Insulin Resistance and Metabolic Syndrome with Dr. Ben Bikman

The title for today is focusing on Insulin Resistance in the Metabolic Syndrome, and I could describe that another way, which is just kind of understanding metabolic health and that’s at the heart of what I wanted to focus on for the time that we have during the lesson itself.
Alright, so first of all, metabolic health. We’ve all heard the term metabolism a lot. It is a buzzword, it is a word that we hear perhaps too often and even to the point that it’s often misused.
Metabolism, just to be very precise, is the balance of all of the chemical reactions that are happening in the body. There are biochemical reactions in every cell that are trying to build up molecules. Those are called anabolic reactions or anabolism, and there are chemical biochemical processes that are degrading molecules, breaking them down. That is catabolism and metabolism is the fusion or the balance of all of those things. The sum of all of those reactions.
Now with metabolic health, we’re starting to get more specific to the topic.
Learn more at: www.insuliniq.com
#insulinresistance #metabolicsyndrome #metabolichealth #type2diabetes #type1diabetes #weightloss #intermittentfasting #intermittantfasting #fasting

[@Eclecticladylove]

I wish the videos had as part of their title the order in which you should watch them (like unit 1 unit 2 unit 3 etc.) because when you start to watch one you will often hear him say you should watch all the previous ones first but you can't tell from the Title which one is first, second, etc.

[@renukadevgharemore7183]

Totally agree

[@rogmo46]

Totally agree!

[@letlovedesign3088]

I don’t know if this is helpful, but the thumbnail picture on each video has an episode number.

[@annettestephens5337]

Ben Bickman is brilliant at this stuff

[@insuliniq]

Thanks for your kind comment, Annette.

[@CrumbleLives]

There isn’t a thumb’s up button big enough to acknowledge my gratitude in you sharing your knowledge.

[@adililyas4195]

Thank you so much for putting the concept so perfectly. I am a 40 year old Pediatrician. I have been following low carb lifestyle since last 5 years and it has completely changed my life. But i have been really struggling to convince my loved ones and colleagues to do the same, as you know the common belief is completely different. I feel like i am swimming in a river against the current. But since i started following your videos i finally feel like now i have the words and correct knowledge to be able to convince others. You are doing such a great job, i wish i had the honour and privilege to work with you. Keep up the great work👍

[@insuliniq]

Thanks for your comment. You may want to consider working with us through our Insulin IQ Certified Coaches program: www.insuliniq.com/master-course-become-an-insuliniq-certified-coach

[@yoso585]

Metabolically health people need not fear the carb. It is those of us that have abused ourselves that have issues. Just something to remember.

[@adililyas4195]

@@insuliniq this sounds great, i would love to register for this

[@insuliniq]

Thanks for joining our team this week.

[@adililyas4195]

Believe me, the pleasure is mine ☺️

[@jamesatkinson5805]

Great info, i randomly was listening to a Cardiologist give a lecture last night and i'm going blank on his name but he was going over the same point that you did at the end and it makes so much sense, that insulin will keep going up to manage glucose until it can't anymore, well it makes perfect sense that insulin should be the thing people should be checking on

[@johnburton9772]

Excelleent, Dr. Bikman! I wish this would have been known and communicated to doctors and patients 25 years ago! I'll buy your book and watch your future podcasts. Thank you!

[@insuliniq]

You’re kind. Thank you.

[@roxanneben1222]

I lost 63Lbs doing carnivore. Decided to add back some carbs, salad, veg. In three months I gained 15 Lbs. looking to get a CGM, to figure out what my body can’t handle.

[@slay2525]

Drop the cannoli, take the salad.

[@tickermum385]

Thank you Dr Bikman. ! You are the best!

[@SCM1949]

Thank you so much Dr. Bikman for an excellent video‼️I look forward to all your videos. Stay safe & well❣️

[@dcnike820]

Wonderful clarity. Brilliant.

[@dahof2789]

Thank You Dr. Bikman! You influence more lives than you might think. I'm at old IT guy who tries to keep up and you do a great job of describing complex topics for non-scientific minds.

[@rubiccube8953]

Your knowledge is much appreciated. Which I apply to great effect. Thanks.

