Making an old hypnotic sedative and preservative

[@MashaRistova]

When I was in rehab over ten years ago the doctor there prescribed Chloral Hydrate to everyone so they could sleep through their withdrawals, and that shit is STRONG. I actually loved it lol. Felt like Xanax times infinity. I went back to that rehab a year after the first time and the doctor said he can’t prescribe it anymore because it had since been completely taken off the market. I guess it was a pretty ancient drug, but it worked soooo well. Especially when you’re going through withdrawals and can’t sleep. (I’ve been clean for 2.5 years now if anyone cares about that part of the story)

[@samdessino8635]

Hey, I care :) that shit is one hell of a demon and I'm glad you were able to make it out on the brighter side. I'm proud of you and thank you for sharing your anecdote

[@That.Lady.withtheYarn]

I'm glad you're clean. Contrasts 💐💙

[@therealbuttsmcgee]

congratulations on getting clean! that's a hell of a thing to overcome

[@worshipwormking2327]

congrats on getting clean! shit ain't easy, and I'm proud of you

[@rowanandwillowsdad]

well done

[@HclPudding]

"Today, we're going to be extracting uranium-234 out of a cheesecake and refining it to weapons grade."

[@spvillano]

Go right ahead. U-234 is not fissile, so your device, should the somehow be rich with the stuff, wouldn't even fizzle.

[@dadillen5902]

I make a weapns grade Chocolate Cheesecake. It a weapon of mass induction. Even one slice will induce a substantial increase in mass.

[@originalketchup7498]

@@spvillano wut?

[@Thugstenium]

@@originalketchup7498 uranium 244 isn't all that radioactive, uranium 245 is the one used in nuclear reactors

[@spvillano]

@@Thugstenium no, U-238 is the main ingredient in natural and high enriched uranium, U-235 is fissile, the thermal neutrons then transmute the U-238 into fissile fuel. U-238 is fertile, but not fissile. There is no such thing as U-245. U-238 is the heaviest isotope of uranium, with plutonium starting at 239. Curium has an atomic mass of 248. Still, U-235 isn't exceptionally radioactive either, given its half-life of 7.04x10^8 years. The shorter the half-life, the more radioactive the element is.

[@ezg5221]

"We need to wait for it to cool to around 50-60°C. We don't need a thermometer or anything for this, we just need to wait until it stops hurting to touch it" Words of a true scientist

[@moralesriveraomar233]

That's how we did it in ny school

[@Patriotgal1]

Yes- but does it still taste like shit?

[@HelloWorld-lg1pz]

lmfao

[@gordongiobanni7543]

😃

[@saltybildo4415]

Lol

[@drizzt495]

If anyone is interested, the "black box" technique that Nile stumbled across to precipitate the crude after it initially oiled out is referred to as "trituration." The term is not really used in the chemical world outside of organic synthetic work; however, it is a common term in pharmacy, meaning "to create a fine powder" (e.g. crushing a hydrated solid with a mortar and pestle prior to compounding). For organic chemists, trituration is (much like recrystallization) a bit of a shot in the dark--polarity and weak/strong solvent interactions are not easily trended on linear axes, so finding the right addition solvent/temperature/conditions is often an exercise in trial and error.

[@HioshimaFried]

As a dude who failed chem/psysics/all that jazz in school as a kid I just wanna say that your passion and pure knowlegde of these subjects is a joy to behold.. I might not get all the techincal details or lingo and i might confused one name chlorobutanol with chloroethanol but I get the feeling that i understand more and more with each passing video.. So keep it up mate, you are doing good work and honestly better than many other teachers

[@ShamanZaZa]

Even literature!?

[@alexfitzgerald3919]

chloro=chlorine, -ol=alcohol, butane=4 carbon chain, ethane=2 carbon.

[@silasanderson6058]

I'm not good at chemistry myself, but i really do enjoy watching Nile's videos, they're really well made and he gives a really thorough explanation.

[@2davivadiva]

Will I hated chem and was bad at it in high school but jsut took it again and really like it. It seemed to click a lot easier maybe it just takes some time. Or keep staying engaged with it. Also videos like this that relate it to real life help connect those neurons!

[@offbrand_2863]

You don't even really need to be interested in chem to like them either they are just unique and he does things that most people wouldn't

[@rumeunner3245]

Me neither but they are relaxing to watch.

