Metformin: Uses, Mechanism of action, Side effects, Contraindications

[@paulaswaim8434]

I am blessed to have no negative issues at all on metformin ER 2000 MG a day for two years now. A1c is 5.7. Lots of awesome benefits and I feel great while taking it.

[@robertstancliffsr9575]

35 years on metformin for me, 2000mgs daily and I'll be 80 in August of 2023. Maybe the longevity side effect is the only one I will have......I can live with that....

[@barbaragermain3713]

Been on Metformin Extended Release for 3 years. Great medication for me. It's been around longer than any new diabetic drugs that are being tried today.

[@titlepending3820]

I love metformin. The vomiting never went away, but the benefits outweight that for me.

[@robertstancliffsr9575]

35 years on metformin, 2000mgs daily and I'll be 80 in August of 2023. Maybe the longevity side effect is the only one I will have......I can live with that....I think vomiting would have gotten me off metformin very quick.......never happened with me...

[@moonlightstargem1006]

I vomited after eating sushi on this medication

[@freespiritwithnature4384]

Keto constipated me,so metformin was good. It increases longevity.

[@Rose-jz6ix]

I have just started taking Metformin 1000mg twice a day. I felt unwell about an hour after taking the tablet with a meal. I thought I would vomit but didn't. I ended up taking an antacid & all was good. My beginning dose seems high. I have been controlling my diabetes T2 for over ten years with diet & working. Now I have PTSD & anxiety I have put on weight because of comfort eating & fear of going outside.

[@robertstancliffsr9575]

35 years on metformin for me, 2000mgs daily and I'll be 80 in August of 2023. Maybe the longevity side effect is the only one I will have......I can live with that....

[@Rose-jz6ix]

@@robertstancliffsr9575 thank you . I have lowered the dose to half tablet in the morning and full one at night. I still haven't told my doctor, but I will. It has dropped my readings & it's good to read from your reply that it's okay long term. ♥️😊🇦🇺 PS I am an August baby too.

[@umaimanaeem8179]

​@@robertstancliffsr9575can you guys guide me here ? before i use this tablet my periods cycle was normal but after having this tablet around one month my periods is irregular like june periods came & july no periods & i am not a PCOD patient doctor just give me this tablet for weight lose now what should i do ? I am taking this tablet one In a day

[@jamesbeam7450]

Man I wish I could understand him better because it seems like solid knowledge

[@MAGAPARIS]

Press the CC button my friend for subtitles

[@morevalueplus8246]

Good video. Simple explanation and easy to understand

[@imranqureshi8624]

Sir non daibetic petient ko metformin 500 de sakte he Isse hypoglyceme hoga ya nhi

[@KrishnaGupta-gj9yt]

Chest pain ho raha hai meri mother ko heart risk ki bhi problem ho sakti hai kya please tell me metformin ke kaaran meri mother ko gallstones aaye hai ultrasound mai aur Sugar bhi sugar control karne ke liye metformin di hai doctor ne but unke chest pain hota hai please batao ki koi risk ki baat bhi hai kya.

[@rafaelzerimar3510]

I've been taking metformin for a month now..2x a day.. surprisingly it helps my vision in my ryt eyes.. suffering from wet macular degeneration.. it help in inhibiting s formation of blood vessels in the macula.. it means metformin have an angiogenesis effect.. that's y I think it can help as anticancer therapy..

[@juniorcarroll337]

Really wish I could understand at least part of what you said.

[@user-do1dc3qf3c]

This drug is simply killing me with diarrhea (really painful ones) and constant nausea. It makes me get up and vomit in the middle of the night, and it has been like this for three weeks (since I begin use this medicine). I am taking it right after my meals (I only have breakfast and afternoon meal) and no nothing helps. I am going to see the doctor again, I will write about the results.

[@winning3329]

Update please?

[@user-do1dc3qf3c]

@@winning3329 My doctor made me quit the drug as he found the side affects excessive. They are suspicious of Helicobacter pylori, so it will be investigated.

[@megoesbrrr]

@@user-do1dc3qf3c so was it h pylori

[@surbhisehgal16]

Take 500 mg instead of 1000 mg . I had diarrhoea with heavy dose. So reduced the dose. You may have H pylori or Hiatal Hernia. Constant nausea happens due to that

[@Tio_Loco]

I had had similar effects when I began taking it ~20 y.a. My doctor at the time had me reduce the doze in half and eventually increase it, as my metabolism adapted.

[@fixman.persian]

please help/when i must eat metrofrim xr ? morning or after dinner? i have insomnia when i use in night ! can i use it at morning single dos?

