16-Year-Old Vanishes After Going Out Partying: The Bizarre Disappearance of Karlie Gusé

Sixteen-year-old Karlie Gusé went out partying with her friends in 2018. When she arrived home, her parents noticed how disoriented she was due to drug use. Gusé admitted to her parents that she had been smoking and believed it was laced. When everyone went to bed that night, her family noticed she was missing from their Mono County home in the morning. Annie Elise 10 to Life breaks down the case of Karlie Gusé.
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[@LawAndCrime]

Subscribe to Annie Elise x 10 to LIFE: www.youtube.com/@annieelise/ Follow her on Instagram: instagram.com/_annieelise/

[@kristenmarielle3497]

No. What the heck you guys.. are you accepting money from her? This is ridiculous. At least show it in the thumbnail. You have lost my respect as a crime channel. You’re now posting videos from someone who has zero credibility and ZERO background in criminology. You have just degraded your channel and diluted it’s importance and credibility. There’s something sketchy and to be said about your account not posting her photo in the thumbnail or putting her name in the caption. It’s like a trap and I don’t understand why you need to make it that way. Just be HONEST

[@themomandthemaverick]

She's the best murder mystery vloger and podcast host!! Definitely should check out!!

[@unclefreddy2009]

What the heck is law and crime doing. Garbage

[@themomandthemaverick]

@@ultimatums1 that makes no sense. I do enjoy her content and also watch Law and Crime Network so them playing her video was solid since she doesn't talk to much BS and does a solid job of telling the background of the story.

[@VictoriaLynn59]

Thank you Annie ❤

[@corneliusdenise]

If your child comes home disoriented and thinks they were drugged, do not go to bed. Someone needs to stay up to make sure her symptoms don't worsen and she doesn't need medical attention. Hopefully they find her.

[@sarac1118]

Absolutely. It’s sad you even need to say that to people though.

[@corneliusdenise]

@@sarac1118 yes agreed

[@lottoo5693]

she cried for help and for her stepmom to call the cops

[@Kurzbraten]

This 'child' you are talking about was a 15 year old teenager! I find the stepmom was totally reasonable how she handled the situation - what exactly was on your mind the parents should have done with a teen, who got back high? Please do explain, I am so into your Ruby Franke take on this!

[@TheBakingSlave]

Ruby Franke take? Are you effing unhinged? A normal parent would take the child to the hospital. If they are freaking out and acting erratic and being a danger to themselves then you take them to the ER, clearly, since the girl is now gone and missing for years because she either freaked out and left or was killed by someone in that home....also, 15 isnt a child? Are you kidding me? The law disagrees with you, of course 15 is a child. Also, the OP didnt even say she was a child she said "when your child" Im an adult person, but im still my parents child. Its like you lack proper thinking skills. The girl is gone, more than likely dead.....thus why she and her story are on this channel, its not rocket science. I hope youre not a parent because your take on all this is terrifying and its people like you we end up seeing on these shows because they treat their children horribly.....@@Kurzbraten

[@TheLauren1113]

I don’t understand why they didn’t take her to the hospital if they thought she was drugged

[@اميرمادرا]

Yes your ritht here poor girl tho

[@VictoriaLynn59]

Excatly

[@Allynavarro2435]

Right? I understand the teens not taking her but her parents?

[@TheLauren1113]

@@Allynavarro2435 right. Something was not right in that home. You don’t video the kid and mock her. You get medical treatment when they are so disoriented.

[@TalLeGal]

It sounds like they may not be the kind of ppl who want to involve outsiders, esp govt agencies. Maybe why they didn’t take her to hospital? Didn’t want outsiders to know they were allowing her to get high?

[@millieharper51]

The parents should have immediately taken her to the ER

[@samanthacly6997]

Step Mom was too afraid to take her to the ER. She was to worried about getting a DUI and having CPS called on her other two children.

[@millieharper51]

Agree

[@VictoriaLynn59]

​@@samanthacly6997she could of called for paramedics but she didn't. She did nothing.

[@a.s.3676]

​@@samanthacly6997sometimes people see the half-sisters as a threat to the inheritance, they are simply jealous, or they have some other crazy motive to get rid of a stepchild. Of course it's just my suspicion that Melissa caused the girl's death or at least assisted in it.

