Limb development in vertebrates

[@hardcorefishsticks]

my left ear enjoyed your video

[@keshavkoshish6467]

Lol

[@Smallbutmightywords]

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[@Somini5933]

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[@noumansaeed7853]

Same 😄left ear enjoy fully

[@ambeeshrolta8000]

Your comment helped me to know that my earphones are working well. Thanks 😂

[@Chemistry_4All]

Limb formation results from series of epithelial-mesenchymal inductions between the mesenchymal cells of the lateral plate mesoderm and the overlying ectodermal cells. Cells from the lateral plate mesoderm and the myotome migrate to the limb field and proliferate to create the limb bud. The lateral plate cells produce the cartilaginous and skeletal portions of the limb while the myotome cells produce the muscle components. The lateral plate mesodermal cells secrete fibroblast growth factors (FGF7 and FGF10) to induce the overlying ectoderm to form AER.[3] The AER reciprocatively secretes FGF8 and FGF4 which maintains the FGF10 signal and induces proliferation in the mesoderm.[citation needed] The position of FGF10 expression is regulated by Wnt8c in the hindlimb and Wnt2b in the forelimb. The forelimb and the hindlimb are specified by their position along the anterior/posterior axis and possibly by two T-box containing transcription factors: Tbx5 and Tbx4, respectively.[4][5]

[@reettata]

My lecturer gave such poor lectures on this subject - you've saved me thank you

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@taniaancyjohn6457]

Thnk u so much Sir..I am an AMRITA student and i m having developemental biology exam tomorrow..i only listened to ur lectures..itz crystal clear ..thnk u so much sir..god bless u

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@abdulsalmansalmankhan601]

Sir u made it simple and easy Thank you

[@shomusbiologyofficial]

You're welcome

[@MissWatermelonify]

Dude, I don't understand anything at all about this stuff, I'm just an illustrator lol. Last time I studied biology was in high school, but a random teacher hired me to do a motion graphics video to help his alumni understand his course, and I just had to look up stuff to be able to know what to draw. I was feeling completely lost until I found this very well-explained video. Thank you so so so so much.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@kalyaniabburu4873]

Explained very well sir.Full information regarding limb formation.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@aesharao4311]

Sir can you please make a video on morphogens and morphogenesis ?

[@bengipolat3791]

great video! you always help me a lot!! thanks

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@sbbiswas4]

Thank you sir for such an informative video

[@manasp5201]

thanks bro for ur video ,that helped me in my exam very much .

[@shomusbiologyofficial]

+Manas Ranjan Panda glad it helped

[@lakshmitilakkarri4706]

Sir Limb is formed from lateral mesoderm??

[@axt202]

sir i have a doubt is that limb bud is actually formed from ectoderm?? i studied that it is from mesoderm and the lateral mesoderm and somites move to a region below the ectoderm and proliferate. Thereby a bulge is formed, that pull the ectoderm outward and it is not an outgrowth of ectoderm. Is that correct???

[@emaalbrechtova5718]

Annie Xavier yes, it is.

[@Chemistry_4All]

Limb develops from Lateral Plate Mesoderm. Bro you just need to edit the lecture plz. Thanks a ton.

[@souvikdas1960]

LPM INDUCES ECTODERM TO FORM LIMB BUD...CHECK WIKI

[@AdityaRaj-zk9eh]

thanks

[@shomusbiologyofficial]

You're welcome

[@bijetaroynath8651]

very helpful sir..thank u

[@witty_me]

Tysm

[@shomusbiologyofficial]

You're welcome

[@enassamir3274]

Please explain relations to hoxa genes

[@imtiazahmad5631]

helpful video. plz do upload videos on muscle, heart and kidney development .

[@cinextravel]

Did u make the Suggestion /Hit map video. I'm unable to find 😣

[@saritasharma8470]

Sir there's no sound in this video !!!

[@shomusbiologyofficial]

Use both earphones

[@kareenaafzal5804]

thanku soo much sir...

[@shomusbiologyofficial]

+kareena afzal you're welcome

[@kiransharma11111]

Iska pdf mil skta h?? Apka koi telegran h

[@fahimalamnobel4789]

sir do u have anylecture on MALT

[@pragyaagrawal5663]

Why is the video not audible? Please take care of the audio thing in the upcoming videos.

[@shomusbiologyofficial]

It's audible. Use both headphones

[@kalyanidhruw1706]

helpfull .... thanks

[@shomusbiologyofficial]

+kalyani dhruw you're welcome

[@rifanbudi34]

Human creation in Quran وَلَقَدۡ خَلَقۡنَا ٱلۡإِنسَٰنَ مِن سُلَٰلَةٖ مِّن طِينٖ We have created man from an extract of clay. (Surah Al-Mu'minun, verse 12) ثُمَّ جَعَلۡنَٰهُ نُطۡفَةٗ فِي قَرَارٖ مَّكِينٖ Then We made him a sperm-drop in a firm resting place. (Surah Al-Mu'minun, verse 13) ثُمَّ خَلَقۡنَا ٱلنُّطۡفَةَ عَلَقَةٗ فَخَلَقۡنَا ٱلۡعَلَقَةَ مُضۡغَةٗ فَخَلَقۡنَا ٱلۡمُضۡغَةَ عِظَٰمٗا فَكَسَوۡنَا ٱلۡعِظَٰمَ لَحۡمٗا ثُمَّ أَنشَأۡنَٰهُ خَلۡقًا ءَاخَرَۚ فَتَبَارَكَ ٱللَّهُ أَحۡسَنُ ٱلۡخَٰلِقِينَ Then We turned the sperm-drop into a clot, then We turned the clot into a fetus-lump, then We turned the fetus-lump into bones and We clothed the bones with flesh; thereafter We developed it into another creature. So glorious is Allah, the Best of the creators. (Surah Al-Mu'minun, verse 14) Those are many other version of translation. But understanding arabic langguage is the best way to get the true meaning of the verses. Thanks

[@uncleStalin]

Can you take your bull shit out of here ?

[@akhilaks7597]

Limb is developed from mesoderm, not ectoderm

[@adityapareek5122]

sir I am prepare Csir net but not selected you give me advice

[@priyalsharma028]

Insufficient information. Did not explain the role of retinoic acid.

[@niazmughal3394]

thankuuu so much ....😍😍

[@Robuste_fille]

sound ?

[@shomusbiologyofficial]

It's there

[@Robuste_fille]

@@shomusbiologyofficial It's quite surprising. It's not audible in any earphone. I tried multiple functionally proper earphones.

[@dipanwitaghosh6988]

sir please give suggestions for csir net june 2017.plz

[@chandanverma5250]

Information was look like given to 10th std students

[@meenakshikumari7821]

I think u have no idea about syllabus of 10th standard . Plz check syllabus of 10th standard

[@pawanbakthiyal2759]

So much confusing

[@shomusbiologyofficial]

Watch it couple of times. The topic is complex

[@valentinalazarova4159]

[@shomusbiologyofficial]

Thank you

[@axt202]

sir i have a doubt is that limb bud is actually formed from ectoderm?? i studied that it is from mesoderm and the lateral mesoderm and somites move to a region below the ectoderm and proliferate. Thereby a bulge is formed, that pull the ectoderm outward and it is not an outgrowth of ectoderm. Is that correct???