[@pramujisinggihriyanto6901]

Thanks, Ben. You are real expert on this topic. Awesome n clear-cut as crystal your explanation on insulin resistance syndrom.

[@insuliniq]

Thank you for watching and commenting.

[@melao29]

Thank you for sharing your knowledge with us! I have been listening to podcasts you have been featured on and I love your insight and expertise.

[@lzaffke]

Great video. I look forward to more videos.

[@renukadevgharemore7183]

So happy to see metabolic classroom again. It's really lots of learning.

[@tallcedars2310]

Great lesson. It's presented in layman's terms that are easy to follow. This is very much appreciated and I look forward to watching the following lesson.

[@TheRealDoctorNelson]

Thank you very much Dr Bikman, great lecture!

[@simonwiltshire7089]

Fantastic post. Read the book (bought on audible first then bought the book!). This just makes complete sense to me. Thank you Ben

[@dahirb]

Excellent lessen to learn which will help any one who need to learn health is a useful resource and will benefit thank you too much

[@user-bk5oi9wg7e]

Thank you Ben, I really love your videos and find you so helpful!

[@24bellers20]

Excellent one Ben. Shared far and wide.

[@insuliniq]

Thanks for sharing!

[@user-rp1nd5go8g]

Excellent lesson!

[@dr.ashabenakappa354]

We love you loads dearest DrBen

[@insuliniq]

You’re kind. Thank you.

[@indialukeluke690]

Always you present great information

[@joanl9383]

Excellent and thank you!

[@sandiebrown9521]

I have type 2 diabetes and my doctors have always maintained that if my medication stops working then ultimately I will need to be put onto insulin injections. As a retired animal technician who worked with transgenic mice specifically in molecular pharmacology and the P4503A1 gene, I am no stranger to the term insulin resistance. I never understood the logic of prescribing insulin to a person who is insulin resistant 🤔

[@zaidizakaria8272]

Thank you so much Dr Ben... 👍👍👍From Malaysia

[@CalmCowBell]

BEST thumbnail EVER!

[@Mary-zi5jm]

Knowledge worth in gold

[@dustyarcher]

Absolute legend 💕💕💕it

[@gregferguson2170]

Thanx for a great video. Love learning about this.

[@insuliniq]

Thanks for watching. Kind of you to comment.

[@H4KnSL4K]

Thank you, Sensei!

[@insuliniq]

My pleasure!

[@pilgrimlady8196]

Thank you!

[@kristinevans283]

Love this Dr Bikman. I teach about this and you in my dental presentations I give. I am the pHRDH and would love to meet you someday and collaborate. You are changing lives and I am encouraging people to follow you and help educate patients about oral-systemic health.

[@insuliniq]

Thanks, Kristine, for your kind comment.

[@MrWoodward42]

Great Talk. Would you please consider creating an accompanying slide deck or some sort of visual aids? Thanks.

[@shirleypeterson6393]

😮 Excellent Excellent!

[@Happymomto9]

I’ve been wanting to just pop into one of your classes at BYU (my daughter is currently a student) so I’m glad to have found your channel!!

[@insuliniq]

Wonderful!

[@candyrakrelnikov3015]

Thank you!!

[@mrsboogybren2657]

Thank you for the great videos. Can insulin resistance impact the function of the vocal cords, please?

[@t.p.7373]

Thank you

[@venkataponnaganti]

Very illuminating

[@insuliniq]

Thanks for watching and commenting.

[@yolandaoleary3832]

I'm doing carnivore, have hx of type 2 was on actos, metformin, insulin pump, trulicity, and statins etc. Fasting insulin is 15.9, A1c 8.5. Triglycerides going up. Always BS in 200's and 300's even on all those and low carb. Took myself off actos, pump, after reading all side effects of each. On Metropolol, Ezetimide, Amlodapine, Rouvastatin, Olmesartin for HTN. Doing carnivore/keto since January 2024 and trying fasting everyday with at least 10-14 hours. BS continue to be in 200-300 range while fasting. Question, how to get BS down, should I take rapid insulin shots? Dr. Berry said to go back to metformin-no differences in BS's. Your videos are astounding and the information is invaluable. My PCP said he doesn't want me to do keto because I could go into ketoacidosis and die. I also am on CGM and do blood ketones. He said my high BS is my body producing the glucose from fat. What to DO?