[@marshapieroni6677]

Why. You would have, right? Why do you guys think you know all the story after watching a video?

[@CryptoChick57]

I’m a psych NP and her behavior is common with people who have smoked synthetic marijuana (e.g. K2 or Spice). Often times patients admitted to the psych unit for drug-induced psychosis thought they were smoking marijuana but when given a UDS, they had not.

[@SavingSoulsMinistries]

i would guess it was LSD or Shrooms. there was a kid in my town who took LSD with a group of 5 people and he started freaking out.. jumped off a second story fire escape with no shoes or shirt on, running down the street yelling and looking for his deceased mother. super scary stuff man. and that road was one of the busier roads in our small town. nobody saw him until a couple days later at school so i guess he ran over 3 miles home like that. its a wonder the cops werent called on him

[@sashasorensen5945]

I agree. I used to be addicted to k2, I saw many friends act just like this

[@austinrogie883]

Doesn’t last that long I would say lsd or mushrooms

[@maryd3403]

Marijuana doesn’t make you go crazy but, synthetic drugs do.

[@heatherstewart9300]

Spice was my first thoughts also.

[@catherinecroteau-pinney4085]

Melissa recording this poor girl instead of taking her to the hospital is so sus to me.

[@chameleonsoule314]

Super duper sus, her actual mama 1000% believes that the dad/stepmom had something to do with her disappearance

[@Kiq_Ash]

When i saw this on Annie’s channel i felt the step mom was strung out and for sure the step moms behaviour is extremely abnormal

[@Evelynlouise089]

It gives more ‘look at what I have to put up with’ and not ‘look at what you were like’.

[@3yearsago287]

At this day and age, ill just stop going out. That party life is dangerous.

[@cats.addict6457]

that's very true

[@Anna-xx1lv]

The types of drugs that are available now compared to the 70’s. How easily accessible drugs are now to teenagers. Drugs are not “clean” now like they were in the 70’s. Just my opinion.

[@elenabuiles1370]

​@Anna-xx1lv Absolutely, I completely agree with you..

[@VictoriaLynn59]

​@@The_Lost_Onea huge difference from now and the 70s

[@sashasorensen5945]

Everything is placed with fent now ​@@The_Lost_One

[@denise8791]

Yes! Bring attention back to this case! She was never found. I cant imagine the torture her family still experiences. 💔

[@graftme3168]

She was seen in the desert four/five years after she went missing.

[@kullulillu]

@@graftme3168 no! You are wrong!

[@graftme3168]

@@kullulillu Maybe so. But, how do you know?

[@mangographics225]

Why would they not recognise their daughter needed Medical care???!!

[@kayvee9094]

"Honey you think you were drugged at the party" okay we'll talk in the morning. WTF is up with these parents?

[@Legendary_loo]

Bro the girl had SMOKED before but they thought this was just a reaction from her… I mean I agree with these parents reaction to this is pretty questionable. Hope you come back home karlie

[@qthomas9166]

Your child is in need of medical attention and instead of taking her to the hospital, you just go straight to bed?! Parents these days bruh.

[@carlaredman2693]

Agreed 💯

[@ashleyhall8599]

Marijuana induced psychosis is REAL and very very dangerous. I do believe that’s what was happening to her and it’s so sad her family did not take her to the hospital. Very sad.

[@YTnotes]

I agree. Marijuana is VERY dangerous for women. Should be illegal for them to take, as they can't handle it. Remember the girl who stabbed her date?

[@renee1961]

It sounds as if Karlie was Absolutely Terrified! She didn't understand what was happening! A Psychotic Break is Very Scary for the person suffering it.

[@kellijanssen1171]

That child needed to be taken to the hospital immediately. Poor parenting.

[@VictoriaLynn59]

Absolutely 💯

[@a.s.3676]

Stepmother seemed to be more interested about getting proof for something (the recording of the child's interrogation/interview she made was disqusting).

