Metformin - Mechanism of Action

Metformin
Anti-diabetes medication
Biguanides

[@bio366geethasankar7]

😊🙏🏻

[@姜周禮]

Actually, metformin not only act on AMPK. its' mechanism is more complex.

[@nyloxyloto4871]

But even my text book shows this mechanism. What is the more complex mechanism?

[@kevinspaleta]

Try Complex 1 ;)

[@patateskizartmasi7890]

😱😱😱

[@WXUZT]

It suppresses Glucagon or its action...apart from other actions. It mode of action IS complex. Try this reference: stm.sciencemag.org/content/5/172/172ec31

[@nenadcubric2663]

Reduce the Liver to produce glucose,

[@ys3593]

How does metformin reduce ATP?

[@nenadcubric2663]

So Works also for Insulin Resistance?