[@martinklawinski2933]

You need top get your BS down top healthy levels. I doubt you have diabetes type 2 if you are reaching BS of 300 while fasting. That sounds like a body that has no Insulin at all and if it's the case, you are at very high risk of ketoacidosis, your Dr ist right. Don't play with your health, work with your Dr. If you don' t like the way he treats you, search another one, nur what you are doing now is suicide.

[@slay2525]

Search for a doctor that will work with you and monitor you implementing a ketogenic diet with electrolyte water and fasting

[@Thundercloud1969]

Dear Dr.Bikman, I follow your amazing work for a while now. I’m a health specialist from the Netherlands and I’m 54 years young. I’m very fit and lean and I eat a carnivore diet. Today I still have a small “worry” about my own blood glucose. I just wanted to check if my thinking is correct. When I was on keto my (European measurement) my glucose in the morning, fasted, was around 3.8. Since I’m carnivore I’m almost every day steady on 5.3 to 5.5 My question is, could this be because of gluconeogenesis? I know a thing or two about the processes in our body and I consider my self healthy but the question above is for me a bit like that itch you can’t get rid off, it’s on my mind for a while. Thank you for all the info you provide!!

[@TheStudentOfLife808]

This is a great push to focus on insulin rather than glucose ✊🏽 When is the best time for a type 1 Diabetic to have lowest insulin in their system for optimal health? Also, how do you decrease insulin usage as a T1D? Thanks

[@zoedraganuta8896]

Mulțumim!

[@insuliniq]

Wow. Thank you. Not at all expected, but certainly appreciated. You’re kind. Please let me know (and/or my team know) if there is ever anything we can do to help you. Thanks again. www.insuliniq.com

[@joecaz]

12:51 Hyperinsulinemia part is relevant because remember there are SOME CELLS that still respond to insulin as well as well as they used to as well as they ever did; they're STILL INSULIN SENSITIVE. So you have a handful of cells that are INSULIN RESISTANT, so even though insulin levels are elevated, they're NOT RESPONDING that well to it. And so, it generally is just a muted response anyway. However, the cells that are as insulin sensitive as ever are NOW OVERSTIMULATED; there's too much response to the insulin because there's too much insulin relative to normal healthy insulin sensitive levels.

[@tusker4954]

Could you discuss The Randle Cycle in this context. 🙏

[@Cya-bebetter]

Sleep. I’ve eaten keto (20g carb, moderate protein, high fat) for 6 months, have always woke several times during the night but now I can’t fall asleep! I have lost 56 lbs, feel great but am so concerned about the sleep issue. Is it the low carbs, no tryptophan and melatonin?? I hope you will address this in your next class. Thank you!

[@yoso585]

Could be all that crash in body weight. Body might be wanting to get up and make a kill

[@ActivateMission2ThisTimeline]

3 or 4 am wakeup, great question!!!!

[@47retta]

Since berberine lowers blood glucose, does it do so by means of increasing insulin?

[@bennieweber]

Thanks!

[@insuliniq]

This is too kind of you. Thank you. I appreciate it. Please let me know if there is anything we (my team and I) can do for you. You can always contact us on my website: www.insuliniq.com

[@sun-taekkwon1773]

