Mechanisms and secrets of Alzheimer's disease: exploring the brain

[@1021memo]

I have never in my life seen a medical video that is good as yours, truly professional.

[@TheCornbeefsoup]

Beautiful animation. I wish more biological videos were made like this.

[@ghettrsc8764]

TheCornbeefsoup exactly

[@iloffys7798]

The voice and the animations are just perfect

[@nikkiwillis1122]

*Our Mom Alzheimer's and dementia story:* *kzbin.info/www/bejne/d3PSgWhtr7l5eck*

[@savankate7239]

. When I see this post I remember Dr. Osemuahu. He really made me believe in him so much. by healing me months ago with his herbal treatment from Alzheimer disease. I really appreciate you very much and he is able to cure you from any sickness and he also cured my cousin from Ischemic heart disease thanks to him ...if you have any diseases let me know so I can link you up with him ..

[@3joewj]

Insulin degrading enzyme is what clears the plaques but if you have too much insulin...that enzyme is sufficient only in degrading insulin and allows the plaques to build. So increasing insulin sensitivity would be the goal...freeing the enzyme to complete its other functions.

[@me55n]

The best medical video I've ever seen ....

[@戴彌生]

When I wanna introduce Alzheimer's disease to my friends or other people, I recommend them come to this video. It's a wonderful material suitable for all people even they aren't researchers in this field.

[@CMDR_John_Crichton]

My granddad is currently in the later stages of this. I've come to accept it as inevitable, but its still hard, partially because I never fully understood it at the neurological level. Thank you for uploading this.

[@najlaa6308]

A beautiful animation to summarise what's happening in Alzheimer..

[@ElijahPlaysTennis]

For patients and caregivers, this is the most insightful and well-accessible video I've watched about the pathological bases of dementia. There is now increasing evidence that tau is present at sub-detection thresholds before amyloid though. Hopefully with the development of in vivo tau imaging markers in the next couple of years, we will all get a better grasp of the temporal sequence.

[@yodaydyxz1752]

Also this is the best animation for AD on YT.Don't even waste your time trying to look for more. Thanks for sharing LECMA.

[@keishahouston1943]

Yess try do our best to make it into a understanable way our ways in Scenice so everyone can enjoy to

[@dr.salmanriaz1468]

What a clip? Completely flawless... Awesome.. Awesome awesome and thousands of awesome

[@SMGAPR8]

This is the one time that I embrace technology, a deeper understanding, very educational and a compassion for the mysteries of human mind, body and soul, superb 🙏

[@zenzaiL4D]

By far the best presentation of AD I have seen. The way you integrated the beautiful music with the animation, together with the narrative made it beautiful to watch. Thank you.

[@kvvful]

real great animation and explanation even an alzheimer patient could understand

[@255jayjay]

The best medical video I've ever came across.

[@2000Betelgeuse]

Great video, it makes it easy to understand

[@OswaldDigestiveClinic]

If you liked this video, you may also want to know that it's estimated that 45 million out of the 328 million people in the U.S. will have Alzheimers! That's 13.7%!!

[@Usemefortrending2024]

amazing and thank you!

[@polysom6345]

I freaking swear they need to make videos like this for A&P, diseases, and medication effects. I would pay good $$$ for these!!!! Videos like this are the only way I can truly understand the process of things!!!

[@rebeccatemi9909]

Very good video summarizing the neuropathogenesis of AD, however, I think it's essential to highlight the hyperphosphorylation of tau proteins

[@ng8giga]

can you explain what you mean in simple terms?

[@coline9179]

so far the BEST animation of pathophysiology Ive seen here on youtube!Thumbs up!:)

[@VasculexAO]

This is an excellent explanation of how the brain changes occur and Alzheimer's disease I would urge you to watch it several times because it has many many features that are important to understand as far as the details of how the disease happens. One addition that I would like to add is that most of these changes are actually initiated by the autoimmune process in the brain.

[@scottwilly86]

+Raif Tawakol Inflammatory risk factors seem to promote a number of degenerative conditions. The mutation of the APP gene to those genetically predisposed to Alzheimer's occurs on chromosome 21. The majority of Down's Syndrome occurs because of that extra chromosome on 21. Down's is also up to 5 times more likely to develop Alzheimer's and/or die from other inflammatory responses/autoimmune issues in the body.