[@Liverbird1984]

​@@a.s.3676 reminds me a little of that video Leticia Staunch took of Gannon (after he suppsedly burned the carpet)

[@NikNik-pp4tk]

Agreed 💯

[@antiafrosvengalis]

Irresponsible not calling 911 right when she showed those symptoms.

[@ingloriousbetch4302]

If it was shrooms or LSD, someone else would've reached as well, and/or her friends would've seen her taking them since they were never out of each other's sight at that time.

[@tiakriab600]

I've been following this story since Karlie went missing. Theres way too many inconsistencies from the get-go from her stepmom and her dad!

[@teresaslo]

SUS I agree

[@shanneni1007]

I check on this case every few years hopeing something will turn up! They let karlie down bad!

[@tiakriab600]

@@shanneni1007 So do I, she really touched many hearts!

[@chameleonsoule314]

Agreed 😢

[@amya6902]

She went missing the morning my son was born, I've been following since the beginning. I've always suspected her stepmom gave her something hoping to calm her down/help like Xanax or something but instead it made her worse. I initially thought they covered up her accidental death & hid her body but now idk.. I just don't think that's what happened. I believe she did wonder off through the neighborhood & out to the highway like witnesses describe. I was thinking "how likely is it that a kidnapper would happen to be driving by at that moment 🤔 & THEN I thought well just me, in my life from the ages of 4-15 have "almost" got kidnapped 5 times (THAT I'M AWARE OF) It is NAUSEATING to think how many men must have these thoughts & are ready to take advantage as soon as they get the opportunity. She was paranoid & scared of her own stepmom so I don't see her getting in the car with a stranger willingly so there was likely a struggle if that happened. Idk how well the police did their job and looked for signs of that though.

[@kilo.hotel_141]

Why is no one talking about the human remains found in the desert ? I’m very curious in knowing who that would’ve been if it wasn’t Karlie…

[@billfisher4156]

Indeed and the tracking of blood they found. Was that tested for dna?

[@dananelson9427]

Yes!

[@Muirmaiden]

@@billfisher4156 No results have been released for a reason. Dogs cannot detect or track DNA and Arpad Vass's device is a scam. This "search" took place in November and December of 2018. It was orchestrated by Karlie's father to mislead the public into believing that she died in the desert. When the scam to issue a death certificate for Karlie didn't pan out, the whole thing was dropped. Now, Zac and Melissa Guse are pushing the abduction/trafficked theory. Anything to divert attention away from them.

[@Beckaboo3397]

I’m at 1:01:03 and the fact that they didn’t call an ambulance or take her to the hospital when she was acting like this! Is beyond me!! First thing I’d be thinking is she’s going through a possible OD or at the very least some VERY adverse and dangerous reactions to something. I’m thinking at this point she died in that house and they covered it up so they wouldn’t get in trouble.

[@robinparmer5571]

I completely agree.

[@boomstickcritique902]

Sad to say she's obviously passed away at this point. She either died in the house and they are trying to cover up there bad parenting. Or she honestly did walk away from the house while still being somewhat dazed and most likely died by accident out in the elements while in a daze. Sadly if she did go randomly wondering around while still in a slight daze the next morning she probably did sadly die by just random accident out in the elements and one day her remains will probally randomly turn up.

[@misspeachy5626]

It really struck me as odd when Melissa gave Karlie Guse an energy bar while she was already feeling paranoid. Energy bars are meant to wake you up and boost energy, the exact opposite of what you'd want for someone in that state. Also, Melissa's conflicting stories about where she slept that night just add to the strange dynamic of the whole situation.

[@bingsballyhoo711]

There are mine shafts all over out there. If she was feeling paranoid I can't see her getting into a car with a stranger. How we learn from this: the parents should have taken her to the ER

[@joanna6109]

Oh, she defiently would have. She was clearly having a psychosis, and would have gotten into a car with a stranger to get away from the nightmares she was in.

[@mistyvaughn6356]

She was at the age where schizophrenia starts setting in, but without being able to talk to her no one will ever know. 😢

[@angkeats7111]

The stepmother is VERY suspicious. Did the Dad actually see Karly behaving this way? The fact the Stepmother was vomiting is a red flag. And also stating she was abducted and won't be found in the desert...like why would you think that when they live in the middle of nowhere.