[@missbirb9692]

Yo Nile. You forgot to test the "hypnotic sedative" bit on camera 🙄

[@ללאכותרת-ט8ל]

He is not Cody to do so...

[@lithiumlight6128]

give it to Cody then...

[@Just_Sara]

Though he did test acids on his hand.

[@ללאכותרת-ט8ל]

Most acids are not so horrible as someone's thoughts.

[@deplorableamerican9451]

Wie Schade 😂

[@Satelitko]

Edible Chem - Chlorobutanol

[@yellowgoose5043]

Hahahaahhahahahaa

[@thomasgarbe8354]

come on. One-year-olds only put everything into their mouth.

[@pandemicgrower4212]

@@thomasgarbe8354 and? I make tch and cbd edibles all the time. It's the adults responsibility to be a grown up and put things away out of reach.

[@1987Videolover]

NaCl technically edible and a chem

[@gregmcb5305]

Any one else not understand this?

[@StarsForward]

"In today's video, I'll be demonstrating how to synthesize a felony charge." ~ NileRed.

[@seanp9157]

With items you may already have at home!

[@Sp00kq]

@@seanp9157 you'd be amazed at the amount of very illegal shit you could make with ingredients you probably have at home

[@scottpilgrim8164]

imo better than that anal lube cocaine cutter synthesis

[@LawTaranis]

@@Sp00kq DMT extraction is just a matter of isopropyl alcohol and patience.

[@BrianKeithPREPPER]

That's funny, coming from someone with a profile pic on google that looks like a "lineup" pic from the county lockup lol

[@vikramkrishnan6414]

"All I need is acetone, chloroform and sodium or potassium hydroxide", also known colloquially as a "Ted Bundy"

[@Phantom0fTheRouter]

But what if you used all your acetone to make the chloroform?

[@Sue_Me_Too]

@@Phantom0fTheRouter It's pretty cheap online

[@Phantom0fTheRouter]

​@@Sue_Me_Too - that whooshing noise was definitely a ghost Ray... not you being clueless.

[@fuzzybutkus3951]

@@Phantom0fTheRouter great reply man.

[@windhammer1237]

Too soon

[@Thyagohills]

I liked the Biology touch on this one.

[@NileRed]

Thanks!

[@thearctic7919]

its pretty epic

[@gogear131]

Nile you taught me what a year for chemistry couldn't do.i could never understand how it works but I have watched enough to see it work...thank you keep up the great content

[@NileRed]

:)

[@vittoriovizzini]

@@NileRedhow much NaOH do i have to use ?

[@b0ssvevo603]

For those saying it should be "1,1,1-trichloro-2-methylpropan-2-ol" this is chlorinated tert-butanol and it is shortened to chlorobutanol, no chemist uses the systematic names after high school. Imagine professionals performing time sensitive reactions asking across the lab, which is more practical? "hey can you weigh out 5 mmol of beta-carotene?" or "hey can you weigh of 5 mmol of 1,3,3-Trimethyl-2-[3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-1-ene?" hmm?

[@Lunnderbolt]

Ay Bo0o0o0oSs the second one is more practical dumb ASS

[@MisterDoctorBaconman]

I have a borderline-vexing amount of respect for this globally-available short-form statement which has been digitally uploaded in order to be available to the public audiences of the domain known as KZbin, run by Google. I like this comment.

[@thatplane3865]

Ay Bo0o0o0oSs what about isomers? Also i like the long names but I wouldn't point it out like that one stupid wise guy

[@debug9424]

For isomers, just specify the part that makes the difference

[@thatplane3865]

CodeBurger yeah, i knew that in the back of my head somewhere

[@tombeierle25]

I’m not surprised a mix of acetone chloroform and potash sterilizes things 😂

[@bluerie._.3021]

You know what? Nile is the only person I wouldn’t be suspicious of casually having chloroform laying around. And there’s not a lot of people that I would say that about.

[@akuiori]

i agree, i think he is somehow more trustworthy than those that watch his videos...including myself...lol

[@spvillano]

It's actually not all that uncommon of a lab reagent. Obviously, one uses it under a fume hood.

[@trueKENTUCKY]

did you even graduate kindergarten?

[@spvillano]

@@trueKENTUCKY did you get credit for skipping every day of kindergarten?

[@Mr371312]

Its a pretty common solvent, like ether. Media pushed it out of proportion.

[@VideoPerfection]

When you tested the anti microbial properties, my jaw dropped. One of the most interesting videos I've ever seen on KZbin!