[@mashaelalansary3229]

Excellent video. Perfect animation and the music is so soothing. The person narrating is awesome!

[@saahilvij3416]

Amazing video depicting the pathological process, very insightful

[@SuperIndigo2011]

Simple and clear explanation of the disease, thanks!

[@helifynoe9930]

Imagine walking from room to room, but not knowing why you did so when you get to the next room. Being unable to even recognize words as words anymore, but having to read them letter by letter, and even then having to read the sentence over and over to grasp its meaning. No longer knowing how to spell names of family members. Short term memory at times being completely nonfunctional. Suddenly at times having no connection at all to time nor place. Suddenly not recognizing even your own neighbourhood. Unable to recognize quantities greater than two, which makes it almost impossible to take any meds in quantities greater than two. When three or more pills are in the palm of your hand, the quantity is unrecognizable to you. Then eyes taking up to 2 hours to respond to change in light intensity. What makes it even worse, is when the doctors misdiagnose you. What makes it even more unforgivable, is that it was a self diagnosis that provided the correct diagnosis, despite being one step away from being a vegetable. It took me 8 years to fight my way back, to no longer having a body that was as stiff as a 2 by 4, to relearn again, although I never did relearn how to write, other than write my signature.

[@FondationVaincreAlzheimer]

We are really sorry and sad to hear your story, that's why the work of our foundation is so important. If you need any advice, or if you have any questions, contact us via e-mail at [e-mail] or call us at 0142465086. Our scientific director may be able to answer your questions. Kindly

[@mithunraaguld6999]

I am school student and you made my mind just blow you are great with your explanation

[@carmenmperezperez1983]

Excellent!! Easyto follow and to understand.

[@masanamuthu3121]

wht a awesome animation which includes emotional background sounds.........Which tends people to attract more towards ''Psychiatry'''

[@Nyny.1000]

Brilliant way to tie together other alzheimers videos here on KZbin.

[@likemoreal]

This film is very beautiful and easy to know key points of Alzheimer's disease. Thank you!

[@jonBrazilian]

Very good and well explained! gosh, how animations help us understand such a complex phenomenon like that one.. thanks for sharing! :)

[@tcdsvuzjyh123456789]

Thank you so much for the beautiful animation

[@S.Sarajlic]

Thank you! This video made me understand better about AD and it is going to help me to write my thesis! Greetings from Northern Italy.

[@stueykb7784]

Alzheimer's disease/Dementia, is a dreadful and cruel illness,it is currently affecting 850,000 people,And still continues to affect more. I went to visit My Grandmother,after she was diagnosed. Having spoken to her and seeing how she was affected,It distressed me deeply. I am very close to My Gran,So this has hit me hard. The last time I saw her prior to that,never one had it ever crossed My mind that she would ever get struck down by this illness. She has always been a strong woman and such a lovely lady with a kind and generous heart,One of pure gold come to think of it. She would dance around the house waltzing to Andre Rieu , She always made me smile and has always been there when I needed her,Even if it was just on the end of a phone. I do love My Gran,and it is horrible to see a loved one in such a bad way, Knowing that this debilitating illness is ravaging them from the inside. My mother,who is 3rd of my Gran's daughter's , tries to show bravery,But she is hurting and I know it, The thing is it's never their fault or yours, They are in their own world,completely unaware of how their loved ones are affected by seeing them that way, It's just I have heard or seen situations where people caring for an Alzheimer's patient have lost their temper and snapped,and naturally it's very hard to cope in that situation,But the patient is not to blame. I am dreading the day My gran forgets me,Becomes hostile, and is no longer herself indefinitely! ,There isn't a day goes by when she isn't on my mind, And after seeing how she was at the time, I went back to pick up My girlfriend from her Mother's place, and upon embracing her,I sobbed, It hit me so hard, Seeing one of My family no longer themselves. My girlfriend suggested I should organize a charity event. So I'm in the process of it now and pretty much almost done! I want to do everything I can to raise funds and awareness. From 27th May 2017, I will be hosting/performing a live show in aid of Alzheimer's UK charity. I will be working closely with Zoe Baggot who deals with Birmingham's side of things,I will be playing a mixture of Electronica,Dubstep,Chillout,Dance and Industrial,I know it is to early to be sure,and It may not be to everybody's taste,Or too far out for some to travel, and Donate, find time to listen to some of the music on there.There will be a live stream of the event so for those who live across the pond or other places you will get to see it .Also the music i have written for this live performance will be released on an album and 100% royalties are offered out to Alzheimer's UK There will be stunning visuals,Lazers and more, And the live stream will be broadcast globally on You Tube From the Coldstream Pub in Birmingham. I will be doing 3 Events in total to try to raise at least £1000 or over. I know I can't save My Gran,But I can try to save others in the future.