책의 내용이군요 당뇨진단 20년전부터 인슐린수치로 알수 있었다니 대단한 사실을 알게되서 놀라웠읍니다. 무척 궁금한것은 인슐린저항성이 어떠케 고착되었는가 하는것입니다. 어디선가 그 원인을,극저염상태가,즉 인체의 소금농도 0.9퍼센트에 훨씬 못미칠때,세포내부 기아상태를 초래한다고 하는것을 봤읍니다. 그로인해 세포벽이 두꺼워지고,더이상 인슐린이 작용을 못한다는 기전을 설명하더군요. 인체의 체액의 소금농도가 터무니 없이 부족할때,그때부터 인슐린 저항성이 이뤄지는것이 설득력 있다고 생각됩니다. 소금의 필요성을 너무도 간과하고 있는것같아,참으로 안타깝습니다. 저염식이를 왜들 그리 목숨걸고 주장들하는지,도무지 알수가 없읍니다. 고혈압도 소금과의 연관성을 부정하는 정직한 실험결과가있고,오히려 과당이 혈압과의 연관성을 밝혀냈지 않습니까. 우리몸은 극저염상태로 부터 질병이 시작 되는것이라고,저는 강력히 말씀드리고 싶습니다. 세포대사의 기본인 세포벽에서의 인슐린신호의 둔화가 혈당수치를 끌어올리고,그에 대응한 인슐린증가가 따라오고 혈중인슐린수치를 높였다고 봅니다. 세포벽의 생리작용이 더욱 깊이 연구된다면 확실해지지 않을까 생각됩니다. 혈당수치보다 혈중 인슐린수치에 무계를 두신점,매우 인상적이었읍니다. 제결론은 인슐린저항성을 극복하고 당뇨약이나 혈압약을 안먹어도 충분히 우리 인체는 항상성을 되찾을수 있다고 확신합니다. 작금의 의료수준들이 심히 걱정스럽습니다. 당뇨약 먹다가 만성신부전으로 되어 혈액투석까지 이르는 수순을 뻔히알고,당뇨약을 끊을수 있다는 결과물들이 산더미처럼 증명하고 있는데,병원의 의사들은 왜 환자들에게 아무런 말도 없이 계속 약을 처방하죠? 일반 사람들은 의학지식이 없어 의사에 완전히 목숨을 구걸하는데,의사들은 그 신뢰를 묵살해버리고 있읍니다. 불쌍한 의료지식에 무지한 일반인들에게 너무도 고마운 정보를 주시니,깊은감사를 드립니다. 인슐린저항성을 극복하는 방법이 하루라도빨리 증명되고 대중들에게 전파되었으면 좋겠읍니다. 물론 저도 나름 근접한 해결책을 가지고는 있으나,보다확실한 앞서가는 분들의 처방이 공개되어 ,많은사람들을 살릴수있기를 기대하고 있읍니다. 의사를 신뢰하고 목숨을 맞긴 사람들에게,빨대꽂아 인생갉아먹는 의사의모습들 추잡하기 그지없읍니다. 의사로서 양심을 되찾기 바라겠읍니다. 당뇨약,혈압약 먹으면서 일반인들 삶이 얼마나 걸래가 되는지,누구보다 잘 알면서 왜 약을 평생먹으며 연명하라고 선심쓰는척 하는겁니까. 가증스럽기까지 합니다. 의사로써 챙피함을 알고 바로잡길 바랍니다. 밴저민빅먼박사님 감사합니다. 좋은책 감명깊게 공부하고 있읍니다.

[@adorableadornments1101]

So is high insulin the culprit with the dawn phenomenon. So if I fast after my dinner meal from 6:30 p.m. to my next thing I put in my mouth at 9:30 a.m. which is 15 hours and wake up and take my blood sugar and it is 170 even though I am eating a keto diet and I am type 2 diabetic, does that mean after that many hours the insulin I have has not cleared my sugar in my body? I do not take any meds for my blood sugar due to side effects. I appreciated your explanation of insulin resistance.

[@marypohja2812]

Excellent. Thank you as always. ❤is a decrease of fasting insulin from 10. -4.5 indicate resistance ?

[@insuliniq]

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@markleblanc451]

A great book (Why We Get Sick). Every metabolic problem revolves around insulin. The book ties it all together with a pretty bow. A must read for all low carb/keto/carnivore/Ketovore enthusiasts…….and everyone else!

[@yvonnekiwior9633]

❤🎉I am so so happy and excited to have this opportunity to learn about Metabolic Syndrome AND to have a professor🎉❤ My question is really a statement: I truly appreciate YOU and all your BRILLIANCE that you share and teach🎉❤

[@insuliniq]

thanks

[@ActivateMission2ThisTimeline]

​@@insuliniqHave you had any pushback or challenges broadcasting this insulin message out?

[@sanjaygandekar]

Hi doctor. Very nice video. I would like to know is there any connection between gut health and insulin resistance.