[@raphigysin1699]

Hey Nile, Im a chemical lab technician in apprentice and your videos are literally perfect for my interests. But I would found it really interesting if you could do some kind of analysis, for example a tlc, it's very simple and fastly done to show the qualitive purity of your product. Keep it up!

[@dr.OgataSerizawa]

….or, if you have a mass spectrometer laying around you could use that.

[@spookywizard4980]

how the f**k do you keep finding interesting compounds to synthesize that are SO SIMPLE. Every single thing I look up requires some next level chemicals like some coked up enzyme that won a Nobel prize to synthesize 😤

[@AC0KG]

Spooky Wizard it helps to research inventions from the 1700s through early 1900s. Lots of intetesting tech from that time period is now achievable in the home lab.

[@spookywizard4980]

AC0KG Where to start?

[@AC0KG]

Spooky Wizard depends on what you are interested in. A good option is to just read about notable chemists from the 1800s. When you see something interesting, see if you can find Royal Society publications on the topic. When you find something that looks good, look it up on Wikipedia and published papers to see what the modern methods are. Also there several forums for amateur chemistry where you can read other people's ideas and get input from lots of very knowledgeable people.

[@spookywizard4980]

AC0KG thanks! that's a good idea. I've been looking at sciencemadness haha it is pretty useful

[@NileRed]

I just stumble on them. I keep reading about one thing and then it mentions something else.

[@JamesRyhl]

so when are we getting a video on making methamphetamine

[@bsadewitz]

That is one of those things where one probably shouldn't be doing it if you need an instructional video.

[@coreysayre1376]

@@bsadewitz Perhaps, but there's an argument to be made that if the crazy traphouse next door had access to educational how to videos the chance that I get blown up as collateral damage might decrease.

[@bsadewitz]

@@coreysayre1376 Oh, well, why didn't you say so? ;-)

[@bsadewitz]

@@coreysayre1376What I meant, though, is that anyone who knows enough chemistry to carry that out would know which reference materials to consult for anything they'd ever want to know, just as a chef would know how to find and prepare a recipe from a cookbook. Honestly, it might be a better use of your time to find information on proper lab technique and safety precautions.

[@coreysayre1376]

@@bsadewitz I get what your saying. More than anything my comment was meant as in half jest, half contempt for the failure that is prohibition in all it's forms. Ppl who wanna do drugs, will. The real collateral damage is that as a supposedly free American, I cant do the things I enjoy the most in life, as parts of them gradually are regulated out of reach. Sorry for the tangent--How humans have not figured out that prohibition invariably has the opposite of intended effect, especially when there is hard scientific showing this--This vexes me greatly.

[@JAzzWoods-ik4vv]

>complains that No one gives the proportions >proceeds to not give proportions of ethanol-water mixture

[@jewe37]

lol. youtube suggested the chlorform video to me earlier today. the alorithm really is improving.

[@theLuigiFan0007Productions]

Well, technically it's a self learning AI, so one it starts figuring things out it should improve faster and faster. Provided they don't make too many adjustments to the weighting in too little time and confuse it. Not even Google knows what the AI does inside, they just give it goals, most likely increase watch time and ad revenue, and provide it feedback such as likes, views, etc to help determine future decisions. Really complex stuff. XD

[@jewe37]

theLuigiFan0007 they ve famously got no clue what it s doing so they just cant xD i guess it picked up on this video sitting there waiting to publish

[@theLuigiFan0007Productions]

Definitely possible, with the amount of data at it's disposal I'm not surprised at all.

[@sciencecompliance235]

Literally laughed out loud.

[@VoidHalo]

Really? Seems to me the algorithm is about as smart as a brain damaged child.

[@lockonjunkie]

Just an info regarding the usage of chloral hydrate: It's commonly used in the analysis of plant powder drugs, because it causes the powder to swell up and you can see everything better with the microscope

[@evie5375]

"we need to wait for it to cool to around 50-60°C. we don't need a thermometer or anything for this, we just need to wait until it stops hurting to touch it" me cooking

[@Michael.Chapman]

In the pathology bacteriology lab we used a solution of choral hydrate (tinted with a green dye for visibility) to draw lines on agar plates, creating segments and stopping different bacterial species migrating into other segments of the plate.

