Messy Code Is a Feature Not a Bug of Biological System | Manolis Kellis and Lex Fridman

Full episode with Manolis Kellis (Jul 2020): • Manolis Kellis: Human ...
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Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.
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[@Pyrophoro]

"The ambiguity of language might perhaps be the secret of creativity." -Manolis Kellis. Winner Winner, Chicken Dinner! Thank you sir, you are amazing! Never change dude.

[@danhealy2027]

Wait except... DO change, cuz that's what makes you more resilient!

[@thegreatbehoover788]

That was clearly the DUMBEST statement of the entire video! Go ahead genius...see how well your AMBIGUOUS CODE works in PROGRAMMING!!! Lol!!! What nonsense.

[@TheHellogs4444]

@@thegreatbehoover788 Easy, you don't program, you write behaviour your creation must exhibit

[@thegreatbehoover788]

@@TheHellogs4444 I code silly boy.

[@thegreatbehoover788]

@@Kenpachi69420 I'm 6'4" . The only one who ever did jumped COMPLETELY over me. You couldn't.

[@MrVito1180]

Wow. This is one of those conversations that i will remember for the rest of my life. Will never look at misunderstandings the same way. Thank you Lex.

[@antoniogarest7516]

One of the most interesting podcast I've ever heard

[@peppyp7323]

absolutely agree. embrace the chaos of reality. don’t hate it. eastern philosophy is about this too.

[@enigma9369]

It just blew my mind

[@thegreatbehoover788]

@@peppyp7323 Eastern philosophy is UNTENABLE silly. There is inly PURPOSEFUL DESIGN found in life. DNA CODE is the MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever assembled! It doesn't beg the question "What innumerable sets of ACCIDENTS caused this"? No.silly! It begs the question "WHAT SUPERGENIUS DID THIS"??? Your IGNORANCE of the issues surrounding DNA CODE and a cell is your own untellectul undoing here. Your IGNORANCE of the OBVIOUS silliness of attempting to dehumanize yourself in silly eastern philosophy is why you are so easily led into SCIENTIFIC LIES. If SCIENCE were run like eastern philosophy, then we'd end up NEVER discovering anything true. THINK!!!!

[@thegreatbehoover788]

@@jollyrogerexperience This guy is full of garbage. Don't be fooled by his silly ASSUMPTIONS. He understands the WORDS of this SCIENCE but not the SOPHISTICATION and COMPLEXITY NECESSARY for life to even function. He won't even respond to me because he is a PRETENDER...there is no ambiguity or messiness to life...he is just too limited in intelligence to understand what he is looking at. If we ran the space program this way...we'd all be BROKE AND DEAD. No LOGICAL humans wouldnstep into a craft that the last 1,000,000,000 died on...Let alone the last 10....how RIDICULOUSLY STUPID his ASSUMPTIONS are!!!! Lol.

[@badwolf8112]

"first: robust. then: specialize in anything else"

[@Zilberlex]

(time 18:55) - "... Imagine if we could connect brains directly to each other. The amount of information that I am condensing into a small number of words is a huge funnel, which then you receive and you expand into a huge number of thoughts, from that small funnel. In many ways, engineers would love to have the whole information transfer - just take the whole set of neurons and throw them to the other person. This might actually not be better, because in your misinterpretation of every word that I am saying, you are creating a new interpretation that might actually be way better than what I meant in the first place. The ambiguity of language, perhaps, might be the secret to creativity..." - A true masterpiece of a quote. Manolis Kellis - the guy we should have all heard sooner about. Time to meme it up.

[@d4n4nable]

I think it's silly to believe that the same information exists within us in a meaningful way before being transformed into language. If you were to transfer the exact informational content of the neurons to someone else, they might still interpret the meaning differently, when thinking about it in their own minds. It's not like there's a game of telephone between language spoken and language heard. The different interpretation of certain information's meaning comes about when it is brought into language (or "thought about").

[@JKoehmstedt]

Absolutely amazing! I love this quote: "The ambiguity of language might just be the secret to creativity"

[@thegreatbehoover788]

No Jon She He iT than wasn't not! Real have been relax baker ring. See silly....ambiguity and garbage is not cleverness...it is ambiguity and garbage. DNA CODE is the MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever assembled. It PROVES DESIGN. The ORDER of the CODE is beyond anything man has ever done or could do in his lifetime...THINK!!!

