Рет қаралды 159
Biomolecular Thermodynamics and Calorimetry
Speaker: Chris Johnson, MRC Laboratory of Molecular Biology, UK
2024 Introduction to Biophysical Techniques
The LMB Biophysics Facility houses a wide range of state-of-the-art and in-house built instruments that enable the molecular characterisation of macromolecular size, shape, mass, stability, binding affinity, dynamics and interaction kinetics.
The facility is primarily intended for hands-on research by students, postdocs, and group leaders, who prepare samples and make measurements. Biophysics supports users in advice on experimental techniques and results, training and in collaborative research.
In this video Chris explains the thermodynamics of biological equilibria including the relationship between binding constants, free energy, and entropy and enthalpy to enable users to understand how isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC) can be used to understand biological processes. The practicalities and applications of each technique are discussed and how data should be interpreted.
The Biophysics Facility is headed by Stephen McLaughlin, supported by Chris Johnson and Chris Batters.
Read more about the facility here: www2.mrc-lmb.c...
You can find more videos from the LMB 2024 Biophysics Techniques Lecture series here:
• Biophysical Techniques...
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