[@nmr405]

the way he says “agar” and how he “infected” the plates 😂😂😂 microbiologists watching this video bout to bust a blood vessel to get this man to say “inoculated” just once

[@GreenCaulerpa]

mrlaserguy2 Ohh yeah. Can absolutely relate to this. Another thing I have been waiting for is him adding even a little bit of luria broth or just yeast extract but nope. He „infected“ the pure agar plates and smeared them with his fingers as if he was a butcher. This made my inner microbiologist die from a stroke

[@Toebesjoer]

When he didn't flip the plates when the agar had set...reeeeeeeeeee

[@formallydehyde]

@@GreenCaulerpa glad someone else cringed at the "not adding nutrients to the agar" bit lmao

[@GreenCaulerpa]

Alexandra Johnson yeah, that made me cringe so hard 😅

[@SteffiMarshall]

All wrong!! Lmao!

[@AureaPersona]

This was the first multi step organic synthesis I ever performed. :) memories It sublimes at room temperature and makes beautiful crystals that smells like camphor.

[@mortlet5180]

AureaPersona; But this was a single step reaction though?

[@AureaPersona]

The 17 year old me did not own any chloroform, so I had to figure out how to do the haloform reaction first.

[@Timothy656]

Many reactions that are recorded as a single reaction equation are in fact made up of a series of elementary steps.

[@turboretard9555]

Did you eat it

[@dytractiate]

how'd the high feel?

[@scarakus]

Shit, I thought you were gonna test it's hypnotic properties...

[@askhowiknow5527]

“Hypnotic sedative” and “preservative” doesn’t sound like a good combination.

[@tammy7087]

My father had no background experience in chemistry nor a formal education yet he could synthesize the perfect hypnotic sedative. He used corn, sugar, yeast, water and various other fruits or grains. Once he ran them through a device he called "the dream machine" he could hypnotize or sedate anyone with the moonshine.

[@sixseven404]

Haha awesome, very cool dad. Cheers to him 🍻

[@bobdehuisbaas1]

making the stuff yourself and then proving its efectiveness makes for a pretty damn cool video!

[@PostProteusKitten]

These videos are so interesting, and chemistry is so far removed from my daily concerns that I find it relaxing. Not to mention the calm presentation. Thanks to this, I watch NileRed to help me sleep. I guess you can say this video is also a Hypnotic Sedative.

[@slightlyzack9404]

Underrated joke lol

[@FilbieTron]

As someone who used to work in a bio lab with lots of Petri dishes, I really had a visceral reaction to Nile rubbing his fingers all over the plates lol

[@YvngKrishna]

Felt that pain as a mycologist, last year had someone who was taking care of my pets while i was out of town touch a few mycelium samples i had lying around and they all got contaminated

[@ThijsKops]

@nilered your agar plates contain to little nutrients for bacteria, using some peptone or beefbroth gives better (faster) results.

[@chuckcrunch1]

i found adding a 1cm cube of ham( for 6 dishes ) wile heat the agar(remove ham after heating ) works well for stinky arm pit and foot bacteria .

[@NileRed]

Yeah I figured. Ill try that next time

[@lithiumlight6128]

or just add sugar or something like that to agar ?

[@ericmueller6836]

chuckcrunch1 Thats a bit better than heading to the butcher for the ingredients to make Brain-Heart Infusion.

[@plazmotech5969]

Not really. Agar is itself a medium for growth. It's not hard at all to get bacterial and fungal colonies on properly dosed agar.

[@jj-mcgreezies]

thank you for including the mechanism i love when it gets technical

[@nash6293]

This reminds me of all the hours my small class and I spent in the organic chem lab. Looking back on it, those times were a great bonding experience with future professionals in the science field.

[@supersungal2]

And then there's me, a film student, who watches these just for funzies and because his voice is nice to listen to

[@Midaspl]

0:50 - chlorobutanol's and chloral hydrate's structures look like they want to have kids together, lol.

[@OsirusHandle]

Nile, Is there any chance you could do a series on manafacturing anti-biotics like Pencillin? Its a drug that seems like it would be extremely useful to manafacture in some kind of survival situation.

[@gravyboatcaptain2292]

I am also interested in how medicine is created

[@JohnSmith-tz4on]

Thirded

[@jordanwardan7588]

has penicillin been synthesized? genuine question

[@OsirusHandle]

@@jordanwardan7588 yes but most is produced via processing grown mould

[@VoidHalo]

In an RI lecture I saw, they demonstrated antibiotics by soaking a small piece of paper in a solution of the compound and put it in the middle of the petri dish. It makes for a really striking contrast.