[@JKoehmstedt]

The Great Behoover, you’re right, your example is garbage. The sentence I quoted is unrelated to your response though, it needs to be understood within the context. It doesn’t imply that ambiguity is non-complex. It referred to creativity. If you knew exactly what my mind was thinking there would be no ambiguity in how you interpret what I say. But if you have some ambiguity there allows creativity in your interpretation. This statement says nothing about the complexity of DNA or design. If anything it supports DNA being even more complex by incorporating ambiguity and fault-tolerance. If you watch this podcast, I think you’ll be pleasantly surprised at how the arguments put forward support your claims.

[@thegreatbehoover788]

@@JKoehmstedt Your MISUNDERSTANDING is not an INCREASE in information idiot! Lol. Thanks for PROVING my point.

[@brandonkirincich8181]

@The Great Behoover Hmmmm. Very immature.

[@thegreatbehoover788]

@@brandonkirincich8181 And again...you have PROVEN my point!!! Lol. I CODE...coders want ZERO AMBIGUITY because AMBIGUITY BREAKS CODE...it NEVER increases information. How SILLY to BELIEVE so. You comment proves me right.

[@kuzeycelebi5359]

Sending love and respect to this Greek guy from Toronto as a Turkish person :) I like my neighbours!

[@IvanStamenkovicSeemsIndie]

OMG, the genome has a plan guys, it created brain so it can learn about the genome, so it can improve thru science and genetic engineering. Clever genomes :D

[@andresroman9544]

No

[@pranjalgupta5663]

This could just another evolutionary path that nature is trying to speed up evolution

[@nickg2691]

Oooorrrrrr wait for it, it was done in a lab...

[@thegreatbehoover788]

Clever DESIGN

[@thegreatbehoover788]

@@pranjalgupta5663 AGAIN...the personification of nature??? You do realize that nature is not a being...right?? Only BEINGS make decisions silly!

[@1Thor61storm8]

Even though we could transfer ideas directly between brains, I think it will still need some kind of interpretation. If we assume that an idea could be sent as a neural connection pattern, I think it is very likely that the sender is encoding the idea in an almost unique pattern, thus requiring further interpretation.

[@VincentGonzalezVeg]

But essentially what we are saying is we need a simpler/easier ways to relay 'true prelanguage thought' between brains I remember it Areogel looks like it

[@suvedavigneshmaran8036]

Finally! Someone who understands the complexity of the human genome.

[@optimisticfuture6808]

Mr Fridman amazing. Starting the entire interview this evening

[@johndehaan2764]

Another fantastic interview. Lex your subs are taking off. Keep it up

[@VinciGlassArt]

At 20 minutes, the discussion describes working on abstract art. An artist might be the student and the teacher having the conversation with themself, however the result is the same. Our ability for abstraction and inference from this "messiness" which can lead to those leaps of inspiration are truly valuable things.

[@diyandimitrov3724]

Great podcast, great examples and great arguments! Thank you Manolis!

[@soumyaripan5131]

This is amazing. Never understood Genome better.

[@SZMIDEL]

Really love the perspective of miscommunication being the heart of creativity... makes so much sense

[@drjoannakujawaspiritualdet3407]

I love it. 'The incredible beauty if life.' 'Hugely messy' is creative - finally someone going beyond the boring rational design. Love his enthusiasm.

[@deathofkings5633]

Wow that ending especially! The game of telephone might actually have a huge upside!

[@AdamSmith-ul1xx]

A great listen 👍

[@thisisalan883]

Thank you this was fantastic

[@theotormon]

One of those interviews I should listen to until I memorize.

[@thegreatbehoover788]

Only of you want to BELIEVE a pile of SOPHISTICATED sounding GARBAGE! He won't respond to me because he has no answer for the fact that life uses left-handed amino acids...ONLY...in a "seemingly" chaotic world of equally mixed left and right handed ones.....gee.....not very "ambiguous" or "messy" is it??? Lol. He IGNORES all the FACTS that say that DNA CODE is the MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever assembled. He IGNORES the FACT that DNA CODE makes all MANMADE CODE COMBINED look like child's play. How STUPID to IGNORE such READILY AVAILABLE information in favor of silly BELIEFS!!! Ambiguity is CHAOS...creativity is always the result of DIFFERENT THINKING...not CHAOTIC non-thinking!!! Messes are not viewed as creative silly!

