Mitochondrial: Cell Danger Response

[@samhouston1483]

Thank you Dr for studying this and ofc the great Dr Naviaux. I suffer from ME/CFS after SARS2. Hoping this work may lead to some discoveries than can help w this.

[@richieheetebrij8189]

Another piece of the puzzle. Great stuff. I can’t believe more people are not on this. A lot of chronic “diseases” are this for sure. I hazard a guess that if not dealt with that cancer will be the final outcome of years of this. I believe the mitochondria must influence/ effect the endothelial in some sort of way too. Toxic lipids also. In very recent times it also seems that uric acid may also play a roll in this danger response, or not being able to regulate it. Allopurinol with vitamin c and the bioflavonoids might have some efficacy as well. Urolithin A may work for some people. Interesting times, so much to learn. So much recent game changing science. Search supplements for mitochondria disease.

[@Psychologist_ClarissaMosley]

Oh, the last few words, how do we revert the genomic alterations to get the Mito out of CDR?

[@rahman.pakzad]

That must be a gigantic mitochondria :), i guess its a typo, its not in mm but um.

[@sirvikalcrusader3668]

agreed but I think we all know what he means

[@Peter-zw8yn]

So is there a treatment to reverse this? I'm a little lost at the conclusion, the only drug I've seen to tackle this is suramin and that's impossible to get.

[@filterofcrap]

@@deepdusto so what bigger threats are you suggesting exist and influence that are not being identified in this presentation? What theory do you have or would be the basis of your debate argument?

[@filterofcrap]

I dislike the ending cliff-hanger. At least give suggestion to another talk or presentation on how to restore gene expression and improve transcripnomics.

[@monkeybearmax]

@@deepdusto what does that mean? Are u suggesting it’s better not to correct this response?

[@monkeybearmax]

@@deepdusto I definitely agree with that. My qw was bc I was thinking you saw potential danger or other negative consequences from correcting this.

[@CIRSlab]

In the context of Chronic Inflammatory Response Syndrome/CIRS (which is what he's using as a reference), VIP (Vasoactive Intestinal Peptide) would be the drug that does the job. VIP has been tried on other chronic illnesses like chronic fatigue and long COVID (which some argue are ultimately CIRS), but the evidence is still premature, though promising. So my guess is peptides are one possible solution to the puzzle.

[@huna1950]

I could listen to Andy all day…and have many a day-must admit like someone else I was a bit peeved at the cliffhanger stuff at the end. Assuming he was going to follow up and has so far not I’ll say!?!? Anyway…I’m off to order after 3-4 years of not taking it ATP by Cellcore mitochondrial-see how I go I suppose. Their Biotoxin binder is bloody good.