[@kkanakis1957]

Yes, Today I'll be showing you how to synthesize Illudium Q-36, and make into a, Explosive Space Modulator.....(credits & thanks to Marvin M. for this segment).

[@ArdyneusTheGod]

I completed on College Chemistry course this year. I love science because it always gives me knowledge that explains why and how things exist. I learned a lot in Chemistry class.

[@Morkmonkey69]

NileRed, I wanted to thank you for how much you have taught me in consideration to how unavailable this knowledge seems to be. You have helped me immensely and I cannot thank you enough. They don't even teach you what an Erlenmeyer flask is in chemistry.

[@PeterJavi]

"I made chloroform." - NileRed 2017 I'm not judging though, but I would be interested in buying large quantities of the blue crystals you're making.

[@siv108]

PJ Vis hahahahahahahahahahahahahahaha because the meth! the meth in- hahahaha oh wow - you made a breaking bad reference - oh wow. So good. Soooo good. I hope you feel good about yourself now.

[@PeterJavi]

Not really going for a breaking bad reference, rather curious if he could and or would show such a process.

[@siv108]

PJ Vis if you think chloroform in context of organic synthesis is funny, or teaching others to make meth online is a good idea, you really shouldn't even be allowed around organic solvents, let alone thinking about syntheses

[@rdizzy1]

Anyone that wants to make meth can find out how to do so incredibly easy, one person showing others how to do it won't make a difference. Most average people won't try to make it regardless if they know how.

[@siv108]

rdizzy1 right that's kinda my point, if you're too dumb to Google this stuff, and are instead going to urge nilered to hold your hand & risk a ban, you're an idiot who needs new interests

[@venirl3407]

I'm an undergrad Microbiologist, and I love these chemistry videos! They make my organic chemistry class so much more engaging. For the agar plates, you can actually just add a small amount of chlorobutanol in a small pellet and you'll get something called a zone of inhibition which you can actually use to measure how toxic something is to an organism. It might not be as helpful since you don't have a single culture of microbes but would still be cool to look at. Keep up the good work, you're making me want to switch to Biochemistry

[@BiologyIsHot]

You're supposed to incubate plates upsidedown.

[@markobulic6255]

Please explore more antibiotic compounds like penicilin or azitromicyn. :D

[@BadDadio]

NileRed videos often make me wish I chose a different profession. Keep them interesting; curiosity keeps us going.

[@greensheen8759]

The power of seed crystals! Reminds me of the times I've had stuff suddenly violently boil the moment I touch it lol

[@souravzzz]

Especially enjoyed the anti-microbial test. Please do more similar tests of the chemicals you synthesize!

[@lah-tee5412]

I have no idea what just happened but I know I’m super excited 😆 I think you make me wanna be a chemist when I grow up!

[@andrewsmart2949]

you explain chemistry so well nilered

[@AtomicLobster69]

"Chloroform recipe in description" *Me skipping this video and going straight to that one*

[@Sue_Me_Too]

Turns out it's just super easy to make

[@dukem8774]

Tldr?

[@jarrod0987]

Wow, the stuff you can find on KZbin.

[@hajdurobert6962]

NileRed, when will you synthesize caffeine? I'm really looking forward to it.

[@mkesenheimer]

To be fair, if you added this amount of Acetone to your test dish, it would probably be a disinfectant, too.

[@roselee9063]

These videos help me fall asleep, thank youuuu. Your voice is relaxing and these videos are interesting but calming

[@mortlet5180]

Hey Nile, great job with this video! I ESPECIALLY liked the way you dealt with the oil. Even if you lose out on yield, I always appreciate it when someone takes the time to properly purify a compound, so thanks a lot for doing that! PS. Are you able to do melting point analysis with your current setup, without it being to much of a hassle? If so, it might be worth while to check the mp at the end of a synthesis, just to make sure that the reaction didn't take a completely different pathway or something? (Not really applicable to this synthesis; I was just wondering in general)

[@drakoz254]

Nile I love your videos! I googled this and I found something super fucking cool. Apparently it makes sea urchins start the process of birth without fertilization. Thought I'd share.

[@NileRed]

I totally forgot to talk about that!

[@drakoz254]

I really don't understand any of the process involved, but that is just incredibly interesting to me. have a nice day!

[@mafiainsane7198]

Eloquen that's really interesting. Shit like this just amazes me, crazy how things work.

[@2Cerealbox]

I'm amazed KZbin hasn't taken this channel down yet.