[@slay2525]

There is some connection in the leaky gut discussion, but not a lot of evidence.

[@krabbend8]

Thank you! how long would it take to reverse IR with an other lifestyle?

[@insuliniq]

Thanks for your question. You may want to go to out website and ask my team: www.insuliniq.com

[@alfredadrianjr.4702]

Doc...could epigenetic effects inherited from the mother's mitochondrial DNA have an influence on future generations? If so, how could this be tested? If not mito DNA then what nuclear genes are being modified if any?

[@rancayabyab6848]

What is the ideal body weight if we ideally want to metabolically healthy? Do we base that on BMI?

[@williammonahan8893]

DR Bikman...you stated that all cells do not become IR and some do with long term chronic hyperglycemia, are there cell types that are known to down regulate and those types that stay sensitive with IR ?

[@nowayout8773]

I wish everyone knew this or would try to learn about insulin resistance. The doctors seem to be leaving insulin testing off the chart and only testing glucose. There is too much evil in the medical world regarding metabolic syndrome. My 82 year mother in law blood tests omit Hba1c ( insulin levels) I am not against life saving medical procedures but the LDL , blood pressure medication, statins, insulin supplements are only making pharmaceutical companies richer. I am weary to get my blood tested. My LDL always freaks out the doctor till I tell them my side of high HDL and low triglycerides 60:79 I am lean, and have normal BP. By the way, the dentist is going to lose money because insulin resistance also drives up inflammation and rots the roots and gums. Seriously, every cell is affected. I was wrong about the Hba1c testing insulin. The nice person commented on my comment and now I know.

[@daniellem1838]

Hba1c measures your average blood sugar levels over the past 3 months not insulin levels.

[@nowayout8773]

@daniellem1838 I made a mistake. Thanks for the correction.

[@yoso585]

It’s what insurance will pay for that most docs test with. And they are only looking five years out. That’s the life of the average policy. Insurance companies count their beans well. Doc are hardly ever paid out of pocket. That’s just the way it is.

[@bryanj.mcentire3561]

Hi Dr. Bickman - Will you delve into the molecular mechanisms behind insulin resistance? What is the biochemistry at the cellular level that causes insulin resistance?

[@insuliniq]

Hi Bryan. Thank you for your comment. About a week ago, I did a lecture on this topic for the Cardiometabolic Health Congress that may help. Please let me know if you have more questions: www.insuliniq.com/dr-bikman-cardiometabolic-health-congress-presentation

[@williammonahan8893]

DR Bikman....Could you speak to a point l found extremely interesting....that being some references related to the 20 year time period for an individual to progressively move from IR to a full blown type 2 diabetic?

[@Eliese.]

Liking these classrooms! Is there any way the episodes can be numbered to help identify order?

[@insuliniq]

Great suggestion. Thanks.

[@jacquelinesmit876]

Thanx for the great info. I have some questions: do you test your insulin resistance with an FPG test? Also what should the range of the fasted ketones be? When you are on a carnivore diet (and sleep well) how long on average will you reverse your IR at the age of 60 yo female?

[@insuliniq]

You may want to go to my website and ask our team, using the contact form or chat bubble: www.insuliniq.com

[@doddsalfa]

Debunked often but still relevant

[@carol-annes5492]

Question: (1) Can metabolic inflexibility be reversed? (2) Why does the insulin stay high? Is it because the door doesn't open and it isn't used up? (3) If not all cells are insulin resistant why do the insulin recent cells drive the insulin levels? Is it because systemically they out number or may out perform the healthy cells? (4) If we increase our muscle % will that tip the scales and bring down the insulin levels?? Kevin

[@leeannruth1587]

Perhaps you could touch on glucose testing response that was within parameters at the clinic but after leaving produced an extreme hypoglycemic reaction. Frightening to the point of fearing losing consciousness.

[@esmewetterwachs7462]

Dear Mr Bikmann, I am confused. My A1C is 4.9-5.0, but: I have skintags (neck and armpits). I eat low carb for years now, 150 lbs at 5'9" and 15K steps per day. What should I look for because of the skintags? Thank you!

[@GoneCarnivore]

Is it keto or carnivore that i would have the lowest insulin level with. Which will i be in the deeper ketosis?