[@Moe1313-2]

The stepmom said she was fine and that’s why she didn’t take her to the Er, but if she was fine, why did the stepmom video tape her?

[@juliaweber212]

For proof that happened I would and I would've called 911

[@FrancisKinsleyJr]

So fishy not calling 911 or going to the hospital.

[@renee1961]

I don't understand why she wasn't taken to the E/R! It definitely sounds like a Psychotic Break, Sadly!!

[@juliebrownlie5330]

The more i hear these cases the less i have anything to do with people. Its hard to spot the crazies initially. Keep yourselves safe folks.

[@jackieserritella4885]

She had a psychotic episode. This happens with marijuana sometimes- especially in teenagers. This is an emergency and needs immediate medical attention ( at an emergency room)This is so tragic 😢

[@Allynavarro2435]

I know seems like a lot of people agree that she should’ve been taken to er….small town middle of nowhere she definitely should’ve been monitored

[@joanna6109]

She should have gotten directly to a psykiatric hospital where she couldn’t escape, and where she was safe with professionals and get the right medication.

[@IRgEEK]

Not with natural marijuana. Synthetic marijuana possibly, since it is all chemicals and not marijuana at all, but actual marijuana does not cause psychosis. Making bad eating choices and sleeping soundly maybe, but not psychotic episodes.

[@Elitemage]

Could be signs of bipolar as well.

[@girlontv]

@@IRgEEKactually there are many studies done on the link between psychosis & marijuana! The risk is higher for ppl who have a family history of mental illness. Marijuana is involved in approximately 50% of psychosis, schizophrenia & schizophreniform psychosis cases. Its very interesting to research, the effects are still not well understood. 😊

[@janice8514]

Wow. I grew up in the 80-90's, and I was not careful by any means. I got very lucky, that's for sure. The poor girl, and her family!😢

[@stevens69411]

Drug induced phycosis? Poor family

[@EmilyEverglot]

Ever since the first time I heard this story I figured Carly had a drug induced psychosis. My heart has always gone out to poor Carly. Psychosis is such a confusing state.

[@snoozeflu]

Please keep in mind law enforcement will say anything in order to get information out of you. "We are not interested if you did any drugs" is such bullcrap. They will say that now and then come after you later.

[@samanthacly6997]

And some of the law enforcement went to school with the family . Bishop is a very CORRUPTIVE town. Most all grew up together , they’ll have got each other’s backs. 💔 for Karlie

[@angeliquebelluomini7797]

The story of Karley is heartbreaking.

[@nataliapozzi9305]

Stepmother doing the video without Karlie's dad .... Seems off

[@taxlawandyou9777]

Kudos having Annie Elise 10 to Life breaking down this case of Karlie Gusé! Her professionalism is bar none to many.

[@gabrielakarl3859]

The morale of the story: dont do drugs

[@cloftin2010cl]

Loveee Annie, also Law & Crime! Glad to see this collab

[@mamapandas5740]

Yes, I just said that. She's done a couple on this channel now!

[@hmbogi]

I wonder if her parents did something to try to sober her up and she ended up dying by accident?

[@StoneCastleSystems]

Thank you for making this video. Hope this gets solved.

[@stinkinlinkN]

This is a case that is so bizarre . It’s one of those cases that will get solved 20 yrs from now

[@leegalen8383]

All police departments should have drones for search efforts especially in the wild west.

[@sandibaker5298]

The scary thing is, authorities say that “there are dozens of serial killers in the US at any given time”.

[@alwaysdisputin9930]

& slavery still exists

[@kaylamarine]

Truly believe that Mellissa knows EXACTLY what happened to Karlee.

[@Deethehiddengem]

I don’t think Melissa did anything to her but it sure was negligent for the parents not to take her to the ER or call 911.

[@adamcoleman2896]

Did she take a polygraph.

[@Youallaresoslowgethelp]

@@adamcoleman2896those aren’t real , they don’t use them in court

[@marshapieroni6677]

Melissa did sound weird

[@ANWFineArt]

I think the fact the dad checked in on her and her eyes were open and then Melissa said the same thing makes me believe she passed and they hid the body

[@brandy195]

Thats so heartbraking to hear her speak to adult she trusted for help and she was ignored.

