N-Acetylcysteine for ADHD?

[@patkelley8293]

I take 750 mg NAC per day for almost a year now w/ other supplements. I've noticed I am calm throughout the day. I don't lose my temper. That's big for me. But I only take the supplements once a day so I cycle up and down. I could take a second tablet but one is working more or less. I've also noticed I don't have breathing issues. I work around steam coming off shrimp cookers that are heavy in histamines from the shrimp. It's actually dangerous for some but I have noticed less congestion. And the Weighted Blanket has been an absolute game changer! Thanks for the great advice.

[@CamStubbs]

Other supplements?

[@patkelley8293]

@@CamStubbs My morning stack: L-theanine 200mg, L-Tyrosine 500mg, NAC 750mg, Tumeric 550mg, Ginko 60mg and Magnesium. Also for pick me up Creatine Monohydrate 5g w/ one scoop Vegetable Protein (no soy or whey) That's for focus. I added Magnesium to combat severe leg cramps due to my work.

[@RahulRanjan674]

Please make a video on persistent depresive disorder and ADHD (with meds) Thank you so much for all the work ❤

[@Cutest1TheGame]

Thank you for dividing the video into chapters! I feel relieved and excited. When I read a video title, I’ll have a specific question pop in my head and because you created chapters and labeled them accurately, I could jump straight to my question “What is N-Acetylcysteine?” to find the answer. If I see a video is long and I know I don’t have time right now to watch the whole thing to find what I’m looking for, it ends up in the watch later list and mine has almost 1300 videos there, so it gets lost.

[@DrJohnKruse]

Max Poli from France, who has been editing my videos for sound quality is also completely responsible for all of the good work putting chapter headings in the description. I'm glad that they helped you.

[@trueXMotionFitness]

Or if the video is long & you fear your attention span will be too short, haha. That was me. But as with many of his other videos, I get pulled in & find myself wondering how it went by so fast.

[@gianni_schicchi]

It works for OCD and intrustive thoughts, which my ADHD comes with.

[@DrJohnKruse]

OCD is where I've seen the most benefits. I'm glad that it has helped you.

[@roxanne_george]

Sounds like a great option! ❤

[@TonyRea-ok1us]

Sold.

[@thebiggestpicture3230]

@@DrJohnKruse FDA attempts to ban NAC as a supplement is because it was effective against c0vid (notice how the dates coincide with EUA requirement period), one of many censored effective treatments that together could've reduced the death toll by well over 90%. You missed this fact due to the limited sources of information you were paying attention to during that event.

[@aurielhurrell]

Interesting as NAC is being recommended for removing the spike protein post the nasty jabs.

[@Idrinklight44]

NAC and boosting glutathione, may be the single best thing for the liver.. ...it definitely was for myself.

[@TheLiverDaily]

That's great to hear! Was there anything in particular that stood out about its liver effects?

[@SideB1984]

In the first week of 600mg, my HRV jumped significantly, indicating parasympathetic recovery. I started dreaming more, or remembering them. Recovering from vax injury in the setting of CVID and hEDS, and post viral from dengue fever a decade ago. Mainstream left me to fend for myself. Myocarditis and Hashimoto’s just cleared up. 🎉GABA is my other new fave. Still hoping to ramp NAC and see improvements with OCD.

[@DrJohnKruse]

With more conventional medications, OCD often takes a longer time to respond than does depression, so it is possible that with more time on the current dose of NAC you will see improvement there as well.

[@broccoli-dev]

Dr. Kruse, could you do a video on chamomile and anxiety/depression?

[@plymix8389]

Gonna drop a quick tip for the comment section. These NAC tablets can be rather large and hard to swallow. What can be of tremendous help are thick milk shakes. My favorite is the vanilla flavored ensure nutrition shake. It provides lubricant, and it’s thick enough of a drink that it actually tricks the mind, so it feels more like a gulp of water opposed to swallowing a pill.

[@mccaine1]

paracetamol, though they will recognize acetaminophen. I had to find some in Spain years ago.

[@SK-wc3hs]

One of the biggest downsideds with nac is that i feel like it really makes my adhd medications not work.

[@DrJohnKruse]

I'm sorry to hear that, and am trying to think of mechanisms that might explain it.

[@thejayroh0011]

Hello, and thanks for the info! I've frequently supplemented with N-acetyl cysteine for over a year, and I was diagnosed with ADHD at the age of nine. My anecdotal thoughts: Even at 36 years old I can't say that NAC has an obvious impact on ADHD symptoms, but I do feel like 1000mg of NAC every morning may have helped my liver recover from a bout of alcoholism in my late 20s to early 30s. Other than that I feel like NAC is....there. It's probably having an impact, but nothing game-changing.