[@malavikapradeep9771]

Very informative video. Thank you so much.

[@OswaldDigestiveClinic]

If you liked this video, you may also want to know that it's estimated that 45 million out of the 328 million people in the U.S. will have Alzheimers! That's 13.7%!!

[@TTerminatorr]

Great video indeed, complexity explained in such simplicity that it gives us a great baseline to build on... Thanks heaps.

[@OswaldDigestiveClinic]

If you found this informative, you might want to know that Dr. Dale Bredesen at Duke University has done a lot of research in Alzheimer’s Disease and looking at possible root causes!

[@santhinatarajansanthinatar9380]

How Awesomatic animation is! Superb

[@TechnicalGuru-pu2ol]

This 6 min video lecture slove my all doughts quickly so thank u so much 😊👌👍👌😊👌👌😊😊😊

[@ankitasamaddar3318]

Very Useful animation and the descriptions are also very helpful..

[@divimsdd93]

Wat a video😍.... Chanceless.... Best visual ever👌👌👌

[@tasneemfahoum5931]

magnificent animation! great job on raising awareness of Alzheimer's !!!!! hope that scientists find a cure for this disease!

[@nikkiwillis1122]

*Our Mom Alzheimer's and dementia story:* *kzbin.info/www/bejne/d3PSgWhtr7l5eck*

[@Isteshhad]

Such a beautiful video that actually made me emotional. Thank you

[@correahanna]

so good and simple understood, with importants informations, thank you

[@Theseniorlist]

Thank you for a wonderful synopsis of this most debilitating disease!

[@aliciaflores5052]

This was a great video. It was very educational and the animation was very detailed.

[@SantoshKumar-tr8gj]

Excellent demonstration n animation

[@angeldavidmolina9338]

Excelente video muy claro y conciso, además súper bien explicado.

[@pranitarai615]

Amazing animated videos... This is the best video that I have ever seen..

[@naqiyahmulachelah5668]

amazing, i would never understand or even interesting to "peek out" about alzheimer if i never watched this. thank you

[@pallavipandey.]

Beautiful animation.and superb explanation

[@MattLenaghan]

What an excellent video - as informative as it is artistically composed. Thank you.

[@lostn65]

my dad died of the disease. Please cure it so no one else and their families has to go through that suffering.

[@terriusthomas1146]

Over 100 drug trials for alzheimers have failed! So at this point alzheimers is basically untreatable and incurable, it's really sad

[@davidornelas195]

My father died from this disease as well... So, I know how you feel!

[@studentxcmu]

Thanks for uploading this video. I am a student. It helps me a lot.

[@missanorajjohnthattil8526]

awesome work on details on both content and graphical explanation

[@saraar5794]

You are creative ,,, very informative 💜

[@mikaelsilva2346]

Que vídeo espetacular ❤️❤️❤️

[@heastner]

Scary, yet great presentation.

[@Nat.0992]

Oh my god! Thank you for this! I was sitting in patho yesterday and I swear I heard crickets! This helps to clear it up so much! Thank you!

[@kaelynnsu3286]

I've read from a few articles that amyloid beta plaques activates an enzyme called kinase and kinase has a phosphate group on itself. The kinase then phosphorylates the Tau protein and that is why Tau protein detaches itself from the microtubule.

[@funnywelshie]

what a fantastic video, brilliant graphics.

[@OswaldDigestiveClinic]

If you liked this video, you may also be interested in research that looks at possible root causes for Alzheimer's! If so, check out the work of Dr. Dale Bredesen. He had a 2018 study in the Journal of Alzheimers Disease & Parkinsonism. The study is titled: "Reversal of Cognitive Decline: 100 patients." It's fascinating stuff!

[@SimonePutzolu]

simply amazing video !!