[@thomastmc]

15:10 Designing failure into space exploration could mean smaller, cheaper, and greater quantity of missions. By designing failure into the mission you don't need to expend the massive engineering time & effort to ensure that your singular device can't/won't fail. The properties that contribute to failure or success of each individual "micromission" will allow us to quickly and easily improve the overall success in the next generation. For instance, instead of sending 1 Perseverance at $2.2B, we could send 110 "micromissions" at $20M apiece, none of which would perform every task of Perseverance, but have the tasks duplicated into groups of the "swarm".

[@randomguypolololas]

This is awesome!

[@raypraise]

Lex the best on the tube

[@nd493]

Absolute intellectual feast. Thank you Alex

[@thegreatbehoover788]

You can't be serious! He said more things wrong than I can count. Talking about complex subjects while being WRONG is a feast of imbecility.

[@ElmoKnowsWhereYouLive5150]

@@thegreatbehoover788 I'm stealing "feast of imbecility" from you...

[@thegreatbehoover788]

@@ElmoKnowsWhereYouLive5150 Once you FULLY understand that a CODE this SOPHISTICATED and COMPLEX and VOLUMINOUS is onlynthe result of a SUPERGENIUS INTELLIGENCE...then only the WILLFULLY IGNORANT would call it messy!!! It makes Microsoft Windows look like a juvenile attempt at CODING...comparatively speaking. No need to steal...you have my permission.

[@drwalmgc]

We talk about about tracking the evolutionary process in viruses, however it is only simple adaptation process, mutations that allow viruses for example to easily transmit from human to human. Correct me if I am wrong.

[@squadwipesyt3639]

What I've yet to hear from any of these conversations is how the human genome works with the biome comprised of fungi, viruses, and bacteria to create a human.

[@mikhailsharon4331]

Robustness as opposed to perfection: BRILLIANT!

[@garret1930]

This reminds me a lot of Dave Ackley and the Moveable Feast Machine

[@CorryDMG]

Messiness indeed has it's usefull purposes in various fields. For example in the process of downsampling a 24-bit audio signal to a lower 16-bit resolution signal, a random 1-bit noise is added to the signal beforehand which reduces the blockiness of the downsampled signal and preserves more of the original signal in the audible frequency spectrum through modulation of that random error (at the acceptable cost of increased noise in the very high and unaudible part of the spectrum). Similarly, when controlling an unstable system, adding random noise to the control mechanism can increase its accuracy. This is not limited to engineering. When riding your bike along a narrow line, continuously shaken your handlebars very lightly can improve your control to deviate as less as possible from this straight line. This is because the action-reaction time delay is shorter when you only have to modulate an existing (random) control action compared to starting a new control action form zero. This can keep you dry when riding your mtb over a narrow beam across water :p

[@xenajade6264]

Fascinating... need to listen to it again. Right at the end Manolis said "repopulate Mars"...

[@thegreatbehoover788]

Let's get you to get in the first ship! HAHAHAHA!!! Remember the MANY FAILURES??? What an idiot this silly fool is. Ambiguity and messiness creates a mess...notbthe MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever assembled...DNA CODE.

[@Alexhart123]

Incredibly insightful

[@jtzoltan]

"The ambiguity of language could be the secret to creativity" (just before 19:50, listen for 2 minutes ahead of it for some great setup). That is a very good point and one that's occured to me as well. When someone converts their understanding into language and it then runs through the other's language processing, it will stimulate all sorts of ideas and understanding that is bound to be somewhat different in many ways: understood "in a different sense", or even the occasional misunderstanding that is generative of ideas, or even the other person's own concept network/models discovers a stronger iteration. It's also the case that a younger mind who has received some expressed ideas from a speaker has the benefit of a somewhat different set of experiences, ideas and metaphors that are more typical of a new generation which gives them a different perspective or set of tools for thinking about or expressing another's idea. There are so many ways in which this can be generative of variation and new approaches to receiving an idea that can then allow for a different view to corollaries of that idea, implications, consequences, etc. On the flip side, it's amazing how well communication of an idea often preserves the intended meaning of some idea such that so many people within a culture can agree on the meaning of ideas/concepts down to the minutia.