[@RobinLaMali]

I was born with skin tags all over my body - nearly 100 up and down both arms, under my armpits, and on the back of my neck. And I have struggled with my weight, pretty severe hypoglycemia, and a series of random health issues that doctors can't seem to figure out the cause of. With this in mind, can babies be born with insulin resistance? And can reactive hypoglycemia be caused by insulin resistance?

[@danielbraud6908]

I am on the carnivore diet( 5 weeks in). I'm wondering why my blood glucose levels remain 100 to 120 mg/DL? I do fast between meals 18 to 22 hours and my lowest BS reading has been 97. I do use ketone urine test strips and they indicate I'm in ketosis at 40 mg/dl. So I'm not metabolically inflexible. My assumption is I've been insulin resistant for so long that it will take awhile for my BS readings to lower. I've been diagnosed as type 2 diabetic, high cholesterol, high blood pressure & Erectile dysfunction. I'm 58 years old. Dr Ben what are your thoughts?

[@marciagarcia1332]

Would I ask my PCP to measure my insulin levels or could I do this at home?

[@joharris501]

Brilliant as always Ben! Wish the NHS here in England would address these issues, oh forgot, Big Pharma and Supermarkets would loose money! THAT'S THAT'S ITS ABOUT 😢 Some so called foods should be banned. Education in schools and most importantly our GP's educated. People have to learn this knowledge them selves in order to save their quality of life.

[@user-vg5df1tq5p]

Low insulin leads to fat burning, and elevated insulin leads to converting excess glucose to fat you stated: elevated insulin leads to sugar burning !!! For your clarification, thanks

[@Kyrani99]

Couldn't high glucose be due to a stress response that maybe is not ongoing but episodic? However the person is not engaging in any fighting or fleeing. So the insulin resistance happens because cells want to continue to uptake the normal amount of glucose amid a surplus of glucose.

[@stellat2405]

what is the ideal insulin serum count?

[@lumay333]

Are there any advances in treating Dtype 1 with diet? Why is it on the rise and why is uncurable?

[@ellemelbaus1129]

Have you read Dr Richard K Bernstein’s “Diabetes Solution”? Dr Bernstein has Type One diabetes and manages it with low carbohydrate foods. He is 89 years of age and still working!

[@kyrameekins]

Dr. Beckman, Is 10 ulU/ml ok? Albumin 4.4 Doing Keto lifestyle.

[@kyrameekins]

I should have added fasting insulin-10

[@Primetime_dads]

What about if your fasting glucose has been 115 for years but fasting insulin has been 3.6 Since this is not the insulin that’s up but the fasting glucose, what would we say then. A1c is 5.5-5.6

[@BethMannPresents]

I wish y'all would understand: many of us are doing everything we can to get good sleep. We're not all glued to our phone, drinking Diet Cokes pre-bed. Hormone levels change, these blood sugar disruptions affect sleep. I go to sleep at 9 pm every night, dark room, devices off, etc...and I awake at 3 am unable to get back to sleep. I'm chronically underslept. Its not about worry or excessive thoughts. Its not sleep hygiene. Its physiological.

[@philipmarx1819]

Have you tried a magnesium supplement like magnesium L-threonate? CBD oil? Listening to a sleep story to get back to sleep? All have helped me.

[@BethMannPresents]

@@philipmarx1819 As someone with years with of insomnia, there isn't any suggestions I haven't tried. Its a physiological issue, likely hormonal; its not about a racing mind or a need to relax more. Though cannabis oil does help (not CBD oil which I think is snake oil) but actual cannabis oil has helped; its just not tenable to take every night for a number of reasons. Thanks for your suggestions nonetheless.

[@philipmarx1819]

Exercise/being physically active can negate the deleterious effects of poor sleep. kzbin.info18pWUX5_ZMo?si=rYQXgQkdh9MBQsyh

[@cindy4678]

so if I have a glucose level going up (zero carb no less) 110 - 135 whenever I take it in the day, HDL in the 90's, Trigs in the 50's, LDL is abt 170. I really need my Dr. to check fasting insulin to figure out whats up. It used to be 80 to 110. Low thyroid symptoms that I can see but levels are within "normal" ranges. Dont know what to do. I listen to all you experts about all these things but I am not finding answers. I would be really surprised if I had high insulin.