[@mennasmaowaad3348]

Thanks for the working staff, the most beautiful animation I have ever watched 💓💓

[@valarmathisubramaniam8635]

Excellent visual explanation. Thank to the advancement of Animation

[@imagine.o.universo]

Hello! Can you tell what is the song's name? Thank you!

[@srilakshmidondapati1564]

Superb video for medical students 👌👌

[@santoshkhotlande7213]

The Best & Simple Explanation Ever.... Thank You

[@Lifeholder]

This is fantastic. So glad I watched it.

[@OswaldDigestiveClinic]

If you enjoyed this video, you may also be interested in looking for possible root causes behind Alzheimer's! For this, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

[@shahanaazhameed8443]

U r sooo goood. U r welly educated Dis was very helpful. Do upload such vdos more. Thank u

[@doctorsstudy]

best video... no words to explain how much i like

[@chocolatebar1592]

My Grandma has Lewy body dementia. This video made me feel really sad,as she were quite bad today

[@vipashapmehta]

amazingggg graphics....superb explanation...👍

[@krisanthonysilveira8244]

great great great video .. The graphics ..

[@xinting_study]

Thanks for making this video, it's really informative and good-quality.

[@BBCeiz1993]

Thanks for this video today I hope to continue for other disease by this way of explanation

[@medacademy3918]

Thanks a lot, this is the best video I found about this topic.

[@IMN602]

This is the scariest thing i have ever seen...

[@Gerry363c]

My father died of this. He was 63. I have witnessed every stages of it to his very last breath. Worst experience ever

[@gracelady3092]

I have be dealing with Alzheimer's disease for the past years until i got review online about Dr Favour on KZbin Channel people testifies how they got cured with his herbal medicine, I order the treatment and after taking it for few weeks i totally got cured

[@gracelady3092]

Whatspp him for help

[@gracelady3092]

±14157878148⏯️⏯️⏯?????????

[@mohammedsadekon]

elegant animation, thanq guyz

[@jaymieleesoto7397]

Amazing video.

[@Khanxyz31]

Can u send me such type of animated videos of science

[@OswaldDigestiveClinic]

If you enjoyed this video, you may also want to know that there's been recent research that uses a functional medicine approach to find possible root causes of Alzheimer's Disease!

[@cherryice103]

Great explanation thank you so much

[@OswaldDigestiveClinic]

If you're interested in research that looks at possible root causes for Alzheimer's, check out the work of Dr. Dale Bredesen. He had a 2018 study in the Journal of Alzheimers Disease & Parkinsonism. The study is titled: "Reversal of Cognitive Decline: 100 patients." It's fascinating stuff!

[@Farzaneh72]

you caused I understand clearly... thanks... good job and keep going...

[@frenchmtv]

Very informative, and I enjoyed the music as well. Would like to know the artist.

[@119alias]

Amazing video with sad facts. Thank you.

[@Tura750]

This video is amazing. Thank you so much!

[@OswaldDigestiveClinic]

If you're interested in looking for possible root causes behind Alzheimer's, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

[@bellahilal]

Great animation. It is like that i wish.

[@axelblazefrost2213]

I find it really helpful ! Thanks !

[@binbinky78]

this video is a jewel

[@drmohsingani6954]

Thank You! for such a great video...

[@OrtenciaP1228]

This scientific video is really good. Awesome 3D video, easy to follow and understand. Great job!

[@sysneco]

It's a great educational material.

[@kartikasari5603]

good explanation and nice video

[@lauradigigli7037]

Thank you. Exellent video. Let's hope in sience and resercers❤

[@TheSebasPower]

Great work! thanks for uploading this :)

[@OswaldDigestiveClinic]

If you're interested in looking for possible root causes behind Alzheimer's, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

[@mushtaqnajar8930]

Soo beautifully ...love it totally

[@nikhilnagpure4679]

Awesome ...thanx maam

[@sarat.5496]

Este vídeo es fantástico

[@fayju]

a very helpful and positive video.

[@borderlord]

I saw a Ted Talk where a lady Dr said she got great results with Coconut oil for her husband who was suffering early onset dementia. Any news on that study?

[@shinasshinuus2351]

THAT WAS VERY USE FULL LEARN ABOUT ALZHEIMER DESEAS

[@PhuongNguyen-ks6rq]

this is an amazing video !!!!!

[@sarahwebb5481]

Please can you correct the captions/subtitles, they are incorrect in quite a few places. Cheers