[@emmasanders6226]

Psychosis full stop. Father and stepmother are only guilty of not getting her professional help when clearly she had lost the plot😢 Still a chance she's alive somewhere if the desert didn't swallow her up

[@juliaweber212]

I agree

[@dargful]

Sounds like a bad shroom experience.

[@outwardbound2241]

Why is no one talking about the neighbor who allegedly saw her while he was sitting in the hot tub at 6 in the morning. Could be a crime of opportunity.

[@Hadacattoo2]

But another neighbor in another area saw her 30 ish minutes later

[@crickettmoon7082]

@@Hadacattoo2Are the two people who “Saw” her connected in any way?!🤔

[@Camey71073]

They most certainly should've taken her to the hospital.

[@babyclown]

This case will never leave my mind!

[@edit_bee]

Yeah me too i came back to see if she was found

[@kar241]

i'm glad you're talking about her. i think of her every now and then. i have a feeling the dad and/or stepmom did something. she'll be missing for 6 years in october 😕

[@juliebrownlie5330]

Yeah. I think they are covering for Melissa. They KNOW what happened to her.

[@susanmilos6251]

@24:30 Melissa said that Karlie kept writing something on a piece of paper throughout the night.

[@clipsofmma]

The step mom is suspicious but that does not mean guilty It seems quite possible that 1) Karlie had a psychotic episode, went wandering around, and got picked up by some bad guy 2) she wandered into the desert and got lost and died 3) was killed by her step mom and/or dad and dumped somewhere in the desert

[@mcfrenchfry2196]

Annie Elise is awesome at true Crime! And yes The EXTRA long telephone cord Was Like “ whaaaaow “ 🤙

[@KDM209]

Even if the parents aren’t directly involved in what happened to her, they didn’t take the situation seriously and that is so tragic. I don’t like the ‘parent’s’ behavior at all.

[@Kelly_B6x3]

59:59 "she says youre gonna kill me", they should have looked into the parents wayyy more

[@renee1961]

Prayers for her Safe Return, and Answers.💔💔💔💔🙏🙏🙏🙏

[@AmyAndThePup]

Love Annie! Always so thorough. It's like sitting with someone on a couch while they go over the entire case in all its detail and different perspectives of people around the world. I sincerely hope Karlie is alive somewhere. But there are so many unknowns here... I don't know what could have happened, though the DNA from bone fragments thing sparked my curiosity.

[@a.s.3676]

Oh, this was the case were step mother seemed to be pushing her to death... (her sadistic way of speaking while recording her etc.) It made me suspect step mother killed her.

[@tarasherman2714]

I love 10 to life! Thanks for giving her credit for the video!

[@Crimeandpunishment65]

Why is the world Didn’t the family call 911. I would have. I am not blaming them but man. Heart breaking.

[@Mashenka6564]

What is Dr. Phil a “professional” of exactly? He’s not even an actual doctor… professional TV show host?

[@wendywonnell9020]

He's a complete charlitan. Can't stand him.

[@1stdegreetea494]

Oh that's easy... He's a professional exploiter.

[@Knuggy_54]

Yea I've seen alot about this case over time. I think this is 1 that definitely needs answers. Everything about it just seems off. Idk it feels like secrets are being held in a big circle and don't want it to get out.. If she is alive or passed idk but as a random person that cares answers are absolutely a must. Sad really the whole situation horrible

[@samanthacly6997]

Let’s just hope when Karlie’s two younger brothers are of age HOPEFULLY they’ll speak up. That’ll be Karlie’s ONLY chance. Her x BF is too much of a wussy to speak up of what happened that night.

[@mangographics225]

Great recap of this case! Thanks!

[@katmack4215]

I've always thought that Karlie walked out to the road,and ran into some that meant her harm..😕 My first inclination was that she walked off and got lost in the Mountains,but I think they would have found her,if that was the case.

[@SheLoves2Learn111]

Lol, me too, I don’t smoke because it makes me too paranoid so I can’t help you out with the diff strands. 😜

[@TrinaRobbinsCunningham]

This poor young girl, I'm deeply disturbed and uneasy about this whole situation rn.