[@yoso585]

As with me, I’d bet it is the liver. Just loves making glucose but doesn’t seem that there’s plenty out there. The signaling can be very complex.

[@julieponce3345]

I’d like Dr. Bikman to address Drs. Richard Johnson and Perlmuter’s view on uric acid and fructose , but in both their books they contradict themselves by suggesting people eat 3-4 fruits daily.

[@ActivateMission2ThisTimeline]

The fruit deal is weird. Fructose is like drinking alcohol they say but then some eat 200+ grams a day and say it's great for you?

[@graphicmaterial5947]

Some may say that insulin resistance on a cellular level is not actually a disorder, but more of a defense mechanism when the mitochondria have reached their maximum ability to create ATP and the cell needs to prevent damage to other organelles from glycation because too much free glucose in the cell is toxic. Is that interpretation wrong? Thoughts?

[@crescentconstruction4298]

I would say that's describing the same issue from a different perspective. The pathology is too much glucose, but glucose levels (in blood ) are kept in check by high levels of insulin, which jams it into the cell. Your glucose may be at 100 but it your fasting insulin is 15 - you likely have a problem because it's taking 5x the amount of insulin to maintain healthy glucose. The point being, monitoring insulin may indicate a metabolism issue 10 years sooner than monitoring glucose alone.

[@graphicmaterial5947]

So the underpinning cause is - as a certain youtuber have put it - that you're pouring carbohydrates down your stupid neck every day of your miserable life, huh? Got it!@@crescentconstruction4298

[@yoso585]

Think about the function of the liver and fat cells (unstuffed). If they resist, then there is insulin resistance. Sure, other cells can only take what they need, but it’s the job of the liver and fat cells to clean up.

[@graphicmaterial5947]

Hm. I've heard that glycation of the red blood cells and vascular endothelium are "sacrificial lambs" because they are quick to replace. So much to learn...@@yoso585

[@renus6015]

I have high ldl , statin is causing high liver enzymes....diet is not helping much....any solution?

[@insuliniq]

Many people benefit from becoming part of our Insulin IQ Community. Perhaps you would find value there, through group coaching and like-minded people working on their metabolic health: www.insuliniq.com/insulin-iq-community-membership-signup

[@richieheetebrij8189]

I think a person with Alcohol use disorder could have “metabolic syndrome” and not hit the criteria to be labeled insulin resistant. The alcohol use would mask the high glucose and high insulin at the time of testing but the person would still have a major fuel problem, as the fuel they are burning is acetate, and to some extent lactate, and when you run out you can’t burn fat because your fat cells are “ insulin resistant.” Perhaps there is such a thing as fat burning resistance? How else can you explain someone metabolically inflexible not being able to switch to fat burning mode when their insulin has dropped? Lipotoxicity? Perhaps “metabolic syndrome” is just as much a fat issue as a glucose issue?

[@karenmotlow3626]

so how does metformin work? its not a Sulfonylurea

[@mithidas4295]

When hyperinsulinemia in T2D fails to normalize glucose level how can Insulin injection do so and even can cause hypoglycemia?

[@insuliniq]

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@yoso585]

The injection is probably at a much higher amount.

[@stockinettestitch]

So…how do we remind our bodies how to burn fat? If I go really low carb, will I get unbearably exhausted? How long does that last?

[@insuliniq]

You may want to create a free Basic Membership on our website which gives you access to my introductory course, “Raising Your Insulin IQ for Improved Metabolic Health”. This may really help you with your questions: www.insuliniq.com

[@cherylpoulin9380]

Blood work shows my insulin is low and my blood glucose is low. Triglycerides are great, blood pressure excellent, and basically except for needing to lose weight, I'm a healthy 61 year old. I follow a low carb diet with intermittent fasting...why are by blood ketone levels never going above 0.3 at best? What does it mean?

[@insuliniq]

You can ask these kinds of question using the chat bubble on my website, if you’d like to: www.insuliniq.com

[@cherylpoulin9380]

@@insuliniq Thanks. I did. It was recommended I join the community.

