Just what I needed. Concise, accurate, and clear. Thanks for the vid. :)
@hussainbiology5 жыл бұрын
Thanks brother for appreciation..... Really Glad to know that it helps.😊😊
@vishk123 Жыл бұрын
All your videos are phosphorylating my work!
@hussainbiology Жыл бұрын
that is what how feedback should be..... thanks
@samuelboatengtakyi7070 Жыл бұрын
Every detail and interchangeable word used in publications that make them confusing to follow is excellently captured and explained in the video. This lecture is more than 5-⭐rating. Thank you so much!
@hussainbiology Жыл бұрын
Thanks for appreciation...Glad it helps
@DebateEnjoyer6665 жыл бұрын
I've watched a few of your videos now. They are so much better than our revision slides... Thank you! Keep up the good work
@hussainbiology5 жыл бұрын
Thanks Emmanuel for appreciation.... Glad to know that it helps
@jogeshkumarsharma29695 жыл бұрын
Damn🔥🔥there is so much information in just less than 7 mins ...amazing thankyou🙏
@hussainbiology5 жыл бұрын
Thanks Jogesh for appreciation.. Really Glad to know that it helps
@xrcc2022 жыл бұрын
I'm getting so much help by watching your video lectures for the preparation of my college studies. Thank you so much Sir for all these because it not only makes us feel interested towards the topic but also makes it way easier.
@hussainbiology2 жыл бұрын
thanks for appreciation..Glad it helps ✌️
@KILIMANJARO30105 жыл бұрын
Now I don't have to read through a boring chapter. Thank you!!!
@hussainbiology5 жыл бұрын
thanks Madsen for appreciation...Glad to know that it helps
@eyadbazmawi80052 жыл бұрын
you're keeping me alive in medical school. Thank you so much ♥️
@hussainbiology2 жыл бұрын
thanks Eyad for appreciation.... Gald it helps.... Do share it
@arah23683 жыл бұрын
It's hard to find niche channels like this for medical sciences. You are filling the biochemical niche very well ❤️😁
@hussainbiology3 жыл бұрын
thanks for appreciation ✌️✌️
@reneesilva83085 жыл бұрын
It's amazing how I was reading about Polycystic Kidney Disease, and how this pathway produced the entire physiopathology, or at least part of it. You save my life men, u are amazing.
@hussainbiology5 жыл бұрын
thanks dear for appreciation...Glad to know that it helps
@l.fsader60214 жыл бұрын
Everything is connected
@SorrowFullGaming5 жыл бұрын
thank you so much, this helped me so much for my exam tomorrow! I would've failed without you
@hussainbiology5 жыл бұрын
You are welcome Jose....Keep sharing and supporting and thanks for appreciation...
@SorrowFullGaming5 жыл бұрын
Hussain Biology definitely will share and support!
@willj4ck5 жыл бұрын
thanks for the explanation. I've seen Neurofibromatosis disease mechanism today and learned about the neurofibromin protein (NF1 gene) but couldn't understand its function at first...now I see that neurofibromin is GAP that stops MAPK/ERK signaling pathway. thanks a lot
@hussainbiology5 жыл бұрын
Thanks Will for appreciation....Glad to know that it helps
@malvikabisht92885 жыл бұрын
THANK YOU SO MUCH . THIS WAS EXPLAINED BETTER THAN IN MY LECTURE
@hussainbiology5 жыл бұрын
Thanks for appreciation.. Glad to know that it helps
@emmanuelappiahtawiah92614 жыл бұрын
Thanks a lot, Sir. This couldn't be taught any easier!
@sushicat16669 ай бұрын
Thank you very much! helping me through my masters
@hussainbiology9 ай бұрын
Happy to help!
@TheAlcoholicNun5 жыл бұрын
THANK YOU. only clear and detailed video out there on this process
@hussainbiology5 жыл бұрын
Thanks Daniel for appreciation...Glad to know that it helps...