[@kenbuster3524]

That's because he is CIA

[@VoidHalo]

I just noticed the other day that some eardrops I have cotain 5% chlorobutanol. It also has para and ortho-dichlorobenzene, so it reeks like burnt rubber. The label lists it as chlorbutal, but I confirmed it's chlorobutanol.

[@nicholaspoole321]

Thanks my neighbor never knew what happened

[@JuryDutySummons]

I like the follow-up experiment.

[@mrnoob7570]

Today I performed this practical in my college lab

[@joshuapatrick682]

He does know this is a controlled substance he’s showing us how to make from relatively easy to get household chemicals?

[@jhyland87]

I just replicated this at home. I'm a novice chemist with little experience (though im building it up), so i figured this would be worth a try, and you're certainly correct when you said it would be an easy synthesis. Thanks for the instructional video! (Which is excellent quality as well)

[@rumeunner3245]

12:57 the plate on the left reminds me of the moon.

[@Livingreciever]

You are a genius when it comes to chemistry, You know so much! Why didnt you use salt in the ice bath to reduce the temp further? lol

[@Itsbuckjames]

Can you do some experiments with ergot fungus? It would be pretty interesting!

[@Sdnaurs]

I can vote on that one, specifically ergotamine tartarate in large quantities ahahaha

[@0v_x0]

are people tryna get him audited by the DEA lol

[@KGB.83]

😆 🤣 😂

[@Archiekunst]

This is very interesting NileRed. The oil formation is what is known as Liquid-Liquid Phase Separation while the crystallization is a Liquid-Solid Phase Separation. Substances that do both LLPS and LSPS in similar conditions are very rare. Proteins are an example, they can form aggregates, crystals or droplets. Perhaps you can explore this property of chlorobutanol and discuss why it solidifies at a sudden temperature drop while 'oils out' other times?

[@de6hl]

After binging Nilered videos for a week, I feel like I'm on some kind of list somewhere

[@StephenGillie]

This reaction is like unscrewing a retaining bolt, screwing on a whole 'nother section, then reattaching the retaining bolt.

[@ZASurvivalist]

*Bill Cosby has entered the chat*

[@ScaryRevenant]

LMFAO both comments

[@meshakvb6431]

@Johnston Steiner Bill Clinton left with Epstein.

[@hughsnuts7318]

@@meshakvb6431 Prince Andrew denied all memory of this video

[@usern4metak3ns]

all the white people in the shadow government endorse using this product...

[@mark6302]

looool

[@ceeclue7038]

Cool! Loving organic chemistry .

[@Mysucculentchinesemeal]

O Chem is the best Chem!

[@kurama5485]

Hello Nile Red, good work as always :) If chlorobutanol tends to sublimate, it may be a good idea to purify it by sublimation instead of recrystallization, to increase the final yield (there's no solvent that has to be evaporated away and there's no loss of product), am I wrong?

[@MRblazedBEANS]

Daniele Mirante good idea!

[@NileRed]

That might be an idea. I just dont have a proper sublimation (cold finger) setup, so I felt recryst was easier. But yeah, it is definitely a viable and probably better option

[@kurama5485]

NileRed yeah, I understand, I need so much glassware that I haven't got to prepare so many compounds I'd like to prepare! Anyway, thank you for the answer :)

[@GoldleafScientific]

email your shipping address to [e-mail]. Ill send you a bunch of free glassware

[@kurama5485]

Goldleaf Scientific Are you sure? I'm from Italy ahahaha

[@cegda5886]

Add some nutrient to your agar and you'll see growth much faster. 3-6% is usually ideal. It can be anything from light malt extract, to brown rice flour, to dog food

[@thomasgarbe8354]

interesting reaction leading two common solvents to a solid

[@The_Great_Gernzo]

11:25 @Nilered you should really blur this image with your fingerprints, thats valuable info people are willing to steal and sell.

[@usuckeggs264]

Chloroform evaporates rly fast you might’ve lost a lot of it during that mixing

[@herrbrahms]

"Between putting it in and taking it out, I lost 6.2 grams." TWHS

[@StarsForward]

How chemists talk dirty

[@lanam4490]

When I graduated from high school two years ago we had to do a research project/paper for every class. For my chem class I ended up making chlorobutanol and testing it on agar plates and I used this video to help me do the procedure, so thank you Nigel for helping me graduate! My percent yield was terrible though, 5.7%, but given that I didn't have any of this professional equipment I'm just glad it worked

[@jhyland87]

This was my first synthesis done as an amateur chemist hobbyist - inspired by this video. Thanks NR!

