Pressure-Volume Loops | Compliance | Respiratory Physiology

Pressure-Volume Loops (PV loops) of the lung…Pulmonary compliance (the ratio of the change in volume to change in pressure)…Respiratory Physiology…Pulmonology.
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Thank you so much for amazing content, as always! I had a question about the work of breathing I was hoping you could please answer... in COPD, the resistance is higher so to decrease the work of breathing, I read that they breathe slower and deeper to decrease resistance. Why is that? What is the physics relationship between resistance and velocity of air in lungs (fast breathing versus slow breathing). Thank you so much in advance!

[@penapravoce494]

Excellent video, but it seems that "work of expiration" is not just limited to those with pulmonary problems - indeed, it is the normal function for trained singers! Would love to see you do a video on the pressure-relaxation curve - thanks!

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Thank you for this informative video....can you explain pressure and volume curves of the heart please and thank you

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[@brilliantfuture1841]

Please help In gyton’s book ,I read that (the compliance of the combined lung­thorax system is almost exactly one half that of the lungs alone) .and can’t match it with what you mentioned here about differences between compliance of lungs and lung with chest wall ......... thanks

[@sathsaranigamage4924]

Can you please explain this, sir? In the pressure- volume graph when we consider the gradient as compliance, isn't it higher in 'lungs only' than in 'lungs+ chest wall' ? So, why won't the compliance is higher in ' lungs only' than that of the combined system?

[@Mariamhamwi]

In pneumonectomy, Doesn’t the decrease in intrathoracic pressure cause the diaphragm to pull downwards to accommodate the increase in volume? If not, why not?

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[@HabibiGa1z]

What is the difference between static and dynamic pressure-volume curves?

[@vineetkumarpandey3003]

In inspiration as alveolar volume increases, surfactant density decreases therefore leading to increasing surface tension and thereby lessening compliance. That means that as the curve proceeds the slope should be going down rather than up right ? But then how come the inspiration plot is sloping upwards with increasing inspiratory volume ?

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[@CarlosPires-du3ps]

why in the beginning of expiration the curve is flat?

[@gayathrijinesh3004]

Pleural pressure is same as transpulmonary pressure, just change the sign. This is valid only when intrapulmonary P. is 0, right? That is at the beginning and end of inspiration/expiration.

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Thank you for these great videos and your great explanation..i have a question and i will be very thankful if you answer (i know that surfactant lines the alveoli and it gives it the tendency to get smaller because of its surface tension so why surfactant opposite surface tension ?)

[@MedicosisPerfectionalis]

It’s a fact in physics that surfactant decreases surface tension...Please watch my video on surfactant.

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[@andriavinithalobo5813]

Is relaxation pressure and pressure volume means same?

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Thanks!

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[@pouriaag2094]

hi, nice video. isnt the compliance for lung only, greater than lung + chest wall, since it's slope is greater?

[@johndorian4074]

I think it should be like this: Compliance lung only = Compliance chest wall only (they both should be 2 L / kPa) > Compliance lung + chest wall (which should be 1 L / kPa)

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[@MedicosisPerfectionalis]

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[@johndorian4074]

Medicosis, thank u for this amazing video! At 17:00 tho, I think it should be like this: Compliance lung only = Compliance chest wall only (they both should be 2 L / kPa) > Compliance lung + chest wall (which should be 1 L / kPa) right?

[@sathsaranigamage4924]

Yeah I think so too. That should be true as compliance is the gradient of the pressure- volume curve and clearly it's seen that gradient is lower in the combined system than that of lungs only or chest wall only . And may be the gradients of lung and chest wall are the same.✌

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Excellent explanation

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Can not find pulmonary playlist. Please add link to this video

[@MedicosisPerfectionalis]

Sure! It’s here: Pulmonology kzbin.info/aero/PLYcLrRDaR8_dU-SqmEQlxINRVMmVsqYYO

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[@MsMadamadamada]

how does having no surfactant leads to increased surface tension? mechanism...?

[@MedicosisPerfectionalis]

Great question. The answer is here: Surfactant kzbin.info/www/bejne/eJC7q4h6eNGal8U

[@RogerRoids]

So you're saying the pressure volume loop and flow volume loop are the same thing, right? Thanks!

[@MedicosisPerfectionalis]

No, they are not! 😊

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My pleasure 😇

[@Tanya-dc4ne]

Okay.. We will not confuse with flow volume loop😂

[@MedicosisPerfectionalis]

Awesome 👏

[@omidmobargha3308]

Hi, I am an Italian medical student (pardon for my english) ! I have a question: why did you change the pressure into positive values ? I've searched on lots of sites and I didn't understand why the pressures are positive. Don't we have negative pressures in the lungs at the beginning of inspiration ? The negative pressure is useful in order to let the air flow in the lungs,. Thank you so much !

[@MedicosisPerfectionalis]

Which part of the lecture? Can you give me the timestamp? (i.e. at which minute and second)?

[@omidmobargha3308]

@@MedicosisPerfectionalis thank you for the reply, I've understood it later !

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Does obesity affect plateau pressure?

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[@MedicosisPerfectionalis]

Thanks 🙏 No, I am not.

[@urwahkafeel2982]

Why conpliance is high for expiration?

[@MedicosisPerfectionalis]

Have you watched my video titled “compliance”?

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Thank.you.sir.

[@MedicosisPerfectionalis]

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[@drykMED]

17:05 If lungs alone have a tendency to collapse, so surfactant molecules are accumulating i.e. conc of surfactant increases 11:01, decreased surface tension, increased compliance. So shouldn't the compliance be on higher side for lungs alone??? I think the answer lies in the analogy that lungs alone have increased tendency to collapse, and when placed alone they start collapsing, now if we try to fill the collapsing lung with air, they would resist the filling, so decreased compliance Similarly when chest wall alone is placed, they have a tendency to expand, and they start expanding, and now while expansion when we try to fill the chest wall with air, they take up air very easily and expand even faster, hence highly compliant, so max compliance. Is this the right line of thinking plzz explain???

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Thanks 😊

[@adityabedi8596]

Won't intrinsic lung disease cause decreased elasticity ?

[@MedicosisPerfectionalis]

Elasticity is the opposite of compliance. In restrictive lung disease (including intrinsic), compliance is low, whereas elasticity is high.

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14:11

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