[@unibomberbear6708]

I use a similar metaphor to express how I think Nature works. I use the metaphor of the Fuel injection computer on Automobiles.

[@ErikGraeff]

"let all hell break loose....that's the path to paradise"

[@thegreatbehoover788]

Chaos is hell...thus the saying. DNA CODE is the MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever assembled. It doesn't demand an ACCIDENTAL cause as silly naturalists ASSUME BY FAITH. It DEMANDS a SUPERGENIUS DESIGNER. You are merely an uneducated BELIEVER, or one of the WILLFULLY IGNORANT educated. Either way...pitiful.

[@marshallscot]

I had the thought that the human body comprised of many different types of cells which share the same genome is similar to the scifi oncept of grey goo. Many nano machines which are fundamentally similar but which are able to communicate and specialize in such a way as to create a larger more complex 'organism'.

[@marietta5316]

Fresh. Thanks.

[@baconwilliams5411]

Why does the thumbnail look like a rip off from Joe Rogan Podcast?

[@-mwolf]

Damn that's interesting!

[@adlbray1423]

I feel smarter now after listening to that.

[@menzithesonofhopehlope7201]

Dr. Kenneth Stanley mentions something along those lines, that evolution has no particular end goal.

[@thegreatbehoover788]

The pure silliness of you fools participating in the personification of "evolution" and "nature" is hilarious! HAHAHAHA!!! DNA CODE PROVES DESIGN silly boy. PRETENDING that it your ridiculous "ACCIDENT OF THE GAPS" FALLACY is based in evidence is hilarious! It is quite clear that inly an emotional neediness for a Godless universe causes your acceptance of such UNSUPPORTED drivel. You simply take BY FAITH ALONE that your silly BELIEFS are true. There is no EVIDENCE for an ACCIDENTAL cause of life...let alone DNA CODE. Only someone WILLFULLY IGNORANT would look at life as being ACCIDENTALLY WROUGHT. But...you are more than welcomed to post your UNASSUMED SCIENTIFIC EVIDENCE for the "ACCIDENTAL" formation of DNA CODE (in order) and/or a cell. Oh that's right...you CAN'T!!! Lol. The insanity of BELIEF in the "ACCIDENT OF THE GAPS" FALLACY is simply too funny to me. How do you expect people to take you seriously when you BELIEVE such drivel??? You are more than welcomed to pist your EVIDENCE...this silly man certainly didn't (nor would he respond when questioned)...maybe you'd like to do what he couldn't...POST YOUR UNASSUMED OBSERVATIONAL EVIDENCE that backs your ASSUMPTIONS!!! I am awaiting the EVIDENCE that no other silly naturalist has ever been able to post....due to the COMPLETE LACK thereof.

[@scottretford366]

OK I get the gist of it great knowledge/interview. But what is the most profound genome mutation in humans? RH factor?

[@scottretford366]

Or is it not a mutation and what would that mean?

[@maythesciencebewithyou]

@@scottretford366 It's usually not one gene that leads to a certain phenotype. It's many different genes working together and their regulatory elements regulating them that underly a certain phenotype. You'd first have to ask yourself what you consider to be the most profound thing about humans. Different people would give you different answers. Then you'd have to see whether that thing is special to humans or not. From one generation to the next you don't just get one single mutation. Basically there is not a single profound mutation, but many. And the RH factor itself is one of the least profound ones. Is that the only gene you know of or why'd you mention that one?

[@scottretford366]

@@maythesciencebewithyou Ahh I looked right past the most obvious mutations like birth defects etc. My youngest son is the freshman biomechanical engineering student, I try to learn something of interest everyday to continue to inspire and expand my knowledge as well. I mentioned RH factor because I'm A- blood type. I researched how, no Rhesus D antigen from parents causing a Nonsense type mutation. But why is personal for me due to the fact I can't find non identifying information on my biological parents 43 years later. I'm still very curious of origin, I don't care if dad's Darth Vader no fear at this point. I guess logically 23 and me will probably get me closer than the blood line. Thank you for responding, I got allot of really good knowledge from your comment.