@reallwestron8 ай бұрын
شكرا على هذا الفيديو الجميل بارك بك الله
@hussainbiology8 ай бұрын
Alhamdulillah......✌️✌️
@milenasarkowicz3080 Жыл бұрын
Great video that puts everything into place! Thank you!
@hussainbiology Жыл бұрын
thanks for appreciation..Glad it helps ✌️
@Kelly-jh6dy4 ай бұрын
God bless you!
@hussainbiology2 ай бұрын
thanks
@koreanshots67165 жыл бұрын
You are simply awesome..thank u
@hussainbiology5 жыл бұрын
Thanks Sobia for appreciation.... Really Glad to know that....Keep sharing and supporting
@ankansarkarnjs97503 жыл бұрын
You make such pathways so easy. Thanks a lot hussain.
@hussainbiology3 жыл бұрын
My pleasure 😊
@xrcc2022 жыл бұрын
All the videos by Sabbir Sir regarding cell and molecular biology are just world-class 💯✅
@laitanwulf5 жыл бұрын
i love this, i love you, thank you
@hussainbiology5 жыл бұрын
Thanks Laitan for appreciation....Glad to know that it helps....Keep sharing and supporting
@aswanirael52553 жыл бұрын
Thank you sir, may almighty God add you more knowledge
@hussainbiology3 жыл бұрын
Thanks for appreciation...Keep sharing and supporting ✌️
@sanakausar32294 жыл бұрын
Just by seeing ur video for few minutes one can understand whole concept easily... Thank u..🙂make more videos on csir ugc base hot topics
@hussainbiology4 жыл бұрын
thanks Sana for appreciation..Glad to know that it helps ✌️
@JitenderKumar-tm2kb3 жыл бұрын
Ur smart and hard work make things easy for us .. thank u so much
@hussainbiology3 жыл бұрын
thanks for appreciation
@ek34513 жыл бұрын
This pathway seemed dauntingly complicated until I watched this video... Great explanation, even comprehensible to a high schooler like me haha
@hussainbiology3 жыл бұрын
thanks Erik for appreciation...Glad it helps
@minaltaunk88884 жыл бұрын
You are a true gem keep it up
@anjanasaji65573 жыл бұрын
Very nyz class...👍 everything is clear,and easy to study.. Thank you
@hussainbiology3 жыл бұрын
most welcome
@ranimealtaweel37323 жыл бұрын
Just woww But I would like to give a note : The Ras is active only when it is attached to the membrane. When Ras is in a free formule in the cytosol, then it is inactive. It is just a remarque. Thanks for all from France 😁✌🏻
@hussainbiology3 жыл бұрын
thanks for ur feedback .. ✌️✌️✌️ would love this add it on my new signalling pathways...
@ranimealtaweel37323 жыл бұрын
@@hussainbiology yes and just keep doing more videos. Ihave a question, would you make some video on optical physic ? It seems complicated and it is in medical program for the first year Any way thank you for all that you do !
@anchalthakur8668 Жыл бұрын
Thanksu so much sir to make video on this topic. I can readily understand this mapk pathway.
@hussainbiology Жыл бұрын
most welcome... thanks for appreciation....
@gayatridas4896 Жыл бұрын
Thank you so much 🥺
@hussainbiology Жыл бұрын
You’re welcome 😊
@hodophile19994 жыл бұрын
Nice video sir it helped me a lot
@hussainbiology4 жыл бұрын
thanks for appreciation
@nil74253 жыл бұрын
🔥Excellently expressed sir. Thank you so much.
@aimnhaqim17 күн бұрын
thanks a lot u really help me understand this topic very well 😊
@hussainbiology17 күн бұрын
thanks for appreciation..Glad it helps
@harunpatel3 жыл бұрын
GReat ..its excellent video
@hussainbiology3 жыл бұрын
thanks for appreciation
@palshah35093 жыл бұрын
Great video completely cleared my concept thank you 🙏
@olaleyeolutunde2 жыл бұрын
Thank you.