[@NurseJhonna]

Yay thank you for doing this I’ve been asking forever ❤🎉

[@jtd1349]

Girl you said kickback and I had a trauma response 😂😂😂😂

[@moirad3895]

Why didn’t they take her to the hospital?!?!?!

[@renee1961]

If Melissa didn't see her leave, how would she know what Karlie was wearing?? And how would she know Karlie was carrying a piece of paper??

[@fiverrtopranktips]

That part

[@leegalen8383]

It was the neighbor who described that to Melissa

[@carolfiggins9122]

Never called 911 in freezing cold??

[@msdhinMT]

@Annie - so surprised and happy to hear your voice on this Law and Crime video!

[@outwardbound2241]

She has done several videos for them. Nothing new....

[@latenight6750]

Yes this my first time seeing her here wow 🤩

[@ashleelalasmith2792]

I still think the step mom had something to do with it

[@mamapandas5740]

Love seeing you on this channel, Annie Elise! Now, im snuggling in to watch this episode tonight ♡

[@renee1961]

Thank You, Law and Crime for sharing this video!

[@tanasue77]

Wow! Those parents sound pretty stoned or something themselves! Get em Nancy! Thanks Annie. To many kids going missing these last 4 years!

[@lathamroman4599]

That was really great job I never heard anything about that story

[@Evelynlouise089]

My stepdad went missing once. He left the house in his car and my mum got messages from him saying he wanted to end his life. We phoned the police. The first thing they did when they came to the house was check EVERYWHERE even though we told them he had gone out in his car. He was okay in the end.

[@renee1961]

I don't think it's wise to assume what a Missing Person is wearing.

[@CarisstaRashele]

This case will always bother me

[@-thegrid]

Crazy story. Annie you are stunning! Thanks for sharing

[@Augfordpdoggie]

why is a 16 yr old out partying?

[@eileenperez4887]

It definitely just sounds like she's not missing, she never left her house. She's there somewhere

[@glenniskoay]

Why would parents let their children use drugs? If a person is acting erratic, shouldn't they be worried? Or did this happened before so they scoff it off as something normal?

[@Jaim-]

Sister is sus AF. How is she going to one minute say Oh it's just marijuana and then the second oh maybe you'll learn your lesson now. Recording her , saying she's sick of her at this point etc.... Then the family not taking her to the hospital. The symptoms almost sound like "crack" side effects , extreme paranoia.

[@KevlarSammy]

Did they stop searching the desert for her? That is a lot of area to search.

[@mizzyride]

Pretty easy. The blood that was found 3 miles away by the quantum oscillator. Was it her DNA or not?

[@kevinkershaw1209]

Great report on this case! It’s been on the tip of my tongue this week (forgot the name) and, boom, here it is! Your definitely getting a new follower 😎

[@michellehinson-x1u]

THIS CASE IS CONFUSING.

[@Camey71073]

Love seeing my true crime bestie on law& crime!

[@CarisstaRashele]

Look at all that land they had to hide her in 💔

[@fabiolanevarez2665]

The dad sounds drunk during the interview 😮

[@antiafrosvengalis]

They got rid of her, bottom line. They thought she was a nuisance. Why we going through all this? It's very clear what happened.

[@anneadams6105]

He's either drunk or high. I love Nancy she's not afraid to ask the tuff questions.

[@booxluvx3]

Is this a reupload? I feel like I have already heard this story from Annie.

[@dannisunshine7228]

I wouldn’t be surprised if she’s living her life in a homeless camp somewhere. Seems like a psychotic break. You’d be surprised how many homeless people are “missing”. They’re hiding in plain sight, but off grid.

[@valleygirl2530]

And you know this How & Why?

[@esthersiersema]

I would have called an ambulance 🤷🏼‍♀️

[@Knuggy_54]

Even though I really do hope everything turns out well. The obvious by not even being heard or seen from again is brain racking

[@sydnigrauberger5984]

Well described and analyzed. Thank you.

[@oyolaviviana]

We need update on this case please and thank you

[@xxlongino]

This is a very tragic story. I was hoping that at the end there would be some CLOSURE. 😢