[@jamieharvey4809]

Lucky students to have Manolis for a lecturer

[@jamesmccuen1]

At 3:44, the CC shows the word "theromorphizing" and I can't find a good definition -- the only reference I could find was its use in The Biological Basis of Human Sociality, with the line: "Behavioral resemblances between man and other vertebrates do not lead to anthropomorphizing other animals; they do lead to “theromorphizing” man. Cultural conditioning is then viewed as an exploitation of the more generally vertebrate, and as a thing that tends to disguise the more basic and general." Does anyone have a formal definition?

[@ManolisKellis1]

The transcript was incorrect, I used the word "Anthropomorphising" instead = Giving human attributes (e.g. intent, design, intelligence) to non-human processes (e.g. viruses, genomes, evolutionary processes). Its antonym is not thero-morphising, it's therio-morphising (θηρίο=beast)

[@jamesmccuen1]

@@ManolisKellis1 yeah, he wasn't using anthropomorphizing, though, and that wouldn't have made sense in the context

[@ManolisKellis1]

@@jamesmccuen1 the "he" you're referring to in the video is Manolis Kellis, that's me. And i know I said "anthropomorphising" not "theriomorphising", referring to another part of the conversation when Lex was anthropomorphising viruses by calling them intelligent. Here I was anthropomorphising the process of evolution, by calling resilience its "design principle" when in fact there is no design, robustness is an emerging property selected by natural selection

[@NEOFIXmusic]

@@ManolisKellis1 This is unrelated to the discussion, but I really enjoyed this podcast, it was a pleasure hearing you talk so passionately about these topics.

[@jamesmccuen1]

@@ManolisKellis1 Well I'm an idiot, thank you for replying :-) I still am not sure I follow what you were saying, though

[@JonesNoahT]

If you start to put the wrong AAs in the active sites of your proteins, you might notice that your “robust” biological system is not quite as robust as you had first imagined.

[@sukantasaha5678]

I suppose this was a great topic for the host to discuss while high.

[@jon782]

what he's saying is right but, often even in biology it doesn't work and often major changes to the genome just means that organism dies and doesn't reproduce. Or in the case of cells in animals often it means that the cells will be programmed to kill themselves. In organisms the complexity of how species evolve from one to another isn't known and actually doesn't seem possible since most changes say to a fetus that are noticeable leads to the mothers body aborting the fetus.

[@JappaKneads]

Since when does code have awareness?

[@thzzzt]

So there is no biologic GOTO statement, but there is a COMEFROM, is what I hear you saying.

[@karenkurdijinian2069]

Thank you very much If the body doesn’t produce spermatozoids is it possible to bring back when it’s very less or nothing . My question is ,.....Is the body itself is capable to produce without classical medical interference and how far went the genome longevity how many years ? With todays knowledge ? 🙏🌻🌻🌻🌻🌻

[@udaylunawat2163]

Does the funnel concept that he discussed reminds anyone of the information bottleneck theory in deep learning? Or is it just me?

[@Raylen_Fa-ield]

Lex I love your interviews, but you seem to have difficulty understanding some of your guests and it shows in your questions

[@danhealy2027]

Just like a lot of us listeners!

[@Raylen_Fa-ield]

@@danhealy2027 fair point, and Im grateful for all the knowledge glimpsed from it. That said, I'd love more indepth questions

[@TheHellogs4444]

@@Raylen_Fa-ield I'd love for him to accept question from audience for his upcoming guests. Some 5 min of audience questions thrown in at relevant times would make this so much better than him just reading his guests' bio/CV before interviews

[@eamonglavin2532]

Woah so this 614 d to g mutation causes covid to be more effective at transmission in humans than the original host bats?

[@apologise2bisons]

who wrote that messy code?

[@FrenchingAround]

Lex, you look like you need a nap

[@benjaminrichard7741]

I’m happy I clicked on this video

[@danluba]

Programmers don’t embrace messy code, for sure... that’s because it’s a whole lot more fun to reuse DNA in a new project than it is to sit and salvage functions from a 100,000 lines of spaghetti C++ 😜

[@erikholmberg81]

Funniest thing I read this month.

