium salt)

[@keithqueen4434]

+ELiT3 CH3MIST that diazoniom ion.. Such a useful tool. One of my favorite reagents.

[@djsmileyoflasvegas]

+ELiT3 CH3MIST thanks for the responses was curious about this

[@elit3chemist958]

+djsmileyoflasvegas u r welcome bro

[@akiraakiraakiraakira]

there are some moments in this video where my buttcheeks clenched

[@douglasboyle6544]

God damned yellow chemistry.

[@416d6f6e]

*sees nitrobenzene instant gregtech ptsd (its gas turbine fuel in gt) (i played too much gregtech)

[@mrfat2354]

hahahahahhaha same

[@juketu982]

@@mrfat2354 halts maul

[@karolus28]

cool

[@BiscuitGirl9154]

Can u make methamphetamine plz

[@iosef3337]

If you look at its molecular structure and still dont know how, then you need study more.

[@chefinwhitecoat]

Yellow chem bad!

[@egorkamedic]

hello im from Russia help me please , ,My nitrobenzene surface on the water in separating funnel after reaction. i made its synthesis 4 times

[@Создатель-з7ъ]

Поподробнее.

[@egorkamedic]

@@Создатель-з7ъ я получал от нитробензол, им хорошо пахло но по окончании реакции и разделении продукта у меня никак не хотел образовываться слой нитробензола и образовывался водный раствор жёлтого цвета с примесью всего сколько раз не переделывал и температура точная как в методике и все условие я кислоты конц

[@Создатель-з7ъ]

@@egorkamedic Серная и азотная каких концентраций были? Лично у меня с серной 98% и азотной 69% все вышло на ура.

[@egorkamedic]

@@Создатель-з7ъ 65 азотка и серкк 70

[@Создатель-з7ъ]

@@egorkamedic А как жидкости в изначальной смеси распредилились? У меня вверху был нитробензол, внизу - серная. В дальнейшем, когда промывал, нитробензол был только внизу.

[@thatoneguy454c]

trinitrotoaniline is what real men aim for lol

[@MrKittke]

what is the fuming at 2:05 ???

[@T4.Bacteriophage]

i dont see any fumes

[@ProjektOchExperiment]

+MrKittke I would assume that's from the Nitric acid that is present in the nitrating mixture. Might also be from the H2SO4.

[@MrKittke]

ok :) thanks

[@ProjektOchExperiment]

+MrKittke No problem! :D

[@masonrodrigues76]

How do you make trinitrobenzene? like if you want this

[@MrCcfly]

easy you go to shop give $ and permit and u get how much u want

[@fabrizio816]

kittemurt

[@tv-pp]

hhmmmm.... i wonder what erowid would do with nitrobenzene...

[@TonyMontana-wo5rz]

Heisenbergs blue sky

[@vincedibona4687]

@3:21 - W O R L D C L A S S T A R

[@huanzhengphung2534]

greg

[@Johnmiccael1]

Erowid.... Swim right?