@yasinyildirim972 жыл бұрын
Amazing explanation. Couldn’t thank you enough!
@biologicalresearch58364 жыл бұрын
No words hussain shab. Panun kashur boiy 😜
@hussainbiology4 жыл бұрын
barabar boi.....❤️❤️
@tanusharma92715 жыл бұрын
Tnk u sir for such a perfect video lecture..
@hussainbiology5 жыл бұрын
Thanks Tanu for appreciation.... glad to know that it helps
@nifatjan74585 жыл бұрын
After reading 4 tym. ...wz nt able to get it....Sir u made it 8 once....👌👌👌👌thnx a lot
@hussainbiology5 жыл бұрын
thanks Nifat for appreciation...Glad to know that it helps....
@zainababdelaal83977 ай бұрын
Thank u soo much for all ur effort ... ❤
@sidipyrex7861 Жыл бұрын
جزاك الله خيراً ❤
@pesmoboyt7773 жыл бұрын
Wow amazing.. Just I wanted things.. Are you a medical student? Keep going man.. Iam a biotechnology students.. It's really helpful..New subscriber ❤️
@hussainbiology3 жыл бұрын
thanks buddy for appreciation..Glad it helps
@sreenivasshenoy7295 жыл бұрын
Hi, Sir! Its really very good video and clearly understandable. So thankyou very much... I have a suggestion that the subtitles should be error free.
@hussainbiology5 жыл бұрын
Thanks for appreciation...Glad to know that it helps... And surely i will be adding accurate subtitles Shortly
@ashb61364 жыл бұрын
I really liked it man.thanks
@paramitadas17564 жыл бұрын
u know , you r GOD. amazingly nice. u saved me .
@hussainbiology4 жыл бұрын
too much for me...☺️☺️ overwhelmed really.... Thank God He created me to make these lectures and make ur work easier...✌️✌️
@user-dd6ym7nr9r4 жыл бұрын
Perfect video 🌹🌹thank you
@hussainbiology4 жыл бұрын
thanks for appreciation... Glad to know that it helps ✌️
@olivia62044 жыл бұрын
Thank you soooo much !
@hussainbiology4 жыл бұрын
thanks for appreciation..Glad to know that it helps
@shafatfarooq69034 жыл бұрын
Very well explained 👍
@hussainbiology4 жыл бұрын
thanks for appreciation...Glad to know that it helps ✌️
@matskessel54635 жыл бұрын
Perfect man!!
@hussainbiology5 жыл бұрын
thanks buddy for appreciation
@milesofdavis285 жыл бұрын
I like this video, but Ras does not phosphorylate Raf. Instead, it binds it, and that is what activates it. Most cell biology textbooks like Molecular Biology of the Cell or Lodish Molecular Cell Biology explain it this way with cited experimental assays as evidence.
@l.fsader60214 жыл бұрын
milesofdavis28 hace you gone into the lab and tested yourself?
@pianomelody33126 жыл бұрын
thank u sir....itz very helpful...keep making such awsome videos..
@hussainbiology6 жыл бұрын
Thanks buddy....
@yuktasansare7535 Жыл бұрын
Ras protein binds to GTP and ERK binds to ATP, what is reason for this difference?
@jawadnawaznawaz87936 жыл бұрын
Very good
@asap0003 жыл бұрын
Thanks alot..
@suzuka96542 жыл бұрын
Very good representation 👌👌
@zainiiBee5 жыл бұрын
cleared my concepts.. thank you
@hussainbiology5 жыл бұрын
Thanks Zainab for appreciation..Glad to know that it helps.
@blackbeard32853 жыл бұрын
I'd like to thank you for your excellent explanation! I've a question though, is this pathway similar to the RAS map kinase pathway? Or is it different? Thanks a bunch 😃
@hussainbiology3 жыл бұрын
yeah very much similar
@blackbeard32853 жыл бұрын
@@hussainbiology thanks. Got the clear idea 😃
@skyedad97113 жыл бұрын
Just wondering if the dimerisation of the receptor is due to cross-phosphorylation or auto-phosphorylation ?