[@TheHellogs4444]

I'd say that evolved because when programming started out there was no way to index-by-usage, and now look where we are with functional/reactive paradigms

[@thegreatbehoover788]

@@TheHellogs4444 No silly. The MOST SOPHISTICATED and COMPLEX and VOLUMINOUS CODE ever didn't SELF-CREATE and SELF-ASSEMBLE into BILLIONS of lines of the most amazing 4x4x4x4 hypercomplex CODE we've ever seen! DESIGN is OBVIOUS. The video's author is a wannabe that is being PURPOSEFULLY ignorant of the incredible UNMESSY CODE we find....A code created before ALL LIFE that makes Microsoft Windows look like child's play. THINK about that IMPOSSIBILITY through, "natural" causes. How STUPID to assume messiness and ambiguity simply because it blows your mind with sophistication, complexity, and sheer volume while producing the greatest results anyone could even imagine. Mankind CAN'T even do yet what we see done in DNA because it is IMPOSSIBLE for us to form by the silliness PRESCRIBED by naturalism!!! Lol.😅

[@parityviolation968]

I'm still waiting to see the creativity and advantage of messy bureaucracy... It is by far the system we "developed" that is most similar to the "blind", unguided processes of biology; the way it grows, yet seems utterly unable to de-complexify itself even a tiny bit. Or maybe it's because we dont do it messy enough, no freedom... just trying to micro-manage everything (which itself infinite in possibility and ever changing in actual state), but ultimately succumbing to inevitable contradictions in a similar way as Gödel's incompleteness theorem.

[@TheHellogs4444]

bureaucracy is something we engineered and is determinstic. The humans within are not, and they make the system resilient/stochastic. But often they hate the "system" too, they're reduced to robots

[@tagjohnson3246]

Just wow.

[@josuegonzalez5576]

If the genetic code is a code who is the coder?

[@Omnicurious]

This is trying to explain biology to someone who already understands computer science. I'm imaging the reverse where someone try to explain computer science to a biologist with this method. "So they have this thing called C which is like DNA, then it goes through this thing called a 'compiler' which is kinda like the splicesome, and it gets turned into machine code which is basically mRNA..."

[@obi_na]

Where is Nassim Taleb! !!!

[@noamovich28]

confusing runtime and code. runtime should be robust the code should be as simple clean.

[@Jamie-Russell-CME]

Oh please! That is evidence of design. Why should that develop?

[@ArizVern]

SPACEX: FAILING CREATES, MEANDERERS AND ROBUST, IDEAS.

[@jessicahardesty3998]

"I'LL STAB SOMMEONE" PLUS I WROTE THE HUMAN GENOME JLH LE SE MV

[@sethjets4687]

jesus fucking christ my mind was blown right away with this one!!

[@dubemelchi]

H O L Y ISH! I I understand, but I dont, but i do. man, you are great at conveying ideas! damn!

[@thegreatbehoover788]

It's all garbage. Ambiguity and messiness cause NO LIFE...not life.

[@mathematicalninja2756]

The Great Behoover shut up

[@joshnordin4043]

The human genome contains 215 petabytes of information (215 million gigabytes). Just a relevant fact to the video.

[@caricue]

This guy is super smart and a joy to listen to, but then he will throw in something so mindless, like DNA being digital or living processes being "messy", but messy to whom? It's more likely that it's ordered in a way that is so subtle and elaborate that it looks like a mess to us hairless apes. DNA is a physical template to order amino acids. There's no information there, it's in the eye of the beholder. You have to wonder if such conceits inhibit advancement, but like I said, very impressive researcher.

[@tomatoso27]

Is it weird that I've got sexually arused by the concept starting at 19:00 ?

[@pranjalgupta5663]

Lol, I thought I was the only one to get turned on by all this insights

[@danhealy2027]

That's because you're thinking of the movie "Avatar"

[@iridium9512]

Makes sense to me. Sexuality is built around intimacy, and what is more intimate than this?

[@ElmoKnowsWhereYouLive5150]

Ask Rick or Morty.

