Multiple Myeloma has a low Anion Gap…Ever wonder Why?

[@martyapo]

In the last 6 years, 6 of 8 anion test have come back low (4's and 6's). Over the same time period, chloride has been normal, wbc trend low end of normal, rbc trend high end of normal, and both total protein and albumin are middle of normal. I'm in generally good health but overweight, prediabetic, and a history of kidney stones. Should I be concerned?

[@LittlePurpleBook]

Fantastic video! Isn’t medicine beautiful? Everything in medicine has an explanation.

[@quintonkettell5436]

Question (27M) - I have an anion gap of 2 - Chloride is 109 - normal albumin - Is this worth investigating? Platelets have been steadily dropping since 2019.

[@thewholetruth5473]

A published review found that out of 67,000 calculations of anion gap, a low anion gap was calculated less than 1 percent of the time. Within this small percentage, *_over 90 percent of the results were due to laboratory error in calculating one of the electrolyte values._* Clinical Journal of the American Society of Nephrology 2(1): p. 162-174, January 2007. So settle down.

[@hajaraks3165]

But why the increased M-protien ( which is a cation ) is not added to the equation of unmeasured anion (WHICH INCLUDES DECREASED ALBUMIN) - Unmeasured cation ?

[@unniroshan]

Thanku so much for the video... Explained it simple with basics ❤️

[@MedicosisPerfectionalis]

My pleasure 😇

[@testos2701]

Great and Dandy I think I got it, is that the cure for cancer?

[@TheThomprc]

This is a very interesting video but the details are conveyed way too fast. I'd love to have your script, so I could read and comprehend the information at my pace. Thanks for posting just the same. Bob T.

[@LiveTradesWithJon]

So my anion gap was a 4 which according to the chart on my results is low. My albumin was normal range but I can remember what it was. Would albumin be low if mm was causing the anion gap to be low?

[@Missauthentic716]

I’m not a pathologist but I love this video.

[@MedicosisPerfectionalis]

I appreciate you os much, Stacey! I am a big fan of people who like learning!

[@christyschmelz884]

Anion Gap is 2, chloride is 109, and WBC is 4.5 (has been decreasing for 8 months). Your video answered some questions and now wondering if multiple myeloma is a possibility

[@thewholetruth5473]

Probably you should ask your doctor. When you do, please let us know.

[@thewholetruth5473]

A published review found that out of 67,000 calculations of anion gap, a low anion gap was calculated less than 1 percent of the time. Within this small percentage, *_over 90 percent of the results were due to laboratory error in calculating one of the electrolyte values._* Clinical Journal of the American Society of Nephrology 2(1): p. 162-174, January 2007.

[@christyschmelz884]

Albumin was low as well, doc doesn't think there is a problem.

[@ghaffarkhalili5801]

Mine the same you does your doctor told you anything? Can you share

[@aspencooper8495]

I had on my urine test abnormal below average anion, could that mean that I could have the disease multiple Myeloma? How can you test for this?

[@MedicosisPerfectionalis]

This video is about the serum anion gap. Urine anion gap is a different concept.

[@allaboutmovies4821]

But if that's the case chloride is being used so not increasing burr decreasing

[@MedicosisPerfectionalis]

I am afraid I didn’t understand!

[@arshadhussain8797]

👍...pls make videos on bone marrow transplantation and x rays,ct ,mri, histopathology slides interpretation...thanks

[@MedicosisPerfectionalis]

Thank you so much for letting me know!

[@drketanpatel6401]

First i liked video and then start to watch the video, because i know video will be awesome as always........

[@WhyTheHorseface]

My anion gap is 4. Am I dead?

[@UnviversalLaw33]

So i have normal albumin level but zero anion gap no diagnosis anyone can help

[@thewholetruth5473]

A published review found that out of 67,000 calculations of anion gap, a low anion gap was calculated less than 1 percent of the time. Within this small percentage, *_over 90 percent of the results were due to laboratory error in calculating one of the electrolyte values._* Clinical Journal of the American Society of Nephrology 2(1): p. 162-174, January 2007. Also, maybe you could see a doctor and ask them if you have questions about your lab values. That could probably be at least as helpful as asking random people for medical advice in the KZbin comments. Just saying.

[@knzay]

thanks king

[@MedicosisPerfectionalis]

My pleasure 😇

[@glitterysweet]

Medicine makes sense when YOU teach it. Thank you!

[@MedicosisPerfectionalis]

My pleasure 😇