[@TheDarquon]

"Hey Chriss(whistle)s ;_) Hey mister Herbert :-) " I have been working on an old sedative, can you tell me if this rag smells like chloroform?"

[@StephenGillie]

Wondering if you'd cover Chloral Hydrate. Some notable users of this sedative include Freidrich Nietzche, Marilyn Monroe, and Anna Nicole Smith.

[@0v_x0]

implicated in the death of marylin monroe innit. drug cocktail but it might've been phenobarbital. or methaquaalone. can't remember offhand. either two of those could do it. or too much of any.

[@jjbulik]

"Chloroform is hard to get a hold of....so I made some" 😂 dude be dangerous but useful

[@Sue_Me_Too]

Turns out it's just super easy to make

[@misham6547]

Its a solvent so it has legitimate uses

[@Sue_Me_Too]

@@misham6547 Many solvents have recreational uses as well.

[@James-cb7nb]

Don't worry he only chloroforms people who use weird filters

[@xenon3759]

Watching these videos is inspiring me to start actually trying to learn about chemistry. Idk if or when I'll do it on my own time but I'm thinking about taking some kind of chemistry class when I go to college. High school was never good at making topics interesting to me, and when I started learning about some of these topics after graduation and on my own time I notice it's much easier to take an interest in it because it's not restricted to what you have to learn in school. And after doing this I feel like it'll be much easier to not feel bored or uninterested in a classroom setting

[@jamesmetzler2031]

I think I'll try this recipe tomorrow. Sounds easy enough and I already have all the ingredients in my pantry. OMG, are you serious? How many chemists watch KZbin videos looking for formulas? At any rate, sounds illegal as hell.

[@historyhunter5215]

Hold on a sec, brb, some one is pounding on my door screaming something about a search warrant...

[@thedude7726]

I wish I knew what was going on. you have some cool bongs bro.

[@finnegannn]

1:39 The chloroform bottle isn’t suspicious *at all*

[@waldenaosullivan3227]

It's wrapped that way because it evaporates very very quickly.

[@Jp-ue8xz]

"Between putting it in and taking it out, I lost 6.2 grams" - NileRed

[@sir9integra9jr]

i'm a microbiologist, i just about fainted when he opened the plate and put his fingers all over it

[@sir9integra9jr]

Also, I know this video is a year old but if you ever want to test antimicrobial properties in the future, I can send you a recipe for LB plates that bacteria will grow decent colonies on in 24 hours.

[@mizuki4002]

I know this comment is also a year old but I want the recipe.

[@ellomdian]

Agar? When did Nile start doing Bio?!? :)

[@SolitudeCS]

no one can hear aeiou in space

[@vplusultra]

ruskiturbo John Madden can.

[@luisp.3788]

@@vplusultra is this a reference to vinny and chat experiencing hell pour out of john madden's mouth and all the players turning into angels

[@invious147]

you should do more edible chem

[@NileRed]

I will! Wintergreen and capsaicinoids are going to happen eventually.

[@guillaumeproux7877]

I never had any interest of chemistry but you really explain things in a way that 10 years of education (up to Uni year 2) never managed to get through. I wish you were a teacher in my UNI! Thanks for showing the antifungal anti bacterial effect... it is very interesting!

[@ShOOtinGliTteR]

This was so good.

[@rueporter2253]

Wow, this is really great stuff. I used to be prescribed that solution, choral hydrate. It’s kinda good. Not as good as a benzodiazepine, and it’s effectiveness wears off as you build a tolerance rather swiftly. Again, this was perfect 👌🏻 to teach. Thank you. edit, and then I looked at your channel....🤯😝👍🏻I’m totally subscribed.

[@RedcoatsReturn]

Great videos! Long live chemistry! By the way, try using a seed crystal to avoid oiling.

[@glor3na]

no big deal just makes his own chloroform for fun :p

[@sundance8623]

I wished I had. A gf :/

[@l0k048]

@@sundance8623 bruh

[@raibeart1955]

Just make some bread with damp wheat. That sent almost all of a small village in France mad.

[@lindawolffkashmir2768]

Now synthesize out triclosan.

[@XeonProductions]

Today we're going to make a hypnotic sedative: Yay!, but it's toxic to the liver: nooooooooooooooooo.