[@romanilies119]

So this guy is like smart or something

[@jacobsaintjames]

The brain is totally digital. Action-potential is all-or-none. Information travels in discrete packets. Reality is simulated at a maximum frame-rate of around 300 fps, defined by the absolute refractory period of a neuron. The universe in itself is analog if you ignore quantum physics. But life will always be a lossy format.

[@unibomberbear6708]

- These guys get smart enough to figure things out just enough to break something. Just Like a shade tree mechanic. Example: They created vegetables and fruits that are barron of seeds, and although it seems like an awesome idea to grow watermellon that you can munch on and not have to spit seeds all over whils eating , however think about that now. It affected something else in fruits other than seedlessness. The tomatoes are flavorless , and you can play tennis with the damn things. Ethics was never even discussed . I'm stopping because I have no way to make a point about the highest priority being put on ethics when they tinker around with natures self correcting system , tinkering with a Novices ability , messing around with a self correcting Natural system that is running just fine , and these guys remove their oem muffler and install some loud 'performance' one cause he just watched Fast and Furious. Now the thing runs like shit , and panic sets in cause he has no idea what , and he just randomly changes a sensor parameter , oops now its on fire..and so on .. Ethics ..Think about them . "We don't need no water Let the motherfucker Burn.. Burn mother fucker Burn !."

[@inmysoul7]

You obviously have no clue what you talking about. Just relax and quit smoking.

[@jensklausen2449]

Sometimes I think that the most fundamental known messiness in nature is not always blindly random without any purpose or goal. By that I mean, how the collapse of the quantum mechanical wave function happens. Maybe there are are many realms of intelligent life beyond the physical universe and maybe a higher intelligence among them knits their input into the physical world together in a way such that different channels of input become creative here. Like in intelligent design of the digital DNA code, where maybe more classy intelligent input often are rewarded with longer long term survival? But the professor is maybe to scared to go there unless in private, because it can be a career destroying taboo to break.

[@robbie_]

The claim that we're a digital computer is twaddle.

[@devanw6542]

Messiness applies to cultural evolution too?

[@blngmz1777]

Amazed, inspired, and filled with joy. Thank you

[@jual-rakid]

If you want to compete with nature, you have to be able to build from molecular level

[@wajihbec1087]

Embrace messiness. This dude is a GENIUS!

[@TheMedWolf]

Not quite true the evolution is only the product of random mutation and ruthless selection. Mutations are decidedly non-random on all scales of time and place and this suggests the possibility of agency. I gave a talk on this point actually: kzbin.info/www/bejne/gIGlg2uqZ7llqNU

[@shabanaa723]

The anger that the people have by the unreasable answers of who we are; are flames! those flames opening the conscioesness of the infinity of our mind, giving us the soul Power of definition of our Life by constructing else our shapes and our collect intelligence give by biological genes.

[@No_OneV]

Interesting

[@user-kn9ib9zm4q]

Γεια σου πατριδα

[@paulalves966]

Hey guys, don’t use this as an excuse to write shitty code! 😅

[@donikajorgo5612]

DNA it's mathematics 0 A B BB D.

[@maidomelker1063]

I'd take a direct brain download from both of you anytime 🤯

[@stridedeck]

Messiness within boundaries!

[@robertsmyk4102]

It takes a decision maker to write code and evaluate changes in the code. Where is the logical device that works t

[@mikey5913]

Lex's questions suck sometimes

[@voodoo273]

An unheard-of mutation just happens to happen... specifically to one gene that allows human transmissions.. Yup its from a lab change my mind

[@8w494]

Fail quickly

[@jessicahardesty3998]

LEX

[@ikevin127]

Orgy - Fiction (Dreams In Digital) | Life Rips

[@libbygolightly]

W🤯W

[@lorenzvo5284]

This is a very informative podcast but lex looks like he smoked a big jimmy

[@bugr33d0_hunter8]

Always trying to mess with God's creation.

[@faithful1137]

I feel like God put it on my heart to say this everyone has corona viruse and it is a woe a punishment for human experimention I can't say why people get it to mutate to cv19 but we all have CV now it will continue to mutate and develope on those that make opposition with Jesus

[@nickg2691]

Listen to what this guy is saying, a mutation that has not taken place for BILLIONS of years, suddenly decided to happen in an election year lol.