[@marium2815]

With the meal

[@kristijanakristijanic]

Ask your doctor

[@Detroitjackson]

Mandatory eat good meal. Then take it. Otherwise your stomach will be achy

[@Boost_Concepts]

Thank you sir

[@kathrinat9824]

Does berberine act in the same wy

[@o.a.a5583]

I take metformin just before a meal when i know i will overeat..... actually i take 0.2 voglibose metformin to avoid weight gain from the food.... please tell if i am doing something seriously wrong

[@69footballgoats]

Are you still doing this and is it ok for you?

[@tahmidazim2189]

I accidently took metformin, now i am Feeling weak,now what should i do?

[@LucasSilva-kv3km]

Great video 👏👏 thanks

[@victorb1782]

Thanks for the info but how do you end a video with that and just end the video ?

[@lesw3803]

Doesn’t preventing the AMPKporcess prevent the resolution of fatty liver.

[@elvisnyakundi]

I am here because of anti aging trials😂😂

[@canadafreedomconvoy5827]

you should be here because it lowers long covid

[@wokesoul1599]

Wait what’!! Dose it help with aging???

[@kristy_GT7781]

You should be here cause it helps with lupus😃

[@ImNightFall02]

My ob-gyne prescribed me this medicine for my pcos. Together with provera.. all i can say is... it doesn't feel good taking them both one at a time. Stomach aches, nausea, and fatigue..

[@KapilSharma71180]

Thanks for explaining

[@SahilMulla484]

Can you post more on pharmacology

[@After_Pasta]

So its relicensed phenformin got it

[@markymark272]

B12 supplements is vital!!

[@RandolphadamsII]

What do u mean ?

[@tonystark_2017]

​@@RandolphadamsIItaking Metformin will decrease b12 levels,

[@Rose-jz6ix]

@@tonystark_2017 really? What foods have B12 in them. Last blood tests all my levels were good, but it was before Metformin.

[@tonystark_2017]

@@Rose-jz6ixAns : beef liver Check the nutrition value of it

[@kristijanakristijanic]

​@@Rose-jz6ixeggs, meat

[@VasanthKumar-si9gx]

Thank you so much sir..

[@redredwine1277]

Thank you👌🏽

[@loveisintheair5509]

thank you.

[@jaswinderkaur8723]

Nice explanation.

[@LaberNater]

I have been on Metformin maybe 7 months now? I was 298 pounds back in January of 2024 and my A1C was a bit higher back then, but this drug has helped me bring it down and help me shed weight, ive also been walking more which im sure has helped as well. Im currently at 251 pounds. Ive never vomited from it, but i will say it does make you have some taco bell dookys lol.

[@AeronCorpse]

I been on metformin for 3 months , and I’m just now getting nausea and and diarrhea , and jus t feeling sick .

[@u.s.a.198]

ty great information

[@SahilMulla484]

Too good

[@iramcontractor1346]

Great video!

[@Medinaz]

Thanks!

[@muntakim.data.scientist]

I am obese, and take metformin 850gm twice a day. First I was having gastric problems, now I don't have acidity problems. But my weight is not reducing. But I am not doing any kind of exercise.

[@charlesdrury9712]

Yes I would take vomiting over losing a leg or kidney

[@FranDelSantophotostylist]

I could not get past the first pill it increased my heart rate and then made it harder to breath

[@derekgillan7314]

Brutal medication, spend hours being sick. Pains in joints etc.

[@derekgillan7314]

I ended up exercising, walking, walking then walked home. No longer on meds all okay. Feeling good now, also think before eating.

[@ChristopherSalisburySalz]

I had a lot of GI issues at first. Reduced dosage and then slowly built up to the full dose again. I think I could do it without because I have before but if it can help me get healthy quicker I'll deal with side effects.

[@rameshwaranganesan1809]

For this side effects we may avoid metformin and. Take aurvedic medicene

[@robertstancliffsr9575]

No side effects for me after 35 years of 2X1000 mgs daily......except maybe longevity. I will be 80 in August.....yes, I have kidney function test and i take a B-12 supplement and both my kidneys and B-12 level are fine. When a side effect is listed for any drug, it does not mean you are going to have that side effect........

[@chitraam8574]

​@robertstancliffsr9575 can you please suggest vit B12 supplements

[@sinathamiru2996]

What if someone accidentally took over 5000mg of metformin

[@heavy_hittahz]

Go to rehab

[@robertstancliffsr9575]

They could stop taking it for a few days??

[@janely_euphoria]

The nausea goes crazy

[@manseerkhanm4023]

Metformin reasons my mother died😢

[@tiaj8080]

😮😮😮omg

[@fatumayassin1723]

I’m so sorry for your loss, please explain how and why?!

[@dunn6357]

Whatever you have to take this medicine. If not leads to kidney failure.

[@tr8086]

Poison

[@segaranpillay7154]

UN NECESSARY HAND WRITING

[@redredwine1277]

Thank you👌🏽