[@yoso585]

Well, that’s just the status of the blood level. Does not measure production or usage. Some would say you are burning them right up!

[@insuliniq]

My team told me that you signed up for a free Basic Membership. Nice to have you with us. Stay in touch.

[@zachary813]

Morning glucose 107; ketones 1.4; BP 117/71. Carnivore a few years. Why is BG consistently over 100? Why doesn't my A1C come down?

[@thalesnemo2841]

Depends on time of day ! Mornings tend to high due to DAWN EFFECT !

[@engc4953]

Cortisol

[@zachary813]

@@thalesnemo2841 Yes, I take it in the morning. But I'm frustrated that I don't get the benefits that Ken Berry goes on about, like a low A1C.

[@zachary813]

@@engc4953 I have so much pressure and stress in my life now.

[@EthanE3]

Dawn effect. Check glucose at 2pm. Mine is 115 un the am and 80 at 2pm. All fasted and keto, sometimes carnivore. Its our bodies saying LETS GO! ITS MORNING!

[@thewrightoknow]

Please hold a classroom on how to overcome insulin resistance! I am doing 72 hour weekly fasts water only and eat only carnivore! Is what I am doing helpful to restore insulin sensitivity? How long does it take to restore insulin sensitivity?

[@erebus79]

Not sure you need to fast that hardcore but it will certainly help.

[@thewrightoknow]

@@erebus79 Any idea how long would I need to do this to cure or fix my insulin resistance. I am a type 2 diabetic and want to not have insulin resistance. Thanks for your comment.

[@LauraB.335]

It’s going to vary from person to person, depending upon how long they’ve been insulin resistant, etc. The only way to really know for sure is to consistently test your fasting insulin to see it go down. I know Megan Ramos from The Fasting Method used alternate day fasting for 6 months (she started out a little more slowly, but I don’t remember her exact schedule) to get rid of her pre-diabetes, fatty liver, and PCOS. She also, eventually, went to fasting M-W, then a 24-hour fast on Friday. She used the 3-day fasting to build muscle and reverse osteopenia. How long have you been doing it? Have you reversed your type 2 yet? If not, aim for that first, and it will certainly help with the insulin resistance. There are videos out there talking about this. Check out Dr. Sten Ekberg (he addresses this exact question). Also, check out Dr. Ken Berry.

[@thewrightoknow]

@@LauraB.335 Thank you, no I have not revered my type 2 diabetes! I have had diabetes for over 20 years.

[@LauraB.335]

@@thewrightoknow - just know you can reverse it. Megan Ramos gave an example of a woman who had type 2 for years and had been on meds for 30 years. She was able to reverse it in months with fasting and diet. The Fasting Method has a podcast and they’re on KZbin. It’s very inspirational to listen to them and know it’s possible to reverse all sorts of things. I wish you the best.

[@margaretmoffor3456]

What’s a good blood ketone level?

[@insuliniq]

Thanks for your question. You may want to go to our website and ask our team: www.insuliniq.com

[@idahobmihome]

The underlying driver of insulin resistance and type 2 diabetes. All other explanations for insulin resistance are downstream from this: kzbin.info/www/bejne/eKesfnavfbWjeqs

[@benoitconley1126]

Ben Bikman looks so much like Ed Harris

[@pehill1951]

Are there insulin reducing drugs?

[@monicali2608]

Spices can reduce insulin. But doing Keto is what to do in the first place. Solve the problem not suppression with wonder pills.

[@kiloboba]

Insulin is the big boss. Get your insulin in check and everything else follows!

[@sjoerdeggenkamp4004]

Why is insulin resistance correlated with belly fat or organ fat?

[@insuliniq]

You may want to create a free Basic Membership on our website which gives you access to Dr. Bikman’s introductory course, “Raising Your Insulin IQ for Improved Metabolic Health”. This will really help you understand the answer to your question: www.insuliniq.com

[@yoso585]

Fat cells full and nowhere for excess energy to go.

[@sjoerdeggenkamp4004]

@@yoso585 But why do the fat cells in the bell have no issue the get bigger?

[@lmyers9999]

Why can’t we develop an insulin meter??