@oculosify4 жыл бұрын
hello, there is something I dind't understand... does this pathway, just like AKT pathway and STAT pathway, happen in all immune cells, such as tissue-resident cytotoxic T cells (IE-CTL)?
@vandnakapil8895 жыл бұрын
Thnkuuu sir ... beautifully explained...
@hussainbiology5 жыл бұрын
Thanks Vandna for appreciation.... Glad to know that it helps
@adilanessi72485 жыл бұрын
Thank you sir
@hussainbiology5 жыл бұрын
You are welcome....Gald to know that it helps
@ramchandrasuthar28486 жыл бұрын
Nice analysis bhai
@papiyabiswas34775 жыл бұрын
hmm,,onk valo poriskar holo ebr byapar ta
@hussainbiology5 жыл бұрын
Couldn't understand???
@papiyabiswas34775 жыл бұрын
No no,I really understand this pathway clearly by your video
@hussainbiology5 жыл бұрын
@@papiyabiswas3477 Thanks Papiya for appreciation...Dhan'yabāda
@marianaelisaramirezmitre6858 Жыл бұрын
ERK does not traslocates to the nucleus?
@bhatjas18205 жыл бұрын
thanku sir... nice video... great efforts.. sir have a confusion that raf is not phosphorylated... it is only kinase which is not phosphorylated, recruted by Ras..
@pirate22555 жыл бұрын
You are correct. Recruitment of RAF by RAS actually facilitates the dephosporylation of ser259 which results in the disruption of the interaction between RAF and inhibitory 14-3-3 proteins, therefore activating RAF. RAS also facilitates RAF activation by driving RAF dimerizaiton.
@l.fsader60214 жыл бұрын
Damien Rasmussen no bro. You literally just said the recruitment of raf activates raf. Look at your reasoning
@lj70194 жыл бұрын
Good explanation but please slow down
@hussainbiology4 жыл бұрын
Surely i will
@tanu64643 жыл бұрын
😊😊😊😊
@fathmanawaz50256 жыл бұрын
Nice sir
@hussainbiology6 жыл бұрын
Thanks Fathma for appreciation.....Keep supporting 😊
@surendrasaini90572 жыл бұрын
How to erk phosphorylat RTK
@villevilkki36252 жыл бұрын
KInda of topic, but if you want to be precise with your drawings please draw the nuclear membrane with four layers of phospholipids, not like cell membrane that has only two layers.
@hussainbiology2 жыл бұрын
Thanks for your feedback..... I will definitely consider making that
@rajeshbhardwaj2983 жыл бұрын
Excellent video Hussain. I think one only important thing missing from the picture @3:12 is what phosphorylates RAF. From another video (kzbin.info/www/bejne/p52ZY56DgJh1qK8) what I learnt is that a scaffolding protein binds RAF (which is bound to Ras) as well as Src kinase to form a complex. The scaffolding protein increases the local concentration of Src and RAF allowing them to interact. Src then phosphorylates RAF to fully activate it. I just subscribed your channel to learn more basic biology. Many thanks as you are doing a great job!
@hussainbiology3 жыл бұрын
thanks for appreciation and ur feedback is noted
@user-yv2yj1wo9q4 жыл бұрын
Who is STAT stimulate oct4
@subhamchowdhury66554 жыл бұрын
Need new vedio
@weesaikim60903 жыл бұрын
Muacks ty
@hussainbiology3 жыл бұрын
Thanks for appreciation
@samirawani84272 жыл бұрын
Are u a kashmiri by any chance
@hussainbiology2 жыл бұрын
Yes sir .. I am
@matskessel54635 жыл бұрын
Do you have a video (if not can you make one?) on tor signalling?
@hussainbiology5 жыл бұрын
mTOR video will be available very soon.....
@iqrazulfiqar59454 жыл бұрын
WOW
@hussainbiology4 жыл бұрын
thanks for appreciation..glad to know that it helps