[@The_Albanian_Inquisition]

I've had a doctor suggest this to me for drug craving

[@wesleydevries7415]

Great video!

[@DrJohnKruse]

Thanks, and thank you for showing up at the Q&As with good questions.

[@Cutest1TheGame]

@5:25 In Germany, I’ve only ever heard it called “acetaminophen” and haven’t heard any associated brand names for it.

[@thomasa5619]

Paracetamol The full name Is something like acetyl para aminophenol

[@Starfish2145]

Brits call paracetamol

[@scootyz1983]

What would you suggest to be a safe yet effective dose for anyone wishing to experiment with NAC? Are the effects immediate, or would it take time to build up in your system?

[@DrJohnKruse]

In the study of patients with ADHD and lupus, they looked at 2400 mg and 4800 mg a day. When both doses were lumped together, they were statistically better than placebo, but it looks like that was almost entirely due to the 4800 mg dose. Most of the supplements I've seen are 600 mg. Most individuals I have worked with started with 1200-2400 mg for a month, and then adjusted if they thought that would be helpful.

[@marydolores11]

@@DrJohnKrusethank you, Dr. Kruse!

[@puddles5501]

Great insights

[@CamStubbs]

Thanks doc 😇

[@TheLiverDaily]

I've been researching NAC and how it can benefits people with liver disease. Did you find any good information on its effect on the liver in your research? Thanks! Great video!

[@Idrinklight44]

Germany likes it's milk thistle for the liver. Ever try Hulda Clark's liver flush?

[@TheLiverDaily]

Milk thistle is great for preventing liver disease, but most docs will advise you to stop once diagnosed to avoid putting further strain on the liver. I'll make note of that brand though and include it in a video about prevention! 😊

[@DrJohnKruse]

The way that NAC rescues the liver from Tylenol damage is by boosting glutathione, which can neutralize many (but not all) liver toxins. The anti-free radical action and anti-inflammatory action also should aid in liver reovery.

[@Calmrecordings]

Would large quantities of MSG cut out the middleman and increase glutamate levels? (Casting side the sodium issue for a moment)

[@DrJohnKruse]

Too much glutamate can be harmful. Glutamate in blood plasma is not the major source of brain glutamate. pmc.ncbi.nlm.nih.gov/articles/PMC5192417/#:~:text=A%20facilitative%20transport%20system%20exists,the%20luminal%20facilitative%20glutamate%20transporter.

[@theJellyjoker]

I just have a Knack for it. 🤣 ha! [1:59] Ooh, ba do de do be ba ba do ba ba Ba ba ba ba da My N-Acetylcysteine!

[@philip6252]

I take it for LC but I also experience the nausea.

[@bbylamictal2037]

My cocaine abuse patient is prescribed NAC for cocaine cravings

[@trueXMotionFitness]

It looks like you're tapping your foot or bouncing your leg. I had to stop tapping mine first to make sure. 😅

[@mebeasensei]

Could it also help with autoimmune conditions?

[@DrJohnKruse]

Theoretically. There is some evidence that it can help with lupus.

[@lindarothera7838]

It was suddenly unavailable during the pandemic

[@user-bd4bo4tb8u]

Thank you so much! Do you have any suggestions to ease Adderal withdrawal? Specifically, the extreme fatigue, brain fog, and hypersensitivity? I've tried Wellbutrin, but it doesn't do much. Thank you for all the information.

[@DrJohnKruse]

I won't offer the cliche that time heals all wounds, but most people do find that withdrawal symptoms diminish with time, and remembering that can help some people through it. Some people are helped by guanfacine. I'm not aware of controlled research on withdrawal strategies when stopping stimulants, but certainly tapering helps with many other classes of medication.

[@kenhaze5230]

Typically, I can't see good. Unfortunately, it's important to me to be able to see good. When I take NAC and R-lipoic acid, I can see good. I don't notice effects on ADHD.

[@SeanRhoadesChristopher]

I bought NAC during Covid, for some reason I still have it. I’ll try it out and see if it helps.

[@DrJohnKruse]

Some people were promoting it as an aid to clearing airways / help with breathing, since COVID's major target is the respiratory system. I didn't run across any controlled studies of that use.

[@taghiabiri3489]

My Sharonaaah ! 😂

[@joesandbank3645]

Interesting…

[@YrisOrus]

Paracetamol